Clinical trials: Remifentanil
Pain
Pregabalin and Remifentanil - Analgesia and Ventilation
In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.
- Trial name
- NCT01419405
- Testing
- Pregabalin, Remifentanil, sugar pill, saline infusion
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Labor Pain
Continuous Remote Vital Sign Monitoring During Labour Analgesia With Remifentanil
Continuous remote vital sign monitoring during labour analgesia with remifentanil - a prospective observational study Remifentanil PCA represents a well-tolerated, effective and valuable option for labour analgesia, yet its wider…
- Trial name
- NCT07167498
- Testing
- Intermittent midwife absence during remote monitoring of remifentanil PCA in labour
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Breech Presentation, Pregnancy
Remifentanil Versus Paracetamol for Pain Treatment External Cephalic Versions.
BACKGROUND: Between 3-4% of pregnancies carried to term, the fetuses are in breech presentation. The external version is a maneuver gynecological used to turn a breech in cephalic presentation.
- Trial name
- NCT01048398
- Testing
- remifentanil, paracetamol
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Complication of Labor and/or Delivery
Efficacy and Satisfaction With Remifentanil Analgesia in Parturients During the Childbirth
Retrospective observational study to determine the efficacy of remifentanil during the delivery. Authors will search the data in period between 2010 and 2014 in cohort of 100 parturients and obtain data of analgesic efficacy (VAS…
- Trial name
- NCT02447757
- Testing
- remifentanil
- Where
- 2 sites in Czechia
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Brno University Hospital
Anesthesia
Role of LIDOCAINE IN Pediatric Cochlear Implant Surgery
The stapedius reflex protects the ear from the loud noise. The measurement of the intraoperative electrically evoked stapedial reflex threshold (ESRT) during pediatric cochlear implants (CIs) is used to confirm that the implant…
- Trial name
- NCT04194294
- Testing
- Lidocaine, Na CL 0.9%
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wahba bakhet
Conscious Sedation Failure During Procedure
Remifentanil Effect-site Prediction by Algometry
This study validates the pharmacodynamic analgesic predictions (effect) given by Minto's remifentanil pharmacokinetic and dynamic model in conscious sedation.
- Trial name
- NCT05115578
- Testing
- Remifentanil 1 MG Injection [Ultiva], Midazolam 1 MG/ML Prefilled Syringe, Saline solution
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Nasal Polyps
Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery
Functional endoscopic sinus surgery (FESS) is indicated in diseases such as chronic sinusitis refractory to medical treatment, nasal polyposis, mass lesions in the nasal cavity.
- Trial name
- NCT02484859
- Testing
- Remifentanil, Tramadol, Metoprolol
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Cholecystolithiasis
Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to…
- Trial name
- CLTCI (NCT02114437)
- Testing
- Closed-loop TCI, Opened-loop TCI
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Adolescent Idiopathic Scoliosis, Multimodal Analgesia
Propofol + Remifentanil vs. Propofol + Dexmedetomidine in Adolescent Idiopathic Scoliosis Patients Having Spine Surgery
Patients with Adolescent Idiopathic Scoliosis may need surgery to correct their scoliosis. General anesthesia is required for this surgery, and a multimodal analgesic regimen using combinations of opioid and non-opioid…
- Conditions
- Adolescent Idiopathic Scoliosis, Multimodal Analgesia, Opioid Induced Hyperalgesia, Remifentanil
- Trial name
- NCT06096181
- Testing
- Remifentanil TIVA, Dexmedetomidine TIVA, Propofol TIVA
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Hyperalgesia
The Effect of High-dose Remifentanil on Established Sunburn-induced Hyperalgesia in Human Volunteers (HighDose RemiSun)
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- NCT01015482
- Testing
- Remifentanil, Midazolam
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pain, Postoperative
The Effect of Remifentanil on Rebound Pain
The investigators will evaluate the influence of intraoperative remifentanil infusion on the postoperative hyperalgesia in patients receiving rotator cuff repair after brachial plexus block for postoperative analgesia.
- Trial name
- NCT04236323
- Testing
- Not used remifentanil infusion
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Labor Pain, Labor; Prolonged, Second Stage
Remifentanil vs. Combined Spinal-epidural Analgesia for Labor Analgesia and Progress of Labor in Multiparous
Remifentanil may be an ideal drug for labor analgesia due to its pharmacodynamic and pharmacokinetic profile. As compared to epidural analgesia, it demonstrated satisfactory for pain relief at the beginning of labour with a…
- Conditions
- Labor Pain, Labor; Prolonged, Second Stage, Labor; Prolonged, First Stage
- Trial name
- NCT02963337
- Testing
- remifentanil, combined spinal-epidural analgesia
- Where
- Slovenia
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Hyperalgesia
The Effect of Remifentanil on Established Capsaicin-Induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiCaps2 (NCT00789386)
- Testing
- Remifentanil, Midazolam
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pharyngeal Dysfunction, Pharyngeal Swallowing
Opioid Effects on Swallowing Comparing Younger and Elderly Volunteers
The purpose of the study is to determine whether remifentanil influence the pharyngeal phase of swallowing using using pressure and impedance recordings.
- Trial name
- NCT01924234
- Testing
- Morphine, Remifentanil
- Where
- Sweden
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Oocyte Retrieval, Sedation, Conscious
Respiratory Depression During an Analgosedation Combining Remifentanil and Ketamine in TCI for Oocyte Retrieval
This study evaluates the effect of the addition of ketamine to a conscious sedation protocol including remifentanil during oocyte retrieval.
- Conditions
- Oocyte Retrieval, Sedation, Conscious, Ventilatory Depression
- Trial name
- NCT03458143
- Testing
- Ketamine 150 ng/ml, Remifentanil, Oocyte retrieval
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Obstructive Sleep Apnea
Remifentanil in Children With Obstructive Sleep Apnea
This investigation tested the hypothesis that children with obstructive sleep apnea have an increased pharmacodynamic sensitivity to the miotic and respiratory depressant effects of the prototypic μ-opioid agonist remifentanil.
- Trial name
- ROSA (NCT03958396)
- Testing
- Remifentanil Infusion
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Morbid Obesity
Remifentanil Dosing Regimes for Anesthesia in Bariatric Surgery: Characteristics of Early Recovery
Early recovery characteristics are important for patients' safety and operating room turnover. Our aim was to compare fundamental methods for dosing remifentanil during morbid obesity surgeries: a manual infusion and a…
- Trial name
- NCT04690088
- Where
- Lithuania
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Other Complications of Surgical and Medical Procedures
Comparison of the Effects of Nicardipine and Remifentanil on Surgical Visual Field
In the present study, the purpose was to compare the effects of Nicardipine and Remifentanil on surgical visual field and hemodynamic parameters in microscopic tympanomastoidectomy cases with Controlled Hypotension (CH).
- Trial name
- NCT06130527
- Testing
- Nicardipine, Remifentanil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Erol Karaaslan
Pharyngeal Dysfunction, Pharyngeal Swallowing
Opioid-Induced Swallowing Dysfunction - The Impact of Bolus Volume
The purpose of the study is to evaluate the impact of different bolus volumes and viscosity on remifentanil-induced swallowing dysfunction in healthy volunteers.Hence, whether swallowing tasks can be done safer during sedation by…
- Trial name
- NCT03283020
- Testing
- RemifentanilMNTX
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Hyperalgesia
The Effect of High-dose Remifentanil on Established Capsaicin-induced Hyperalgesia in Human Volunteers
Treatment of chronic pain is a major clinical challenge since chronic pain is frequent and leads to deterioration of quality of life.
- Trial name
- RemiAnes 1 (NCT00886106)
- Testing
- Remifentanil, Midazolam
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna