Clinical trials: Relationship Distress, open to volunteers
Pancreatic Tumor, Benign, Pancreatic Cancer, Adult
Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer
This is a prospective, observational cohort study (MIND-PANC) to explore the associations of chronic psychological stress with disease progression, treatment outcomes, and prognosis of pancreatic cancer.
- Conditions
- Pancreatic Tumor, Benign, Pancreatic Cancer, Adult, Pancreatic Cancer Resectable
- Trial name
- MIND-PANC (NCT07529626)
- Where
- 3 sites in China
- Volunteers
- 320 people
- Sponsor
- Shanghai Zhongshan Hospital
Type 2 Diabetes Mellitus (T2DM), Diabetes-related Distress
Digital Self-Management Education and Support for Young Adults With Type 2 Diabetes (DSMESYAT2DM)
This randomized controlled trial will evaluate the effect of a nurse-led digital self-management education and support program on self-management behaviors, glycemic control, and diabetes-related distress in young adults with…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Diabetes-related Distress, Diabetes Distress
- Trial name
- DSMESYAT2DM (NCT07325838)
- Testing
- Digital Nurse-Led DSMES Program, Usual Care Plus Standard Digital Education
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Recep Turan
Cancer
Remote Mindfulness Breathing Training for Patients Undergoing Chemotherapy
This randomized controlled trial will evaluate the effects of a mobile-delivered remote mindfulness breathing training program on symptom distress, fatigue, anxiety, and depression in adults with cancer who are receiving…
- Trial name
- NCT07806760
- Testing
- Mobile Remote Mindfulness Breathing Training, Brief Mindfulness Breathing Instruction
- Where
- 2 sites in Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Acute Respiratory Distress Syndrome, Sepsis
Multiple Study of Electroaccpuncture in ARDS
In order to clarify the clinical efficacy of electroacupuncture on inhibiting systemic inflammatory response, improving respiratory mechanics parameters and prognosis in patients with sepsis-related ARDS.
- Trial name
- NCT06278675
- Testing
- Acupuncture needles
- Where
- China
- Volunteers
- 264 people
- Sponsor
- Nanjing University of Traditional Chinese Medicine
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Physical Symptom Distress, Weight Management
A Self-management Based Survivorship Intervention for Chinese Cancer Survivors
This study, using a sequential multiple assessment randomized controlled trial (SMART) approach, will evaluate a cancer survivorship care intervention on physical symptom distress, weight management, self-efficacy in managing…
- Conditions
- Physical Symptom Distress, Weight Management, Neoplasms
- Trial name
- NCT05534386
- Testing
- Cancer survivorship care intervention, Step-up targeted personalized intervention, First stage control intervention
- Where
- 7 sites in Hong Kong
- Volunteers
- 486 people
- Sponsor
- The University of Hong Kong
Cancer, Healthcare Professionnals
Assessment of Cancer-related Post-traumatic Stress in Patients and Caregivers in the Year Following Diagnosis, and Identification of Their Expectations of Personalized Support - CANDYSTRESS
The impact of cancer on the lives of patients and their caregivers is undeniable. In addition to the potentially traumatic aspects (i.e., creating a very violent emotional shock) linked to the announcement of the disease and the…
- Conditions
- Cancer, Healthcare Professionnals, Caregiver Distress, Caregiver
- Trial name
- CANDYSTRESS (NCT06944262)
- Where
- 2 sites in France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Lille University
Glucose, Metabolism
Tracing Of Real-time glu13Cose Metabolism in Human Immune Cells - Intensive Care Unit
The purpose of this study is to understand how cells of the immune system use the common sugar glucose during critical illness. Investigators will intravenously infuse a non-radioactive carbon-13 glucose tracer into adult…
- Conditions
- Glucose, Metabolism, Isotope Labeling, Immune System and Related Disorders
- Trial name
- TORCH-ICU (NCT07811180)
- Testing
- 13C6-Glucose
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vanderbilt University Medical Center
Acute Respiratory Distress Syndrome
Association Between Driving Transpulmonary Pressure and Extravascular Lung Water in Patients with ARDS
Intubated patients with the acute respiratory distress syndrome (ARDS) are usually treated with protective ventilation limiting plateau pressure below 30 centimeter of water (cmH2O) and, if possible, a driving pressure under 15…
- Trial name
- NCT05474196
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Bicetre Hospital
Menstrual Cycle, Menstrual Distress (Dysmenorrhea)
Menstrual Cycle Symptoms and Female Health
The complexity inherent to the hormonal fluctuations associated with the female menstrual cycle (MC) has contributed, from a methodological perspective in research, to the neglect of women's physiological characteristics and to…
- Conditions
- Menstrual Cycle, Menstrual Distress (Dysmenorrhea), Premenstrual Syndrome, Abnormal Uterine Bleeding (AUB)
- Trial name
- CICLOS (NCT07699224)
- Testing
- Prevalence
- Where
- Spain
- Volunteers
- 400 people
- Sponsor
- Universidad Rey Juan Carlos
Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders
Exposure Therapy for Reactivity to Symptoms
It is unclear to what degree systematic exposure exercises contribute to the overall effects of exposure therapy (exposure and response prevention).
- Conditions
- Psychological Factors Affecting Other Medical Conditions, Somatic Symptom and Related Disorders, Bodily Distress Disorder
- Trial name
- SOMEX2 (NCT07757854)
- Testing
- Planned, systematic, exposure exercises, Response prevention
- Where
- Sweden
- Volunteers
- 360 people
- Sponsor
- Region Stockholm
Smoking Cessation, Depression
Adapting and Pilot Testing a Skills-based Smoking Cessation Intervention to Address Developmental and Health-related Stress Among Adults Who Smoke
Smoking remains the leading preventable cause of death in the United States, and there are persistent and significant disparities in tobacco use among transgender and gender diverse (TGD) individuals.
- Conditions
- Smoking Cessation, Depression, Anxiety, Nicotine Dependence
- Trial name
- NCT06654414
- Testing
- PRIDE QUIT, Enhanced Treatment As Usual (ETAU)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Post Traumatic Stress Disorder (PTSD), Depression
Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
The VA wants to understand what type of integrative and whole health approaches are helpful for Veterans. The study is comparing two primary care based mental health treatments, a mindfulness class that teaches mindfulness…
- Conditions
- Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
- Trial name
- NCT06162741
- Testing
- Primary Care Brief Mindfulness Training (PCBMT), Moving Forward (MF)
- Where
- 4 sites in United States
- Volunteers
- 300 people
- Sponsor
- VA Office of Research and Development
Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome
The ICU LIBERATION Study
Acute respiratory distress syndrome (ARDS) is a condition associated with hypoxemia due to noncardiogenic causes and results in high mortality.
- Conditions
- Acute Respiratory Distress Syndrome, Post Intensive Care Syndrome, Treatment Compliance, Quality of Life
- Trial name
- LIBERATION (NCT05844579)
- Where
- Japan
- Volunteers
- 1,000 people
- Sponsor
- Japanese Society for Early Mobilization
HIV, HIV - Human Immunodeficiency Virus
Intervention to Reduce HIV Related Stigma Among Pregnant and Postpartum Women
Purpose of this Study: The main purpose of this study is to adapt an existing evidence-based intervention, Project Accept Post-Test Support Services (PTSS) Module 3, specifically for pregnant and postpartum women living with HIV…
- Conditions
- HIV, HIV - Human Immunodeficiency Virus, Postpartum, Pregnancy
- Trial name
- WAT (NCT07064928)
- Testing
- Adapted Project Accept's Post-Test Support Services (PTSS) Module 3
- Where
- Ghana
- Volunteers
- 163 people
- Sponsor
- University of California, San Francisco
Acute Respiratory Distress Syndrome (ARDS), Age-related Impaired Alveolar Epithelial Repair
RSPO3/SDC-1 Pathway Dysfunction in Alveolar Repair After ARDS in Older Adults
Acute respiratory distress syndrome (ARDS) is a serious lung condition in which fluid builds up in the air sacs, making it hard to breathe and often requiring intensive care.
- Trial name
- NCT07129330
- Testing
- RSPO3/SDC-1 pathway profiling assay, Blood and Saliva
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Inflammatory Bowel Diseases
Duloxetine in Inflammatory Bowel Diseases
This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflammatory bowel disease (IBD).
- Trial name
- Duloxetine in (NCT07431606)
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Pennsylvania
Primary Headache, Psychological Distress
Impact of MBI on Biopsychosocial Factors and QOL in Children With Primary Headaches
The Randomized Controlled Trial aims to evaluate the effectiveness of a Mindfulness-Based Intervention (MBI) in improving the quality of life and reducing psychological distress in children with primary headaches.
- Conditions
- Primary Headache, Psychological Distress, Emotion Regulation, Childhood Trauma
- Trial name
- NCT06822673
- Testing
- Mindfulness Based Intervention
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatima Jinnah Women University
Breast Cancer, Cancer Distress
Utility of a Mobile Application for Young Women With Breast Cancer
This study aims to evaluate the use of mobile technology as a communication tool among patients with breast cancer and measured its effect on patient-reported cancer-related distress, specifically focusing on young women as they…
- Trial name
- NCT07009093
- Testing
- Mighty Pro Application
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Wake Forest University Health Sciences
Thyroid Neoplasms, Neoplasm
EMDR Integrative Group Protocol and Individual Treatment for Patients With Cancer: A Pilot Study
The main aim of the present process-outcome study is to evaluate the feasibility and the effects of an EMDR-IGTP-OTS group intervention on a sample of people with cancer, by using a process-outcome study design, with repeated…
- Conditions
- Thyroid Neoplasms, Neoplasm, Post-traumatic Stress Disorder (PTSD), Psychological Distress
- Trial name
- NCT07447089
- Testing
- EMDR-IGTP-OTS
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- Università Cattolica di Milano