Clinical trials: Refractory Glaucoma
Glaucoma
Study of the Beacon Aqueous Microshunt in Patients With Refractory Glaucoma
This is a prospective, multicenter, single-arm clinical study to evaluate the safety and effectiveness of Beacon Aqueous Microshunt in patients with refractory glaucoma.
- Trial name
- Beacon (NCT04072016)
- Testing
- Beacon Aqueous Microshunt
- Where
- 4 sites in United States, Canada
- Volunteers
- 10 people
- Sponsor
- MicroOptx
Glaucoma, Trabeculectomy
Innovative Tube Trabeculectomy for Advanced and Refractory Glaucoma: A Randomized Controlled Trial
This study aims to compare the efficacy and safety of a novel surgical technique, Innovative Tube Trabeculectomy (ITT), against conventional trabeculectomy in patients with advanced and refractory glaucoma.
- Conditions
- Glaucoma, Trabeculectomy, Innovative Procedures
- Trial name
- ITT-RCT (NCT07755761)
- Testing
- Innovative Tube Trabeculectomy, Conventional Trabeculectomy
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Benha University
Glaucoma, Open-Angle
Early Evaluation of the Beacon Aqueous Microshunt in Patients Refractory to Drug Therapy in the European Union
This is prospective, non-randomized, single-arm study to assess the safety and effectiveness of lowering intraocular pressure with the Beacon Aqueous Microshunt. A total of 65 subjects will be enrolled at five centers.
- Trial name
- EARLY BIRD EU (NCT03634319)
- Testing
- Beacon Aqueous Microshunt
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- MicroOptx
Glaucoma, Intraocular Pressure
the Pops-titration Versus the Slow-coagulation Cyclophotocoagulation in Treatment of Refractory Glaucoma
Transcleral cyclophotocoagulation (TSCPC) has long been used as refractory glaucoma management and is very easy to learn and easy to perform.
- Trial name
- NCT01774227
- Testing
- The pops-titration group, The slow-coagulation group
- Where
- Thailand
- Volunteers
- 98 people
- Sponsor
- Prince of Songkla University
Treatment of Refractory Glaucoma
Comparison of Outcome and Effectiveness Between Micropulse Diode Laser Cyclophotocoagulation and Cyclocryoablation in Treatment of Refractory Glaucoma
laucoma having bad prognosis after maximally tolerated medication,glaucoma that fails after filtering operations, neovascular glaucoma, glaucoma following vitrectomy and glaucoma secondary to uveitis etc.
- Trial name
- NCT05437614
- Testing
- Micropulse diode laser cyclophotocoagulation in treatment of refractory Glaucoma, Cyclocryoablation in treatment of refractory Glaucoma
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- University of Health Sciences Lahore
Glaucoma, Blindness, Acquired
Laminar Drainage Implant: Safety of a Novel Surgical Treatment for Refractory Glaucoma.
Purpose: To assess the feasibility of a surgical technique and present the preliminary safety results of a new glaucoma device devoid of a tube in painful blind eyes.
- Conditions
- Glaucoma, Blindness, Acquired, End-Stage Glaucoma, Glaucoma Traumatic
- Trial name
- NCT03166566
- Testing
- Laminar drainage implant surgery.
- Volunteers
- 15 people
- Sponsor
- Federal University of Minas Gerais
Refractory Glaucoma
The Vizio Clinical Study
Evaluate the Safety and Efficacy of the Vizio Aqueous Microshunt for the Treatment of Refractory Glaucoma
- Trial name
- NCT06591117
- Testing
- Vizio Aqueous Microshunt
- Where
- El Salvador
- Volunteers
- 50 people
- Sponsor
- Ocumedex
Uveitis Related Cystoid Macular Edema, Steroid-induced Glaucoma - Borderline
The LIMO Study, Lucentis for Treatment of Uveitic Patients With Refractory Cystoid Macular Oedema
Anti-vascular endothelial growth factor (VEGF) treatments show great promise in the treatment of a variety of retinal diseases. This study addresses a condition which affects a large number of our patients in whom the…
- Trial name
- NCT01564108
- Testing
- Ranibizumab
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Moorfields Eye Hospital NHS Foundation Trust
Open Angle Glaucoma (OAG)
Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma
A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial
- Trial name
- NCT07220876
- Testing
- VisiPlate Glaucoma Implant
- Where
- 14 sites in United States, South Africa
- Volunteers
- 165 people
- Sponsor
- Avisi Technologies Inc.
Open Angle Glaucoma
Surgical Treatment of Refractory Open Angle Glaucoma
The primary objective of this study is to evaluate the safety, efficacy, and performance of the Suprachoroidal Dissection Instrument in creating a fistula between Schlemm's canal and the suprachoroidal space in refractory, open…
- Trial name
- NCT01212861
- Testing
- Suprachoroidal Dissection Instrument (SDI)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- iScience Interventional Corporation
Refractory Glaucoma
Real-world Evidence Study of XEN in Chinese Patients With Refractory Glaucoma
Real-world evidence study to assess the safety and effectiveness of XEN® Glaucoma Treatment System in Chinese patients with refractory glaucoma.
- Trial name
- NCT04303897
- Testing
- XEN Glaucoma Stent
- Where
- China
- Volunteers
- 59 people
- Sponsor
- Allergan
Glaucoma, Open-Angle, Glaucoma Secondary
The Outcome of Ahmed Glaucoma Valve in Difficult Glaucoma Cases
The clinical difference (mean IOP, success rate, and complications) on using S2 and FP7 models of Ahmed Glaucoma Valve that had similar dimensions and different materials used for their construction in one year follow up was…
- Conditions
- Glaucoma, Open-Angle, Glaucoma Secondary, Glaucoma, Neovascular
- Trial name
- NCT04214847
- Testing
- Ahmed Glaucoma Valve surgery
- Volunteers
- 1 people
- Sponsor
- Ain Shams University
Refractory Glaucoma
Comparison Between Two Techniques of Subthreshold Diode Laser Cyclophotocoagulation in Refractory Glaucoma
The aim of this study is to assess the results of subliminal subthreshold transscleral diode cyclophotocoagulation in refractory glaucoma using the standard technique of 360 degree application and to compare the outcome with a…
- Trial name
- NCT05230355
- Testing
- standard technique, modified pattern
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Assiut University
Glaucoma
A Prospective, Multicenter, Open-label, Safety and Preliminary Efficacy Study of the Surgical Implantation of OPKO's Glaucoma Drainage Device (AquashuntTM) in Patients With Refractory Chronic Forms of Open Angle Glaucoma (OAG)
A prospective, multicenter, open-label, safety and preliminary efficacy study of the surgical implantation of OPKO's glaucoma drainage device (AquashuntTM) in patients with refractory chronic forms of open angle glaucoma (OAG).
- Trial name
- NCT00834223
- Testing
- Aquashunt
- Where
- Dominican Republic
- Volunteers
- 15 people
- Sponsor
- OPKO Health, Inc.
Refractory Glaucoma
MicroPulse Transscleral Laser Cyclophotocoagulation With the Zig Zag Mode in Glaucoma.
This is a prospective single-arm clinical trial in which patients with neovascular or primary open angle glaucoma with uncontrolled intraocular pressure (despite maximal tolerated anti-glaucoma medical treatment) were selected…
- Trial name
- NCT05521334
- Testing
- micropulse transscleral cyclophotocoagulation
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Helwan University
Refractory Open Angle Glaucoma
Ocular Fluorophotometry for Glaucoma Treated With Cyclo-coagulation Using High Intensity Focused Ultrasound (HIFU).
Monocentric prospective study conducted in two phases evaluating the secretion and elimination of aqueous humor by fluorophotometry in patients with glaucoma treated with cyclo-coagulation with ultrasound.
- Trial name
- NCT01908985
- Testing
- high intensity focused ultrasound for cyclodestruction in the eye
- Sponsor
- EyeTechCare
Primary Open Angle Glaucoma (POAG)
Study of CyPass Implantation In Patients With Open Angle Glaucoma Refractory to Single or Multi-agent Topical Therapy
The purpose of this study is to evaluate the safety and effectiveness of CyPass implantation as a stand-alone therapy for lowering intraocular pressure (IOP) in patients with primary open angle glaucoma (POAG) who have failed at…
- Trial name
- DUETTE (NCT01166659)
- Testing
- CyPass Micro-Stent
- Volunteers
- 48 people
- Sponsor
- Transcend Medical, Inc.
Open-angle Glaucoma
Hydrus Microstent for Refractory Open-Angle Glaucoma
The purpose of this study is to assess the safety and effectiveness of the Hydrus Microstent in patients with refractory open-angle glaucoma.
- Trial name
- SUMMIT (NCT03267134)
- Testing
- Hydrus Microstent, Ophthalmic surgery
- Where
- 20 sites in United States, Colombia and 3 more
- Volunteers
- 217 people
- Sponsor
- Ivantis, Inc.
Advanced Glaucoma, Refractory Glaucoma
Safety Study of Conventional Versus Micropulse Transscleral Cyclophotocoagulation in Treating End-Stage Glaucoma
The aim of this study is to compare the safety and efficacy of conventional and micropulse transscleral diode laser in the treatment of end-stage glaucoma.
- Trial name
- NCT00349414
- Testing
- Micropulse Transscleral Cyclophotocoagulation, Conventional Transscleral Cyclophotocoagulation
- Where
- Singapore
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Glaucoma
Effect of Mitomycin-C on the Outcomes of Patients Receiving Ahmed Glaucoma Valve Implantation Surgery
The goal of this clinical trial is to determine if the intraoperative application of Mitomycin-C can enhance the outcomes of Ahmed Glaucoma Valve (AGV) implantation in treating refractory glaucoma.
- Trial name
- MMC (NCT06680245)
- Testing
- Mitomycin c
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton