Clinical trials: Refractive Surgery
Disorders, Refractive
A Comparison of Two Devices for Measuring the Central Thickness of the Cornea Before and After Surgery (CECOT)
Corneal topography allows the measure of the radii of curvature and of the thickness of the cornea. It is essential for diagnosis in ophthalmology and allows to highlight corneal irregularities such as a keratoconus, or too thin…
- Trial name
- CECOT (NCT02522416)
- Testing
- Central corneal thickness measurement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Operative Incision
70 vs 110 Degree Side-cut Angles in Femtosecond LASIK
The purpose of this study is to compare 70 and 110 degree side-cut angles on the same patient undergoing Femtosecond Laser-assisted in Situ Keratomileusis (FS-LASIK).
- Trial name
- NCT03122535
- Testing
- FS-LASIK 70 degree side-cut angle, FS-LASIK 110 degree side-cut angle
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Utah
Cataract Extraction, Phacoemulsification
A Study Comparing Two Monofocal, Aspheric, Hydrophobic Acrylic Intraocular Lenses: the Alcon CLAREON® and the Abbott Medical Optics PCB00
This is a bilateral randomised controlled study to compare visual performance, refractive outcome, forward light scatter, patient satisfaction and objective measurement of glistenings following insertion of two monofocal…
- Conditions
- Cataract Extraction, Phacoemulsification, Glistenings, Intraocular Lens Implant
- Trial name
- NCT03364972
- Testing
- Cataract surgery
- Where
- United Kingdom
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Traumatic Cataract
Long-term Visual and Refractive Outcomes After Traumatic Cataract Surgery in Children
This prospective multicenter observational study aims to evaluate long-term visual and ocular biometric outcomes in pediatric patients aged 0-16 years who were diagnosed with traumatic cataract and underwent cataract extraction…
- Trial name
- NCT07087275
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Jin Yang
Retinal Detachment, Lens Diseases
Retinal Detachment After Lens Surgery in the Nearsighted
This study aims to study the incidence of retinal detachment in the nearsighted myopic after phakoemulsification lens surgery and use of posterior chamber foldable soft implants with a follow-up of 5 years and preliminary results…
- Conditions
- Retinal Detachment, Lens Diseases, Short-Sighted
- Trial name
- A09F0401 (NCT04072939)
- Testing
- Patients having had a lens surgery
- Volunteers
- 101 people
- Sponsor
- University Hospital, Bordeaux
Image, Body
Whole Eye Optical Coherence Tomography (OCT) to Improve Refractive Surgery and Eye Care
The overall objective is to develop the hardware systems and software algorithms necessary to make accurate measurements of the whole eye with optical coherence tomography (OCT).
- Trial name
- NCT03219567
- Testing
- Optical Coherence Tomography (OCT), Magnetic resonance imaging (MRI)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Duke University
Ophthalmology, Photorefractive Keratectomy ("PRK")
Ocular Bandage Gel (OBG) Pivotal Trial in Patients Undergoing Photorefractive Keratectomy ("PRK")
Prospective, randomized, masked (reading center), controlled pivotal study of Ocular Bandage Gel (OBG) vs. a bandage contact lens (BCL) in subjects who have undergone bilateral photorefractive keratectomy (PRK).
- Conditions
- Ophthalmology, Photorefractive Keratectomy ("PRK"), Laser Assisted Surgery, Refractive Surgery
- Trial name
- NCT03938883
- Testing
- Ocular Bandage Gel (OBG), Bandage Contact Lens (BCL)
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Myopia, Astigmatism
An Outcomes Study Comparing the Intralase FS 60 to the Intralase iFS When Performing LASIK Surgery for Nearsightedness
The purpose of the study is to compare the results of LASIK surgery when using two versions of a femtosecond laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT01365728
- Testing
- LASIK with the iFS femtosecond laser
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Stanford University
Refractive Error
WaveLight® Refractive Myopic Study
The purpose of this study is to evaluate outcomes of subjects undergoing myopic surgery using the WaveLight® Refractive Suite (Excimer EX500 and Femtosecond FS200 lasers).
- Trial name
- NCT01941498
- Testing
- Wavelight® Refractive Suite, LASIK surgery
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Myopia, Small-incision Lenticule Extraction (SMILE) Surgery
Factor Analysis of Unintended Initial Dissection of the Posterior Plane
To explore the potential factors for unintended initial dissection of the posterior plane in a large sample retrospective analysis and surgeons of different levels.
- Trial name
- NCT05367154
- Testing
- Small incision lenticule extraction
- Where
- China
- Volunteers
- 3,003 people, healthy volunteers welcome
- Sponsor
- Yifeng Yu
Cataract
Outcomes of Clareon PanOptix Pro in Patients With Prior Myopic Refractive Surgery
This study is a Single center, single arm, prospective, observational study of clinical outcomes following bilateral cataract surgery and Clareon PanOptix Pro implantation.
- Trial name
- NCT06555289
- Testing
- Clareon PanOptix Pro IOL
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Juliette Eye Institute Research Center
Cataract, Astigmatism
Assessment of Visual and Refractive Results and Rotational Stability of the TECNIS® Eyhance Toric II 1-piece Posterior Chamber Lens in Patients With Astigmatism Undergoing Cataract Surgery
Cataract surgery is one of the most common procedures performed worldwide. Astigmatism is the most common refractive disorder in adults, hence there is a high prevalence of preexisting astigmatism in cataract patients.
- Trial name
- STATE (NCT05144308)
- Testing
- Images of the operated eye (s)
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pseudoexfoliation Syndrome, Cataract
Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome
This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome…
- Conditions
- Pseudoexfoliation Syndrome, Cataract, Astigmatism
- Trial name
- NCT07722247
- Testing
- phacoemulsification cataract surgery
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Pain After Photorefractive Keratectomy
The Role of Gabapentin in Postoperative Pain and Epithelialization After Photorefractive Keratectomy
The primary aims of this study are to determine if treatment with Gabapentin taken systemically (oral tablets) in patients who have photorefractive keratectomy (PRK) surgical treatments reduces post surgical neuropathic pain and…
- Trial name
- NCT01177514
- Testing
- Gabapentin, Sugar pill
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Codet Vision Institute
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Myopia, Astigmatism
A Study to Investigate the Safety and Effectiveness of Aspheric Laser Refractive Surgery Treatments for Myopia
The objective of this study was to compare the safety and effectiveness of two versions of the Bausch \& Lomb Zyoptix Tissue Saving Aspheric Algorithm versus the current Zyoptix Tissue Saving Algorithm when used for myopia and…
- Trial name
- NCT00365677
- Testing
- The Bausch & Lomb Zyoptix Tissue Saving Aspheric algorithm, The Bausch & Lomb Zyoptix Tissue Saving algorithm
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye Syndromes
Refractive Surgery and Optive Compatibility Study
To assess the compatibility of Optive with refractive surgery (PRK and LASIK) post-operatively.
- Trial name
- NCT00469157
- Testing
- Optive
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Innovative Medical
Astigmatism
Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET
The primary objective of this study is to evaluate rotational stability and functional improvements in visual acuity of the enVista monofocal Toric IOL (MX60ET) following cataract surgery.
- Trial name
- NCT05739656
- Testing
- CATARACT SURGERY
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bausch & Lomb Incorporated
Dry Eye Syndromes
TearLab Refractive Surgery Dry Eye Study
The primary objective of this study is to determine how pre \& post-operative tear osmolarity levels relate to rates of dry eye symptoms related to refractive surgery and if differences exist in patients who are pre-treated with…
- Trial name
- NCT01176045
- Where
- 8 sites in United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- TearLab Corporation
Astigmatism
A Study to Address Precision and Refractive Predictability of Femtosecond Laser-assisted Astigmatic Keratotomy Following the Cataract Surgery
The purpose of this open, prospective study is to address the effectiveness and precision of the VICTUS™ Femtosecond Laser Platform-assisted astigmatic keratotomy after femtolaser-assisted cataract surgery.
- Trial name
- NCT01752218
- Testing
- arcuate incision
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Technolas Perfect Vision GmbH