Clinical trials: Refractive Error - Myopia
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Presbyopia, Myopia
Intrastromal Correction of Ametropia by a Femtosecond Laser
This study evaluates the intrastromal correction of ametropia with a femtosecond laser made by 20/10 PERFECT VISION. This laser generates a beam of ultrashort, infrared pulses which enables very precise cuts in the cornea.
- Conditions
- Presbyopia, Myopia, Hyperopia, Astigmatism
- Trial name
- ISCAF (NCT00928122)
- Testing
- Intrastromal Correction of Presbyopia, Intrastromal correction of Myopia, Intrastromal Correction of Hyperopia
- Where
- 3 sites in Germany
- Volunteers
- 200 people
- Sponsor
- 20/10 Perfect Vision
Myopia
Wearing Behavior and Eye Length Changes in Children With Myopia Wearing Myopia Control Spectacle Lenses
The goal of this clinical trial is to learn how children with myopia aged 8 to 15 years move their eyes and heads during near-vision tasks while wearing different spectacle lenses, and if wearing myopia control spectacle lenses…
- Trial name
- NCT07780851
- Testing
- Single Vision Lens (SVL), Myopia Control Lens (MCL)
- Where
- Singapore
- Volunteers
- 20 people
- Sponsor
- Essilor International
Myopia
Atropine Eyedrops for Myopia Progression in Children and Adolescents (MODERATO STUDY)
Myopia, or shortsightedness, is a multifactorial disorder, governed by environmental and genetic factors. Myopia is the most common ocular disorder worldwide with an increasing prevalence over the past few decades and affecting…
- Trial name
- MODERATO (NCT07028827)
- Testing
- 0.05% atropine eye drops, 0.025% atropine eye drops
- Where
- 11 sites in Albania, Italy and 3 more
- Volunteers
- 234 people
- Sponsor
- Ocus Innovation Ireland Limited
Myopia
Comparison of Lens Fit and Lens Power of a New Contact Lens to Two Marketed Contact Lenses in a Population of Soft Contact Lens Wearers
The purpose of this study is to evaluate the comparability of lens fit and lens power of a new contact lens to the lens fit and lens power of two marketed lenses.
- Trial name
- NCT01244529
- Testing
- galy A Plus, seno A, galy A
- Where
- 2 sites in United Kingdom
- Volunteers
- 41 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Hyperopia
A Prospective Safety and Effectiveness Study of a New High Repetition Rate Excimer Laser Using LASIK for the Correction of Ammetropia and Presbyopia
This clinical study has been planned to evaluate the safety and effectiveness of common treatment algorithms using 500 Hz laser repetition rate for the correction of Ammetropia and Presbyopia
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- NCT02112968
- Testing
- Proscan, Zyoptix, Supracor
- Volunteers
- 97 people
- Sponsor
- Technolas Perfect Vision GmbH
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
Electronic Spectacles Versus Low Dose Atropine in Young Myopes
This is a bilateral, dispensing, masked, randomized clinical trial. Myopic children will be randomly assigned to one of the following: (1) Investigational clinical prototype (CP1) device without atropine, (2) Investigational CP1…
- Trial name
- NCT06034379
- Testing
- eSpectacle Clinical prototype (CP1) device, 0.01% atropine
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia
A Dispensing Comparison of a Test Daily 1 Day Lens Against a Control 1 Day Lens.
The purpose of this study is to compare the dispensing performance of somofilcon A test 1 day contact lens against somofilcon A control 1 day contact lens.
- Trial name
- NCT03951610
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 52 people
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study
The purpose of this study is to continuously assess the visual performance and safety of DAILIES TOTAL1 soft contact lenses in a real world setting and broader patient base through routine clinical practices.
- Conditions
- Myopia, Hyperopia, Presbyopia, Astigmatism
- Trial name
- NCT06483113
- Testing
- Delefilcon A spherical soft contact lenses, Delefilcon A toric soft contact lenses, Delefilcon A multifocal soft contact lenses
- Where
- 12 sites in United States
- Volunteers
- 192 people
- Sponsor
- Alcon Research
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Myopia, Hyperopia
Clinical Evaluation of Two Frequent Replacement Soft Spherical Contact Lenses
This was a single-blind (participant masked), interventional, prospective, direct refit, bilateral wear short-term fitting study.
- Trial name
- NCT05656885
- Testing
- Lens A, Lens B
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Safety and Tolerability Evaluation of PRO-230 Ophthalmic Solution
Phase I Study to evaluate safety and tolerability of PRO-230 (atropine sulphate 0.05%) ophthalmic solution through evaluation of incidence of non-expected adverse events (AE), photophobia, pupillary diameter, incidence of…
- Trial name
- PRO-230 (NCT05481489)
- Testing
- Atropine Sulfate
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Safety Study
A Safety Study of IVMED-85 Ophthalmic Solution in Healthy Adults
The purpose of this trial is to determine the safety of IVMED-85 eye drops in healthy adult subjects. Participants will be assigned to either the active or vehicle eyedrop group.
- Trial name
- NCT07370584
- Testing
- IVMED-85 ophthalmic solution, Vehicle Ophthalmic Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- iVeena Delivery Systems, Inc.
Myopia
Soft Lens Study: Biomedics 1 Day Extra Sphere and Clariti 1 Day Sphere
The aim of this study is to evaluate and compare the performance of two soft contact lenses.
- Trial name
- NCT06817785
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- CooperVision, Inc.
Myopia, Hyperopia
Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
The purpose of this study was to compare three CE-marked daily disposable contact lenses for tear film stability as measured by pre-lens non-invasive keratograph break up time (PL NIK-BUT).
- Conditions
- Myopia, Hyperopia, Refractive Error
- Trial name
- NCT01839318
- Testing
- Nelfilcon A contact lenses, Omafilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Myopia
Dispensing Study for a New Study Lens
This study investigated the performance criteria over one week of daily wear to determine if the comfilcon A asphere lens (test) performed equivalently to the comfilcon A sphere (control) in terms of measurement and subjective…
- Trial name
- NCT02642991
- Testing
- Phenacite, comfilcon A
- Where
- 3 sites in United States, Canada
- Volunteers
- 44 people
- Sponsor
- CooperVision, Inc.
Myopia
Pivotal Study of SAT-001 in Treatment of Pediatric Patient With Myopia
The objective of this clinical investigation is to evaluate the efficacy and safety of SAT-001 designed as Software as Medical Device (SaMD) for slowing myopia progression and treatment in pediatric myopia patients.
- Trial name
- NCT06344572
- Testing
- SAT-001, Single vision spectacles
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Myopia
A Study to Evaluate the Product Performance of the PureVision®2 High Definition (HD) Contact Lens
The objective of this study is to evaluate the product performance of PureVision2 HD contact lenses.
- Trial name
- NCT01416142
- Testing
- PureVision2 HD contact lenses, Spectacles
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Assessing the Performance of Lotrafilcon A Lenses During a Three Month Period
The purpose of this trial is to assess the performance of an investigational contact lens over a three month period.
- Trial name
- NCT00933166
- Testing
- Lotrafilcon A contact lens
- Volunteers
- 169 people
- Sponsor
- CIBA VISION