Clinical trials: Refractive Assessment
Myopia and Hyperopia and Presbyopia
Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens
The objective of this study is to evaluate the product performance of a new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens, when worn by…
- Trial name
- NCT05660577
- Testing
- new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens
- Where
- 20 sites in United States
- Volunteers
- 301 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Assessment of Progressive Lens Designs
Non-invasive double-blind randomised comparative study on presbyopic subjects wearing progressive lenses.
- Trial name
- TBPD (NCT04734522)
- Testing
- Progressive Additional Lenses (PAL), pre calibrated and made of polymeric material with anti-reflection coating
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Milano Bicocca
Cataract, Refractive Error
A Comparative Study of TECNIS Symfony Plus IOL and a Trifocal IOL
This is a multicenter, prospective, randomized, subject- and evaluator-masked, bilateral-implant study conducted at up to 15 sites worldwide.
- Trial name
- NCT04156737
- Testing
- TECNIS Symfony plus IOL Model ZHR00V, Trifocal Intraocular lens
- Where
- 5 sites in New Zealand, Philippines and 1 more
- Volunteers
- 205 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Astigmatism
Evaluation Study on Corneal Lens for Vision Correction
The objective of this study is to evaluate the fitting and visual outcomes of Nexis Lens, made of silicone commonly used in the contact lens industry, on healthy eye with or without astigmatism.
- Trial name
- NCT02053688
- Testing
- Astigmatic Correction Lens (Nexis ACCL lenses), Toric Soft Contact Lenses
- Where
- 6 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- FORSIGHT Vision3
Refractive Error
Clinical Investigation of Refraction Techniques
Prospective, multi-center, non-interventional, randomized, comparative clinical study to identify an optimal refractive technique that provides maximum plus refractive endpoint for best corrected distance visual acuity (BCDVA).
- Trial name
- NCT05461586
- Testing
- Refractive Technique (MR #1), Refractive Technique (MR #2)
- Where
- Australia
- Volunteers
- 35 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Presbyopia
Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes
The purpose of this study is to determine if the AcuFocus Corneal Inlay ACI 7000PDT will provide an effective method for the correction of presbyopia in patients who have normal distance vision but need a correction such as…
- Trial name
- ACI (NCT00850031)
- Testing
- AcuFocus Corneal Inlay
- Where
- 8 sites in Australia, Austria and 4 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Astigmatism
Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET
The primary objective of this study is to evaluate rotational stability and functional improvements in visual acuity of the enVista monofocal Toric IOL (MX60ET) following cataract surgery.
- Trial name
- NCT05739656
- Testing
- CATARACT SURGERY
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Hyperopia
Evaluation of Effectiveness of Correcting Refractive Error With Ready-made Spectacles
This research project will compare two methods of correcting refractive error (long or short-sightedness) with spectacle lenses.
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- RECS (NCT00657670)
- Testing
- Ready-made spectacles, Spectacles
- Where
- 2 sites in China, India
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-purpose Disinfecting Solution (MPDS) compared to AMO RevitaLens OcuTec® MPDS (US brand name)/COMPLETE RevitaLens (Europe brand name) in…
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684046
- Testing
- Opti-Free® PureMoist® MPDS, RevitaLens MPDS, Habitual Contact Lenses
- Volunteers
- 196 people
- Sponsor
- Alcon Research
Cataract, Myopia
Evaluation of Visual Acuity in Myopic Cataract Patients Using Trifocal Intraocular Lens
The PanOptix trifocal IOL is a new trifocal intraocular lens which is proved to provide good range of vision for distance, intermediate and near and good visual quality in cataract patients with normal axial length.
- Conditions
- Cataract, Myopia, Intraocular Lens
- Trial name
- NCT04927117
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Aier School of Ophthalmology, Central South University
Myopia
Evaluation of Conventional Photorefractive Keratectomy (PRK) in U.S. Army Personnel, Substudy of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel
The purpose of this study is to: 1. evaluate the safety and efficacy of conventional PRK in U.S. Army personnel who have naturally occurring myopia with or without astigmatism. 2.
- Trial name
- NCT00412568
- Testing
- Photorefractive Keratectomy (PRK)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Myopia, Astigmatism
Safety and Efficacy Evaluation of a New Contact Lens Disinfecting Solution in Soft Contact Lens Wearers
The purpose of this study is demonstrate substantial equivalence of an investigational contact lens disinfecting solution to a commercially available contact lens solution in silicone hydrogel and soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Hyperopia, Refractive Error
- Trial name
- NCT01912768
- Testing
- FID 120947A contact lens disinfecting solution, renu fresh multi-purpose solution, Soft contact lenses
- Volunteers
- 362 people
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
ClarVista HARMONI Toric Trial With Intraoperative Exchange
The purpose of this study was to demonstrate the safety and effectiveness of the HARMONI® Modular Intraocular Lens System with a toric optic in subjects with pre-existing corneal astigmatism in need of cataract surgery.
- Conditions
- Cataract, Corneal Astigmatism, Aphakia
- Trial name
- NCT03054649
- Testing
- HARMONI® Modular Intraocular Lens System, Intraoperative optic exchange
- Where
- 2 sites in Mexico, Philippines
- Volunteers
- 44 people
- Sponsor
- ClarVista Medical
Visual Acuity, Refractive Errors
Pre-symptomatic Screening of Visual Acuity in Pre-school Students
The present research process is a prospective, non-interventional clinical study that will be conducted -under the auspices of the Democritus University of Thrace (DUTH)- in the pre-school students of the city of Alexandroupolis…
- Conditions
- Visual Acuity, Refractive Errors, Low Vision, Vision Disorders
- Trial name
- NCT05835193
- Testing
- Diagnostic Test: Distance Visual Acuity Examination
- Where
- Greece
- Volunteers
- 1,098 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Choroidal Neovascularization, Myopia, Degenerative
Safety and Efficacy Study of Combretastatin A4 Phosphate to Treat Patients With Choroidal Neovascularization Secondary to Pathologic Myopia
The objectives of this study are to evaluate the safety and efficacy of 3 dose groups (27, 36 and 45 mg/m2) of Combretastatin A-4 Phosphate for the treatment of subfoveal choroidal neovascularization in subjects with pathologic…
- Trial name
- NCT01423149
- Testing
- Combretastatin A-4 Phosphate
- Volunteers
- 23 people
- Sponsor
- Mateon Therapeutics
Myopia
VEP for Assessment SMILE Visual Quality
To evaluate the subjective and objective postoperative visual quality employing pattern visual evoked potential (P-VEP) following small incision lenticule extraction (SMILE).
- Trial name
- SMILE VEP (NCT07889752)
- Testing
- small incision lenticule extraction (SMILE)
- Where
- China
- Volunteers
- 84 people
- Sponsor
- yuhao shao
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Cataract Extraction, Corneal Astigmatism
Assessment of Visual Performance in Patients With Low Levels of Astigmatism
To assess visual performance in patients with low levels (0.5-0.75 Diopters) of corneal astigmatism.
- Trial name
- NCT00842231
- Testing
- Visual performance measures
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Refractive Errors, Self-Examination
Comparison of a Smartphone Based Self Refraction Tool With Conventional Refraction Error Estimation Methods
Self evaluating tools based on smartphone devices are public available on the market for each person. The tools are used to estimate the existing refractive error for each eye of a patient. Hereafter, e.g.
- Trial name
- NCT03419351
- Testing
- Smartphone, Autorefractor, Individual
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen