Clinical trials: Refraction Error, open to volunteers
Myopia: Refractive Error
Evaluation of Novel Spectacles Intended for Myopia Management in a Short-Term Study
The primary objective of this study is to evaluate the visual acuity, wearability, and quality of vision with two novel multifocal glasses designs in habitual myopia control glasses wearers, in a non-dispensing study after…
- Trial name
- NCT07497672
- Testing
- Habitual myopia glasses, Myopia Glasses A, Myopia Glasses B
- Volunteers
- 20 people
- Sponsor
- Myoptechs, Inc
Astigmatism
Observational Study - TA- 2025-1
This multi-centric, prospective observational study collects biometric datasets as well as associated video recordings of the surgical procedure.
- Trial name
- TA OS 2025-1 (NCT07007897)
- Testing
- Optical Biometry, Cataract Surgery
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Haag-Streit AG
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Presbyopia Correction, Astigmatism
A Planned Study at Multiple Sites is Being Done to Compare the Results of Two Types of Trifocal Toric Intraocular Lenses Used in Cataract Surgery
To evaluate the clinical outcomes and patient satisfaction of two commercially available trifocal toric intraocular lenses Primary Objective: To compare the distance-corrected intermediate visual acuity between the two trifocal…
- Conditions
- Presbyopia Correction, Astigmatism, Cataract
- Trial name
- NCT07232615
- Testing
- Optiflex TRIO Intraocular Lens, AcrySof® IQ PanOptix®
- Where
- 6 sites in Germany, India and 1 more
- Volunteers
- 138 people
- Sponsor
- Biotech Healthcare Holding Gmbh
Aphakia, Astigmatism
Clareon TruPlus Study
The purpose of this research study is to generate safety and performance data for Clareon TruPlus Monofocal Intraocular Lenses (IOLs).
- Trial name
- NCT07502456
- Testing
- Clareon TruPlus Monofocal Non-Toric IOL, Clareon TruPlus Monofocal Toric IOL, Phacoemulsification
- Where
- 5 sites in United States
- Volunteers
- 185 people
- Sponsor
- Alcon Research
Myopia
Post-market Follow Up Study on Paragon CRT® 100 (Paflufocon D)
The main objective of this post market clinical study is to evaluate the effectiveness and safety of the Paragon CRT®100 Contact Lens.
- Trial name
- NCT04187599
- Testing
- Paragon CRT®100 Contact Lens
- Where
- 4 sites in China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients
A multicenter, randomized, double-Blind, crossover, placebo-controlled Phase II clinical Study to evaluate the efficacy and safety of BRIMOCHOL PF and CARBACHOL PF in the treatment of Chinese patients with presbyopia.
- Trial name
- NCT06948357
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Astigmatism, Myopia
Evaluation of Two Monthly Silicone Hydrogel Multifocal Toric in Soft Contact Lens Wearers
To compare the performance of two leading soft multifocal Toric contact lenses.
- Trial name
- NCT07829419
- Testing
- Lens A ( comfilcon A), Lens B ( lehfilcon A)
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Astigmatism
Clinical Performance and Outcomes After Toric Lens Transition
To evaluate subjective and clinical outcomes after transitioning from one toric soft contact lens to another over a one-month period.
- Trial name
- NCT07898995
- Testing
- Fanfilcon A Toric Contact Lens
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision International Limited (CVIL)
Cataract, Presbyopia
IC-8 Apthera IOL New Enrollment Post Approval Study
The purpose of this study is to verify the post-market safety of the IC-8 Apthera IOL after the treatment of posterior capsular opacification (PCO), an expected complication related to IC-8 Apthera IOL implantation.
- Conditions
- Cataract, Presbyopia, Posterior Capsule Opacification
- Trial name
- NCT06060041
- Where
- 14 sites in United States
- Volunteers
- 435 people
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism, Myopia
Effect of a Myopia Control Lens on the Astigmatism in Children
The goal of this clinical trial is to investigate over a one-year period the effect of myopia control spectacle lenses on astigmatism in children aged 6 to 13 years with myopia and astigmatism.
- Trial name
- MAC (NCT07810725)
- Testing
- Lenslet-based myopia control spectacle lens
- Volunteers
- 15 people
- Sponsor
- Essilor International
Myopia
Development of a New Device and Method to Assess the Degree of Myopia and/or Astigmatism in Myopic People
The purpose of this clinical investigation is to check whether the new device can correctly measure a person's degree of myopia and astigmatism.
- Trial name
- MDSW_DiVA2Rx (NCT07297810)
- Testing
- Optical correction values obtained with investigational device and visual acuity, Optical correction values obtained with an autorefractometer and visual acuity, Optical correction values obtained with a phoropter and visual acuity
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopia, Moderate
Software Refraction With Mobilerone Versus Retinoscopy
Software refraction in the mobilerone for myopia and astigmatism is a novel medical device for myopia adults and elder children with or without astigmatism.
- Conditions
- Myopia, Myopia, Moderate, Astigmatism
- Trial name
- SRMR (NCT06059521)
- Testing
- Software refraction with Eye Test Technology in a mobilerone, Retinoscopy
- Where
- 3 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
Pivotal Study of SAT-001 in Treatment of Pediatric Patient With Myopia
The objective of this clinical investigation is to evaluate the efficacy and safety of SAT-001 designed as Software as Medical Device (SaMD) for slowing myopia progression and treatment in pediatric myopia patients.
- Trial name
- NCT06344572
- Testing
- SAT-001, Single vision spectacles
- Where
- South Korea
- Volunteers
- 110 people
- Sponsor
- S-Alpha Therapeutics, Inc.
Myopia
Assessment of the Efficacy and Safety of a DYnaMic Peripheral DegradatiON Myopia Disorder Control in Myopic Children ״DYMOND Study״
The DYMOND study evaluates the safety and effectiveness of TrackSight™, a digital medical application designed to slow myopia (nearsightedness) progression in children during everyday screen use.
- Trial name
- DYMOND (NCT07390500)
- Testing
- TrackSight
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- NovaSight
Presbyopia
Open Label, Multi-center, Phase I Study of TECLens Quantitative Refractive Crosslinking in Presbyopia-Aged Patients.
An 'on-eye' UV delivery system for corneal crosslinking can be used safely and effectively to help free presbyopic patients from the need for reading glasses.
- Trial name
- NCT07208604
- Testing
- Quantitative refractive crosslinking
- Where
- Philippines
- Volunteers
- 25 people
- Sponsor
- TECLens, Inc.
Ametropia, Myopia; Refractive Error
The Objective of This Study is to Evaluate the Perfomance of a Photorefraction Device for Screening Ametropia in Children. Eligible Participants Will Undergo Multiple Refractive Error Measurements, Visual Acuity and Strabismus Assessments During a Single Evaluation Visit.
The goal of this clinical trial is to evaluate the performance of a photorefraction screener in terms of sensibility, sensitivity and accuracy on children aged 3 to 8 y.o.
- Conditions
- Ametropia, Myopia; Refractive Error, Myopia; Astigmatism
- Trial name
- NCT06882408
- Testing
- Photorefraction device under investigation, Comparator device, Tabletop auto-refractometer, Comparator device, portable photorefraction device
- Where
- 2 sites in France
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
A Phase 3 Clinical Study of QLM3004 in Delaying Myopia in Children
Efficacy and Safety Study of QLM3004 in Myopic Children
- Trial name
- NCT06151587
- Testing
- QLM3004 Concentration 1, QLM3004 Concentration 2, QLM3004 Concentration 3
- Where
- China
- Volunteers
- 735 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Myopia, Child Myopia Progression
Effect of MiYOSMART iQ Spectacle Lenses on Myopia Progression in Children
This prospective, single-center study aims to evaluate the efficacy and safety of MiYOSMART iQ spectacle lenses with DIMS (Defocus Incorporated Multiple Segments) and Triple Enhanced Design (TED) technology in slowing myopia…
- Trial name
- NCT07387159
- Testing
- MiYOSMART iQ spectacle lenses
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- Hoya Lens Rus LLC