Clinical trials: Recurrent Pancreatitis
Resectable Pancreatic Head Neoplasm, Resectable Periampullary Neoplasm
Economisation of Whipple Resection Using an Ultrasonic Dissection Device
Including 150 randomised patient, the studies aim is to determine whether an economisation and/or improvement in terms of operating time, drainage fluid, blood loss, time of hospitalisation can be found using an ultrasonic…
- Conditions
- Resectable Pancreatic Head Neoplasm, Resectable Periampullary Neoplasm, Chronic Pancreatitis
- Trial name
- NCT01321450
- Where
- 3 sites in Germany, Greece and 1 more
- Volunteers
- 82 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Chronic Pancreatitis, Pancreatic Cancer
Prospective Study of Celiac Block Injection: 1 vs. 2
The purpose of this prospective randomized study is to compare the clinical effectiveness of EUS-guided CB performed with a single injection versus two injections of medication into the celiac ganglion region.
- Trial name
- NCT00583479
- Testing
- one injection into the celiac ganglion, two injections into the celiac ganglion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Indiana University
Pancreatitis, Chronic
Feasibility of a Mobile Electronic Mindfulness Therapy Service for Chronic Pancreatitis
The research objective of this pilot study is to test the feasibility of a mobile electronic mindfulness therapy service for patients with definite or suspected chronic pancreatitis.
- Trial name
- NCT02224898
- Testing
- Mobile Mindfulness Therapy
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Stanford University
Acute Pancreatitis, Recurrent Acute Pancreatitis
Preventing the Recurrence of Acute Pancreatitis by Alcohol and Smoking Cessation
Recurrence of acute pancreatitis (AP) is often facilitated by regular alcohol consumption and smoking. An applied lifestyle intervention focusing on the cessation of alcohol consumption and smoking might prevent the recurrence of…
- Trial name
- REAPPEAR (NCT04647097)
- Testing
- Standard intervention only, Standard intervention plus repeated intervention
- Where
- Hungary
- Volunteers
- 364 people
- Sponsor
- University of Pecs
Pancreatic Cancer, Diabetes
Artificial Intelligence-based Early Screening of Pancreatic Cancer and High Risk Tracing (ESPRIT-AI)
Pancreatic cancer is one of the most fatal malignancies with a 5-year survival rate of only ~6%[1]. The reasons for this high mortality rate can be attributed to several factors, of which perhaps the most important is delayed…
- Conditions
- Pancreatic Cancer, Diabetes, Familial Pancreatic Cancer, Pancreatic Cystic Neoplasm
- Trial name
- ESPRIT-AI (NCT04743479)
- Testing
- high-resolution MRI/CT examinations
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Feasibility Study of a Mobile Health App for Symptom Monitoring in People With Chronic Pancreatitis
Patients with chronic pancreatitis suffer from constant debilitating symptoms. They have complex needs and require specialist, multi-disciplinary care.
- Trial name
- SmartCP (NCT05899335)
- Testing
- SmartCP (mobile phone app)
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- University of Dublin, Trinity College
SIBO, Pancreatic Insufficiency
Breath Test-Based Assessment of SIBO in Chronic Pancreatitis and Partial Pancreatectomy
Pancreatic exocrine insufficiency (PEI) results from reduced pancreatic enzyme secretion, leading to malabsorption, malnutrition, and impaired quality of life.
- Conditions
- SIBO, Pancreatic Insufficiency, Chronic Pancreatitis, Pancreatic Surgey
- Trial name
- DCP-PCT-EPI (NCT07479238)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pancreatic Cancer, IPMN, Pancreatic
Pancreatic Cancer Initial Detection Via Liquid Biopsy
The overall rationale of PANCAID is to provide a diagnostic blood test for early diagnosis of pancreatic cancer. With a set of different liquid biopsy methods, it is the aim to measure these markers in well-defined patient…
- Conditions
- Pancreatic Cancer, IPMN, Pancreatic, Individuals at Risk, Chronic Pancreatitis
- Trial name
- PANCAID (NCT06283576)
- Testing
- Liquid biopsy
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Chronic Pancreatitis
A Tailored, Web-Based Self-Management Program to Treat Pain in Chronic Pancreatitis
This research study aims to evaluate the feasibility and acceptability of a web-based, self-guided, disease-specific self-management program tailored to individual health status profiles for patients with painful chronic…
- Trial name
- NCT07223554
- Testing
- Web-based self--management program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Michigan
Chronic Pancreatitis
Assessing the Utility of Cognitive Behavioral Therapy for Pain Control in Patients With Chronic Pancreatitis
This study will assess cognitive behavioral therapy as an adjunct to conventional symptom control for patients with chronic pancreatitis.
- Trial name
- NCT03112759
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Louisville
Pancreatitis, Chronic, Pancreatic Duct Stone
Comparison of Efficacy of ESWL and Laser Lithotripsy in Chronic Pancreatitis With ERCP
This study will compare the efficacy of ESWL and Laser Lithotripsy in the treatment of pancreatic duct stones with ERCP.
- Trial name
- NCT05326542
- Testing
- ESWL and ERCP, LL and ERCP
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Nerve Growth Factor in Chronic Pancreatitis
This study is to understand the role of nerve growth factor(NGF) and other cytokines in the pancreatic fluid of patients with chronic pancreatitis. Hypothesis: 1.
- Trial name
- NCT01255917
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Virginia Commonwealth University
Chronic Pancreatitis, Exocrine Pancreas Carcinoma
Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study
This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer.
- Conditions
- Chronic Pancreatitis, Exocrine Pancreas Carcinoma, Recurrent Acute Pancreatitis
- Trial name
- NCT06651580
- Testing
- Biospecimen Collection, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 26 sites in United States, Australia and 2 more
- Volunteers
- 1,600 people
- Sponsor
- M.D. Anderson Cancer Center
Pancreas Cancer, Pancreatitis
Pancreas Registry and High Risk Registry
The purpose of this study is to establish a registry of patients with pancreatic diseases. Patients included in the registry may include those with: pancreatic cancer, precancerous lesions of the pancreas, inflammatory lesions of…
- Conditions
- Pancreas Cancer, Pancreatitis, Chronic Pancreatitis, Pancreatic Cyst
- Trial name
- NCT02775461
- Where
- 2 sites in United States
- Volunteers
- 1,368 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Chronic Pancreatitis, Pain
Effect of Non-enteric Coated Enzymes Substitution on Pain in Patients With Chronic Pancreatitis
Pain in CP entails several independent yet overlapping mechanisms including oxidative stress-mediated parenchymal inflammation, pancreatic and central neuropathy and neuroplasticity.
- Trial name
- NE-PERT (NCT05042284)
- Testing
- Non-enteric coated pancreatic enzyme preparation
- Where
- India
- Volunteers
- 107 people
- Sponsor
- Asian Institute of Gastroenterology, India
Chronic Pancreatitis
Translation and Validation of Chinese COMPAT-SF
The goal of this observational study is to translate, adapt, and test the reliability of a Chinese version of the Comprehensive Pain Assessment Tool Short Form (COMPAT-SF) for people with chronic pancreatitis.
- Trial name
- COMPAT-SF-CV (NCT06917716)
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Predictive Biomarker for Endoscopic Therapy in Chronic Pancreatitis
This is an observational prospective study to develop predictive biomarkers for pain response in participants with chronic pancreatitis scheduled for endoscopic therapy.
- Trial name
- NCT06267365
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- NYU Langone Health
Safety Issues, Pain
Role of a CCK Receptor Antagonist Proglumide in Management of Chronic Pancreatitis
Chronic pancreatitis is a rare but debilitating condition associated with chronic abdominal pain, diarrhea, diabetes, and an 8-fold increased risk for the development of pancreatic cancer.
- Conditions
- Safety Issues, Pain, Pancreas Fibrosis
- Trial name
- ProCP (NCT05551858)
- Testing
- Proglumide
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Georgetown University
Cohort Study, Recurrent Acute Pancreatitis
Natural Course and Therapeutic Effect of Recurrent Acute Pancreatitis
The goal of this observational cohort study is to learn about the etiology, natural course, therapeutic effect and outcome of recurrent acute pancreatitis patients.
- Trial name
- NACRE (NCT06355206)
- Testing
- endoscopic intervention, surgery or conservative treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Changhai Hospital
Chronic Pancreatitis
Study on Predictive Factors, Safety and Efficacy of Endoscopic Retrograde Accessory Pancreatography in CP
Chronic pancreatitis (CP) can manifest characteristic pathological modifications such as pancreatic duct stenosis and pancreatic duct lithiasis.
- Trial name
- NCT06684301
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Changhai Hospital