Clinical trials: Rectocele
Pelvic Organ Prolapse Vaginal Surgery, Pelvic Organ Prolapse (POP)
Effectiveness of Perineorrhaphy in Pelvic Organ Prolapse Surgery
This is an observational registry-based study of long-term outcome after vaginal native tissue repair for pelvic organ prolapse designed to emulate a pragmatic open-label two-arm trial for which patients, in whom perineorrhaphy…
- Trial name
- PINPOPS (NCT07006129)
- Testing
- Perineorrhaphy, No perineorrhaphy
- Where
- Sweden
- Volunteers
- 40,646 people
- Sponsor
- Lund University
Rectal Prolapse, Fecal Incontinence
Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy
Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that…
- Conditions
- Rectal Prolapse, Fecal Incontinence, Defecation Disorder, Enterocele
- Trial name
- NCT06330857
- Testing
- Laparoscopic vaginorectopexy
- Volunteers
- 25 people
- Sponsor
- Sahlgrenska University Hospital
Obstructive Defecation Syndrome, Chronic Constipation
Laparoscopic Ventral Mesh Rectopexy Combined With or Without Stapled Trans-anal Rectal Resection for Obstructed Defecation Syndrome
Obstructed defecation syndrome (ODS) is a common problem in women. Rectal prolapse and rectocoele are frequently identified in patients with ODS.
- Conditions
- Obstructive Defecation Syndrome, Chronic Constipation, Rectal Prolapse
- Trial name
- NCT03060330
- Testing
- Modified Laparoscopic Ventral Mesh Rectopexy, Modified Laparoscopic Ventral Mesh Rectopexy Combined with Stapled Trans-anal Rectal Resection
- Where
- China
- Volunteers
- 126 people
- Sponsor
- Renmin Hospital of Wuhan University
Rectocele; Female, Pelvic Organ Prolapse
Gamma-irradiated Amniotic Membrane Graft in Posterior Colporrhaphy
The goal of this clinical trial is to test the benefit of using gamma-irradiated amniotic membrane as a graft in surgical repair for women with posterior vaginal wall defects.
- Trial name
- NCT06117670
- Testing
- posterior colporrhaphy using gamma-irradiated amniotic membrane as a graft
- Where
- Egypt
- Volunteers
- 25 people
- Sponsor
- Ain Shams Maternity Hospital
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Pelvic Organ Prolapse
Restorelle® Mesh Versus Native Tissue Repair for Prolapse
The purpose of this study is to collect information on the safety and effectiveness of Restorelle Direct Fix mesh and the surgical procedure to implant Restorelle.
- Trial name
- NCT02162615
- Testing
- Restorelle Direct Fix A, Restorelle Direct Fix P, Native Tissue Repair Anterior
- Where
- 49 sites in United States, Australia and 4 more
- Volunteers
- 810 people
- Sponsor
- Coloplast A/S
Uterine Prolapse, Bladder Diseases
Pelvic Floor Muscle Training (PFMT) in Treatment and Prevention of POP (POP Study)
Background: The pelvic floor muscles (PFM) are located inside the pelvis, surrounding the urethra, vagina and rectum. They provide structural support for the pelvic organs.
- Conditions
- Uterine Prolapse, Bladder Diseases, Cystocele, Rectocele
- Trial name
- NCT00271297
- Testing
- Pelvic floor muscle training
- Where
- Norway
- Volunteers
- 168 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Rectocele; Female
Transanal vs Transvaginal Rectal Resection for Anterior Rectocele
Female patients presenting with obstructed defecation syndrome due to anterior rectocele will be screened according to inclusion and exclusion criteria.
- Trial name
- NCT07375147
- Testing
- Stapled Transanal Rectal Resection, Stapled Transvaginal Rectal Resection
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Cairo University
Rectocele, Pelvic Organ Prolapse
An Intervention to Improve Prolapse Using Femmeze® (v1)
The main purpose of the feasibility study is to identify the patient experience of Femmeze® which is a device aimed at improving posterior vaginal compartment prolapse (rectocele) for women with obstructive defaecation.
- Trial name
- Femmeze® (NCT02280382)
- Testing
- Femmeze®
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Rectocele
Trans-perineal Repair With or Without Limited Internal Sphincterotomy for Treatment of Type I Anterior Rectocele
Comparison between transperineal repair of rectocele with or without posterior internal sphincterotomy.
- Trial name
- NCT02659176
- Testing
- Transperineal repair with PIS, Transperineal repair without PIS
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Pelvic Organ Prolapse, Rectocele
Impact of Defecation Posture on Ease of Bowel Movements in Patients With a Rectocele
The study aims to determine if defecation posture, when using a defecation posture modification device (DPMD), will improve ease of bowel movements in patients with pelvic organ prolapse, specifically rectoceles.
- Conditions
- Pelvic Organ Prolapse, Rectocele, Bowel Dysfunction
- Trial name
- NCT06252714
- Testing
- Defecation Posture Modification Device
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- TriHealth Inc.
Pelvic Organ Prolapse, Cystocele
SCP vs HUSLS for Pelvic Organ Prolapse Repair
The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse, Cystocele, Rectocele, Enterocele
- Trial name
- NCT02800512
- Testing
- Robotic sacrocolpopexy, high uterosacral ligament suspension
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Loma Linda University
Rectal Prolapse, Defecation Disorder
Rectal Prolapse With ODS. STARR vs LVR.
The objective of the study will be to evaluate the clinical and functional outcome of patients with obstructed defecation sndrome (ODS) associated to internal rectal prolapse, treated with transanal prolassectomy (STARR) surgery…
- Conditions
- Rectal Prolapse, Defecation Disorder, Rectocele; Female, Surgery
- Trial name
- NCT04892108
- Testing
- STARR (Stapled Trans Anal Rectal Resection), LVR (Laparoscopic Ventral Rectopexy)
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- University Hospital of Ferrara
Rectocele, Pelvic Organ Prolapse
Fat Injection for Rectocele Treatment: A Novel Approach
This clinical trial aims to evaluate the effectiveness of autologous fat grafting as a novel treatment for rectocele, a condition characterized by the herniation of rectal tissue into the posterior vaginal wall.
- Conditions
- Rectocele, Pelvic Organ Prolapse, Obstructive Defecation Syndrome
- Trial name
- NCT06604702
- Testing
- Autologous Fat Injection for Rectocele
- Volunteers
- 25 people
- Sponsor
- Cairo University
Rectocele; Female
Long-term Results of the Stapled Transanal Rectal Resection (STARR) Operation Proposed in the Treatment of a Rectocele
Rectal static disorders, including the rectocele, represent a frequent functional pathology which affects the quality of life of affected patients.
- Trial name
- STARRLOC (NCT05037422)
- Testing
- STARR surgery
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Grenoble
Sensation of Inadequate Defecation, Rectal Prolapse
Surgical Treatment of Obstructed Defecation Syndrome
Obstructed Defecation is a profoundly disabling condition. Many different surgical procedures has been introduced to treat patients affected by this disease. The most used are STARR and ventral rectopexy.
- Conditions
- Sensation of Inadequate Defecation, Rectal Prolapse, Rectocele
- Trial name
- PRO-REST (NCT01899209)
- Testing
- STARR, Laparoscopic Ventral Rectopexy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pelvic Floor Prolapse, Functional Constipation
Efficacy of Conservative Treatment of Functional Defecatory Disorders in Females With Pelvic Organ Prolapse
This study is planned to evaluate the efficacy of complex conservative treatment (including tibial neuromodulation, biofeedback therapy, special pelvic floor training and diet modification) in women with pelvic organ prolapse
- Conditions
- Pelvic Floor Prolapse, Functional Constipation, Rectocele
- Trial name
- NCT04547816
- Testing
- Biofeedback therapy, Tibial neuromodulation, Pelvic floor muscles training
- Where
- 2 sites in Russia
- Volunteers
- 100 people
- Sponsor
- Federal State Budgetary Scientific Institution
Pelvic Organ Prolapse, Uterine Prolapse
Does a High BMI Affect Supervised Pelvic Floor Muscle Training for Improving Symptoms in Women With Various Stages of Pelvic Organ Prolapse?
The trial design is a quasi-experimental cohort trial that includes women referred for pelvic organ prolapse specific physiotherapy.
- Conditions
- Pelvic Organ Prolapse, Uterine Prolapse, Anterior Wall; Prolapse, Vaginal, Posterior Wall; Prolapse, Vaginal
- Trial name
- NCT04009694
- Testing
- Pelvic Floor Muscle training
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Salford
Urinary Incontinence, Cystocele
Enhanced Recovery Protocol in Urogynecologic Surgery
Enhanced recovery after surgery (ERAS) has been shown to improve postoperative outcomes in a variety of surgical conditions. However, data regarding its role in urogynecologic surgery is limited.
- Conditions
- Urinary Incontinence, Cystocele, Rectocele, Pelvic Organ Prolapse
- Trial name
- NCT04175782
- Testing
- Enhanced recovery after surgery (ERAS) protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Rectocele, Perineal Descent
Transverse Perineal Support With STARR for Anterior Rectocele With Excessive Perineal Descent
This prospective randomized controlled trial will include adult patients with ODS, anterior rectocele ≥3 cm, and excessive perineal descent following failure of conservative treatment.
- Trial name
- NCT07777146
- Testing
- STARR Procedure, STARR combined with transverse perineal support procedure
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Cairo University