Clinical trials: Rectal Bleeding
Hemorrhoid, Internal Hemorrhoids
Prospective HemorrhoIdaL EmboliSation (PILES) Registry
The goal of this observational study (prospective registry) is to collect long-term real-world data on the effectiveness and safety of hemorrhoid artery embolization (HAE) for symptomatic bleeding internal hemorrhoids in adults…
- Conditions
- Hemorrhoid, Internal Hemorrhoids, Hemorrhoid Bleeding, Hemorrhoidal Bleeding
- Trial name
- PILES (NCT07635784)
- Testing
- Hemorrhoid Artery Embolization
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- Joint & Vascular Institute
Gastrointestinal Hemorrhage
The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin
The risk of bleeding after polypectomy of large colorectal polyps in patients taking aspirin is uncertain. This is a randomized, multi-center, placebo-controlled, double-blind study to compare the risk of significant bleeding…
- Trial name
- ASAPOL (NCT01549418)
- Testing
- Aspirin (ASA)
- Volunteers
- 760 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to
ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS AFTER LAPAROSCOPIC SURGERY FOR COLORECTAL CANCER.
Overall, only limited evidence exists regarding the clinical benefit of antithrombotic prophylaxis after laparoscopic surgery for cancer.
- Conditions
- The Primary Study Objective is to Assess the Efficacy and, Safety of Extended 4-week Heparin Prophylaxis Compared to, Prophylaxis Given for 8±2 Days After Planned Laparoscopic, Surgery for Colorectal Cancer.
- Trial name
- PRO-LAPS I (NCT01589146)
- Testing
- Heparin, Low-Molecular-Weight
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- University Of Perugia
Haemorrhoidal Bleeding
ARTerial EMbolization for haemorrhoIdal Disease (ART.EM.I. Study)
Haemorrhoidal disease is amongst the most common rectal conditions causing significant distress to the affected patients. Current surgical techniques for the treatment of internal haemorrhoids are associated with several…
- Trial name
- ARTEMIS (NCT04684251)
- Testing
- Coil embolisation of hemorrhoidal arteries.
- Where
- United Kingdom
- Sponsor
- Oxford University Hospitals NHS Trust
Hemorrhoids Internal, Hemorrhoids Second Degree
Comparing Rectal Artery Embolization and Surgery for Treatment of Bleeding Grade 2 and 3 Internal Hemorrhoids
This Phase II study will compare rectal artery embolization with operative hemorrhoidectomy in adults with symptomatic bleeding grade 2 and 3 internal hemorrhoids.
- Conditions
- Hemorrhoids Internal, Hemorrhoids Second Degree, Hemorrhoids Third Degree
- Trial name
- HemEmbo (NCT07844629)
- Testing
- Rectal Artery Embolization, Operative Hemorrhoidectomy
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Colorado, Denver
Abdominal Pain, Inflammatory Bowel Diseases
Examining the Effect of Ondansetron on Bowel Prep Success
This is a pilot randomized-controlled trial assessing the utility of ondansetron for improving pediatric pre-colonoscopy bowel prep outcomes using the boston bowel preparation score, as well as assessing the impact on patient…
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Eosinophilic Gastroenteritis, Diarrhea
- Trial name
- NCT05439772
- Testing
- Ondansetron
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- State University of New York - Downstate Medical Center
Misoprostol, Blood Loss, Myomectomy
Rectal Misoprostol in Women Undergoing Myomectomy for Intraoperative Blood Loss: A Randomized Placebo-controlled Study
Comparison of efficacy of rectal misoprostol for reduction amount of blood loss in women undergoing myomectomy, both open and laparoscopic approach
- Trial name
- NCT02908295
- Testing
- Rectal Misoprostol
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Colorectal Carcinoma (CRC), Right Hemicolectomy
The Intraoperative Technical Errors of Robotic vs. Laparoscopic Radical Right Hemiclectomy
Experimental design: This study is a multicenter, prospective, randomized, controlled phase III clinical trial that identifies, classifies, defines, and quantitatively analyzes technical errors between robotic and laparoscopic…
- Trial name
- NCT07138859
- Testing
- Robot assisted radical right hemicolectomy (D3 lymph node dissection), Laparoscopic assisted radical right hemicolectomy (D3 lymph node dissection)
- Where
- China
- Volunteers
- 368 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Colo-rectal Cancer
Efficacy of a Hemostatic Agent (PuraStat®) in Reducing Delayed Bleeding After Endoscopic Submucosal Dissection
The problem of delayed bleeding after endoscopic resection is becoming important due to the growing number of indications for anti-aggregation or anticoagulant treatment for cardiovascular reasons in the aging populations.
- Trial name
- NCT05031325
- Testing
- Endoscopic submucosal dissection with Purastat
- Where
- France
- Volunteers
- 288 people
- Sponsor
- Mathieu Pioche
Diarrhea, Constipation
Epidemiological Study of Colorectal Cancer in WuHan
The incidence risk of colorectal cancer （CRC） is increasing at 4.2% year by year in China. Most effective way to reduce the death rate of CRC patients is to diagnose in quite an early stage.
- Conditions
- Diarrhea, Constipation, Melena, Neoplasm
- Trial name
- NCT01863303
- Volunteers
- 1 people
- Sponsor
- Wuhan Pu-Ai Hospital
Piles, Bleeding
Is Doppler Necessary in Haemorrhoidal Artery Ligation Operation?
Haemorrhoidal artery ligation operation (HALO) is an operation that ties off vessels to piles. This study examines whether the ultrasound (doppler) is necessary to guide this tying off or not.
- Trial name
- NCT01051180
- Testing
- HALO
- Where
- United Kingdom
- Volunteers
- 150 people
- Sponsor
- Poole Hospital NHS Foundation Trust
Colorectal Cancer, Colorectal Neoplasms
Fecal Immunochemical Test for Advanced Adenoma Detection in Colorectal Cancer Screening
Early detecting and removing of colorectal advanced adenomas can reduce incidence of colorectal cancer. In order to reduce the incidence of colorectal cancer, improve the early diagnosis of colorectal cancer, the investigators…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Colorectal Adenoma
- Trial name
- NCT05200611
- Testing
- Fecal Immunochemical Test
- Where
- 2 sites in China
- Volunteers
- 5,000 people
- Sponsor
- Shandong University
Anastomotic Leak, Anastomotic Haemorrhage
THREE-row Circular STAPLER in Low Anterior Resection for Rectal Cancer
This trial aims to assess safety and efficacy of three-row circular staplers compared to two-row surgical stapllers in short-term and long-term perspective in patients with rectal cancer undergoing low anterior resection with…
- Conditions
- Anastomotic Leak, Anastomotic Haemorrhage, Anastomotic Complication, Rectal Neoplasms
- Trial name
- THREESTAPLER (NCT03910699)
- Testing
- Three-row circular stapler, Two-row circular stapler
- Where
- Russia
- Volunteers
- 154 people
- Sponsor
- Russian Society of Colorectal Surgeons
Postpartum Hemorrhage
CARBETOCIN VERSUS RECTAL MISOPROSTOL FOR MANAGEMENT OF THIRD STAGE OF LABOR IN WOMEN AT LOW RISK OF POSTPARTUM HEMORRHAGE
150 pregnant women admitted for spontaneous, induced or augmented vaginal delivery and categorized as low risk for postpartum hemorrhage (PPH) were divided randomly into two groups.
- Trial name
- NCT03556852
- Testing
- Carbetocin, Misoprostol
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Cairo University
Bleeding Hemorrhoids, Rectal Evacuation Disorders
Rectal Evacuation Disorders and Straining-associated Symptoms in Bleeding Hemorrhoids
This study aims to understand the mechanisms of straining on anorectal testing, to better help people receive more effective treatment advice.
- Trial name
- NCT07161765
- Testing
- Anorectal manometry
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Colorectal Neoplasms, Colorectal Cancer
Effectiveness of an Integrated Colorectal Cancer Screening in Saudi Arabia: A Pragmatic Randomized Trial
The global burden of colorectal cancer (CRC) incidence among young age groups is rising and overwhelming. This new trend of young-onset CRC incidence is evident in western countries.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colonic Polyp, Occult Bleeding
- Trial name
- CRCScreen (NCT04875793)
- Testing
- Stool for Occult Blood Test and Colonoscopy with comprehensive medical checkups
- Where
- Saudi Arabia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Tabuk
Rectal Bleeding
Colonic Capsule Endoscopy (CCE) for Screening of Neoplasm's A Pilot Study
The primary aim is to evaluate the efficiency of capsule endoscopy (CCE) in in the detection of neoplasms compared to conventional colonoscopy in persons participating in the Danish screening program for colorectal cancer with a…
- Trial name
- NCT02303756
- Testing
- Pillcam® COLON Capsule
- Where
- Denmark
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hematochezia
Capsule Endoscopy for Severe Hematochezia
Patients with severe hematochezia (bright red blood per rectum) may have a bleeding source proximal to the colon. Visualization of the entire gastrointestinal tract using a second-generation colon capsule endoscopy system could…
- Trial name
- NCT03616041
- Testing
- Second-generation colon capsule endoscopy system
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- CURE Digestive Diseases Research Center
All Diagnosed Health Conditions, ADD/ADHD
At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions
We are the missing link in clinical trials, connecting patients and researchers seamlessly and conveniently using a mobile health platform to advance medical research.
- Conditions
- All Diagnosed Health Conditions, ADD/ADHD, Alopecia Areata, Ankylosing Spondylitis
- Trial name
- NCT01931644
- Where
- United States
- Volunteers
- 17,667 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Breast Milk Protein Intolerance
Recruiting All Strictly Breast-fed Babies With Blood In Stool
Breast feeding is the most nutritious form of nourishment in infants and is recommended for at least the first four months of life. Breast fed infants may develop milk protein intolerance.
- Trial name
- NCT02745977
- Testing
- Dairy Free Diet
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Winthrop University Hospital