Clinical trials: Recovery of Function
Maxillofacial Abnormalities
Evaluation of the Long-term Results of Extended Supra-basillary Genioplasty of the "Chin Wing" Type Without Bone Graft
The correction of maxillomandibular dysmorphoses, responsible for both functional discomfort (lip incompetence, ventilation disorders, periodontal disease) but also aesthetic, calls in particular for genioplasty, of which there…
- Trial name
- SASCWatch (NCT06183853)
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Strasbourg, France
Oliceridine Fumarate
Effect of Postoperative Analgesia of Oliceridine Fumarate for Gastrointestinal Function Recovery in Patients Undergoing Lumbar Spine Surgery
Osemitidine fumarate is a novel G protein-biased ligand μ-opioid receptor agonist. Previous studies have confirmed its potent analgesic effects and safety: compared with morphine, it reduces respiratory depression and…
- Trial name
- NCT07307495
- Testing
- Sufentanil, Oiceridine
- Where
- China
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Effects of Coffee Ingestion on Recovery of Bowel Function
>The Purpose of This Study Was to Determine Whether Consuming a 100-mL Cup of Coffee is Effective in Preventing or Reducing Postoperative Ileus After Laparotomy of Benign Gynecological Patients
Comparison of the effectiveness coffee (with or without caffeine) ingestion and water for reducing the duration of Postoperative ileus after Laparotomy of Benign Gynecological Patients
- Trial name
- NCT03660267
- Testing
- caffeine coffee, decaffiene coffee, still water
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Chronic Stroke
Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients
In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.
- Trial name
- NCT03392519
- Testing
- Chronic stroke
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Samsung Medical Center
Spinal Surgery, Lidocaine
Effect of Perioperative Lidocaine on Gastrointestinal Function Recovery After Lumbar Spine Surgery in Adults
Spinal surgery often involves multiple segments. The trauma of surgery is large, the duration of postoperative pain is long, and the pain is severe. Therefore, the use of opioids in perioperative period is large.
- Conditions
- Spinal Surgery, Lidocaine, Pain, Opioid Consumption
- Trial name
- NCT04922359
- Testing
- Lidocain, normal saline
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Peking University People's Hospital
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty
The primary purpose of this study is to compare early functional outcomes in patients undergoing hip resurfacing and total hip arthroplasty with the M2a-Magnum™ using more objective measures of function.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Traumatic Arthritis
- Trial name
- NCT00585988
- Testing
- Hip Resurfacing System, M2a-Magnum™ Large Metal Articulation
- Sponsor
- Biomet Orthopedics, LLC
Chronic Pain, Spasticity as Sequela of Stroke
Closed Loop Spinal Cord Stimulation for Neuromodulation of Upper Motor Neuron Lesion Spasticity
Spasticity is characterized by increased muscle tension and is a classic consequence of upper motor neuron (UMN) damage in the central nervous system, such as from stroke or trauma.
- Conditions
- Chronic Pain, Spasticity as Sequela of Stroke, Upper Motor Neuron Lesion
- Trial name
- CLONUS (NCT06384170)
- Testing
- Spinal Cord Stimulation- Closed loop
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Achilles Tendinopathy, Achilles Tendonitis
Achilles Tendinopathy, Treatment With eXercise Comparing Men and Women
This study will evaluate if there is a difference in recovery of tendon structure and mechanical properties between males and females with Achilles tendinopathy receiving exercise treatment.
- Conditions
- Achilles Tendinopathy, Achilles Tendonitis, Achilles Tendon Pain, Achilles Degeneration
- Trial name
- ATX (NCT03523325)
- Testing
- Exercise treatment
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Delaware
Stroke
fNIRS-Driven Visual Feedback Training to Restore Walking After Stroke
The objective of this clinical trial is to investigate whether intelligent visual feedback-based lower limb motor control training is more effective than conventional rehabilitation training in promoting walking ability recovery…
- Trial name
- NCT07014891
- Testing
- Intelligent Visual Feedback Motor Control Training, Bobath Ball Training
- Where
- China
- Volunteers
- 44 people
- Sponsor
- Shengjing Hospital
Stroke
Is Robot-Assisted Therapy Effective for the Upper Extremity Following a Stroke
The aim of this study was to investigate the effects on upper-limb motor function of the addition of robotic rehabilitation (RR) and conventional rehabilitation (CR) treatments to intensive trunk rehabilitation (ITR).
- Trial name
- NCT05559385
- Testing
- Robot-Assissted Therapy, Conventional Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Emresenocak
Osteoarthritis, Knee
Outcome Comparison of Two Total Knee Arthroplasty Systems: e.Motion-Pro Versus Genesis II
Recently, E.Motion-PS-Pro (B.Braun-Aesculap, Tuttlingen, Germany), a new mobile bearing knee system with a unique ball and socket post-cam mechanism was developed for use in total knee arthroplasty.
- Trial name
- NCT02276118
- Testing
- device: e.motion PS Pro, device : Genesis II
- Where
- South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Hospital
Neurodegenerative Diseases
Exploring the Recovery Function of Sleep in Neurodegeneration
The overall objective of this study is to identify the best approach for assessing the recovery function of sleep in neurodegenerative diseases associated with abnormal protein aggregation with regard to the conception of future…
- Trial name
- RFSN (NCT05402488)
- Testing
- Auditory stimulation
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Multiple Sclerosis
Exercise-Induced Irisin and Brain Changes
This single-blind, randomized controlled trial will employ a two-arm parallel design (exercise group vs. control group) with a 12-week intervention period.
- Trial name
- NCT07101653
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Firat University
Trephined Syndrome, Sinking Skin Flap Syndrome
Prevalence of Trephined Syndrome After Decompressive Craniectomy
Decompressive craniectomy is frequently used to treat increased intracranial pressure or an intracranial mass effect. Trephined Syndrome describes a neurological deterioration, which is attributed to a large craniectomy.
- Conditions
- Trephined Syndrome, Sinking Skin Flap Syndrome, Traumatic Brain Injury, Stroke
- Trial name
- TS (NCT03186157)
- Testing
- Decompressive craniectomy, Cranioplasty
- Where
- Switzerland
- Volunteers
- 41 people
- Sponsor
- University Hospital, Geneva
Knee Arthroplasty, Total, Rehabilitation Therapy
Combined Cyclic Compression Cryotherapy and Phased Rehabilitation Training for Recovery After Knee Replacement
Total knee arthroplasty (TKA) is an effective treatment for severe knee joint diseases; however, postoperative complications such as pain, swelling, and delayed functional recovery remain common challenges.
- Trial name
- NCT07089212
- Testing
- Phased Rehabilitation Training, Cyclic Compression Cryotherapy, Conventional rehabilitation treatment.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Qilu Hospital of Shandong University
Intensive Care Unit Syndrome, Intensive Care Neuropathy
Recovery From ICUAW Following Severe Respiratory and Cardiac Failure
To observe and identify determinants of recovery from intensive care unit-acquired weakness (ICUAW) following a severe cardiorespiratory failure requiring extra-corporeal membrane oxygenation (ECMO).
- Conditions
- Intensive Care Unit Syndrome, Intensive Care Neuropathy, Intensive Care (ICU) Myopathy, Acute Respiratory Distress Syndrome
- Trial name
- CLEVERER (NCT03753412)
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Spinal Cord Injuries
Tenodesis Grip Strength With Functional Hand Recovery in Cervical Spinal Cord Injury
Spinal cord injury (SCI) is devastating event, the individual become significant burden on their family and society SCI is impairments of sensory, motor and autonomic functions.
- Trial name
- NCT05356442
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Rotator Cuff Tears, Shoulder Pain
Effect of Kinesio Taping After Rotator Cuff Surgery
This prospective randomized controlled trial evaluated whether adding Kinesio Taping (KT) to a standardized postoperative rehabilitation program improves early clinical recovery after arthroscopic rotator cuff repair.
- Conditions
- Rotator Cuff Tears, Shoulder Pain, Post Operative Pain
- Trial name
- RCR-KT (NCT07375927)
- Testing
- Kinesio Taping, Standard Postoperative Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Olcay Yavuz
Hemispatial Neglect
Sleep as a Model to Understand and Manipulate Cortical Activity in Order to Promote Functional Recovery After Stroke
Brain functions are supported by multiple cell types, including neuronal and non-neuronal cells that are connected into complex networks.
- Trial name
- SSS (NCT03090711)
- Testing
- Transcranial Magnetic Stimulation (TMS), Transcranial Alternating Current Stimulation (tACS)
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery
Effect of Subanesthetic Dose of Esketamine on Sleep Quality and Recovery of Gastrointestinal Function in Patients Undergoing General Anesthesia Laparoscopic Uterine Surgery in the Early Postoperative Period
Patients undergoing gynecological surgery are at high risk of developing postoperative sleep disorders. Intraoperative opioid use is detrimental to the patient's postoperative recovery of gastrointestinal function.
- Trial name
- NCT05715671
- Testing
- esketamine
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Zhuan Zhang