Clinical trials: Recovery of Function
Osteoarthritis, Rheumatoid Arthritis
A Clinical Investigation of Recovery Following Hip Resurfacing or Total Hip Arthroplasty
The primary purpose of this study is to compare early functional outcomes in patients undergoing hip resurfacing and total hip arthroplasty with the M2a-Magnum™ using more objective measures of function.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Arthritis, Traumatic Arthritis
- Trial name
- NCT00585988
- Testing
- Hip Resurfacing System, M2a-Magnum™ Large Metal Articulation
- Sponsor
- Biomet Orthopedics, LLC
Fall Prevention, Balance, Falls
Evaluating Stumble Recovery Functions of Prosthetic Knees
The study aims to conduct a formative evaluation, along with verification, validation, and comparative analysis of the stumble recovery function in prosthetic devices by collecting relevant clinical data.
- Conditions
- Fall Prevention, Balance, Falls, Amputation of Lower Limb
- Trial name
- NCT07266454
- Testing
- Prosthetic Knee (e.g Power Knee, Navii, Rheo Knee, ...)
- Where
- 2 sites in Iceland
- Volunteers
- 50 people
- Sponsor
- Össur Iceland ehf
Stroke
Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes
This study aims to evaluate the impact of the Neurolutions Upper Extremity Rehabilitation System, known as IpsiHand, on improving functional motor control for post-stroke patients with hemiparesis.
- Trial name
- NCT04338971
- Testing
- IpsiHand Therapy
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Neurolutions, Inc.
Recovery of Function
Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET)
Basis: Evaluating Sirtuin Supplements To Benefit Elderly Trauma Patients (BES2T BET) A phase I, randomized, double-blind, placebo-controlled, single institutional pilot trial investigating the impact of nicotinamide…
- Trial name
- BestBet (NCT03635411)
- Testing
- Nicotinamide Riboside and Pterostilbene
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Elysium Health
Subacute Stroke, Upper Extremity Function
AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke
The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with…
- Trial name
- NCT07491029
- Testing
- AI-based Customized transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- NEUROPHET
Chronic Stroke, Subacute Stroke
IMPULSE - StIMulation of Brain Plasticity to Improve Upper Limb Recovery After StrokE
Stroke is a leading cause of adult long-term disability worldwide. Recovery of arm and hand function after stroke is limited to about 50% of patients and full recovery is achieved in only 12% of stroke survivors by 6 months after…
- Trial name
- IMPULSE (NCT04124367)
- Testing
- Cerebrolysin, non-invasive brain stimulation
- Where
- Austria
- Volunteers
- 4 people
- Sponsor
- Ever Neuro Pharma GmbH
Head and Neck Neoplasms, Head and Neck Lymphedema
Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-Related Lymphedema
Assessment of lymphatic structure and function pre- and post- treatment and during recovery in head and neck cancer related lymphedema patients using NIR fluorescence lymphatic imaging: Response to ICD therapy in HNC Patients.
- Conditions
- Head and Neck Neoplasms, Head and Neck Lymphedema, Head and Neck Cancer
- Trial name
- NCT02946021
- Testing
- Head and neck garments for pneumatic compression device, NIRFLI with ICG
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Tactile Medical
Kidney Diseases
Detecting Markers of Kidney Function With Intravenous Microdialysis
Patients will be invited to participate from an outpatient nephrology clinic at Hammersmith Hospital. They will have a microdialysis catheter inserted into a peripheral vein and connected to a sampling system.
- Trial name
- NCT03159806
- Testing
- Microdialysis sampling
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Accunea Ltd.
College Students of the School of Physical Education
Sports Nutrition Benefits of Weizmannia Coagulans BC99
To evaluate the clinical efficacy of Weizmannia coagulans BC99 in young Chinese patients with exercise-induced muscle damage compared with placebo, and to explore its effects on inflammatory responses and intestinal microbiota.
- Trial name
- NCT07325409
- Testing
- BC99
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Pain
Pivotal Study on the NOVABLOC System for Patients Undergoing Primary Total Knee Arthroplasty
Multi-center, randomized, blinded, sham-controlled study to determin the safety and efficacy of the NOVABLOC system on post-operative pain in patients undergoing TKA procedures.
- Trial name
- NOVABLOC-TKA (NCT07191067)
- Testing
- Percutaneous radiofrequency electrical nerve stimulation, Non-therapeutic stimulation
- Where
- 5 sites in United States
- Volunteers
- 123 people
- Sponsor
- Synaptrix, Inc.
Gastrointestinal Dysmotility
Safety and Efficacy of Ipamorelin Compared to Placebo for the Recovery of Gastrointestinal Function
Post-operative administration of ipamorelin is expected to reduce time to recovery of Gastrointestinal (GI) function in patients who have undergone partial small and/or large bowel resection.
- Trial name
- NCT01280344
- Testing
- Saline Solution for Injection, Ipamorelin
- Where
- 45 sites in United States
- Volunteers
- 320 people
- Sponsor
- Helsinn Therapeutics (U.S.), Inc
Hemiparesis
Post-stroke Motor Rehabilitation Using Functional Near-infrared Spectroscopy-based Brain-computer-interface
Chronic stroke survivors suffering from weaknesses or movement difficulties in their hand/arm are provided a system to aid in at-home rehabilitation for 6 weeks.
- Trial name
- fNIRS-PROMOTE (NCT05258591)
- Testing
- Axem Home
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Axem Neurotechnology Inc.
Coronary Artery Disease
Prasugrel/Clopidogrel Maintenance Dose Washout Study
The primary objective of the study is to describe the cumulative proportion of participants who return to baseline platelet P2Y12 receptor function over time (up to 12 days post last maintenance dose) following discontinuation of…
- Trial name
- NCT01014624
- Testing
- Prasugrel, Clopidogrel
- Where
- 4 sites in United States
- Volunteers
- 56 people
- Sponsor
- Daiichi Sankyo
Partial Nephrectomy, Kidney Cancer
Use of Human Dehydrated Amnion/Chorion (DHACM) Allograft in Partial Nephrectomy
After partial nephrectomy, kidney function decreases by about 10% overall and by about 20% in the operated kidney. This is primarily due to the loss of healthy parenchymal volume during resection of the tumor.
- Conditions
- Partial Nephrectomy, Kidney Cancer, Renal Function Aggravated
- Trial name
- NCT03323021
- Testing
- Dehydrated human amnion/chorion membrane, Standard of Care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- MiMedx Group, Inc.
Stroke, Acute, Stroke, Ischemic
Effects of Atalante Exoskeleton on Gait Recovery in Non- or Poorly Ambulatory Patients With Hemiparesis in the Acute/Subacute Phase (Month 1 to 4)
The present clinical investigation - EarlyExo, is an interventional, international, multicentric, prospective, single-blinded randomized controlled trial.
- Conditions
- Stroke, Acute, Stroke, Ischemic, Stroke, Subacute, Stroke Hemorrhagic
- Trial name
- EarlyExo (NCT06107010)
- Testing
- Use of the Atalante exoskeleton
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 66 people
- Sponsor
- Wandercraft
Traumatic Brain Injury
Hemp-Derived Botanical Dietary Supplementation During Recovery From Brain Injury
The objective of the proposed research is to evaluate adult subjects currently taking phytocannabinoid Hemp-derived botanical supplements (HDS) during recovery from traumatic brain injury.
- Trial name
- NCT03826368
- Testing
- Hemp-derived botanical dietary supplement
- Volunteers
- healthy volunteers welcome
- Sponsor
- Real Time Diagnostics Ventures INC
Degenerative Sacroiliitis, Sacroiliac Disorder
Sacroiliac Joint Fusion Intervention For Mobility, Pain Relief, and Lasting Improvement in Functional Recovery "SIMPLIFY"
The purpose of this study is to determine the clinical efficacy of The Trellis SI Joint Fusion System in unilateral sacroiliac (SI) joint fusion surgeries.
- Trial name
- SIMPLIFY (NCT07849244)
- Testing
- TRELLIS SI Joint Fusion System
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- OrthoFundamentals, LLC
Stroke, Muscle Spasticity
Anti-Gravity Treadmill and Electromagnetic Stimulation in Stroke Rehabilitation
The goal of this clinical trial is to learn if adding new technologies to standard therapy helps people recover after a stroke. It looks at adults aged 18 to 74 who recently had a stroke and need help with moving and walking.
- Conditions
- Stroke, Muscle Spasticity, Stroke Rehabilitation
- Trial name
- NCT07698639
- Testing
- Anti-Gravity Treadmill, High-Intensity Electromagnetic Stimulation, Standard Rehabilitation
- Where
- Russia
- Volunteers
- 105 people
- Sponsor
- BTL Industries Ltd.
Hip Fracture
Hip Fracture Surgery and Oral Nutritional Supplements
Senior hip fracture patients are the most vulnerable to malnutrition and protein deficiency. Low protein intake, like vitamin D deficiency, contribute to an increased risk for hip fracture.
- Trial name
- HIATUS (NCT01505985)
- Testing
- Oral nutritional Supplement
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Société des Produits Nestlé (SPN)
Digital Nerve Injury, Nerve Injury
Evaluating Therapeutic Electrical Stimulation to Improve Nerve Healing After Surgical Repair of Digital Nerve Injuries
The goal of this clinical study is to evaluate if a period of electrical stimulation delivered during the surgical repair procedure can speed up nerve healing.
- Conditions
- Digital Nerve Injury, Nerve Injury, Nerve Reconstruction, Nerve Trauma
- Trial name
- FASTR-TEN (NCT06867185)
- Testing
- Brief Electrical Stimulation Therapy, Digital Nerve Repair
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Checkpoint Surgical Inc.