Clinical trials: Reading Disorder
Developmental Language Disorder and Language Impairment, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading II
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder and Language Impairment, Specific Language Impairment, Language Development
- Trial name
- NCT07048392
- Testing
- Retrieval-based word learning: Repeated Spaced Retrieval condition, Retrieval-based word learning: Repeated Study condition
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Purdue University
Neurofibromatosis Type 1, Reading Disabilities
Neurobiology and Treatment of Reading Disability in NF-1
The goal of this trial is to determine if children with neurofibromatosis type 1 who have reading disabilities respond the same way-both behaviorally and neurobiologically-to specialized treatment programs as children with…
- Trial name
- NCT00624234
- Testing
- Tutoring Program I, Tutoring Program II
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Dyspnea
Artificial Intelligence to Improve Physicians' Interpretation of Chest X-Rays in Breathless Patients
Identifying the cause of breathlessness in acute patients in the emergency department is critical and challenging. The chest X-ray is central but challenging to read for non-radiologist physicians.
- Trial name
- XRAI (NCT05117320)
- Testing
- AI support
- Where
- Denmark
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Sleep
Citizen Science: The People's Trial: A Randomised Controlled Trial
The People's trial is an online pragmatic, randomised controlled trial to determine if reading a book in bed makes a difference to sleep in comparison to not reading a book in bed.
- Trial name
- NCT04185818
- Testing
- Reading a book
- Where
- Ireland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma
With the improvement of health system, the life span of Asians has increased tremendously especially in Malaysia. As an early preparation to be an 'aging country' in 2023, Malaysia needs to prepare infrastructure and policy to…
- Trial name
- MaGESII (NCT04736264)
- Testing
- Visual rehabilitation module: navigation and mobility, Visual rehabilitation module: exercise, Visual rehabilitation module: reading
- Where
- Malaysia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Developmental Delay
Bright by Three (BB3) Effectiveness Study
The Investigators propose to conduct a pragmatic randomized controlled trial of 350 one to four year old children and their caregivers to study the effectiveness of 1) the Bright By Three (BB3) intervention for promoting…
- Trial name
- NCT02717390
- Testing
- Bright By Three (BB3), Texts for Child Safety (TCS)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Visual Fatigue
Visual Discomfort and Reading
Reading can be an uncomfortable and difficult task for some people. Symptoms include unpleasant somatic and perceptual effects, such as eye-strain, headache, and blurred text, despite normal visual acuity.
- Trial name
- NCT00402155
- Testing
- Stress on visual discomfort
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Dyslexia
Role of Auditory Cortical Oscillations in Speech Processing and Dyslexia
This study aims at investigating the role of low-gamma activity in phonemic encoding and its implication in dyslexia. Indeed, a phonological deficit, i.e.
- Trial name
- NCT04277351
- Testing
- Transcranial alternating current stimulation
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Geneva, Switzerland
Developmental Dyslexia
Restoring Neural Oscillatory Communication in Developmental Dyslexia
Developmental dyslexia (DD) is a multifactorial disorder that hampers the education of about 10% of individuals across cultures and is associated to both phonological and visual deficits.
- Trial name
- NCT05583136
- Testing
- Parietal tACS combined with visuo-attentional training
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Ospedale San Raffaele
Autism Spectrum Disorder, Autism
Efficacy of Reading Intervention on the Brain Connectivity in Autism
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in…
- Conditions
- Autism Spectrum Disorder, Autism, Reading Problem
- Trial name
- BrainREAD (NCT05568056)
- Testing
- Visualizing and Verbalizing for Language comprehension and Thinking
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama, Tuscaloosa
Healthy Young Adults, Accommodation Disorder
Study in Young Adults to Understand How Glasses With a Small Reading Addition Affect Focusing and Eye Coordination During Vision Tasks
This clinical study aims to understand how glasses with a small reading addition affect the way the eyes focus and work together in young adults with normal near vision.
- Trial name
- BIPBIP (NCT07859917)
- Testing
- Eye exam, Questionnaires, Washout lenses
- Where
- United Kingdom
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Essilor International
Breast Cancer
Radiologic Evaluation and Breast Density (READ)
The purpose of this study is to determine whether cessation of hormone replacement therapy for one or two months before a screening mammogram will improve its performance by decreasing breast density.
- Trial name
- NCT00117663
- Testing
- temporary discontinuation of hormone therapy for 1 month, temporary discontinuation of hormone therapy for 2 months
- Where
- United States
- Volunteers
- 1,704 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Dyslexia
Study of Hierarchy of Afferents in Postural Control of Children With Dyslexia
The purpose is to determine the hierarchy of sensory afferents according to different forms of dyslexia in children. The secondary purpose is to determine sensitive and sufficiently specific posturographic indexes for standard…
- Trial name
- EQUIDYS (NCT02879786)
- Testing
- Posturographic tests, Questionnaire of motion sickness susceptibility
- Where
- France
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Age Related Macular Degeneration
Visual Function Tests in Age-related Macular Degeneration
The goal of this study is to assess a battery of visual function tests in subjects with non-exudative age-related macular degeneration
- Trial name
- NCT03275753
- Testing
- Visual Function Tests
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- ORA, Inc.
ARDS
The Educational ARDS Diagnosis Study
Without rigorous, high-quality training materials, the results of the LUNG-SAFE study examining the global incidence and outcomes of severe lung failure (acute respiratory distress syndrome [ARDS]) could be confused by either…
- Trial name
- READS (NCT02054611)
- Testing
- Online Educational Module
- Where
- 2 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Neurogenetic Diseases
Advancing Neurogenetic Diagnoses Through Long-Read Sequencing
Nucleotide repeats emerge as one of the most prolific classes of genetic variations. They have the propensity to in-crease in length across generations, and have been implicated in at least 65 known neurological/…
- Trial name
- NRGEN-NGS3 (NCT07665554)
- Testing
- Skin biopsy, blood sampling
- Where
- 2 sites in France
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Developmental Dyslexia
V5/MT Stimulation on Reading and Reading-related Measures in Developmental Dyslexia
The present study grounds on the absence of evidence-based treatment in individuals with developmental dyslexia (DD). At this topic, the present study will explore the potential effect of transcranial direct current stimulation…
- Trial name
- NCT05972200
- Testing
- Active HD-tDCS over V5/MT, Active HD-tDCS over V1
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bambino Gesù Hospital and Research Institute
Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc)
Pragmatic RCT of AI-Assisted Reading for Malignant Hepatic Lesions on CE-CT
The purpose of this multicenter pragmatic randomized controlled trial is to determine whether AI-assisted interpretation of multiphasic liver contrast-enhanced computed tomography (CE-CT) is non-inferior to standard radiology…
- Conditions
- Hepatocellular Carcinoma (HCC), Intrahepatic Cholangiocarcinoma (Icc), Hepatic Metastasis, Hepatic Hemangioma
- Trial name
- NCT07768085
- Testing
- AI-assisted abdominal CE-CT reporting, Standard abdominal CE-CT reporting without AI assistance
- Where
- China
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Shengjing Hospital
Oral Frailty, Depression
Group Reading and Oral Exercise Program for Older Adults
Depression is common among older adults and is often associated with declines in physical and oral health. Non-pharmacological, community-based interventions are needed to support both mental and physical well-being.
- Conditions
- Oral Frailty, Depression, Sarcopenia, Physical Function Decline
- Trial name
- NCT07550335
- Testing
- Reading and Oral Exercise Program
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Cystic Fibrosis
Non-invasive Prenatal Diagnosis of Monogenic Disorders by Linked-reads Technology
Description of the presence of cell-free fetal DNA in maternal plasma allowed the possibility of non-invasive prenatal diagnosis.
- Trial name
- NID (NCT03622892)
- Where
- 6 sites in France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest