Clinical trials: Rapid Sequence Induction
Rapid Sequence Induction Intubation
Effect of Cricoid Pressure on Macintosh, McGrath X-Blade and Glidescope Videolaryngoscopes in Rapid Sequence Induction Intubation
Non- Fasted patients need rapid sequence intubation. The investigators aimed to compare the intubation times of Macintosh , and McGrath X-Blade or Glidescope in these Ascenario.
- Trial name
- NCT02588157
- Testing
- Macintosh, Glidescope, McGrath MAC X-Blade
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Kocaeli University
RSI, Rapid Sequence Induction
RSI Observation Follow-up
The purpose of this prospective observational study is to determine if compliance to local guildelines for the RSI procedure, after introduction of a RSI-check list, persists over time (36-60months).
- Conditions
- RSI, Rapid Sequence Induction, Complication of Anesthesia, Compliant Behavior
- Trial name
- NCT05775029
- Where
- 2 sites in Sweden
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Jakob Zeuchner
Rapide Sequence Induction, Tracheal Intubation
Pain Assessment During Rapid Sequence Induction
Rapid sequence induction (RSI) is a standard anesthesia technique used in patients at risk of aspiration. Although tracheal intubation following RSI is a frequent and painful procedure, no study has yet evaluated nociception…
- Conditions
- Rapide Sequence Induction, Tracheal Intubation, Nociception, General Anesthesia
- Trial name
- NARSI (NCT07588165)
- Testing
- No Intervention: Observational Cohort
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace
Rapid Sequence Induction
Best Hypnotic Drug Choice for Rapid Sequence Induction in the Operating Room
The best hypnotic choice to optimize the balance between good intubation condition quality and hemodynamic stability during RSI performed in the operating theatre remained to be investigated.
- Trial name
- HYPNOTIKS (NCT06733129)
- Testing
- direct IV injection, combination of Ketamine and Propofol
- Where
- 20 sites in France
- Volunteers
- 1,218 people
- Sponsor
- Nantes University Hospital
Appendectomy
Ultrasound Assessment of Gastric Content Before Anesthesia for Appendectomy
Performing anesthetic induction for appendicectomy has two main risks : first aspiraion of gastric content causing pneumonia. Otherwise, anaphylactic risk to drugs used during anesthetic induction.
- Trial name
- EGASTA (NCT02983175)
- Testing
- ultrasound assessment of gastric content
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Endotracheal Intubation in Bed up Head Elevation Position in Rapid Sequence Induction
Comparison of Bed up Head Elevated Position With Sniffing Position in Rapid Sequence Induction.
This study is aimed to conduct a randomised controlled trial comparing endotracheal intubation (ETI) in bed up head elevation BUHE position versus sniffing position in simulated rapid sequence induction (RSI).
- Trial name
- NCT03912935
- Testing
- comparison between two different intubating position
- Where
- Malaysia
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Rapid Sequence Induction
EUROpE-RSI (EURopean Online Evaluation RSI Study)
The investigators want to identify and show differences in standards and procedures of in-hospital rapid sequence induction by collecting data with an online survey for anaesthetist in Europe.
- Trial name
- EUROpE-RSI (NCT02751684)
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Universitätsklinikum Köln
Rapid Sequence Induction and Intubation, Rocuronium
Comparison of Standard rapi̇d Sequential Intubation Protocol With Rocuronium in Emergency Department
Airway management and advanced airway management are the issues that are applied every day in emergency services and that the emergency physician should know best.
- Trial name
- NCT05343702
- Testing
- priming with rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cricoid Pressure
Effect of Incorrectly Applied Cricoid Pressure During Rapid Sequence Induction. Evaluation With High-resolution Manometry.
During emergency anesthesia (rapid sequence induction) , a firm pressure is applied to the cricoid cartilage of the patient in order to prevent passive regurgitation of gastric content into the pharynx.
- Trial name
- NCT02161601
- Testing
- Cricoid Pressure
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Örebro University, Sweden
Rapid Sequence Induction, Rapid Sequence Intubation
Rapid Sequence Intubation With Rocuronium in Elderly Patients
With the prolongation of life expectancy, the frequency of surgical intervention and anesthesia increases in elderly patients. The rapid Sequence Intubation(RSI) technique is preferred in patients with aspiration risk and who…
- Conditions
- Rapid Sequence Induction, Rapid Sequence Intubation, Rocuronium
- Trial name
- NCT05067829
- Testing
- Train of four(TOF)
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Ankara City Hospital Bilkent
Intubation Conditions
Intubating Conditions During Rapid Sequence Induction in Elderly With Either Suxamethonium 1.0 mg/kg or Rocuronium 1.0 mg/kg
The aim of this study is to determine the proportion of excellent tracheal intubation conditions at 60 seconds after administration of either rocuronium 1.0 mg/kg or suxamethonium 1 mg/kg in patients with age ≥ 80 years during…
- Trial name
- NCT04868409
- Testing
- Suxamethonium, Rocuronium
- Where
- 4 sites in Denmark
- Volunteers
- 102 people
- Sponsor
- Matias Vested
Intubation, Intratracheal, Laryngoscopes
The Clarus Video System and Direct Laryngoscope for Rapid Sequence Induction Intubation With Cricoid Pressure
During an emergency endotracheal intubation, rapid sequence induction intubation with cricoid pressure is frequently implemented to prevent aspiration pneumonia.
- Conditions
- Intubation, Intratracheal, Laryngoscopes, Anesthesia, General
- Trial name
- NCT03841890
- Testing
- the Clarus Video System as a video stylet, the Clarus Video System as a lightwand, direct laryngoscope
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Delayed Sequence Intubation, Rapid Sequence Induction and Intubation
Comparison of Peri-intubation Oxygenation Values and Complications in Patients Intubated With the Delayed Versus Rapid Sequence Intubation Protocols
This study compares two different methods of helping patients breathe by placing a tube in their airway (intubation) in an emergency setting.
- Conditions
- Delayed Sequence Intubation, Rapid Sequence Induction and Intubation, Intubation, Intubation Complications
- Trial name
- DSI vs RSI (NCT07380763)
- Testing
- Delayed Sequence Intubation, Rapid Sequence Intubation
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Anesthesia Intubation Complication
Modified Rapid Sequence Induction in Morbidly Obese Patients
This study investigates the effect of 4 different methods of rapid sequence induction (RSI) in morbidly obese patients on the amount of air insufflation into the stomach.
- Trial name
- NCT03239236
- Testing
- Rapid sequence induction t-RSI, Rapid sequence induction m-RSI-PEEP, Rapid sequence induction m-RSI-vent
- Where
- Austria
- Sponsor
- Medical University of Vienna
Anesthesia, Hypoxia
Pre-oxygenation With High-flow Nasal Cannula in Adults During Rapid Sequence Induction Anesthesia
It has been demonstrated that Transnasal Humidified Rapid Insufflation Ventilatory Exchange used during preoxygenation for emergency surgery is at least equally effective as preoxygenation compared to standard tight fitting mask.
- Conditions
- Anesthesia, Hypoxia, Surgery, Acute
- Trial name
- PRIOR2 (NCT03516175)
- Testing
- High flow transnasal oxygen, Pre oxygenation using tight fitting facemask
- Where
- 6 sites in Sweden, Switzerland
- Volunteers
- 350 people
- Sponsor
- Karolinska University Hospital
Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement
Intubating Condition After Magnesium Pre-treatment
Magnesium had an inhibitory effect on neuromuscular transmission and caused a decrease in muscle fiber membrane excitability. It reduces the amount of acetylcholine that is released at the motor nerve terminal by decreasing the…
- Conditions
- Easy of Laryngoscopy Manipulation, Vocal Cord Position or Movement, Patient Reaction to Intubation and Cuff Inflation, Mean Arterial Pressure
- Trial name
- NCT01153256
- Testing
- magnesium sulphate, normal saline
- Where
- South Korea
- Volunteers
- 168 people
- Sponsor
- Seoul National University Bundang Hospital
Intubation in Intensive Care Units
Delayed Against Rapid Sequence Induction in Adults With Medical Diseases Undergoing Emergency Endotracheal Intubation.
The goal of this clinical trial is to learn if it is feaseble to conduct a superiority trial comparing two methods for endotracheal intubation in critically ill patients.
- Trial name
- DARSITUBE (NCT06940219)
- Testing
- Delayed Sequence Induction, Modified Rapid Sequence Induction
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Leipzig University Medical Center
Pulmonary Aspiration of Gastric Contents, Emergency Surgery
Gastric Ultrasound for Airway Management in Emergency Patients
This prospective observational cohort study evaluates the association between gastric residual content and volume, assessed by point-of-care gastric ultrasound (PoCUS), and the choice of airway management technique (Rapid…
- Conditions
- Pulmonary Aspiration of Gastric Contents, Emergency Surgery, Gastric Residual Volume, Airway Management
- Trial name
- NCT07640165
- Testing
- Preoperative Gastric Point-of-Care Ultrasound (PoCUS)
- Where
- Indonesia
- Volunteers
- 43 people
- Sponsor
- Universitas Indonesia
Hemodynamic Instability During Anesthesia, Induction Anesthesia
Low-dose Propofol Plus High-dose Alfentanil in Rapid Sequence Induction
This study compares four different anesthesia induction regimens to see which one provides the most stable blood pressure and heart rate during rapid sequence intubation.
- Conditions
- Hemodynamic Instability During Anesthesia, Induction Anesthesia, Intubation
- Trial name
- NCT07730918
- Testing
- propofol, alfentanil, Sufentanil
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Aoyang Hospital Affiliated to Jiangsu University
Intra-tracheal Intubation
Assessment of Remifentanil for Rapid Sequence Induction and Intubation in Full Stomach Patient Compared to Muscle Relaxant
REMICrush is a French multicentric non inferiority simple blind randomized clinical trial that will compare the use of Remifentanil to muscle relaxant (reference treatment) for anesthetic rapid sequence intubation in terms of…
- Trial name
- REMICRUSH (NCT03960801)
- Testing
- Remifentanil group, neuromuscular blockade group
- Where
- 13 sites in France
- Volunteers
- 1,150 people
- Sponsor
- Nantes University Hospital