Clinical trials: Randomized Controlled Trial (RCT)
Small Bowel Disease
Novel Motorized Spiral Enteroscopy Vs Single Balloon Enteroscopy In Patients With Small Bowel Disorders- A RCT
STUDY OBJECTIVES: 1. Primary objective: Rate of total enteroscopy (TER) by means of NMSE or SBE with: Complete antegrade approach or combined antegrade and retrograde approach 2. Secondary objective: 1.
- Trial name
- MOTOR-AIG-01 (NCT05548140)
- Testing
- Novel Motorized Spiral Enteroscopy
- Where
- 2 sites in India
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Intracranial Aneurysm, CT Angiography
IDEAL Study: Blinded RCT for the Impact of AI Model for Cerebral Aneurysms Detection on Patients' Diagnosis and Outcomes
This study (IEDAL study) intends to prospectively enroll more than 6450 patients who will undergo head CT angiography (CTA) scanning in the outpatient clinic.
- Conditions
- Intracranial Aneurysm, CT Angiography, Deep Learning, Double Bind Interaction
- Trial name
- IDEAL (NCT06118840)
- Testing
- True-AI-integrated intracranial aneurysms diagnosis strategy
- Where
- 21 sites in China
- Volunteers
- 6,450 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Communication
Supporting Doctor-patient Communication in Oncology
Aims of study While various communication aids have been evaluated separately, no studies have taken a coordinated approach combining aids with different goals to evaluate their combined impact.
- Trial name
- NCT02278900
- Testing
- Communication aids
- Where
- Norway
- Volunteers
- 180 people
- Sponsor
- University Hospital of North Norway
Lateral Epicondylitis
Tennis Elbow Trial
Epi-X is a multicentered randomized controlled clinical trial of chronic lateral epicondylitis with parallel group design and two phases.
- Trial name
- Epi-X (NCT00888225)
- Testing
- Eccentric exercise, Concentric exercise
- Where
- 2 sites in Sweden
- Volunteers
- 205 people
- Sponsor
- Uppsala University
Social Anxiety Disorder
Emotion Regulation During RCT of CBT vs. MBSR for Social Anxiety Disorder
The purpose of the study is to investigate the immediate and longer-term impact of Cognitive-Behavioral Group Therapy (CBGT) versus Mindfulness-Based Stress Reduction (MBSR) for patients with Social Anxiety Disorder.
- Trial name
- NCT02036658
- Testing
- Cognitive Behavioral Group Therapy, Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Stanford University
Type 2 Diabetic Patients
A Study Comparing Degu Insulin Liraglutide Injection With Premixed Insulin on the Prognosis of Diabetes Mellitus
A randomized open, positive parallel controlled clinical study design was adopted. Participants were randomly assigned 1:1 according to inclusion criteria and exclusion criteria into two treatment regiments: Delu insulin…
- Trial name
- TLI vs PMI (NCT06925334)
- Testing
- Degludec insulin
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Ventricular Assist Device, Psychosocial Factors
Improved Self-management for Patients on Ventricular Assist Device (VAD) Support - Phase 3
The number of patients suffering from end-stage heart disease challenges healthcare services in the western world, where an estimated 1-2% of the population suffer from this chronic condition.
- Conditions
- Ventricular Assist Device, Psychosocial Factors, Self-management
- Trial name
- SELMA (NCT04526964)
- Testing
- Self-management curriculum
- Where
- 4 sites in Germany
- Volunteers
- 140 people
- Sponsor
- University of Freiburg
Coronary Heart Disease
A Programme Using a Mobile Application Versus Phone Advice on Patients at Risk of Coronary Heart Disease - A RCT
It aims to compare the effects of a professional -led support programme using a mobile application versus telephone advice on clients at risk of coronary heart disease.
- Trial name
- NCT04968067
- Testing
- App group, Nursing telephone advice (NTA) group
- Where
- Hong Kong
- Volunteers
- 168 people
- Sponsor
- The Hong Kong Polytechnic University
COPE, Breast Cancer
Creating Opportunities For Personal Empowerment (COPE) In Women With Breast Cancer During First-Line Therapy: A Pilot Randomized Controlled Trial
To learn if the Creating Opportunities for Personal Empowerment (COPE) intervention is feasible, acceptable, and helpful (compared to usual care) in women with breast cancer who are receiving first line treatment.
- Conditions
- COPE, Breast Cancer, First Line Therapy, Randomized Controlled Trial (RCT)
- Trial name
- NCT07610499
- Testing
- Standard of Care (SOC), Intervention sessions
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- M.D. Anderson Cancer Center
Colorectal Carcinoma
CoGENES Randomized Controlled Trial (RCT)
This clinical trial evaluates the effectiveness of trained community engagement specialists for improving communication on colorectal cancer (CRC) prevention and genetic testing among Hispanic/Latino/a/x (H/L) communities.
- Trial name
- NCT07229443
- Testing
- Best Practice, Health Promotion and Education, Survey Administration
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Post Partum Hemorrhage
S-Condom Uterine Tamponade in Controlling Atraumatic Postpartum Haemorrhage (PPH) - RCT
A Randomized Controlled Non inferiority Trial will be conducted to see the feasibility, acceptability and efficacy of S-Condom Uterine Tamponade in women with atraumatic PPH and not responding to first line of treatment.
- Trial name
- NCT05559840
- Testing
- S-Condom Uterine Tamponade, Traditional condom catheter
- Volunteers
- 82 people
- Sponsor
- Mamms Institute of Fistula and Womens Health
Osteoporosis
Patient Education in Osteoporosis (RCT-PATOS)
The objective of this randomized clinical trial is to assess both the effectiveness and underlying mechanisms of patient education for individuals aged 50 years and older with osteoporosis.
- Trial name
- RCT-PATOS (NCT07367776)
- Testing
- Digital patient education, Face-to-face patient education, General information on osteoporosis (open website)
- Where
- 7 sites in Sweden
- Volunteers
- 600 people
- Sponsor
- University Hospital, Linkoeping
Mild Cognitive Impairment
Transcranial Magnetic Stimulation in Patients With Mild Cognitive Impairment - RCT Trial
The study is planned as a randomized, double-blind, and sham-controlled parallel trial, in which raters and participants will be blinded to the group selection.
- Trial name
- NCT05730296
- Testing
- TMS
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw Medical University
Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3)
Efficacy of Bioactive Collagen Peptide Compared to Glucosamine and Chondroitin Sulphate in Grade I-III Knee Osteoarthritis
Brief Summary The goal of this clinical trial is to learn whether bioactive collagen peptide works as well as glucosamine and chondroitin sulphate for improving pain, stiffness, physical function, and quality of life in adults…
- Trial name
- NCT07746466
- Testing
- Bioactive Collagen Peptide, Glucosamine and Chondroitin Sulphate
- Where
- Pakistan
- Volunteers
- 150 people
- Sponsor
- Liaquat National Hospital & Medical College
Plantar Fascitis
Shockwave Therapy for Plantar Fasciitis RCT
Inflammation of the plantar fascia is known as plantar fasciitis and is commonly seen in active or overweight individuals. It can be treated via conservative or surgical therapies.
- Trial name
- NCT04332471
- Testing
- Radial shockwave therapy, Focused shockwave therapy, Shockwave therapy device
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Hospital for Special Surgery, New York
Dental Anxiety
Evaluation of Pain Perception and Heart Rate in Children Who Received Dental Anesthesia
The aim of this single-blind split-mouth study is to compare traditional syringe technique versus computer-controlled Wand® anesthetic System to evaluate pain perception, assessed with Visual Numerical Rating Scale, and heart…
- Trial name
- RCT (NCT03348800)
- Testing
- Dental anesthesia
- Where
- Italy
- Volunteers
- 76 people
- Sponsor
- Catholic University of the Sacred Heart
Health Behavior
An RCT Promoting HPV Vaccination Among Chinese MSM
Objectives: To evaluate efficacies of two online and theory-based interventions [HC: health communication only and HC-MI health communication plus motivational interviewing (MI)] in increasing uptake of three doses of HPV…
- Trial name
- NCT03286907
- Testing
- Online videos, Online videos and MI, Control group
- Where
- Hong Kong
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Post-traumatic Stress Disorder
Effectiveness of a Brief Intensive Trauma Treatment for Adolescents With (s)PTSD: a Multi-center RCT
The primary objective of this study is to examine the effectiveness of a Brief Intensive Trauma Treatment (BITT) for adolescents with (s)PTSD.
- Trial name
- NCT06143982
- Testing
- Brief Intensive Trauma Treatment
- Where
- 3 sites in Bonaire, Saint Eustatius and Saba , Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Single-port Video-assisted Thoracoscopic Surgery
RCT of Uniport VATS for Lung Cancer
Video-assisted thoracoscopic surgery (VATS) has been widely used for non-small cell lung cancer (NSCLC) for nearly two decades. Usually, it was applied through three ports with at least one drainage after surgery, which often…
- Trial name
- NCT04212481
- Testing
- uniport video-assisted thoracoscopic surgery, two ports video-assisted thoracoscopic surgery, three ports video-assisted thoracoscopic surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Second Hospital of Shandong University
Peripheral Vascular Diseases
Effects of Remote Ischemic Preconditioning on Restenosis Post Lower Limb Revascularization Angioplasty
The investigators will established relation between restenosis and inflammatory response to shearing stress caused by angioplasty suggest that any mechanism that affect inflammatory response can consequently affect the restenosis…
- Trial name
- NCT02406131
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Ireland
- Volunteers
- 40 people
- Sponsor
- National University of Ireland, Galway, Ireland