Clinical trials: Radiotherapy; Image-Guided
Bone Metastases
Biological Image Guided Antalgic Stereotactic Body Radiotherapy of Bone Metastases
In various common cancers, the skeleton is a preferred site of metastasis. These bone metastases are the most common cause of cancer-related pain, which significantly impair quality of life.
- Trial name
- NCT01429493
- Testing
- Conventional Radiotherapy, Biological image-guided radiotherapy with conventional dose., Biological image-guided SBRT with dose-escalation.
- Where
- 2 sites in Belgium
- Volunteers
- 54 people
- Sponsor
- University Hospital, Ghent
Prostate Cancer
Multi-target Tracking in Prostate Radiotherapy Using MLC and KIM
Assessing the feasibility of implementing real-time multi-leaf collimator (MLC) tracking to account for the relative motion of the moving prostate tumour target and the static pelvic nodal target for high-risk prostate cancer…
- Trial name
- KOALA (NCT02588846)
- Testing
- Combined real-time use of 'Multi-Leaf Collimator Adaptation' and 'kV Intrafraction Monitoring'
- Where
- Australia
- Sponsor
- Royal North Shore Hospital
Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer
Image-Guided Hypofractionated Radiation Therapy With Stereotactic Body Radiation Therapy Boost and Combination Chemotherapy in Treating Patients With Stage II-III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery
This clinical trial studies image-guided hypofractionated radiation therapy (RT) when given together with hypofractionated RT boost and combination chemotherapy in treating patients with stage II-III non-small cell lung cancer…
- Conditions
- Adenocarcinoma of the Lung, Adenosquamous Cell Lung Cancer, Large Cell Lung Cancer, Recurrent Non-small Cell Lung Cancer
- Trial name
- NCT01345851
- Testing
- hypofractionated radiation therapy, laboratory biomarker analysis, image-guided radiation therapy
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Prostate Cancer
Radiation Therapy in Combination With Brachytherapy for Clinically Localized, Intermediate Risk Prostate Cancer
The purpose of this study is to test the safety and side effects "of "ultra-hypofractionated" radiation therapy when used after brachytherapy (radiation implants).
- Trial name
- NCT02280356
- Testing
- external beam radiation therapy, brachytherapy, questionnaires
- Where
- 6 sites in United States
- Volunteers
- 45 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
Partial Breast Irradiation Using Non Invasive Approach for Early Stage Breast Cancer
The purpose of this study is to evaluate the rate of early and intermediate toxicity related to the AccuBoost System for delivery of APBI in women with resected, early stage breast cancer.
- Trial name
- NCT01463007
- Testing
- Accelerated partial breast irradiation, Extended Follow up
- Where
- 4 sites in United States
- Volunteers
- 40 people
- Sponsor
- Jaroslaw Hepel
Head and Neck Neoplasm
Masks Against Surface-Scanning for Radiation Therapy Immobilisation in Head and Neck Cancer (MASSC)
The purpose of this study is to investigate the feasibility of using open masks or no masks in combination with optical surface scanning for radiotherapy in patients with head and neck cancer.
- Trial name
- MASSC (NCT05011500)
- Testing
- Radiotherapy with Closed Mask, Radiotherapy with Open Mask and Surface Scanning, Radiotherapy with No Mask
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Cancer Research Antwerp
Cancer
Prospective Evaluation of Radiotherapy Using Magnetic Resonance Image Guided Treatment
The purpose of PERMIT is to collect information on the treatment of radiotherapy patients using a new radiotherapy machine that includes magnetic Resonance (MR) imaging (MR linac) to guide treatment.
- Trial name
- PERMIT (NCT03727698)
- Testing
- MR Linac
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Institute of Cancer Research, United Kingdom
Lymphedema, Musculoskeletal Complications
Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or Leg
RATIONALE: Image-guided radiation therapy uses high-energy x-rays to kill tumor cells. Specialized radiation therapy that delivers a lower dose of radiation directly to the tumor may kill more tumor cells and cause less damage to…
- Conditions
- Lymphedema, Musculoskeletal Complications, Radiation Fibrosis, Radiation Toxicity
- Trial name
- NCT00589121
- Testing
- Chemotherapy, Radiation therapy, Surgery
- Where
- 17 sites in United States, Canada
- Volunteers
- 98 people
- Sponsor
- Radiation Therapy Oncology Group
The Aim of Our Study is to Prospectively Evaluate the Optic Neuropathy in Nasopharynx Cancer Patients
OPHTHALMOLOGIC EVALUATION OF RADIATION-RELATED OPTIC NEUROPATHY FOLLOWING IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY (IMRT) FOR NASOPHARYNGEAL CARCİNOMA
Primary treatment in nasopharynx cancers is radiotherapy (RT) or chemoradiotherapy (CRT) depending on the stage of the tumor. According to the guidelines, the dose of radiotherapy for primary tumors varies between 66-70 Gy.
- Trial name
- ORONIN (NCT04724590)
- Testing
- IMRT(IMAGE GUIDED INTENSITY-MODULATED RADIATION THERAPY )
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Prostate Cancer
Feasibility Trial Of Image Guided External Beam Radiotherapy With Or Without High Dose Rate Brachytherapy Boost In Men With Intermediate-Risk Prostate Cancer
This research is being done because investigators involved in this study would like to compare image guided external beam radiation therapy (IGRT) to IGRT plus HDR brachytherapy boost to see which treatment is better and what the…
- Trial name
- NCT01982786
- Testing
- Image guided external beam radiotherapy with or without brachytherapy boost, Brachytherapy
- Where
- 9 sites in Canada
- Volunteers
- 57 people
- Sponsor
- Canadian Cancer Trials Group