Clinical trials: Radicular Pain
Lumbosacral Radicular Syndrome
PRF Treatment for Patients With Chronic Lumbosacral Radicular Pain Compared to Conventional Medical Management
The purpose of the study is to evaluate the effect of PRF treatment adjacent to the lumbar dorsal root ganglion (DRG) of L5 or S1 in patients with a chronic lumbosacral radicular syndrome (LRS).
- Trial name
- NCT00991237
- Testing
- Pulsed Radiofrequency
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Pain, Postoperative
Single and Double Injection Bilateral Thoracic Paravertebral Blocks in Reduction Mammaplasty
This study compares the analgesic effects and dermatomal blockade distributions of single and double injection bilateral thoracic paravertebral block (TPVB) techniques in patients undergoing reduction mammaplasty.
- Trial name
- NCT04517331
- Testing
- Thoracic paravertebral block-single injection, Thoracic paravertebral block-double injection
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain, Chronic
Effectiveness of Ultrasound Versus Fluoroscopy Guided S1 Injections and Radiofrequency
The investigators aim to compare the effect of ultrasound versus floroscopy guided pulsed radiofrequency treatment of the lumbar dorsal root ganglion (DRG) of S1 in patients with a chronic lumbosacral radicular pain.
- Trial name
- NCT05247892
- Testing
- Ultrasound-guided S1 Radiofrequency stimulation, Fluoroscopic-guided S1 Radiofrequency stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Chronic Radicular Back Pain, Lumboischialgia
High-tone External Muscle Stimulation for Pain Reduction
Sciatica is a common pain problem that affects not only the patient but also constitutes a socioeconomic burden and thus affects the whole society. So far, current pharmacologic therapies are inadequate for many patients.
- Conditions
- Chronic Radicular Back Pain, Lumboischialgia, Cervico Brachialgia
- Trial name
- HTEMS (NCT02151565)
- Testing
- HTEMS, TENS
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- West German Center of Diabetes and Health
Low Back Pain
Adjunctive 5% Lidocaine Patches for Acute Non-radicular Low Back Pain in Emergency Department Patients
This study will evaluate the addition of lidocaine % transdermal patches to standard therapy in the treatment of acute non-radicular low back pain in patients discharged from the Emergency Department.
- Trial name
- NCT03301766
- Testing
- lidocaine 5% patch, standard therapy, Non-medicated patch
- Where
- United States
- Sponsor
- Cook County Health
Cervical Radiculopathy, Cervical Radicular Pain
Non-organic Signs to Predict Outcomes for Neck Pain
Neck pain is the 4th leading cause of disability in the world, with approximately 50% being neuropathic in nature. Epidural steroid injections (ESI) are one of the most commonly used treatments for cervical radiculopathy.
- Trial name
- NCT04320836
- Testing
- Cervical epidural steroid injection
- Where
- 3 sites in United States, South Korea
- Volunteers
- 78 people
- Sponsor
- Johns Hopkins University
Radicular Pain, Lumbar Surgery
Return to Work After Lumbar Surgery: a Nationwide Survey of Spinal Surgeons' Practices
This national cross-sectional survey investigates the current practices and perceptions of Belgian spinal surgeons regarding return to work (RTW) after lumbar surgery for radicular pain.
- Conditions
- Radicular Pain, Lumbar Surgery, Radicular Pain Related to Lumbosacral Disc Disease, Fusion of Spine, Lumbar Region
- Trial name
- NCT07193758
- Where
- Belgium
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region
Radiofrequency for Chronic Radicular Lumbar Pain: Geriatric vs. Young Patients
This study aims to evaluate the treatment response and lumbar magnetic resonance imaging (MRI) findings of patients who have undergone pulsed radiofrequency therapy for chronic radicular lumbar pain at the dorsal root ganglia.
- Conditions
- Radiculopathy Lumbar, Radiculopathy, Lumbosacral Region, Chronic Pain
- Trial name
- NCT06903949
- Testing
- Lumbar Dorsal Root Ganglia Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ankara Etlik City Hospital
Lumbar Radiculopathy
Pulsed Radiofrequency in Chronic Lumbosacral Radicular Pain
To evaluate the efficacy of usage of High-voltage pulsed radiofrequency on DRG in comparison to standard-voltage pulsed radiofrequency intervention in patients with chronic lumbosacral radicular pain
- Trial name
- NCT05713032
- Testing
- Pulsed radiofrequency on lumbar dorsal root ganglion
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Alexandria University
Pain, Postoperative, Pain, Chest
Pharmacokinetic Profile and Dermatomal Coverage of the Erector Spinae Plane Block
The goals of this study are as follows: 1. to confirm the safe dosing of ropivacaine for the erector spinae plane block 2. develop a pharmacokinetic profile of the erector spinae plane block, which will help demonstrate how…
- Trial name
- NCT03874806
- Testing
- Ropivacaine 0.25%-NaCl 0.9% Injectable Solution, Ropivacaine 0.2%-NaCl 0.9% Injectable Solution
- Where
- United States
- Sponsor
- Virginia Commonwealth University
Cervical Radiculopathy
Cervical Interlaminar Versus Transforaminal Epidural Steroid Injection
compare cervical interlaminar epidural injection of betamethasone (9mg) and cervical transforaminal epidural injection of dexamethasone (15 mg) for cervical radicular pain
- Trial name
- NCT03165825
- Testing
- Transforaminal Epidural Steroid Injection with Dexamethasone, Interlaminar Epidural Steroid Injection with Betamethasone
- Sponsor
- Vanderbilt University Medical Center
Lumbar Disc Herniation With Radiculopathy
Comparison of the Effectiveness of Ultrasound-Guided Periradicular Injections in Patients With Lumbar Radicular Pain
This study aims to compare the effects of different ultrasound-guided periradicular injection solutions in patients with chronic unilateral radicular pain caused by a single-level lumbar disc herniation.
- Trial name
- NCT07771374
- Testing
- Lidocaine Hydrochloride 2% Injection Solution, Dexamethasone 4 Mg/mL Injectable Solution, Dextrose 5% Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
Chronic Low Back Pain, Radiculopathy
Effect of Alexithymia on Treatment Response to Transforaminal Epidural Steroid Injections in Chronic Low Back Pain
Low back pain and lumbosakral radiculopathy represent common clinical challenges substantially diminishing health-related quality of life and work productivity.
- Conditions
- Chronic Low Back Pain, Radiculopathy, Alexithymia
- Trial name
- NCT07828132
- Testing
- Psychometric Assessment and Clinical Follow-up Battery
- Volunteers
- 60 people
- Sponsor
- Marmara University
Lumbar Radiculopathy, Radicular Low Back Pain
R³ Rehab Pathway Versus Usual Care After Lumbar Radicular Surgery
The R³ trial is a multicentre cluster randomized controlled trial evaluating an evidence-based, person-centred rehabilitation pathway for patients undergoing lumbar surgery for radicular pain.
- Trial name
- R³ (NCT07313566)
- Testing
- R³ Rehabilitation Pathway
- Where
- 16 sites in Belgium
- Volunteers
- 480 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Low Back Pain
Traction in Vertical Sitting Position Versus Supine Lying Position in Patients of Chronic Radicular Low Back Pain
The primary objective of the study is to determine the effects of vertical sitting versus supine lying traction on pain, range of motion, and function in patients with chronic radicular low back pain (CRLBP).
- Trial name
- NCT05794347
- Testing
- Traction
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Lumbar Radicular Pain
Interest of Virtual Reality Headset During Injection in Patients With Back Pain and Sciatica
For a few years, publications have been published concerning the use of virtual reality headsets in the field of medicine and particularly in various specialities.
- Trial name
- Epi-RéV (NCT05505968)
- Testing
- Virtual Reality Headset
- Where
- France
- Volunteers
- 116 people
- Sponsor
- CHU de Reims
Acute and Chronic Non-radicular LBP
Topical Lidocaine Patch in Low Back Pain
Patients with acute or chronic Lower Back Pain (LBP) participated in a Phase IV clinical trial to assess the effectiveness of Lidoderm administered once daily (q24h) for 2 weeks in the treatment of acute and chronic LBP.
- Trial name
- NCT00904540
- Testing
- Lidoderm®
- Where
- 7 sites in United States
- Volunteers
- 131 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Chronic Pain
Transforaminal Epidural Platelet Rich Plasma Versus Epidural Steroid Injection for Lumbosacral Radicular Pain
Lumbosacral radicular pain is present in around 40% of cases of low back pain. It is usually caused by irritation and inflammation of the nerve root, and patients typically experience pain radiating from the back to the lower…
- Trial name
- NCT05129085
- Testing
- Dexamethasone 4mg, epidural platelet rich plasma injection
- Where
- 2 sites in Hong Kong
- Volunteers
- 70 people
- Sponsor
- The University of Hong Kong
Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis
Prospective Observation of the Fluoroscopy-guided Cervical Epidural Approach Using the Contralateral Oblique View
The aim of the present study is to investigate the safety and clinical utility of contralateral oblique view for fluoroscopic guided cervical epidural access.
- Conditions
- Cervical Intervertebral Disc Disease, Cervical Spinal Stenosis, Cervical Radicular Pain, Herpes Zoster
- Trial name
- NCT04774458
- Testing
- Fluoroscopic-guided cervical epidural access
- Where
- South Korea
- Volunteers
- 439 people
- Sponsor
- Asan Medical Center
Radiculopathy Lumbar
Glucocorticoid Injection in Patients With Lumbar Radicular Pain
The purpose of this study is to demonstrate the efficacy of intramuscular betamethasone injection on pain and other clinical parameters in patients with radicular pain due to lumbar disc herniation.
- Trial name
- NCT05571046
- Testing
- Glucocorticoids
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University