Clinical trials: Racial Disparities
Smoking Cessation
Addressing Racial/Ethnic Tobacco Health Disparities Via Group Intervention
The purpose of this study is to test the effects of a group smoking cessation program. The study will also examine individual differences in response to the intervention program.
- Trial name
- NCT02511236
- Testing
- Group Cognitive Behavioral Therapy, General Health Education, Transdermal Nicotine Patch
- Where
- 2 sites in United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Sudden Cardiac Death, Heart Failure
Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy
VIVID is a prospective, multicenter, randomized clinical trial in African American patients that will to evaluate: (1) the effect of an educational video on knowledge of sudden cardiac death (SCD) and implantable cardioverter…
- Trial name
- VIVID (NCT02819973)
- Testing
- Educational Video1, Educational Video 2, Usual Care 3
- Where
- 14 sites in United States
- Volunteers
- 343 people
- Sponsor
- Duke University
Type 2 Diabetes, Pre-Diabetes
Power-Up: An Effectiveness Trial of the Diabetes Prevention Program
The goal of this study is to address the risk of diabetes among men by creating a Diabetes Prevention Program (DPP) tailored to men.
- Trial name
- Power-Up (NCT04104243)
- Testing
- Men-Tailored DPP (Power-Up)
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- Albert Einstein College of Medicine
Behavior
Evaluation of Link for Equity (School Staff Population)
The investigators propose to develop and evaluate Link for Equity, a trauma-informed system of care. Link, a system of support for ACE-affected children, is composed of universal school Trauma-Informed Care.
- Trial name
- NCT04026477
- Testing
- Immediate Universal Trauma-Informed Care and Cultural Humility Training, Waitlisted Universal Trauma-Informed Care and Cultural Humility Training
- Where
- United States
- Volunteers
- 1,612 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hypertension
Impact of Computerized Decision Support on Racial/Ethnic Disparities in Hypertension Outcomes
In response to the Finding Answers: Disparities Research for Change call for proposals by the Robert Wood Johnson Foundation, we were funded to evaluate the effectiveness of a planned computerized decision support (CDS)…
- Trial name
- NCT01083940
- Testing
- Computerized reminders on hypertension intensification
- Where
- United States
- Volunteers
- 3,600 people
- Sponsor
- Brigham and Women's Hospital
Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
A Culturally Sensitive Values-Guided Aid for End of Life Decision-Making
The goal of this research agenda is to improve the quality of end-of-life care by explicitly identifying values that will guide the decision-making process, with a particular emphasis on the role of ethnic, racial and cultural…
- Conditions
- Congestive Heart Failure, Chronic Obstructive Pulmonary Disease, Cirrhosis, Colon Carcinoma
- Trial name
- Aim3 (NCT00122135)
- Testing
- Values Inventory (VI)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
HCC, Racial Disparities
Effect of the HCC Liver-Link Intervention
This study is a pilot, multi-center randomized controlled trial testing the HCC Liver-Link intervention, a culturally tailored, multi-level program designed to reduce racial disparities in hepatocellular carcinoma (HCC) care.
- Trial name
- NCT06728293
- Testing
- Liver Link
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Prostatic Neoplasm
Dietary Factors and Racial Disparities in Prostate Cancer Aggressiveness
The North Carolina-Louisiana Prostate Cancer Project is a population-based case-only study of over 2,000 men newly diagnosed with prostate cancer designed to address racial differences in prostate cancer aggressiveness and…
- Trial name
- PCaP (NCT03289130)
- Volunteers
- 2,258 people
- Sponsor
- University of South Carolina
Depressive Symptoms
Resilience Against Depression Disparities (Also Known as Resilience Education to Reduce Depression Disparities)
Depressive symptoms and disorders are among the most common adult health conditions with a lifetime prevalence of 15-20% and are a leading cause of disability /morbidity worldwide.
- Trial name
- RADD (NCT02986126)
- Testing
- Resiliency Class, Resource for Services (RS)
- Where
- 22 sites in United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- Bowen Chung, MD, MSHS
Opioid Use Disorder
Using AI and Peer Coaching to Address Racial Disparities Among People Who Use Opioids
Black and Latinx people who use opioids are disproportionately impacted by opioid overdose deaths. The proposed study assesses the efficacy of an open source, multimodal artificial intelligence-driven texting tool combined with…
- Trial name
- NCT06569667
- Testing
- PRC supported text + AI driven SDH-enhanced text, AI driven SDH-enhanced text only, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Friends Research Institute, Inc.
Behavior
Evaluation of Link for Equity (Students of Color Population)
The investigators propose to develop and evaluate Link for Equity, a trauma-informed system of care. Link, a system of support for ACE-affected children, is composed of universal school Trauma-Informed Care.
- Trial name
- NCT04026490
- Testing
- Immediate Intervention, Waitlist Intervention
- Where
- United States
- Volunteers
- 518 people
- Sponsor
- University of Minnesota
Colorectal Neoplasms
Understanding Sugar-Sweetened Beverages (SSB) and Colorectal Cancer (CRC)
This study will recruit and consent approximately 120 subjects in the baseline study until the follow-up study recruitment goals of 20 subjects is met.
- Trial name
- SSB and CRC (NCT06669923)
- Testing
- iSIPsmarter Program, Patient Education
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Endometrial Carcinoma
Development of a New Early Detection Test to Reduce Racial Disparities in Endometrial Cancer (EC) Death Rates
This phase I trial investigates the development of a new early detection test to reduce racial disparities in endometrial cancer death rates.
- Trial name
- NCT04474184
- Testing
- Biospecimen Collection, Focus Group, Survey Administration
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Squamous Cell Carcinoma of Head and Neck
Navigation vs Usual Care for Timely Adjuvant Therapy for Patients With Locally Advanced HNSCC
Head and neck cancer squamous cell carcinoma (HNSCC) is a disease with poor survival, especially for African Americans, despite intense treatment including surgery, radiation, and chemotherapy.
- Trial name
- NDURE2 (NCT04030130)
- Testing
- NDURE
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Medical University of South Carolina
Racism
Addressing Microaggressions in Racially Charged Patient-provider Interactions: A Pilot Randomized Trial
Racial bias in medical care is a significant public health issue, with increased focus on microaggressions and the quality of patient-provider interactions.
- Trial name
- NCT04180956
- Testing
- Bias-reduction Intervention
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Washington
Breast Cancer, Cognitive Ability, General
Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer
RATIONALE: Radiation therapy uses high-energy x rays to kill tumor cells. Radiation therapy may cause skin reactions when patients are exposed to high-energy x rays.
- Conditions
- Breast Cancer, Cognitive Ability, General, Fatigue, Pain
- Trial name
- NCT01407770
- Testing
- DNA analysis, gene expression analysis, enzyme-linked immunosorbent assay
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Wake Forest University Health Sciences
Maternal Death
Reducing Racial Disparities in Severe Maternal Morbidity
There is a paucity of research examining the intersection of race, ethnicity, maternal safety bundles, doulas, and maternal outcomes in Black women at increased risk of severe maternal morbidity and mortality.
- Trial name
- NCT04879797
- Testing
- Implementation of Maternal Safety Bundles, Doula Services
- Where
- United States
- Volunteers
- 1,538 people, healthy volunteers welcome
- Sponsor
- Tufts University
Breast Cancer, Colorectal Cancer
Trial of Patient Navigation-Activation
The University of Rochester, Department of Family Medicine, funded by the National Cancer Institute will train community health workers to guide patients through the cancer care system.
- Trial name
- NCT00496678
- Testing
- Navigation, Standard of Care
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Rochester
Chronic Kidney Diseases, High Blood Pressure
Diet and Hypertension Management in African Americans With Chronic Kidney Disease
The purpose of this study is to determine cultural and disease-related barriers and facilitators to following the Dietary Approaches to Stop Hypertension (DASH) dietary pattern among Black Americans with moderate chronic kidney…
- Trial name
- NCT04084574
- Testing
- DASH diet counseling
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Duke University
Blood Pressure, Racial Disparities
The Influence of Beetroot Juice on Racial Disparities in Vascular Health
Black adults are 30% more likely to die from cardiovascular disease (CVD) compared to White adults, and more than half of this racial disparity in cardiovascular mortality may be attributed to the substantially greater prevalence…
- Conditions
- Blood Pressure, Racial Disparities, Cardiovascular Risk Factor
- Trial name
- NCT05132556
- Testing
- Acute Beetroot Juice
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Georgia Southern University