Clinical trials: Racial Disparities
Cancer of Head and Neck
Single-arm Phase II Study of NDURE for Patients With HNC
This study will evaluate whether a new patient navigation intervention can decrease delays starting post-operative radiation therapy after surgery for white and African-American head and neck cancer patients.
- Trial name
- NDURE (NCT03821064)
- Testing
- Patient Navigation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Medical University of South Carolina
HCC, Racial Disparities
Effect of the HCC Liver-Link Intervention
This study is a pilot, multi-center randomized controlled trial testing the HCC Liver-Link intervention, a culturally tailored, multi-level program designed to reduce racial disparities in hepatocellular carcinoma (HCC) care.
- Trial name
- NCT06728293
- Testing
- Liver Link
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Obesity
Peer-Led Healthy Lifestyle Program in Supportive Housing
This goal of this randomized controlled effectiveness trial is to compare the effectiveness of a peer-led health lifestyle intervention (Peer GLB) versus usual care services in supportive housing agencies in New York City and…
- Trial name
- NCT02175641
- Testing
- Peer-Led Group Lifestyle Balance, Usual Care Services
- Where
- United States
- Volunteers
- 314 people
- Sponsor
- Washington University School of Medicine
Sudden Cardiac Death, Heart Failure
Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy
VIVID is a prospective, multicenter, randomized clinical trial in African American patients that will to evaluate: (1) the effect of an educational video on knowledge of sudden cardiac death (SCD) and implantable cardioverter…
- Trial name
- VIVID (NCT02819973)
- Testing
- Educational Video1, Educational Video 2, Usual Care 3
- Where
- 14 sites in United States
- Volunteers
- 343 people
- Sponsor
- Duke University
Breast Cancer, Colorectal Cancer
Trial of Patient Navigation-Activation
The University of Rochester, Department of Family Medicine, funded by the National Cancer Institute will train community health workers to guide patients through the cancer care system.
- Trial name
- NCT00496678
- Testing
- Navigation, Standard of Care
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- University of Rochester
Breast Cancer, Cognitive Ability, General
Genetic Susceptibility to Radiation-Induced Skin Reactions in Racial/Ethnic Groups of Patients With Breast Cancer
RATIONALE: Radiation therapy uses high-energy x rays to kill tumor cells. Radiation therapy may cause skin reactions when patients are exposed to high-energy x rays.
- Conditions
- Breast Cancer, Cognitive Ability, General, Fatigue, Pain
- Trial name
- NCT01407770
- Testing
- DNA analysis, gene expression analysis, enzyme-linked immunosorbent assay
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Wake Forest University Health Sciences
Hypertension, Cardiovascular Diseases
Patient-Portal vs Text-based Hypertension Monitoring Among Black Medicaid/Medicare Patients
The coronavirus disease 2019 (COVID-19) pandemic has uprooted conventional health care delivery for routine ambulatory care, requiring health systems to rapidly adopt telemedicine capabilities.
- Trial name
- NCT05186831
- Testing
- Texting, Online patient portal
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pennsylvania
Breast Cancer, Breast Neoplasms
Integrating Biological, Clinical, and Behavioral Factors to Improve Breast Cancer Outcomes - Carolina Breast Cancer Study
Phase 4 of the Carolina Breast Cancer Study (CBCS4) builds on prior phases that examined molecular and epidemiologic differences in breast cancer types and outcomes.
- Trial name
- NCT07214610
- Testing
- Structured behavioral intervention
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Breast Cancer
Tracking & Feedback Registry to Reduce Breast Cancer Treatment Disparities
Breast cancer is the second most common cause of cancer death in women. Black women are less likely than white women to develop breast cancer but, they are more likely to die of the disease.
- Trial name
- NCT01544374
- Testing
- Tracking & Feedback
- Where
- 11 sites in United States
- Volunteers
- 198 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Genital Herpes Simplex, Maternal Morbidity
Treating Genital Herpes Infection to Reduce Racial Disparities in the Risk of Severe Maternal Morbidity
Severe Maternal Morbidity (SMM) has been associated with maternal mortality, fetal risk, and long-term maternal risk. African American (AA) women are at consistently higher risk than White women.
- Conditions
- Genital Herpes Simplex, Maternal Morbidity, Racial Disparities
- Trial name
- PCORISMM (NCT05429346)
- Where
- United States
- Volunteers
- 339,000 people
- Sponsor
- Kaiser Permanente
Breast Cancer
Reducing Underuse of Early-Stage Breast Cancer Treatment in Minority Communities
The purpose of this study is to determine if a physician-centered intervention will help women with early stage breast cancer receive appropriate treatment.
- Trial name
- NCT00145197
- Testing
- Improving the Delivery of Effective Care to Minorities
- Where
- United States
- Volunteers
- 1,164 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiovascular Diseases, Coronary Disease
Factors Associated With Coronary Heart Disease in African Americans in the Jackson Heart Study
Coronary heart disease (CHD) is the leading cause of deaths that are related to cardiovascular disease in the United States, and Mississippi's CHD mortality rate is the highest in the nation.
- Trial name
- NCT00415415
- Where
- United States
- Volunteers
- 5,302 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Diseases, Hypertension
Mitochondria Oxidative Stress and Vascular Health Study
Cardiovascular diseases (CVDs) are the number one cause of death in America and most of the post-industrial world. Hypertension is a leading risk factor for CVDs including stroke, myocardial infarction, and heart failure.
- Conditions
- Cardiovascular Diseases, Hypertension, Racism, Vascular Diseases
- Trial name
- MOVHS (NCT05561556)
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Auburn University
Racial Disparities, Blood Pressure
The Influence of Mitochondrial-Derived Reactive Oxygen Species on Racial Disparities in Neurovascular Function
Black individuals are at increased cardiovascular disease risk. The central goal of the study is to determine if mitochondrial reactive oxygen species influence blood vessel function and nervous system regulation of blood…
- Conditions
- Racial Disparities, Blood Pressure, Cardiovascular Risk Factor, Renal Function
- Trial name
- MAVHS (NCT04334135)
- Testing
- MitoQ
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Auburn University
Health Care Disparities
Mitigating Racial Disparities in Shared Decision Making in the Intensive Care Unit
This is a non randomized pilot trial aimed to: Test the feasibility of an intervention to support intensive care unit clinicians in conducting shared decision making conversations with families of patients with acute respiratory…
- Trial name
- NCT05710744
- Testing
- Shared decision making tip sheet
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Duke University
Rectal Cancer
Prebiotics in Rectal Cancer
A significant racial disparity in the incidence and mortality of CRC exists in the U.S. with African Americans having CRC incidence and mortality rates that are 20% and 40% higher than the general U.S. population.
- Trial name
- NCT05516641
- Testing
- Soluble Corn Fiber, Maltodextrin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Ochsner Health System
Prostate Cancer
Early Prostate Cancer: Predicting Treatment Response
This study will replicate/validate the risk prediction model developed for the Comparative Effectiveness Analysis of Surgery and Radiation (CEASAR) study in a more diverse patient population to assess generalizability of the…
- Trial name
- NCT03770351
- Where
- 5 sites in United States
- Volunteers
- 693 people
- Sponsor
- University of California, Irvine
Chronic Kidney Disease (CKD), End-Stage Renal Disease (ESRD)
Malnutrition, Diet and Racial Disparities in Chronic Kidney Disease (CKD)
In the United States, African Americans are 3.6 time and Hispanics 1.5 times more likely to suffer from chronic kidney disease and need dialysis treatment for life, when compared to the non-Hispanic Whites.
- Trial name
- MADRAD (NCT01415570)
- Where
- United States
- Volunteers
- 1,050 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Breastfeeding, Infant Death
Support Via Online Social Networks to Promote Safe Infant Care Practices
This study aims to improve adherence to American Academy of Pediatrics safe sleep (SS) recommendations and improve rates of initiation and duration of partial and exclusive breastfeeding (BF); and reduce Black/White disparities…
- Conditions
- Breastfeeding, Infant Death, Sudden Infant Death Syndrome Without Mention of Autopsy
- Trial name
- SUPERSONIC (NCT05767658)
- Testing
- Safe Sleep, Breastfeeding, Early Brain Development and Parent-Child Relationships
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- University of Virginia
Diabetes
Improving Diabetes Care for African Americans
The goal of this study is to investigate methods of improving diabetes care for African Americans in primary care clinics. Primary care clinicians will receive training in the delivery of cross-cultural medicine as well as…
- Trial name
- NCT00436176
- Testing
- Expanded Chronic Care Model
- Where
- United States
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Harvard Vanguard Medical Associates