Clinical trials: Quality of Life Outcomes
Rectal Cancer, Quality of Life
Quality of Life After Transanal Total Mesorectal Excision Compared to Traditional Total Mesorectal Excision
The improvement in prognosis of rectal cancer through modern therapy modalities rises questions regarding quality of life (QoL) and functional outcomes.
- Conditions
- Rectal Cancer, Quality of Life, Functional Outcome, Surgery
- Trial name
- NCT06505863
- Testing
- Transanal total mesorectal excision, Abdominal total mesorectal excision
- Where
- Switzerland
- Volunteers
- 249 people
- Sponsor
- Cantonal Hospital of St. Gallen
Prostatic Hyperplasia, Prostatectomy
Impact of TURP on Quality of Life in Patients With Benign Prostatic Hyperplasia: A Retrospective Study
This study looks at how a common surgery called TURP (Transurethral Resection of the Prostate) affects the quality of life in men with benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate.
- Conditions
- Prostatic Hyperplasia, Prostatectomy, Transurethral Resection of Prostate, Quality of Life
- Trial name
- NCT06995963
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier de Gonesse
Healthy, Psychological Well Being
Survey of Psychological Well-being of Health Care Workers in the Hospital Setting
The psychological well-being of healthcare workers in hospital settings is a topic of growing interest in the scientific literature, given the crucial importance of their role in ensuring high-quality care.
- Conditions
- Healthy, Psychological Well Being, Stress Response, Professional Quality of Life
- Trial name
- IN-VISIBLE (NCT06923436)
- Testing
- Psychological Assessment
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs)
Validation of the EQ-5D-Y-3L and EQ-5D-Y-5L for Paediatric Patients in China
The goal of this observational study is to validate the EQ-5D-Y-3L and EQ-5D-Y-5L in measuring health-related quality of life (HRQoL) for paediatric patients with different health conditions in China.
- Conditions
- Quality of Life (QOL), Patient-Reported Outcome Measures (PROMs), Pneumonia Childhood, Neuroblastoma (NB)
- Trial name
- NCT06873672
- Where
- China
- Volunteers
- 360 people
- Sponsor
- RenJi Hospital
Quality of Life Outcomes, Acoustic Schwannoma
Quality of Life and Decisional Regret in Patients Affected by Acoustic Neuroma
Italian translation and validation study of two different questionnaire (VSQOL and DRS) about quality of life in patient with acoustic schwannoma.
- Trial name
- QOL-DR-NEUROMA (NCT06844461)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Metabolic Syndrome, Fall Risk
Physical Activity and Disability Prevention in Postmenopausal Women
The aim of this clinical study is to examine the impact of physical activity on the physical and mental health of postmenopausal women, with a particular focus on the development of disability.
- Conditions
- Metabolic Syndrome, Fall Risk, Sarcopenia in Elderly, Osteopenia, Osteoporosis
- Trial name
- PADP-Women (NCT06781541)
- Testing
- Nordic walking, Strength training, Bungy Pump Exercises
- Where
- Poland
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Quality of Life, Musculoskeletal Disease
Effectiveness of Routine Measurement of HRQOL
Aim and Objectives: This is an effectiveness-implementation hybrid trial that aims to find out whether the implementation of routine measurement and reporting on the patient's EQ-5D-5L HRQOL data with an electronic platform can…
- Conditions
- Quality of Life, Musculoskeletal Disease, Outcome
- Trial name
- NCT03609762
- Testing
- EQ-5D-5L HRQOL results be available to the attending doctor
- Where
- Hong Kong
- Volunteers
- 1,374 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Peritoneal Dialysis, Hemodialysis, Home
Experiences and Health-related Quality of Life of Informal Caregivers of Dialysis Patients
The goal of this prospective, observational, multicentre cohort study is to assess the trajectory of the experiences (both positive and negative) and health-related quality of life (HRQOL) of informal caregivers of patients who…
- Conditions
- Peritoneal Dialysis, Hemodialysis, Home, Hemodialysis, Quality of Life
- Trial name
- NCT05646615
- Where
- 33 sites in Belgium, Netherlands
- Volunteers
- 202 people, healthy volunteers welcome
- Sponsor
- B.C. van Jaarsveld
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust
Cardiac Surgery, Dexmedetomidine
Dexmedetomidine and Long-term Outcomes in Elderly Patients After Cardiac Surgery
A retrospective study showed that intraoperative dexmedetomidine administration was associated with decreased risk of 1-year mortality after cardiac surgery.
- Conditions
- Cardiac Surgery, Dexmedetomidine, Long-term Outcome, Mortality
- Trial name
- NCT03289325
- Testing
- dexmedetomidine hydrochloride for injection, 0.9% sodium chloride for injection
- Where
- 2 sites in China
- Volunteers
- 285 people
- Sponsor
- Peking University First Hospital
Pegfilgrastim, Bone Pain
Correlation of Timing of Pegfilgrastim Administration and PIBP.
According to the National Comprehensive Cancer Network (NCCN) guidelines, patients receiving high-risk or moderate-risk febrile neutropenia (FN) chemotherapy with at least one risk factor should receive prophylactic granulocyte…
- Conditions
- Pegfilgrastim, Bone Pain, Chemotherapy, Breast Cancer
- Trial name
- NCT05841186
- Testing
- Timing of pegfilgrastim administration
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Guangdong Provincial People's Hospital
Quality of Life, Cardiac Rehabilitation
Patient-Reported Outcome Measures in Cardiac Rehabilitation: Impact on Health Care
Cardiac Rehabilitation (CR) programs are a multidisciplinary process aimed at patient recovery after an acute cardiovascular event or with chronic heart disease, reducing mortality and morbidity, optimising functional capacity…
- Conditions
- Quality of Life, Cardiac Rehabilitation, Patient-Reported Outcome Measures, Rehabilitation Exercise
- Trial name
- PROM_R (NCT06032013)
- Testing
- Cardiac rehabilitation program (PROMs)
- Where
- Portugal
- Volunteers
- 5 people
- Sponsor
- José Manuel Afonso Moreira
Gastrointestinal Function, Quality of Life
A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis
This retrospective study aims to compare the surgical and pregnancy outcomes of disc and segmental resection for rectal DIE through a single-center retrospective analysis, to summarize clinical experience, and to explore the…
- Conditions
- Gastrointestinal Function, Quality of Life, Pregnancy Outcomes
- Trial name
- NCT06254716
- Testing
- disc resection, segmental resection
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fudan University
Pancreatic Cancer, Patient Reported Outcome Measures
Patient Reported Outcomes Measures to Predict Pancreatic Surgery Outcomes
This is a prospective single-center observational study with the mail objective to identify specific subgroups of patients planned for pancreatic resection, at high risk for postoperative morbidity and impaired recovery through…
- Conditions
- Pancreatic Cancer, Patient Reported Outcome Measures, Quality of Life, Pancreatectomy
- Trial name
- PRO-PANC1 (NCT04431076)
- Where
- Italy
- Volunteers
- 560 people
- Sponsor
- Massimo Falconi
Covid19, Patient Reported Outcome Measures, Quality of Life
Development of an International COVID-19 Specific Quality of Life Questionnaire, Phase III. The OSLO COVID-19 QLQ
Purpose: to develop an international validated patient-reported outcome measure for COVID-19 patients according to international guidelines.
- Trial name
- NCT04740372
- Testing
- No intervention. Method study. Psychometric testing
- Where
- Norway
- Volunteers
- 371 people
- Sponsor
- Oslo University Hospital
Rehabilitation, Exercise Therapy
Rehabiliation Using HUBER 360 to Reduce the Risk of Falls
Aim: The aim of the present study was to analyse the effects of training performed on a rotating, motorised platform (the Huber/SpineForce device from LPG Systems, Valence, France) intended to reduce the risk of falls.
- Conditions
- Rehabilitation, Exercise Therapy, Treatment Outcome, Quality of Life
- Trial name
- HUBER-FALLS (NCT04687293)
- Testing
- HUBER (LPG Systems, France)
- Where
- Belgium
- Volunteers
- 32 people
- Sponsor
- University of Liege
Breast Neoplasm, Cosmetic Outcome
Aspects of Breast-conserving Surgery
Prospective study of cosmetic outcome and quality of life for women undergoing breast cancer surgery using patient a reported outcome measure (BREAST-Q) and a computer program validated to assess cosmetic outcomes after breast…
- Conditions
- Breast Neoplasm, Cosmetic Outcome, Quality of Life
- Trial name
- NCT04227613
- Where
- Sweden
- Volunteers
- 351 people
- Sponsor
- Lund University
Cardiac Valve Disease, Paravalvular Aortic Regurgitation
European Multicentre Registry of Percutaneous Paravalvular Leak Closure
Paraprosthetic cardiac valve leaks are a progressive complication after after surgical or percutaneous heart valve replacement. These leaks can lead to heart failure and/or life-threatening hemolysis.
- Conditions
- Cardiac Valve Disease, Paravalvular Aortic Regurgitation, Paravalvular Mitral Regurgitation, Paravalvular Leak
- Trial name
- EuroPVL (NCT05506293)
- Testing
- percutaneous paravalvular leak closure
- Where
- 33 sites in Belgium, Czechia and 10 more
- Volunteers
- 400 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Quality of Life, Long-term Outcomes
Quality of Life and Long-term Outcomes After Hospitalization for COVID-19
The present study aims to assess the determinants of health-related quality of life and long-term outcomes among survivors of hospitalization for Covid-19 in Brazil.
- Conditions
- Quality of Life, Long-term Outcomes, Coronavirus Infection
- Trial name
- NCT04376658
- Testing
- COVID-19 Severity
- Where
- Brazil
- Volunteers
- 1,508 people
- Sponsor
- Hospital Moinhos de Vento
Cachexia, Neoplasms
Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms
Muscle mass loss is a common adverse effect of cancer. Muscle mass loss occurs with or without reduction in body weight. Cancer cachexia (CC) is the involuntary loss of body weight of >5% within 6 months and it occurs in 50-80%…
- Conditions
- Cachexia, Neoplasms, Exercise, Metabolism
- Trial name
- PANACEA (NCT05307367)
- Testing
- Exercise training
- Where
- Denmark
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen