Clinical trials: Pulp Disease, Dental
Pulpitis
Evaluation of Pulpotomy Using Two Different Agents in Mature Anterior Teeth With Pulpitis
the study will evaluate the clinical and radiological success of mature permanent anterior teeth pulpotomy in children and adolescents with signs of pulpitis using two different Biomimetic materials (NeoPutty® and Biodentine™) as…
- Trial name
- NCT06468085
- Testing
- premixed Bioceramic NeoPUTTY®, Biodentine™, Root canal treatment
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulp Necroses
Post Operative Pain Assessment After Pulpectomy of Primary Molars With Two Different Rotary Systems
Evaluation of post operative pain after pulpectomy procedures for primary molars with irreversible pulp damage and without periapical radulicency using two different systems (One shape file ( ratation movemont) and wave one gold…
- Trial name
- NCT05057325
- Testing
- Pulpectomy using single file system ( One Shape file), Pulpectomy using single file system ( WaveOne Gold file)
- Where
- Egypt
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Minia University
Dental Pulp Exposure, Postoperative Pain
Diode Laser-Assisted Direct Pulp Capping Trial
This randomized controlled clinical trial evaluates whether adjunctive 808-nm diode laser therapy after direct pulp capping reduces postoperative pain and dentin hypersensitivity compared with conventional Biodentine treatment.
- Conditions
- Dental Pulp Exposure, Postoperative Pain, Dentin Hypersensitivity
- Trial name
- NCT07593508
- Testing
- Biodentine, 808-nm Diode Laser
- Where
- Vietnam
- Volunteers
- 56 people
- Sponsor
- Hue University of Medicine and Pharmacy
Dental Caries
Indirect Pulp Capping Versus Hall Crown Technique for the Management of Deep Dentinal Caries of Primary Molars.
This is a randomized clinical trial that aims to compare the clinical and radiographic success of Hall technique (HT) versus Indirect pulp capping (IPC) for the management of deep dentinal caries in primary molars and to compare…
- Trial name
- NCT07136155
- Testing
- Hall Technique, Indirect pulp capping
- Where
- Jordan
- Volunteers
- 120 people
- Sponsor
- King Abdullah University Hospital
Periodontitis
Allogeneic Dental Pulp Stem Cells for the Treatment of Periodontitis
The overall objective of this study is to evaluate the safety and efficacy of allogeneic human dental pulp stem cells (DPSCs) injected for the treatment of chronic periodontitis in humans.
- Trial name
- NCT07574840
- Testing
- Allogeneic Dental Pulp Stem Cells for the Treatment of Periodontitis
- Volunteers
- 30 people
- Sponsor
- The First Affiliated Hospital of Xinxiang Medical College
Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth
One Year Clinical Evaluation of Milled BioHPP Polyetheretherketone (PEEK)-Based Versus Metal Ceramic Single Crowns
Although the metal-ceramic system is still widely used to fabricate crowns and fixed partial dentures and is considered as the standard treatment in dentistry, aesthetic concerns have stimulated the development of new dental…
- Conditions
- Single Posterior Crowns, Badly Decayed Teeth, Teeth Restored With Large Filling Restorations or Endodontically Treated Teeth, Malformed Teeth, Malposed Teeth (Tilted, Over-erupted, Rotated, Etc.) or Spacing Between Posterior Teeth
- Trial name
- NCT03685513
- Testing
- BioHPP PEEK-based single posterior crowns, Metal ceramic single posterior crowns
- Volunteers
- 46 people
- Sponsor
- Cairo University
Endodontically Treated Teeth
Postoperative Pain After İntracanal Procedures
Aim: The aim of this study is to investigate the effects of different irrigation activation systems on pain after endodontic treatment in molar teeth with irreversible pulpitis.Post-operative pain values of the participants will…
- Trial name
- NCT04892355
- Testing
- Root canal irrigation
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Periapical Periodontitis
Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration.
To compare the dental survival in a period of one year of mature permanent teeth with apical lesion following the administration of encapsulated Mesenchymal Stem Cells under a regenerative endodontic procedure and a conventional…
- Trial name
- RanoKure (NCT03102879)
- Testing
- Regenerative Endodontic Procedure, Conventional Root Canal Treatment
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Universidad de los Andes, Chile
Pulp Necroses, Tooth, Nonvital
Microbiological Evaluation of Single Versus Multiple Visits Regeneration Using MALDI-TOF Mass Spectrometry
Aim of the study is to assess canal disinfection using matrix assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) in single visit and multiple visit regeneration protocols, and to assess clinical…
- Trial name
- NCT04533074
- Testing
- Single-visit regeneration protocol, Multiple-visits regeneration protocol
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Nourhan M.Aly
Endodontic Disease, Endodontic Re-treatment Failure
Guided Versus Conventional Periapical Endodontic Surgery
This study is to compare the clinical and radiographic outcomes after guided periapical endodontic surgery versus conventional endodontic surgery.
- Trial name
- NCT04133181
- Testing
- 3D guide, Mock guide
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Canal Therapy
Clinical Applicability of PBSCIMMO as a Single Material in Endodontic Obturations
A randomized, interventional, prospective, unicentric clinical study, 86 patients will be submitted to endodontic treatment of necrotic teeth.
- Trial name
- PBSCIMMO (NCT03514264)
- Testing
- Gutta Percha and AHPLUS cement (group A), PBS CIMMO cement (group B)
- Where
- Brazil
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade do Vale do Sapucai
Pulp Necrosis, Apical Periodontitis
Comparing Amla (Emblica Officinalis) and 3% Sodium Hypochlorite Against Enterococcus Faecalis in Root Canal Treatment.
Bacteria inside the root canal are a major cause of tooth infections. If they are not completely removed, the infection may continue even after root canal treatment.
- Trial name
- NCT07688005
- Testing
- Sodium Hypochlorite 3% Solution, Emblica officinalis Solution
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Tooth Loss
The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation
The purpose of this study is to examine and compare the effects of autogenous dental pulp tissue on bone formation in the extraction sockets as compared to commonly used particulate bone graft.
- Trial name
- NCT03943849
- Testing
- Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Pulp Necroses
Histopathological Evaluation of the Periodontal Ligament Subjected to Laser Ablation.
Laser Ablation therapy (LA) using an 810nm diode laser and Indocyanine Green (ICG) solution, which efficiently absorbs laser energy and increases the effectiveness of tissue removal.
- Trial name
- NCT06173648
- Testing
- Laser and ICG solution.
- Where
- Brazil
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- CAO Group, Inc.
Necrotic Pulp
Rosmarinus Officinalis Versus 2.5%Sodium Hypochlorite as Root Canal Irrigants
To measure the Effect of Rosmarinus Officinalis versus 2.5%Sodium Hypochlorite as Root canal Irrigants on the Intensity of post-operative pain and Bacterial Reduction in asymptomatic necrotic Mandibular premolars.
- Trial name
- NCT05289843
- Testing
- Rosmarinus Officinallis
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Disease, Dental
Effect of Different Bioactive Restorative Materials and Techniques on Pulpal Condition
Restorative materials play a crucial role in dental treatments, particularly in managing tooth decay and restoring damaged teeth.
- Trial name
- NCT07715383
- Testing
- Bioactive Restorative Materials
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Dina Ashraf
Pulp Necrosis
Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth
the object of this study is to evaluate clinically and radiographically the effect of using Biodentine and Mineral Trioxide Aggregate as coronal plug materials in revascularization of non-vital immature teeth
- Trial name
- NCT03589560
- Testing
- Biodentine, Mineral Trioxide Aggregate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Deep Caries, Pulp Exposure, Dental
Evaluation of Conservative Management of Teeth With Deep Cavitated Carious Lesions
The goal of this clinical trial is to compare postoperative pain of calcium silicate cement and resin-based tricalcium silicate (TheraCal LC) versus chemically Cured Glass Ionomer cement (FujiXI) in conservative management of…
- Trial name
- NCT06171776
- Testing
- RetroMTA, TheraCal, Fuji IX
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endodontically Treated Teeth, Nonvital Teeth
Clinical Comparison of Lithium Disilicate and 3D-Printed Resin Endocrowns
This randomized controlled clinical trial aims to compare the clinical performance of CAD/CAM lithium disilicate (IPS e.max CAD) and 3D-printed resin (BEGO VarseoSmile TriniQ) endocrown restorations in endodontically treated…
- Conditions
- Endodontically Treated Teeth, Nonvital Teeth, Restoration of Endodontically Treated Posterior Teeth
- Trial name
- NCT07874906
- Testing
- IPS e.max CAD Lithium Disilicate Endocrown, BEGO VarseoSmile TriniQ Resin Endocrown
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medipol University
Pulpitis
Post-operative Pain in 2Shape Versus Protaper Next Rotary Systems
Pain after endodontic treatment is considered the most disturbing problem facing both the patient and the dentist especially in cases of symptomatic pulpitis as the patient is expecting to relief the pain that already…
- Trial name
- NCT03694743
- Testing
- 2Shape rotary system
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cairo University