Clinical trials: Psychotherapy
Borderline Personality Disorder
Efficacy of Transference-Focused Psychotherapy for Borderline Personality Disorder
The purpose of this study is to find out whether Transference-Focused Psychotherapy (TFP) is effective in the treatment of Borderline Personality Disorder.
- Trial name
- NCT00714311
- Testing
- Transference-Focused Psychotherapy, treatment by experienced community psychotherapists
- Where
- 2 sites in Austria, Germany
- Volunteers
- 104 people
- Sponsor
- University Hospital Muenster
PTSD
Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD
The goal of this clinical trial is to learn if MDMA-assisted therapy is effective in U.S. military veterans with at least moderate chronic PTSD.
- Trial name
- MPVA6 (NCT04784143)
- Testing
- Midomafetamine, Psychotherapy
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Resilient Pharmaceuticals
Behavior, Anxiety
Effects of Oxytocin on Behavior and Physiology in a Psychotherapy Setting
Subjects-currently in outpatient mental health care--will participate in 2 psychotherapy sessions, one with oxytocin spray and one with placebo spray. Sessions will be videotaped, and cortisol and heart rate will be measured.
- Trial name
- OT-PT (NCT01081249)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- MacDonald, Kai, M.D.
Loneliness, Social Isolation
Engage Psychotherapy to Promote Connectedness in Caregivers
The Engage Coaching Project is a Stage 1 intervention development study. This study asks: "what behavioral strategies are needed to help socially disconnected caregivers with significant barriers to increasing connectedness?"…
- Conditions
- Loneliness, Social Isolation, Caregiver Burnout
- Trial name
- NCT04176601
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Major Depressive Disorder
Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression
This study focuses on treating adolescents with depression. The study has two main purposes. The first is to compare a new form of therapy for depression called Behavioral Activation (BA) to the antidepressant medication…
- Trial name
- NCT01740726
- Testing
- Behavioral Activation, Fluoxetine
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Mental Health Issue, HIV
Single Session Narrative Therapy Study
This pilot research study will provide timely access to behavioral health services through the provision of a single-session narrative therapy intervention.
- Conditions
- Mental Health Issue, HIV, Substance Use
- Trial name
- NCT06479980
- Testing
- Single Session Narrative Therapy
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Washington
Obstructive Sleep Apnea, PTSD
Cognitive Behavioral Therapy to Increase CPAP Adherence in Veterans With PTSD
Approximately 20 million Americans suffer from Obstructive Sleep Apnea (OSA) creating risks for major health problems, including dementia, heart attack, and stroke.
- Conditions
- Obstructive Sleep Apnea, PTSD, Posttraumatic Stress Disorder
- Trial name
- NCT02641496
- Testing
- CBT-OSA, Sleep Education
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicide, Suicidal Ideation
Brief Interventions for Short-Term Suicide Risk Reduction in Military Populations
The purpose of the proposed study is to identify the most effective brief interventions for reducing short-term risk for suicide attempts in "real world" military triage settings, and to identify potential mechanisms of change…
- Trial name
- BISSR (NCT02042131)
- Testing
- Treatment As Usual (TAU), Standard Crisis Response Plan (S-CRP), Enhanced Crisis Response Plan (E-CRP)
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- University of Utah
Depression
Augmenting Antidepressant Treatment With Interpersonal Psychotherapy for Treating Late-life Depression
This study will determine whether adding interpersonal psychotherapy to treatment with the antidepressant escitalopram will be more effective in reducing symptoms of depression than antidepressant medication alone.
- Trial name
- NCT00177294
- Testing
- Escitalopram, Interpersonal Psychotherapy, Clinical Monitoring
- Where
- United States
- Volunteers
- 319 people
- Sponsor
- University of Pittsburgh
Posttraumatic Stress Disorder
Teaching Loved Ones to Help Veterans Optimize Their PTSD Care and Healing
PTSD occurs in as many as 17% of US military Veterans and is associated with a host of negative, long-term consequences to the individual, their families, and society at large.
- Trial name
- NCT04241094
- Testing
- Loved one assisted treatment
- Where
- 3 sites in United States
- Volunteers
- 28 people
- Sponsor
- VA Office of Research and Development
Posttraumatic Stress Disorder
MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder
The goal of this clinical trial is to compare MDMA-assisted therapy to placebo with therapy in people with chronic, treatment-resistant posttraumatic stress disorder (PTSD).
- Trial name
- NCT00090064
- Testing
- Midomafetamine HCl, Therapy
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Resilient Pharmaceuticals
Bipolar Disorder, Depression
Acute Psychotherapy for Bipolar II Depression
This proposed study is designed to compare the efficacy of interpersonal and social rhythm therapy (IPSRT) alone to IPSRT plus medication as an acute treatment for bipolar II depression.
- Trial name
- NCT01133821
- Testing
- IPSRT plus quetiapine
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Holly Swartz
Depression
Cognitive Therapy for Recurrent Depression
This study determined the effectiveness of continuation phase cognitive therapy versus antidepressant medication in preventing relapse of depression in people with recurrent depression.
- Trial name
- NCT00118404
- Testing
- Continuation phase cognitive therapy, Continuation phase fluoxetine, Acute phase cognitive therapy
- Where
- 2 sites in United States
- Volunteers
- 523 people
- Sponsor
- University of Texas Southwestern Medical Center
Psychological Feedback
The STIC Norway RCT Study: Using Feedback in Psychotherapy.
Feedback in psychotherapy involves clients monitoring therapy process and progress, and on a frequent basis clients register these data into online questionnaires.
- Trial name
- STICNorway (NCT01873742)
- Testing
- STIC feedback system
- Where
- 3 sites in Norway
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- Modum Bad
Depression
Managing Cancer and Living Meaningfully (CALM) Therapy in Individuals Diagnosed With a Primary Brain Tumor
Background: Psychological distress affects many people diagnosed with a primary central nervous system tumor (CNST). Distress can include negative feelings such as anger, fear, or sadness.
- Trial name
- NCT04852302
- Testing
- Cancer and Living Meaningfully (CALM) Therapy
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- National Cancer Institute (NCI)
Distress, Anxiety
Acceptance and Commitment Therapy (ACT) for OEF/OIF Veterans
This trial compares two psychotherapies, Acceptance and Commitment Therapy (ACT) and Present Centered Therapy (PCT), for veterans of the conflicts in Iraq and Afghanistan.
- Conditions
- Distress, Anxiety, Depression, Postconcussive Symptoms
- Trial name
- NCT01253044
- Testing
- Acceptance and Commitment Therapy, Present Centered Therapy
- Where
- 6 sites in United States
- Volunteers
- 160 people
- Sponsor
- Veterans Medical Research Foundation
PTSD
Open Label Study of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study
The goal of this clinical trial is to learn if MDMA-assisted therapy is safe and effective in people diagnosed with at least severe PTSD.
- Trial name
- NCT04030169
- Testing
- Midomafetamine HCl
- Where
- 6 sites in Czechia, Germany and 3 more
- Volunteers
- 21 people
- Sponsor
- MAPS Europe B.V.
Chronic Pain
Digital Therapeutic for Chronic Pain Feasibility Study
The investigators will conduct a 2-arm randomized control feasibility study to evaluate: 1) the feasibility of using the mobile app and an optional activity tracker, 2) the feasibility of conducting a 2-arm trial, and 3) estimate…
- Trial name
- NCT06000007
- Testing
- 2Morrow Chronic Pain Self-Management Program - digital therapeutic mobile app, Treatment as usual
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Washington
Post-Traumatic Stress Disorder
Effectiveness of Three Different Psychotherapies for Chronic Post-Traumatic Stress Disorder
This study will examine whether interpersonal psychotherapy is as effective in treating post-traumatic stress disorder as the established therapies of prolonged exposure and relaxation.
- Trial name
- NCT00739765
- Testing
- Interpersonal Psychotherapy, Prolonged Exposure Therapy, Relaxation Therapy
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- New York State Psychiatric Institute
Smoking Cessation
Positive Psychotherapy for Smoking Cessation Enhanced With Text Messaging: A Randomized Controlled Trial
Positive Psychotherapy for Smoking Cessation (PPT-S) addresses an array of risk factors for poor smoking outcomes (low positive affect, depressive symptoms, and cynical cognitions), while also providing skills that may buffer…
- Trial name
- NCT02997657
- Testing
- Positive Psychotherapy, Standard smoking cessation counseling
- Where
- 2 sites in United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- Brown University