Clinical trials: Psychological Distress
Distress, Psychological
Effect of Mindfulness-Based Protocols on Psychological Parameters and Biological Markers in Populations Exposed to Conditions of Persistent Distress
The goal of this clinical trial is to learn if a Mindfulness-Based Stress Reduction (MBSR) training can improve the mental health and well-being of healthcare professionals (HCPs) exposed to prolonged severe stress conditions.
- Trial name
- NCT07129057
- Testing
- MBSR program
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Self-Criticism, Psychological Distress
Interplay of Self-Criticism and Symptom Severity Over the Course of In-patient Psychotherapeutic Treatment
The purpose of this study is to assess the interplay between self-criticism and symptom severity in patients undergoing psychotherapeutic treatment.
- Conditions
- Self-Criticism, Psychological Distress, In-Patient Treatment
- Trial name
- InSeCur (NCT05120453)
- Volunteers
- 2,778 people
- Sponsor
- University Hospital Heidelberg
Cardiovascular Disease, Psychological Distress
Evaluation of a Personcentered Internet-based CBT Program for Stress, Anxiety and Depressive Symptoms in Patients With Cardiovascular Disease
To evaluate a nine-week adaptable and person-centred I-CBT program that can be directed towards stress, anxiety and depressive symptoms in persons with CVD.
- Trial name
- NCT04726722
- Testing
- internet-based cognitive behavioral theraphy
- Where
- Sweden
- Volunteers
- 215 people
- Sponsor
- University Hospital, Linkoeping
Congestive Heart Failure (CHF)
Group Psychotherapy Among Congestive Heart Failure Patients
This study will examine the efficacy of group therapy utilizing the Existential Approach in heart failure patients when compared to a control group of patients who are waiting for the same group treatment.
- Trial name
- NCT01414439
- Testing
- Existential Group Therapy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Meir Medical Center
Mental Health
Surgeons' Mental Distress and Risks After Severe Complications Following Emergency Surgery
Surgeons experience higher levels of work stress, even under normal circumstances. Many can suffer from substantial levels of mental health issues, especially when faced with severe complications.
- Trial name
- NCT05864443
- Testing
- Severe complications following emergency surgery
- Volunteers
- 2,500 people
- Sponsor
- Shanghai Zhongshan Hospital
Feeding and Eating Disorders
Fear, Gastrointestinal Distress, and Interoception: Physiological and Psychological Mechanisms in Eating Disorders
The proposed study tests fear, gut peptide response, and perceptions of fullness as causes of gastrointestinal distress and eating disorder maintenance.
- Trial name
- NCT05382702
- Testing
- Test meal description changed
- Where
- United States
- Volunteers
- 133 people
- Sponsor
- Ohio University
University Students, Psychological Intervention
Counselling Intervention for College Students Experienced Psychological Distress
The goal of this clinical trial is to evaluate mental health and academic motivation in university students asking help to university counselling service (UCS) in Southern Italy before anf after four weekly psychological…
- Conditions
- University Students, Psychological Intervention, Psychological Distress
- Trial name
- TRESPASS (NCT06333444)
- Testing
- four weekly psychological counselling intervention
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Campania Luigi Vanvitelli
Cardiac Surgery
Online Cognitive Behavioral Therapy for Rehabilitation After Cardiac Surgery
The purpose of the present pilot study is to evaluate the feasibility and potential efficacy of a brief, internet-delivered CBT protocol provided early following cardiac surgery.
- Trial name
- TRACS (NCT05727865)
- Testing
- Online CBT following cardiac surgery
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet
CASA Intervention, Usual Care
Beyond Psychological Distress: Implementation of a Dyadic Behavioral Intervention Targeting Neuroendocrine and mRNA Translational Pathways in Late-Stage Breast Cancer
Specific Aim 1: Determine the effect of CASA on psychological distress (primary outcome) and on neuroendocrine, inflammatory, and translational control measures (secondary and exploratory outcomes) in LSBC-PR patients and…
- Trial name
- Beyond ID (NCT07828288)
- Testing
- The Caregivers-Patients Support to Cope with Advanced Cancer (CASA) is a five-session, manualized, meaning-centered psychotherapy developed for Puerto Rican patients and caregivers coping with advance, Control Condition. Includes CBT as the primary treatment approach for cancer patients and it is considered the usual care approach in these clinics, as well as one of the primar
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Interpersonal Functioning, Psychological Distress
Assessing the Mechanism of Change of Functional Analytic Psychotherapy
This study seeks to assess the mechanisms of change of Functional Analytic Psychotherapy (FAP). FAP is a process-outcome psychotherapy that focuses on the therapeutic relationship, providing services to participants presenting…
- Trial name
- FAP (NCT03562962)
- Testing
- Functional Analytic Psychotherapy
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno
Depressive Symptoms, Psychological Distress
Internet-based Intervention for Enhancing the Psychological Well-being of Elderly Caregivers
This study will examine whether an Internet-based Acceptance and Commitment Therapy (ACT) intervention is effective, firstly, on reducing depressive symptoms, and, secondly, on improving well-being of elderly family caregivers.
- Conditions
- Depressive Symptoms, Psychological Distress, Quality of Life
- Trial name
- CareACT (NCT03391596)
- Testing
- Internet-based ACT intervention, Standardized rehabilitation, Support by voluntary caregiver associations
- Where
- Finland
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- The Gerocenter Foundation for Research and Development
PreDiabetes, Diabetes Mellitus, Type 2
Acceptance and Commitment Therapy Principles for Diabetes Prevention
The investigators will evaluate whether a brief intervention (i.e. a workbook and video presenting educational information and activities materials for diabetes prevention) that incorporates principles drawn from focused…
- Conditions
- PreDiabetes, Diabetes Mellitus, Type 2, Diabetes, Diabetes type2
- Trial name
- NCT05260983
- Testing
- Diabetes Prevention Education and Acceptance and Commitment Therapy, Diabetes Prevention Education Only
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Oregon
HCC - Hepatocellular Carcinoma, Psychological Distress
The Impact of Emotional Stress on Immunotherapy Outcomes in Liver Cancer Patients: A Multi-Cohort Study
The goal of this observational study is to learn if emotional distress affects how well liver cancer treatment works in people receiving immunotherapy. Emotional distress means feeling anxious or depressed.
- Conditions
- HCC - Hepatocellular Carcinoma, Psychological Distress, Immune Checkpoint Inhibitors (ICIs), Cancer, Treatment-Related
- Trial name
- SOLACE (NCT07141056)
- Testing
- Psychological Stress Status
- Where
- 5 sites in China
- Volunteers
- 700 people
- Sponsor
- Guilin Medical University, China
Critical Illness, Family Members
Addressing Palliative Care Needs Among Intensive Care Unit Family Members
The quality of palliative care is highly variable for many patients treated in intensive care units (ICUs) and their family members.
- Conditions
- Critical Illness, Family Members, Psychological Distress, Informal Caregivers
- Trial name
- ICUconnect (NCT03506438)
- Testing
- Needs-focused mobile app, Usual care
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Duke University
Post-traumatic Stress Disorder, Moral Injury
General Psychological Distress, PTSD, and Co-Morbidities in Healthcare Workers Consequent to Occupational Trauma
It is expected that large numbers of healthcare workers experience a broad range of psychological reactions and symptoms including anxiety, depression, moral distress, and trauma symptoms that will cause both significant…
- Trial name
- NCT04626050
- Testing
- Medical Music, Narrative Writing, Prolonged Exposure Therapy
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Psychological Distress, Cancer
Web-based Stress Management for Newly Diagnosed Cancer Patients (STREAM-1)
Many cancer patients experience their illness as substantial psychological burden. About half of the cancer patients suffer from severe stress symptoms and around one third of the patients fulfill the criteria for a clinically…
- Trial name
- STREAM (NCT02289014)
- Testing
- online stress Management program
- Where
- Switzerland
- Volunteers
- 129 people
- Sponsor
- University Hospital, Basel, Switzerland
Stress, Psychological, Occupational, Stress, Psychological
Self-Help Plus (SH+) for Stress Reduction in Social Service Workers: A Pilot RCT
This is a two-arm, stratified cluster-randomized controlled pilot trial evaluating the feasibility and preliminary effectiveness of the World Health Organization's Self-Help Plus (SH+) intervention for stress reduction among…
- Conditions
- Stress, Psychological, Occupational, Stress, Psychological, Psychological Distress, Burnout, Professional
- Trial name
- NCT07644949
- Testing
- Self-Help Plus (SH+), Enhanced Care as Usual (ECAU)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Psychological Distress, Pregnancy Related
Mindful Moms: Mechanisms of Mindfulness-based Cognitive Therapy During Pregnancy and Postpartum
The proposed study seeks to elucidate the mechanisms underlying Mindfulness-Based Cognitive Therapy in pregnancy to improve understanding of how and why this treatment modality enhances well-being, which can then be leveraged to…
- Conditions
- Psychological Distress, Pregnancy Related, Postpartum Blues, Postpartum Depression
- Trial name
- NCT05137925
- Testing
- Mindfulness-Based Cognitive Therapy (MBCT), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Exercise, Renal Dialysis
Exercise Effect on Psychological Distress of Patients Undergoing Hemodialysis at Al-Suwaiq Dialysis Center
The aim to investigate the level of psychological distress on patients undergoing hemodialysis at Al-Suwaiq Renal dialysis center as well as to explore the effectiveness of home-based exercise method in reducing such…
- Conditions
- Exercise, Renal Dialysis, Anxiety, Depression
- Trial name
- NCT07083843
- Testing
- Exercise, Standard medical treatment
- Where
- Oman
- Volunteers
- 54 people
- Sponsor
- Oman Ministry of Health
Psychological Distress, Mindfulness Skills
Mindfulness Training and Respiration Biosignal Feedback - Study 2
The goal of this research is to test usability and user satisfaction with a new breathing feature on the meditation app, Equa, to help young adults who are distressed, understand their physiological responses and mindfulness…
- Conditions
- Psychological Distress, Mindfulness Skills, Usability Satisfaction
- Trial name
- NCT07136948
- Testing
- Mindfulness Meditation, Mindfulness Meditation with Respiration Feedback Chart and Predictive Mindfulness Skill Scores
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Equa Health