Clinical trials: Psychiatric Problem
Genetic Predisposition to Disease
Breast Cancer Risk After Diagnostic Gene Sequencing
Study of the psychological impact of breast cancer risk communication in Cancer Genetics based on the personalized estimation of the BOADICEA V5/PLUS model ("Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation…
- Trial name
- BRIDGEScohort2 (NCT04145817)
- Testing
- BRIDGES gene panel testing, Breast cancer risk polygenic risk score (PRS), Questionnaires
- Where
- 2 sites in France, Germany
- Volunteers
- 405 people
- Sponsor
- Institut Curie
Schizophrenia
Mental Health During the Whole Life Cycle of Community Patients With Schizophrenia
Schizophrenia is one of the components of severe mental disorders. It has the characteristics of prolonged course, low cure rate, high recurrence rate and high disability rate.
- Trial name
- NCT05159349
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Shanghai Mental Health Center
Inflammatory Bowel Diseases
Mindfulness-based Cognitive Therapy for Patients With Inflammatory Bowel Disease
Considering the limited availability of psychosocial interventions for IBD, this study aims to investigate MBCT as an adjunctive treatment to treatment as usual to reduce psychological stress and improve sleep quality/regularity…
- Trial name
- NCT04646785
- Testing
- Mindfulness-based cognitive therapy + TAU, Treatment as usual (TAU)
- Where
- 4 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Radboud University Medical Center
Vulvodynia, Dyspareunia
Therapy to Prevent Sexual Pain in Breast Cancer Survivors
The purpose of this protocol is to determine whether pain with sexual intercourse can be reduced in menopausal, breast cancer survivors and to evaluate the effectiveness of a non-hormonal therapy (Lidocaine Liquid) vs.
- Conditions
- Vulvodynia, Dyspareunia, Breast Cancer, Menopause
- Trial name
- NCT01539317
- Testing
- Topical liquid lidocaine, Topical saline
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- OHSU Knight Cancer Institute
Depression, Family Dynamics
The Mental Health Effects of a Mindfulness App in Parents of a Child With Medical Complexity
The number of children with special health care needs (CSHCN) in the US is nearly 20% of children representing approximately 14.6 million children nationally.
- Conditions
- Depression, Family Dynamics, Stress, Psychological, Chronic Illness
- Trial name
- NCT05925868
- Testing
- mindfulness app
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Boise State University
Generalised Anxiety Disorder
Trial of Sertraline Versus Cognitive Behaviour Therapy for Generalised Anxiety
Generalised Anxiety Disorder (GAD) is common, causes unpleasant symptoms and impairs people's functioning. It is often chronic and may be accompanied by depression and other anxiety disorders.
- Trial name
- ToSCA (NCT02347033)
- Testing
- Sertraline, Cognitive Behavioural Therapy
- Where
- United Kingdom
- Volunteers
- 5 people
- Sponsor
- University College, London
Psychological Stress, Sleep Disturbance
Sleep More, Stress Less: 90-Day Trial of Neuralli Mood
This decentralized, single-arm study evaluates the effects of 90 days of daily Neuralli Mood supplementation on perceived stress, sleep disturbance, mood, anxiety, depressive symptoms, happiness, and occupational burnout in…
- Conditions
- Psychological Stress, Sleep Disturbance, Anxiety Symptoms, Depressive Symptoms
- Trial name
- NM90 (NCT07717385)
- Testing
- Neuralli Mood
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Efforia, Inc
Bereavement
Bereaved Young Adults Study
Bereaved adolescents and emerging adults are at risk for developing psychological disorders and complicated grief. Clinical grief interventions and conventional wisdom reflect an implicit assumption that sharing and expressing…
- Trial name
- NCT05352243
- Testing
- Expressive Disclosure, Expressive Helping, Fact-Writing
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Postpartum Hemorrhage, Postpartum Women
Prevalence of Psychological Disorders After Immediate Postpartum Hemorrhage
The objective of this cross-sectional study is to assess the prevalence of depression at 2 months, 6 months, and 1 year postpartum in women who had an immediate postpartum hemorrhage (immediate PPH defined as blood loss ≥ 500 mL…
- Conditions
- Postpartum Hemorrhage, Postpartum Women, Postpartum Depression, Postpartum Stress
- Trial name
- PSYCHE (NCT03120208)
- Testing
- • The Edinburgh postnatal depression scale (EPDS), validated in French, with a discrimination threshold ≥ 11., The GAD-7 with a discrimination threshold ≥10., • Spielberger's State-Trait anxiety inventory, Form Y (validated in French), with a STAI (form Y-A) discrimination threshold ≥ 46
- Where
- France
- Volunteers
- 1,298 people
- Sponsor
- University Hospital, Clermont-Ferrand
Ischemic Heart Disease (IHD), Anxiety
Online Personalized Psychological Intervention for Patients With Heart Disease and Depression or Anxiety (MY-CHOICE)
The goal of this feasibility study is to assess if the personalised online psychological intervention MY-CHOICE is acceptable to adults with ischemic heart disease and anxiety or depression.
- Conditions
- Ischemic Heart Disease (IHD), Anxiety, Depression
- Trial name
- MY-CHOICE (NCT07569458)
- Testing
- Online psychological therapy
- Where
- 3 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- University of Southern Denmark
Mental Wellbeing
A 12-week Feasibility Trial of a Mental Health Breakfast Show Wakey
The aim of Wakey! is to increase access to wellbeing support to lower socio-economic groups who have traditionally been excluded from the design and evaluation of digital mental health interventions.
- Trial name
- NCT04287296
- Testing
- Wakey!
- Where
- United Kingdom
- Volunteers
- 3,993 people, healthy volunteers welcome
- Sponsor
- Method X Studios Ltd
Mental Health, Quality of Life
Impact of COVID-19 on Mental Health of Health Care Workers
The impact of the current Covid-19 pandemic on healthcare workers is enormous. This longitudinal study investigates the prevalence of mental health problems and the quality of life of healthcare workers during and after the…
- Trial name
- COVID-Impact (NCT04382196)
- Testing
- Online survey
- Where
- Belgium
- Volunteers
- 524 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Work-Related Stress
Stop for Stress - a Randomized Controlled Trial Comparing an Online and a Group-based Format of an Intervention for Work-related Stress
Work-related stress is a major public health concern, causing sickness absenteeism and impaired health and well-being. Many afflicted with severe work-related stress will not receive evidence-based treatment due to geographical…
- Trial name
- NCT06799403
- Testing
- Therapist-assisted online stress management, Group-based face-to-face stress management
- Where
- 2 sites in Denmark
- Volunteers
- 220 people
- Sponsor
- Lea Nørgaard Sørensen
Uncertain Viability of Pregnancy, Anxiety
Psychological Impact of Predicting Early Pregnancy Outcomes in Women With Pregnancy of Uncertain Viability
This study will evaluate if providing women diagnosed with an intrauterine pregnancy of uncertain viability with a percentage likelihood of ongoing viability of their pregnancy at the time of the follow-up ultrasound, will result…
- Conditions
- Uncertain Viability of Pregnancy, Anxiety, Depression
- Trial name
- IMPROVE (NCT03264170)
- Testing
- Prediction of pregnancy outcome
- Volunteers
- 250 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Psychological Distress
Creating Access to Resources and Economic Support
The goal of this study is to test the ability of small grants and/or peer support to improve mental health among transgender people experiencing material hardship. The main questions the study will answer are: 1.
- Trial name
- CARES (NCT05971160)
- Testing
- Financial education videos, Microgrant, Peer mentoring
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy
Impact of Stress and Sleep Management on Emergency Professionals
The investigators hypothesize that a recovery management program could have an impact on emergency nurses and physicians by improving their sleep and reducing their psychological and physiological responses when dealing with…
- Trial name
- REST (NCT05251246)
- Testing
- recovery management program
- Where
- France
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Erectile Dysfunction (ED)
The Feasibility of Using Dornier Machine in Patients With Erectile Dysfunction, a Pilot Study.
Extracorporeal Shockwave Therapy (ESWT) is a well-established modality for treating various urological and musculoskeletal conditions.
- Trial name
- DED-Pilot (NCT07331961)
- Testing
- extracorporeal shock wave therpy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Stress, Psychological, Stress, Emotional
The Effects of Mindfulness-Based Stress Reduction Program for Family or Caregivers of Children With Motor Disabilities
The present study aims to investigate the effect of a mindfulness-based program on perceived stress, severity of anxiety, parents'/caregivers' quality of life and their children, cortisol and IL-6 blood concentrations.
- Conditions
- Stress, Psychological, Stress, Emotional, Stress
- Trial name
- NCT06557486
- Testing
- Mindfulness-Based Stress reduction
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universitat de Lleida
Cognitive Change, Processing, Visual Spatial
Effects of a Complex, Partnered Martial Arts-based Intervention on Cognitive Function
The investigators' study is designed to test whether brief exposure to a martial arts-based intervention (a coordinative, partnered training exercise known as "Hubod"), can improve cognitive function to a greater degree than…
- Conditions
- Cognitive Change, Processing, Visual Spatial, Inhibition (Psychology), Working Memory
- Trial name
- HUBOD (NCT04760054)
- Testing
- HUBOD, Active Comparator, Control Condition
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Interpersonal Functioning, Psychological Distress
Assessing the Mechanism of Change of Functional Analytic Psychotherapy
This study seeks to assess the mechanisms of change of Functional Analytic Psychotherapy (FAP). FAP is a process-outcome psychotherapy that focuses on the therapeutic relationship, providing services to participants presenting…
- Trial name
- FAP (NCT03562962)
- Testing
- Functional Analytic Psychotherapy
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Reno