Clinical trials: Psychiatric Disorders Mood
Major Depressive Disorder
Mobile Screening for Major Depressive Disorder in Adults From an Ethnically and Socioeconomically Diverse Population.
Major depressive disorder (MDD) is a mental disorder leading to a variety of emotional and physical problems affecting almost 300 million people worldwide.
- Trial name
- MOOD (NCT05989412)
- Testing
- Patient health questionnaire-9 via the Your Research application
- Where
- Netherlands
- Volunteers
- 1,786 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Bipolar Disorder, Bipolar Affective Psychosis
Effectiveness of Quetiapine XR on the Control of Symptoms of Manic Phase of Bipolar Disorder.
The primary purpose of the study is to assess the efficacy of Quetiapine extended release 600mg per day either as monotherapy or combined therapy in the treatment of patients with mania associated to Bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar Affective Psychosis, Mania, Manic Disorder
- Trial name
- EMMY (NCT00521365)
- Testing
- Quetiapine 600mg
- Where
- 7 sites in Mexico
- Volunteers
- 88 people
- Sponsor
- AstraZeneca
Bipolar Disorder
Mood Stabilizer-induced Metabolic Abnormalities in Bipolar Disorder
The potential effects of microbiota in bipolar disorder (BD) with microbiota-related dysfunction have not yet been explored clinically, and the integration of microbiota and pharmacometabolomic approaches can provide us the…
- Trial name
- NCT04486092
- Testing
- Valproic Acid
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Bipolar Disorder
AMIloride for the Treatment of Nephrogenic Diabetes Insipidus for Patients With Bipolar Disorder Treated With Lithium
Lithium (Li) is the leading treatment for BD, protecting against both maniac and depressive relapse, and reducing the risk of suicide and mortality.
- Trial name
- AMIND (NCT05044611)
- Testing
- Anhydrous Amiloride Hydrochloride
- Where
- 2 sites in France
- Volunteers
- 148 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Depressive Symptoms, Major Depressive Disorder
Digital Therapeutic for Adolescent Depressive Symptoms in Cardiology and Gastroenterology
The primary aim of this pilot study is to assess the feasibility, acceptability, and preliminary evidence of efficacy of a self-guided, cognitive behavioral therapy (CBT)-based mobile app intervention (SparkRx) for symptoms of…
- Conditions
- Depressive Symptoms, Major Depressive Disorder, Depression, Cardiology
- Trial name
- NCT05461599
- Testing
- SparkRx Mobile App
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Limbix Health, Inc.
Premature, Low Birth Weight
Effect of Kangaroo Baby Massage on Mother-infant Interaction at Home
The objective of this randomized clinical trial will determine the effectiveness of nursing intervention (Kangaroo Baby Massage) on the interaction between mothers and premature, low birth weight infants at home The dyad mother…
- Conditions
- Premature, Low Birth Weight, Mother-Infant Interaction, Gain, Weight
- Trial name
- KBM (NCT04908332)
- Testing
- Kangaroo Baby Massage
- Where
- Colombia
- Volunteers
- 68 people
- Sponsor
- Universidad Nacional de Colombia
Psychomotor Agitation, Schizophrenia
A Study of Staccato Loxapine (ADASUVE®) for Inhalation
Phase 3 safety and efficacy study of Staccato Loxapine in the treatment of acute agitation in schizophrenic or bipolar disorder patients.
- Conditions
- Psychomotor Agitation, Schizophrenia, Bipolar Disorder
- Trial name
- NCT04148963
- Testing
- Inhaled loxapine
- Volunteers
- 150 people
- Sponsor
- Lee's Pharmaceutical Limited
Major Depressive Disorder
A Phase II Study of PDC-1421 Capsule to Evaluate the Safety and Efficacy in Patients With Major Depressive Disorder
The purpose of this study is to evaluate the safety and efficacy in patients with major depressive disorder.
- Trial name
- NCT02395978
- Testing
- PDC-1421 Capsule
- Where
- 5 sites in United States, Taiwan
- Volunteers
- 72 people
- Sponsor
- BioLite, Inc.
Bipolar Disorder
Rostral Dorsal Cingulum Bundle Connectivity in Patients With Bipolar Disorder
The overall goal of this study is to employ diffusion-weighted imaging (DWI) and tractography to investigate differences in connectivity in the rostral dorsal cingulum bundle (CB) in patients with bipolar disorder type I (BDI) or…
- Trial name
- NCT02655978
- Testing
- Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Anxiety Disorders, Depressive Disorders
Short-term, Intensive Psychodynamic Group Therapy Versus Cognitive-behavioral Group Therapy in the Day Treatment
Background: Psychodynamic and cognitive-behavioral group therapies are frequently applied in day hospitals in the treatment of anxiety disorders, and comorbid depressive or personality disorders in Poland.
- Conditions
- Anxiety Disorders, Depressive Disorders, Personality Disorders
- Trial name
- NCT02126787
- Testing
- Intensive Group Analytic Psychotherapy, Intensive transdiagnostic cognitive-behavioral group therapy
- Where
- Poland
- Volunteers
- 123 people
- Sponsor
- Medical University of Warsaw
Depression, Postpartum Depression
Cognitive-Behavioral Therapy (CBT) in Women Discontinuing Antidepressant for Pregnancy
The overarching goal of this study is to adapt a cognitive behavioral prevention of recurrence treatment (CBT-PR) for women with a history of recurrent major depressive disorder who decide to discontinue their maintenance…
- Conditions
- Depression, Postpartum Depression, Antenatal Depression
- Trial name
- NCT01453114
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Schizophrenia and Related Disorders, Major Depressive Disorder
Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure
Schizophrenia, bipolar and major depressive disorders collectively affect over 10 million people across the EU and are associated with annual healthcare and societal costs in excess of 100 billion Euros.
- Conditions
- Schizophrenia and Related Disorders, Major Depressive Disorder, Bipolar Depression
- Trial name
- INTENSIFY (NCT05603104)
- Testing
- Clozapine, Esketamine Nasal Product, Escitalopram
- Where
- Israel
- Volunteers
- 1,254 people
- Sponsor
- Dr. Inge Winter
Dementia, Mood
Bright Light Therapy in Older Adults With Moderate to Very Severe Dementia
INTRODUCTION: Bright light therapy (BLT) has demonstrated positive effects on sleep, mood, and behavioral problems in older adults with dementia. However, there is little research in people with advanced stages of dementia.
- Conditions
- Dementia, Mood, Behavior
- Trial name
- BLT-Dementia (NCT04949984)
- Testing
- Bright light therapy
- Where
- Spain
- Volunteers
- 39 people
- Sponsor
- Universidade da Coruña
Anxiety, Depression
Developing Resilience and Anxiety Management Through the Arts
The Developing Resilience and Anxiety Management Through the Arts (DRAMA) Study examines the degree to which the arts can help to address stress, anxiety, and sad mood in children and adolescents.
- Conditions
- Anxiety, Depression, Mood
- Trial name
- DRAMA (NCT07033052)
- Testing
- Improvisation + Wellness, Improvisation, Social Craft
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Case Western Reserve University
Depressive Disorder, Major
Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major Depression
In essence the researchers are hoping to test two separate hypotheses (described below in the form of research questions). Therefore, the proposed analysis has been outlined according to each hypothesis.
- Trial name
- NCT03207438
- Testing
- Quetiapine 50 MG Extended Release Oral Tablet, Quetiapine Fumarate XR 150-300 mg
- Volunteers
- 1,790 people
- Sponsor
- University of Saskatchewan
Major Depressive Disorder, Borderline Personality Disorder
Triage Survey for Psychiatry Research Eligibility
TRIAGE-Psych is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored psychiatry clinical trials.
- Conditions
- Major Depressive Disorder, Borderline Personality Disorder, Generalized Anxiety Disorder
- Trial name
- TRIAGE-Psych (NCT05800925)
- Testing
- Survey
- Where
- 6 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Adams Clinical
Major Depression, Vitamin D Deficiency
Effects of Vitamin D Supplementation on Depression and Inflammatory Markers
The current study is designed as a prospective partially randomized patient preference (PRPP) trial and recruit psychiatric outpatients or inpatients.
- Trial name
- NCT04898725
- Testing
- Vitamin D3
- Where
- Taiwan
- Volunteers
- 142 people
- Sponsor
- Mackay Memorial Hospital
Mood, Depression Disorders
Technology Exposure and Child Health: Wellness Impact and Social Effects: An Observational Product Registry Study
The goal of this study is to understand how children's mobile device usage (smartphones or tablets), including social media use and online games, are related to their mental wellness and mental health, as well as some aspects of…
- Conditions
- Mood, Depression Disorders, Anxiety Disorders, Sleep
- Trial name
- TECHWISE (NCT06664944)
- Where
- United States
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- Aura
Postpartum Depression, Breastfeeding
Midwife-Led Digital Follow-Up After Cesarean Section
This randomized controlled trial aims to evaluate the effect of a midwife-led digital follow-up program on postpartum depression, perceived social support, and breastfeeding self-efficacy in women who will undergo cesarean…
- Conditions
- Postpartum Depression, Breastfeeding, Postpartum Period
- Trial name
- MID-CS (NCT07523932)
- Testing
- Midwife-Led Digital Follow-Up Program
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Inonu University
Unipolar Depression, Bipolar Depression
Investigating tDCS as a Treatment for Unipolar and Bipolar Depression
Transcranial direct current stimulation (tDCS) is a novel treatment approach for depression that has shown promising efficacy in four recent double-blind, randomized, sham-controlled trials (RCT) and a meta-analysis.
- Trial name
- NCT01562184
- Testing
- Soterix tDCS device
- Where
- 6 sites in United States, Australia
- Volunteers
- 120 people
- Sponsor
- The University of New South Wales