Clinical trials: Protein Intolerance
Non-celiac Wheat Sensitivity
Lactose Intolerance and Cow's Milk Protein Allergy in Non-celiac Wheat Sensitivity Patients
In the last few years a new clinical entity has emerged which includes patients who consider themselves to be suffering from problems caused by wheat and/or gluten ingestion, even though they do not have celiac disease (CD) or…
- Trial name
- NCT03008252
- Testing
- Lactose breath test, DBPC cow's milk protein challenge
- Where
- 2 sites in Italy
- Volunteers
- 300 people
- Sponsor
- University of Palermo
Protein Intolerance
A2 GUM Post-Market Effectiveness Study
This is a post-market, real-life effectiveness study of A2 growing up milk on toddlers' gut comfort.
- Trial name
- NCT03698058
- Testing
- Toddler milk
- Where
- China
- Volunteers
- 387 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Milk Intolerance, Milk Hypersensitivity
Goat vs. Cow Milk Digestive Tolerance
The objective of this study is to assess to what extent goat's milk is better tolerated than cow's milk among individuals who report being intolerant to cow's milk, and, if so, to understand the underlying factors.
- Conditions
- Milk Intolerance, Milk Hypersensitivity, Cow Milk Protein Sensitivity
- Trial name
- DIGIGOAT (NCT07239856)
- Testing
- Cow milk, Goat Milk
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
Enteral Nutrition, Feeding Intolerance
Evaluation of Status of Early Reached Target Enteral Nutrition and IFABP as Biomarker of Feeding Intolerance in Critically Ill Children
Stage 1 - Evaluation of Status of Early Reached Target Enteral Nutrition in critically ill children in the PICU (ERTEN in PICU).
- Conditions
- Enteral Nutrition, Feeding Intolerance, Intestinal Fatty Acid Binding Protein
- Trial name
- ERTENIFABPICU (NCT02598375)
- Testing
- Feeding intolerance
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Gazi University
Individual Difference, Food Sensitivity
Investigating the Influence of Age and Saliva Flow on the Perception of Protein Fortified Foods and Beverages
Brief Summary: This study aims to investigate whether protein fortification of foods and beverages causes mouthdrying and mucoadhesion and whether this is influenced by age and saliva flow.
- Conditions
- Individual Difference, Food Sensitivity, Food Preferences
- Trial name
- NCT04302779
- Testing
- Solid Model, Liquid Model
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Reading
Food Intolerance
Athlete Whey Protein Sensitivity: Prevalence and Performance
The objective of this study is to identify the prevalence of whey protein sensitivity in UIW athletes and to assess the effectiveness of 4-weeks of whey versus plant-based protein supplementation on athletic performance and…
- Trial name
- NCT05482997
- Testing
- Whey Protein Concentrate, Pea Protein Isolate, Rice Protein Concentrate, Hemp Protein
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of the Incarnate Word
Lactose Intolerance
Effects Comparison of A1 and A2 Milk on Gastrointestinal Physiology, Symptoms and Cognitive Behavior
This is a single-site, double-blinded, randomized, controlled, 2X2 cross-over study aiming to compare effects of milk containing only A2 type beta casein versus milk containing both A1 and A2 beta casein proteins on the…
- Trial name
- NCT02406469
- Testing
- Oral consumption milk Tetra Pak
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- a2 Milk Company Ltd.
Insulin Resistance, Impaired Glucose Tolerance
Using a Complex Carbohydrate Mixture to Steer Fermentation and Improve Metabolism in Adults With Overweight and Prediabetes (DISTAL)
The purpose of this study is to investigate the effects of a fibre mixture added to a high-protein diet on metabolic, gut and brain health.
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, PreDiabetes, Overweight and Obesity
- Trial name
- DISTAL (NCT05354245)
- Testing
- Fibre supplement (potato-pectin), High-protein diet
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Familial Mediterranean Fever, Heat Intolerance
Heat Intolerance in the Group of FMF Patients
There now causation between Heat Intolerance and FMF that were showed in studies till now. We suggest that the prevalence of Heat Intolerance in the group of the FMF patients will be significantly higher than in the group of…
- Conditions
- Familial Mediterranean Fever, Heat Intolerance, Heat Tolerance Test
- Trial name
- NCT01059279
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Sheba Medical Center
Pre Diabetes, Obesity
Balanced (Egg) Protein During Obesity Reduction: Differential Responses of Insulin Resistance by Race
The purpose of the trial is to assess the effects of combining regular, generous intakes of high quality protein (with substantial amounts provided from whole eggs and egg whites) with calorie restriction on insulin resistance…
- Trial name
- EGGSPDITe (NCT03771261)
- Testing
- Weight Loss, Egg Protein
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Duke University
Colic, Nephropathy
Neonatal Outcome of Children With Antenatal Colic Hyperechogenicity
Fetal colic hyper-echogenicity is a presenting symptoms for cystinuria lysinuria. A few cases of fetuses with dibasic protein intolerance (more complex prognosis) presented with colic hyper-echogenicity antenatal.
- Trial name
- COLONECHOGENE (NCT04983069)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Montpellier
Feeding Intolerance
Tolerance of an Extensively Hydrolyzed Protein Infant Formula Versus a Premature Infant Formula
To evaluate the use of a hypoallergenic infant formula containing an extensively hydrolyzed protein source for routine nutrition.
- Trial name
- NCT01987154
- Testing
- Marketed cow milk-based premature infant formula, Marketed extensively hydrolyzed casein infant formula
- Where
- Italy
- Volunteers
- 61 people
- Sponsor
- Mead Johnson Nutrition
Arterial Stiffness, Dietary Modification
Egg Protein Hydrolysate and Vascular Function
The incidence of type 2 diabetes mellitus (T2DM) is rapidly growing. Patients with T2DM are at increased risk of developing long term micro- and macrovascular complications.
- Conditions
- Arterial Stiffness, Dietary Modification, Impaired Glucose Tolerance, Type 2 Diabetes Mellitus
- Trial name
- NCT01559896
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Pre Diabetes
Role of Glycaemic Index and High Protein Meal in Response of Blood Biomarkers for Pre-diabetes
This study aims to demonstrate the effectiveness of increased protein ingestion, particularly when coupled with a low glycaemic index (GI) to reduce biomarkers related to high risk of diabetes.
- Trial name
- NCT03309254
- Testing
- High Glycemic Index, Low Glycemic Index
- Where
- Singapore
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Metabolism, Trauma
ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with…
- Conditions
- Metabolism, Trauma, Nutritional Deficiency, Protein Malnutrition
- Trial name
- ACCUMULATE (NCT05647135)
- Testing
- Medical food
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Absorption; Disorder, Protein, Protein Malabsorption
Genepro Generation 3 Protein Bioavailability Compared to Whey Protein
Objective of Clinical Trial: To test, in a blinded study the bioavailability of Genepro Generation 3 (GEN3) Protein as compared to whey protein.
- Conditions
- Absorption; Disorder, Protein, Protein Malabsorption, Protein Intolerance
- Trial name
- Gen3 (NCT04615858)
- Testing
- Genepro Generation 3 Protein, Whey Protein
- Where
- 2 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Musclegen Research, Inc.
Pre-diabetes
High Protein Diet on Transcriptomic, Metabolomics, Hepatic and Pancreatic Fat Anatomy and Physiology in Asian Indians With Pre-diabetes
Diabetes/ prediabetes is a substantial problem in India not only because it itself can be associated with morbidities such as coronary artery disease but also because it is a point of importance for the prevention of other…
- Trial name
- NCT05925933
- Testing
- Intervention
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Diabetes Foundation, India
Pre-diabetes
Impact of High Fiber and Vegetal Protein Diet on Gut Health and Immunity Biomarkers in Prediabetic Patients
The research area that focuses on the links between nutrition and health, nutrition and the immune system as well as nutrition-related public health interventions, which often falls into the gap between the agricultural and…
- Trial name
- PreVegDiet (NCT06147323)
- Testing
- Normal Healthy Diet, Seaweed Group
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Roehampton
Glucose Intolerance
C-reactive Protein and Endothelial Dysfunction in Women With Glucose Intolerance
The goal of this study is to determine whether markers of vascular inflammation (such as c-reactive protein) can predict endothelial dysfunction (as measured by flow-mediated dilation) in postmenopausal women with glucose…
- Trial name
- NCT00589355
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Yale University
Sarcopenic Obesity, Bariatric Surgery Candidate
Effect of Protein Supplementation and a Structured Exercise Program on Muscle in Women After Bariatric Surgery.
Obesity is considered a chronic disease that increases the risk of developing diseases that reduce life expectancy. The treatment of obesity is complex.
- Conditions
- Sarcopenic Obesity, Bariatric Surgery Candidate, Nutritional Deficiency, Protein Intolerance
- Trial name
- SarcoFit (NCT04771377)
- Testing
- Protein Supplementation
- Where
- Spain
- Volunteers
- 75 people
- Sponsor
- Hospital Clinic of Barcelona