Clinical trials: Prosthesis and Implants
Failure of Dental Prosthesis
Comparison of Two Implant Prosthetic Pathways
To assess and compare the esthetic outcome and clinical performance of anterior maxillary all ceramic implant single crowns based either on prefabricated zirconia abutment veneered with pressed ceramics or on a CAD/CAM…
- Trial name
- NCT02905838
- Testing
- Anatomic e.max Abutment, CAD/CAM CARES Abutment
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Bern
Prostheses and Implants
IceExplore TF Liner Alpha Investigation
Single group prospective repeated measures comparing breathable liner and breathable socket to conventional enclosed silicone liner and socket system.
- Trial name
- NCT04787484
- Testing
- IceExplore TF breathable liner and Direct Socket drilled with holes
- Volunteers
- 18 people
- Sponsor
- Össur Iceland ehf
Rheumatoid Arthritis, Systemic Lupus Erythematosus
Ascension® Post- Approval Study; PyroCarbon Metacarpophalangeal Total Joint Prosthesis
This study is a non-randomized, consecutive enrollment, one-year post-approval study of patients who are treated with the Ascension® MCP.
- Conditions
- Rheumatoid Arthritis, Systemic Lupus Erythematosus, Osteoarthritis, Post-traumatic Arthritis
- Trial name
- MCP (NCT02408471)
- Testing
- Ascension® MCP Finger Implant
- Where
- 9 sites in United States
- Volunteers
- 97 people
- Sponsor
- Smith & Nephew, Inc.
Prostheses and Implants
Advanced Prosthetic Devices for Lower Limb Amputees
Lower limb amputation is an emerging global health concern. Currently, there are over 1.6 million amputees in the U.S. and around 6000 new amputations are recorded per annum in the UK.
- Trial name
- NCT04197011
- Testing
- prosthetic device
- Where
- United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Nottingham Trent University
Partial Edentulism Class II, Dental Implants
Porcelain-fused-to-metal Versus Zirconia Implant- Supported in Mandibular Kennedy Class II
The goal of this randomized clinical trial is to compare biting force and patient satisfaction in three groups. Patients in the control group number one will receive a CoCr removable partial denture, and in the other two groups…
- Conditions
- Partial Edentulism Class II, Dental Implants, Implant
- Trial name
- NCT06150768
- Testing
- Cobalt Chromium Removable Partial Denture, Implant-Supported Porcelain-Fused-to-Metal-Fixed Partial Denture, Implant-Supported Zirconia Fixed Partial Denture.
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Aging of Breast Implants
Understanding the Phenomena of Aging and Rupture of Breast Implants
Breast implants, like all implantable medical devices, are subject to wear and tear as they age in the body. In addition to this wear and tear, they are subject to external trauma, whether accidental during daily life, during…
- Trial name
- CRIMA (NCT05527132)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Peri-Implant Diseases
Salivary Biomarkers in Different Implant-Supported Prostheses
This observational cross-sectional study compared salivary biomarkers among adults with different types of implant-supported prosthetic rehabilitation and periodontally healthy adults with natural teeth.
- Trial name
- NCT07813845
- Where
- Turkey (Türkiye)
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Prosthesis and Implants
Transdermal Compress IDE Study
The purpose of this study is to evaluate the safety and effectiveness of the Transdermal Compress device in participants with Transfemoral Amputations.
- Trial name
- NCT06134167
- Testing
- Transdermal Compress Device
- Where
- 9 sites in United States
- Volunteers
- 100 people
- Sponsor
- Balmoral Medical company
Complications; Breast Prosthesis, Infection or Inflammation
Antibiotics and Tissue Expanders in Breast Reconstruction
This study is a randomized controlled non-blinded double arm study examining the effect of routine postoperative oral antibiotic therapy in preventing postoperative surgical site infections after breast reconstruction.
- Trial name
- NCT01899690
- Testing
- antibiotic
- Sponsor
- Emory University
Jaw, Edentulous, Poor Bone Quality
Treatment With Fixture Microthread™ in Patients With Poor Bone Quality and no Teeth in the Upper Jaw, When Using Two-Stage Surgery
The primary objective of the study is to evaluate the long-term survival rate of individual implants and prostheses when treating edentulous upper jaws of poor bone quality with Fixture MicroThread™ (Micro-Macro).
- Trial name
- NCT00748670
- Testing
- Fixture MicroThread (Micro-Macro)
- Where
- 3 sites in United States, Sweden
- Volunteers
- 23 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Knee Arthritis, Knee Osteoarthritis
In-vivo Wear Behaviour of AS Coated Versus Uncoated Columbus® Total Knee Prosthesis
This clinical study is a Post-Market Clinical Follow-Up (PMCF) measure and is aiming to compare the in-vivo wear behaviour of the Columbus® total knee prosthesis between the standard Cobalt Chromium (CoCr) and the multilayer…
- Conditions
- Knee Arthritis, Knee Osteoarthritis, Primary Osteoarthritis of Knee Nos, Secondary Osteoarthritis of Knee Nos
- Trial name
- COLRAS (NCT05509972)
- Testing
- total knee prosthesis implantation
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Aesculap AG
Jaw, Edentulous, Partially
Effect of the Abutment-Prosthesis Connection on Marginal Bone Loss and Gingival Sealing Around Dental Implants
In dental implant restoration, available literature demonstrates the advantage of using tall abutments, with a change of diameter with respect to the implant and a conical internal connection in the abutment-implant gap.
- Trial name
- NCT05883202
- Testing
- Connect®, Multi-unit
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Implant Infection
Maintenance Protocol for Implant Supported Hybrid Prosthesis.
The study we intend to carry out aims to analyze the clinical and microbiological effects of a new maintenance protocol for implant-supported hybrid prostheses.
- Trial name
- NCT05482490
- Testing
- Maintenance protocol for the hygiene of implant supported prosthesis
- Where
- Italy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Cagliari
Edentulous Jaws
Computer Assisted Implant Surgery and Immediate Loading
Purpose: The aim of this study was to analyze the clinical and radiographic outcomes of 23 edentulous jaws treated with 3D software planning, guided surgery, immediate loading and restored with Cad-Cam Zirconia and titanium full…
- Trial name
- NCT01866696
- Testing
- oral implants
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Università degli Studi di Sassari
Gas Incontinence, Soilings, Fecal
Gatekeeper for Soiling and Gas Incontinence
Faecal incontinence has a broad spectrum of symptoms. Some patients only suffer commonly considered mild symptoms: gas incontinence and soiling, but patients' quality of life is significantly impaired.
- Trial name
- NCT05222217
- Testing
- Gatekeeper
- Volunteers
- 13 people
- Sponsor
- Hospital Mutua de Terrassa
Hip Arthritis
Post Market, Retrospective Study to Evaluate Patients Implanted With Medacta Versafit Cup DM ™️ 2 Years Post-op
This is a post-market, retrospective with one prospective visit, multi- center study, designed to assess the clinical outcomes, surgical details including Anterior or Posterior surgical approach, and collect all complication data…
- Trial name
- NCT03897387
- Where
- 3 sites in United States
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Diabetes Mellitus, Dental Implants
Apico-coronal Position of the Implant in Edentulous Diabetics With Implant-retained Overdentures
Diabetes Mellitus (DM) is a recognized factor affecting implant complication rates, including peri-implantitis and peri-implant bone loss, and the apico-coronal position of implants seems interfere on the conditions of…
- Trial name
- NCT03988140
- Testing
- Dental Implant Placement and subsequent prosthetic reabilithation
- Volunteers
- 22 people
- Sponsor
- Paulista University
Stenosis of Vascular Prosthetic Devices, Implants and Grafts
Post-Approval Study for the FLAIR Endovascular Stent Graft
The purpose of this study is to confirm the long-term safety and effectiveness of the FLAIR Endovascular Stent Graft for treatment of stenoses at the venous anastomosis of ePTFE or other synthetic arteriovenous (AV) access grafts.
- Trial name
- RENOVA (NCT00677235)
- Testing
- FLAIR Endovascular Stent Graft, PTA
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- C. R. Bard
Missing Teeth
A Full-Arch Implant- Supported Prosthesis in the Upper and/or Lower Jaw-USA
This study follows subjects who have agreed with their dentist that their failing teeth or missing teeth all need replacing. This study follows their standard routine care with some additional assessments.
- Trial name
- NCT03655990
- Testing
- Treatment with the JUVORA™ Dental Disc
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Juvora Ltd.
Surgical Wound Infection
Local Gentamicin Application to Reduce Postoperative Infection Rate
The majority of elderly patients with a displaced fracture of the proximal femur are now treated with a hemiarthroplasty. Prosthetic joint infection is a devastating complication, and the infection rate is high in this group of…
- Trial name
- NCT01287780
- Testing
- Collagen-gentamicin sponge
- Where
- 5 sites in Norway
- Volunteers
- 800 people
- Sponsor
- Oslo University Hospital