Clinical trials: Prosthesis
Aortic Valve Stenosis, Implantation, Heart Valve Prosthesis
Supra-Annular vs. Annular ValvEs for Small Annuli
Open-label, prospective randomized comparison of Supra-annular valves (Medtronic Evolut Pro) vs. annular valves (Edwards Sapien Ultra) for small annuli (≤23 mm)
- Trial name
- SAVE (NCT04372381)
- Testing
- Transcatheter aortic valve replacement (Edwards Sapien Ultra or Medtronic Evolut Pro
- Where
- 3 sites in United States
- Sponsor
- University of Arizona
Transfemoral Amputation, Limb Loss
Effect of a Microprocessor-controlled Prosthetic Knee Joint on K2 Level Ambulators
Microprocessor-controlled knees (MPKs) automatically adjust resistance or damping in the joint to improve swing- and/or stance-phase control as appropriate for the prosthesis user during gait.
- Conditions
- Transfemoral Amputation, Limb Loss, Limb Absence
- Trial name
- MPK-K2 (NCT07103798)
- Testing
- College Park ICON, Conventional NMPK
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Breast Cancer
Quality of Life in Patients With Standard External Compared to Custom-made Breast Prosthesis.
Despite improvements in surgical techniques, approximately 30% of mastectomies are still performed. Definitively or temporarily, one of the alternatives to restore a volume in the bra is the external breast prosthesis.
- Trial name
- MEAVANTI (NCT03981263)
- Testing
- MEAVANTI prothesis, Standard prothesis
- Where
- France
- Volunteers
- 64 people
- Sponsor
- University Hospital, Toulouse
Knee Prosthesis
Study of Patients With Knee Prostheses Treated With Noninvasive Neuromodulation
It will consist of a randomized clinical trial with a control group. The sample will be distributed as homogeneously as possible into two groups, which will be randomly divided into a control group, to which the usual general…
- Trial name
- NCT06134999
- Testing
- Non-invasive Neuromodulation
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- University of Las Palmas de Gran Canaria
Dental Prosthesis Failure
Application of 3D Printed Removable Denture Prosthesis Framework for Partial Edentulous Patients
Tooth loss is a major dental problem worldwide. A recent study in Singapore found that approximately one third of adults aged over 65 are living without any natural teeth.
- Trial name
- NCT04304222
- Testing
- 3D Printed Denture Framework
- Where
- Singapore
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Heart Valve Diseases, Heart; Complications, Valve, Prosthesis
Prevention of Renal Failure by Nitric Oxide in Prolonged Cardiopulmonary Bypass.
Prolonged periods of cardiopulmonary bypass (CPB) cause high levels of plasma free haemoglobin(Hb) and are associated with increased morbidity.
- Conditions
- Heart Valve Diseases, Heart; Complications, Valve, Prosthesis, Cardiac Valve Replacement Complication
- Trial name
- NCT01802619
- Testing
- inhaled nitric oxide, inhaled Nitrogen
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Xijing Hospital
Amputation, Prosthesis User
Sonomyographic Upper Limb Prosthetics: A New Paradigm
The vast majority of all trauma-related amputations in the United States involve the upper limbs. Approximately half of those individuals who receive a upper extremity myoelectric prosthesis eventually abandon use of the system…
- Trial name
- NCT05376332
- Testing
- Sonomyographic Prosthesis, Myoelectric direct control prosthesis, Myoelectric pattern recognition prosthesis
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- George Mason University
Amputation
Does Walking Performance Improve When Veterans With Leg Amputations Are Given Visual Feedback?
Previous studies suggest that Veterans with below the knee amputation using passive-elastic or powered prostheses have impaired physical function, which could increase the risk of osteoarthritis, leg/back pain, and…
- Trial name
- NCT03974945
- Testing
- Passive-elastic prosthetic foot, Powered ankle-foot prosthesis
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Peri-implant Mucositis, Peri-Implantitis
Peri-implant Disease and Prosthetic Cement: Cross-sectional Study
The main objective of the present clinical study project, of a cross-sectional observational nature, is to evaluate the presence of submucosal cement residues through endoscopic visualization in clinical situations with…
- Trial name
- NCT05945836
- Where
- Italy
- Volunteers
- 46 people
- Sponsor
- University of Bologna
Accuracy of Artificial Intelligence in Fixed Dental Prosthesis Design
Artificial Intelligence Versus Conventional Digital Design for Fixed Dental Prosthesis
This in vitro study aims to evaluate the accuracy of an Artificial Intelligence (AI)-based automatic design system for fixed dental prosthesis (FDP) compared with conventional computer-aided design (CAD) software.
- Trial name
- NCT07432165
- Testing
- Conventional CAD-Based Fixed Dental Prosthesis Design, Artificial Intelligence-Based Fixed Dental Prosthesis Design
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- October University for Modern Sciences and Arts
Occlusal Trauma
Effect Of Occlusal Materials Used For All On Four Mandibular Implant Prosthesis With PEEK Framework
This study was performed to compare between the effects of different occlusal materials used for all on four implant supported mandibular fixed prosthesis with PEEK framework.
- Trial name
- NCT06159530
- Testing
- dental implants, peek framework, visio-lign nano composite
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Dental Prosthesis Failure
Clinical Performance of All-ceramic Posterior Crowns. A Randomized, Prospective Clinical.
This is a randomized, prospective clinical trial. The aim of the project is to assess the clinical performance of three types of tooth-supported crowns; monolithic high translucent colored zirconia, crowns of high-translucent…
- Trial name
- NCT04272112
- Testing
- IPS e.max CAD, Ivoclar Vivadent, BruxZir, Glidewell, BruxZir*, Glidewell
- Where
- Sweden
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Malmö University
Prosthesis-Related Infections
Dosing of Antibiotics During Reimplantation of Infected Knee and Hip Prostheses
The purpose of the study is to evaluate the concentrations of antibiotics used as empirical treatment in serum and periprosthetic tissues during reimplantation of infected hip and knee prostheses
- Trial name
- DOSOS (NCT02860767)
- Where
- 5 sites in France
- Volunteers
- 30 people
- Sponsor
- Tourcoing Hospital
Hyperhidrosis
Study to Assess the Efficacy of Botulinum Toxin B (Myobloc) for the Treatment of Prosthesis-associated Sweating
The objective of this study is to determine if Myobloc significantly decreases prosthesis-associated symptomatic sweating in amputees when compared to a saline solution placebo.
- Trial name
- NCT01671800
- Testing
- Botulinum Type B
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Arthroplasty, Replacement, Knee
Evaluation of Triathlon - A New Total Knee Prosthesis System - RSA Triathlon Cruciate Retaining - Cemented vs. Uncemented
The objective is to investigate the Clinical, Radiographic, Roentgen Stereophotogrammetric behaviour and patient outcome when using the Triathlon total knee prosthesis in a prospective randomized clinical trial.
- Trial name
- TriathlonRSA (NCT02525601)
- Testing
- Triathlon CR cemented, Triathlon CR uncemented
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Region Skane
Vestibular Disorder, Bilateral Vestibulopathy
Electrical Stimulation of the Peripheral Vestibular System in Order to Develop a Vestibular Implant
This study has three main goals (1) to explore the effects of electrical stimulations of the peripheral vestibular system(2) to assess the potential of this technique to rehabilitate basic vestibular functions in patients with…
- Conditions
- Vestibular Disorder, Bilateral Vestibulopathy, Bilateral Vestibular Loss
- Trial name
- NCT05246553
- Testing
- Electrical stimulation of the vestibular system, Electrical stimulation of the auditory system, Bilateral vestibulopathy Patients (BV)
- Where
- Switzerland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Nils Guinand
Osteoarthritis, Knee, Osteoarthrosis of Knee
Univation XM France
The study is set up due to regulatory purposes and to collect routine clinical data of the mobile-bearing implant univation XM. The study is designed as a prospective follow-up study with a historic patient cohort who have been…
- Conditions
- Osteoarthritis, Knee, Osteoarthrosis of Knee, Arthritis Knee, Unicompartmental Knee Arthroplasty
- Trial name
- NCT04199481
- Where
- France
- Sponsor
- Aesculap AG
Osteoarthritis, Knee
Investigational Testing of Bodycad Unicompartmental Knee Prosthesis (UKS)
This study is designed to observe clinical outcomes of patient-specific knee arthroplasty in patients with osteoarthritis of the medial condyle.
- Trial name
- NCT03432481
- Testing
- Unicompartmental Knee Arthroplasty Surgery, Bodycad Unicompartmental Knee System (BUKS)
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Laboratoires Bodycad Inc.
Lower Limb Amputation
Overall Functional Evaluation After Amputation of the Lower Limb; Locomotion, Energy Efficiency and Strategies to Adapt to the Prosthesis
It appears necessary to confront the reality of the contribution of technological progress in the creation of prostheses with the specific features of lower limb amputees.
- Trial name
- PROTEOR (NCT03260530)
- Testing
- Locomotor evaluation, Questionnaires
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Nipple-sparing Mastectomy, Immediate Prosthesis Reconstruction
Endoscopic and Robotic NSM with Immediate Prosthesis Breast Reconstruction
Breast cancer is the most common malignant tumor in women. Surgical treatment is the most important treatment for early breast cancer. Breast cancer resection is considered to be a destructive operation.
- Conditions
- Nipple-sparing Mastectomy, Immediate Prosthesis Reconstruction, Endoscopic Surgery, Robotic Surgery
- Trial name
- EnRoNSM (NCT06748677)
- Where
- China
- Volunteers
- 484 people
- Sponsor
- Peking University People's Hospital