Clinical trials: Prostatectomy
Positive Pressure Ventilation
Flow- Versus Volume-controlled Ventilation During Robot-assisted Laparoscopic Radical Prostatectomy
During robot-assisted laparoscopic radical prostatectomy (RALRP), patients are placed under general anesthesia and supported with mechanical ventilation.
- Trial name
- NCT07453810
- Testing
- Flow-Controlled Ventilation, Volume-Controlled Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Prostate Cancer, Robot-Assisted Laparoscopic Radical Prostatectomy
Predicting Operational Difficulties and Outcomes of RARP Based on Preoperative Assessment - Introducing the PIODO Questionnaire
The goal of this observational study is to learn about the factors that affect the course of robot-assisted radical prostatectomy and have an impact on functional and oncological outcomes in patients undergoing RARP.
- Trial name
- NCT06985004
- Testing
- PIODO Questionnaire
- Where
- Poland
- Volunteers
- 288 people
- Sponsor
- Pomeranian Medical University Szczecin
Prostate Cancer
Pneumatic Compression and Post-induction Hypotension
The purpose of this study is to evaluate the effect of pneumatic compression on post-induction hypotension in elderly patients undergoing robot assisted laparoscopic prostatectomy.
- Trial name
- NCT05343689
- Testing
- Pneumatic compression
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Asan Medical Center
Male Stress Urinary Incontinence
Surgery for Male Stress Urinary Incontinence
The purpose of this observational prospective study is to evaluate the success rate (cure plus improvement) of procedures for treatment of male stress urinary incontinence (artificial urinary sphincter or male slings) at 5 years…
- Trial name
- SMUI (NCT05771168)
- Testing
- Artificial urinary sphincter, Male sling
- Where
- Italy
- Volunteers
- 138 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Prostate Cancer
Feasibility of Timesaving When Using Histolog Confocal Laser Endomicroscopy for Margin Assessment in Prostatectomy Specimen
This study investigates a new, faster way to find cancer cells on the surface of the prostate during radical prostatectomy surgery.
- Trial name
- IMARHGIN (NCT07141121)
- Testing
- Histolog Scan
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Prostatic Neoplasms, Quality of Life
Quality of Life in Men Undergoing Robotic Assisted Laparoscopic Radical Prostatectomy Versus Radical Retropubic Prostatectomy
This study is prospective evaluation of quality of life in men undergoing robotic assisted laparoscopic radical prostatectomy versus radical retropubic prostatectomy.
- Trial name
- NCT01173952
- Volunteers
- 350 people
- Sponsor
- Samsung Medical Center
Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI)
The Effect of Mobile-Based Perioperative Education on Urinary Incontinence and Erectile Function After Radical Prostatectomy
This prospective randomized controlled study aims to evaluate the effect of mobile-based perioperative education on postoperative urinary incontinence and erectile function in patients undergoing radical prostatectomy.
- Conditions
- Prostate Cancer (Post Prostatectomy), Urinary Incontinence (UI), Erectile Dysfunction Following Radical Prostatectomy
- Trial name
- MPE-RP (NCT07520916)
- Testing
- Mobile-Based Perioperative Education Program, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Giresun University
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
Low Intensity Shockwave Therapy for Erectile Dysfunction
Low-intensity shockwave therapy (LiSWT) has been deemed "a safe and well-tolerated procedure but its efficacy for the treatment of ED is doubtful and deserves more investigation" by the European Society of Sexual Medicine.
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy, Erectile Dysfunction Following Radiation Therapy, Erectile Dysfunction Due to General Medical Condition
- Trial name
- NCT04434352
- Testing
- Storz Duolith Low-Intensity Shockwave Therapy
- Where
- United States
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Post Prostatectomy Incontinence
Veil Preserving HoLEP vs. Stanadard HoLEP
Postoperative transient stress urine leakage following Holmium laser enucleation of the prostate is one of the problems that frustrate both surgeon and patients Standard HoLEP might be associated with some stretch of the…
- Trial name
- MansprostIV (NCT03494049)
- Testing
- Veil sparring HoLEP, Standard HoLEP
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Mansoura University
Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus
A Tissue Sparing, Laser Assisted Penile Prosthesis Implantation Technique
A surgical technique using laser assisted penile prosthesis implantation
- Conditions
- Erectile Dysfunction, Erectile Dysfunction Associated With Type 2 Diabetes Mellitus, Erectile Dysfunction Due to Arterial Disease, Erectile Dysfunction Due to Arterial Insufficiency
- Trial name
- TSLA (NCT06743048)
- Testing
- Tissue Sparing Laser Implantation
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Cairo University
Lower Urinary Tract Symptoms
Effect of Radical Prostatectomy on Involuntary Pelvic Floor Muscle Contraction
This study evaluate the effect of radical prostatectomy on involuntary pelvic floor muscle contraction
- Trial name
- NCT03574298
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Pierre and Marie Curie University
Prostate Cancer
PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer
Background: The immune system is the cells and organs in the body that recognize and fight infection and cancer. The prostate specific antigen (PSA)/TRICOM (PROSTVAC) vaccine might teach the immune system to find and kill certain…
- Trial name
- NCT02933255
- Testing
- PROSTVAC-V/F, Nivolumab, Prostatectomy
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- National Cancer Institute (NCI)
Biochemical Failure
Effects of Brassica or Indole-3-carbinol on Prostatectomy Patients With PSA Recurrence
Pilot and feasibility diet and phyto-agent intervention among healthy men at risk for prostate cancer progression.
- Trial name
- NCT00579332
- Testing
- brassica intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Vanderbilt University
Prostate Cancer Surgery, Ambulatory Care
Prospective Comparative Study Evaluating the Early Complications of Robot-assisted Radical Prostatectomy Performed as an Outpatient Versus an Inpatient Procedure.
The goal of this clinical trial is to demonstrate that outpatient management for robotic-assisted radical prostatectomy is not inferior to inpatient management in terms of the occurrence of early post-operative complications.
- Conditions
- Prostate Cancer Surgery, Ambulatory Care, Outpatient Surgery
- Trial name
- PROSTAMBU (NCT06822452)
- Testing
- radical prostatectomy
- Where
- 12 sites in France
- Volunteers
- 510 people
- Sponsor
- Elsan
Prostate Cancer
Evaluating Return to Continence and Potency Following Radical Prostatectomy
The purpose of this research is to determine if using human placental membrane (also called an allograft) helps to improve recovery time for erectile function and bladder control after having robot-assisted radical prostatectomy…
- Trial name
- NCT05742334
- Testing
- Robot-Assisted Radical Prostatectomy with MLG-COMPLETE Allograft Implantation, MLG-COMPLETE Allograft Implantation
- Sponsor
- Wake Forest University Health Sciences
Prostate Cancer, Neuromuscular Blockade
Recovery From dNMB Using Different Sugammadex Doses in Elderly Patients Undergoing Robot-assisted Prostatectomy
The aim of this prospecive randomized study is to evaluate the effects of a dose of sugammadex increased by 50% compared to a standard dose on recovery time from deep neuromuscular block in elderly patients undergoing…
- Trial name
- RECIR (NCT04854993)
- Testing
- Sugammadex 6 mg/kg, Sugammadex 4 mg/kg
- Where
- Italy
- Volunteers
- 34 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain
Effects of Perioperative B&O Suppositories on Post-op Pain and Morphine Use After Laparoscopic Prostatectomy
This study is evaluating the effect of a Belladonna and Opium suppository administered intraoperatively on post operative pain after laparoscopic radical prostatectomy for prostate cancer. This is a blinded randomized study.
- Trial name
- NCT00863928
- Testing
- belladonna 16.2 mg and opium 60 mg suppository
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Benaroya Research Institute
Prostate Cancer
Radical Prostatectomy Without Prostate Biopsy Following PSMA PET/CT Based on Diagnostic Model
The goal of this prospective, single-center, single-arm trial is to evaluate the positive predictive values between 18F-PSMA-1007 PET/CT based on diagnostic model in patients with suspicious of prostate cancer.
- Trial name
- RPWPB (NCT05587192)
- Testing
- 18F-PSMA-1007 PET/CT based on diagnostic model
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Anhui Provincial Hospital
Prostatic Adenocarcinoma
Prediction of the Risk of Biochemical Relapse After Radical Prostatectomy for Prostate Cancer Using Radomics on Pre-therapeutic MRI
With 50% of post-operative biochemical failure, efficient predictive models are needed to guide post-operative management. Radiomic features are quantitative features extracted from medical imaging, supposed to be correlated with…
- Trial name
- PREBOP (NCT04063800)
- Where
- 2 sites in France
- Volunteers
- 195 people
- Sponsor
- University Hospital, Brest
Erectile Dysfunction, Erectile Dysfunction Following Radical Prostatectomy
MENDiP: Measurements of Overnight Penile Temperature to Evaluate Nocturnal Erection Detection in Patients With Absence of Erectile Functioning After Robot-assisted Radical Prostatectomy
Nocturnal erection detection with the outdated RigiScan is the golden standard for erectile dysfunction (ED) nature differentiation.
- Trial name
- MENDiP (NCT05578157)
- Testing
- Feeling Hot sensor
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- St. Antonius Hospital