Clinical trials: Prostate Cancer, completed
Prostate Cancer
Detecting Metastases by PyL PET/CT in Subjects Starting Enzalutamide for Untreated Castration Resistant Prostate Cancer.
This study aimed to evaluate the diagnostic performance of 18F-DCFPyL (PyL) PET/CT in subjects presenting not previously treated for castration resistant prostate cancer and showing negative or equivocal findings per…
- Trial name
- PROSTEP-002 (NCT04655365)
- Testing
- Enzalutamide capsule
- Where
- 4 sites in Canada
- Volunteers
- 30 people
- Sponsor
- CHU de Quebec-Universite Laval
Prostate Cancer
Effectiveness of Cryotherapy Study for Prostate Cancer
This is a single-centre prospective, non-randomized trial to investigate the efficacy of cryotherapy in patients with localized prostate cancer.The aim of study is to investigate the safety profile of cryotherapy in the treatment…
- Trial name
- NCT04978519
- Testing
- Cryotherapy
- Where
- Hong Kong
- Volunteers
- 16 people
- Sponsor
- Chinese University of Hong Kong
Biochemically Recurrent Prostate Carcinoma
68Ga-PSMA-11 PET for the Diagnosis of Biochemically Recurrent Prostate Cancer
This phase I trial studies the side effects of 68GA-PSMA-11 PET imaging in patients with prostate cancer that has come back (recurrent).
- Trial name
- NCT04216134
- Testing
- Gallium Ga 68-labeled PSMA-11, Positron Emission Tomography
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer (Adenocarcinoma)
68Ga-P16-093 PET Imaging for Diagnosing Prostate Cancer, a Head-to-head Comparison With mpMRI
68Ga-P16-093 is a novel radiotracer targeting PSMA. In this study, we investigated the diagnostic efficacy of 68Ga-P16-093 PET imaging (PET/CT or PET/MRI) in patients with newly diagnosed, treatment-naive prostate cancer, and…
- Trial name
- NCT07209865
- Testing
- 68Ga-P16-093
- Where
- China
- Volunteers
- 82 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Adenocarcinoma of the Prostate, Stage IIB Prostate Cancer
Intra-operative Optical Imaging With MDX1201-A488 in Patients With Prostate Cancer
This pilot clinical trial studies the best dose of anti-prostate specific membrane antigen (PSMA) monoclonal antibody MDX1201-A488 (MDX1201-A488) given before surgery to aid in visualization of the prostate.
- Conditions
- Adenocarcinoma of the Prostate, Stage IIB Prostate Cancer, Stage III Prostate Cancer, Stage IV Prostate Cancer
- Trial name
- NCT02048150
- Testing
- anti-PSMA monoclonal antibody MDX1201-A488, robot-assisted laparoscopic surgery, diffuse optical imaging
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer, mCRPC
A Phase 1/2 Clinical Trial to Evaluate the Safety, Tolerability, Dosimetry, and Anti-tumor Activity of Ga-68-NGUL / Lu-177-DGUL in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) Refractory to Standard Therapy
This clinical trial is an open-label, single-arm, multi-center, escalation (Phase 1 Part B only), rater-blind (Phase 2 only), phase 1/2 trial to evaluate the diagnostic validity/safety of Ga-68-NGUL and efficacy/safety of…
- Trial name
- NCT05547061
- Testing
- Lu-177-DGUL, Ga-68-NGUL
- Where
- 4 sites in South Korea
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Cellbion Co., Ltd.
Prostate Cancer
Patient and Physician Benefit/ Risk Preferences for Treatment of mPC in Hong Kong: a Discrete Choice Experiment
The objective of this study is to examine the preference weightings in term of risk/ benefit attributes of treatment in physician and prostate cancer patients from different stages of disease.
- Trial name
- NCT05761093
- Where
- Hong Kong
- Volunteers
- 350 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Prostate Cancer
Pilot Study of Secondary Causes of Osteopenia/Osteoporosis in Adults With Breast and Prostate Cancer
The investigators hypothesis is that secondary causes of bone loss are prevalent in patients with breast and prostate cancer, and those patients with secondary causes of bone loss are at higher risk for treatment related bone…
- Conditions
- Breast Cancer, Prostate Cancer, Osteopenia, Osteoporosis
- Trial name
- NCT01277562
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer
Predicting Prostate Biopsy Results With Biomarkers and mpMRI.
Current standard prostate biopsy techniques, used to definitively diagnose prostate cancer (PC), utilises an ultrasound guided biopsy approach, that offers unsatisfactory specificity and sensitivity for clinical significant PC.
- Trial name
- ProBioM (NCT03730324)
- Testing
- mpMRI, Urine and plasma biomarkes.
- Where
- Denmark
- Volunteers
- 261 people
- Sponsor
- Torben Brøchner Pedersen
Prostate Cancer, Urinary Bladder Cancer
Lung US for PEEP Optimization in Robotic Radical Prostatectomy or Cystectomy Patients
There is an increasing trend in the use of robotic-assisted radical prostatectomy or cystectomy (RARPC). Preventing lung atelectasis without inducing overdistention of the lung is challenging.
- Conditions
- Prostate Cancer, Urinary Bladder Cancer, Surgery, Positive End Expiratory Pressure
- Trial name
- NCT06307704
- Testing
- Lung Ultrasound - guided Stepwise PEEP, Standard Ventilation Protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Nazmy Edward Seif
Life-limiting Illness, Breast Cancer
Therapeutic Support to Strengthen Dignity, Mental Well-being and Quality of Life in Acute Palliative Care Patients.
The goal of this clinical trial is to test the benefit of a newly designed personalized therapeutic intervention compared to the standard specialized palliative care service at the swiss acute palliative hospital care.The main…
- Conditions
- Life-limiting Illness, Breast Cancer, Glioblastoma, Prostate Cancer
- Trial name
- NCT06549075
- Testing
- Therapeutic support, Standard Specialized Palliative Consultation Service
- Where
- Switzerland
- Volunteers
- 42 people
- Sponsor
- University Hospital, Basel, Switzerland
Genetic Testing, Breast Cancer
Video Education With Result Dependent dIsclosure
The overall study objective of this trial study is to identify and evaluate strategies to improve the accessibility of the video education with result dependent disclosure (VERDI) model, increasingly utilized as a pre-genetic…
- Conditions
- Genetic Testing, Breast Cancer, Ovarian Cancer, Pancreatic Cancer
- Trial name
- VERDI (NCT05225428)
- Testing
- Video Education, Genetic Counseling
- Where
- United States
- Volunteers
- 1,334 people
- Sponsor
- Dana-Farber Cancer Institute
Prostate Cancer
Nerve-sparing, Robot-assisted Radical Prostatectomy Using a Personalized, 3D-printed Prostate Model for Selective Resection of Positive Surgical Margins
To optimize precision for secondary resection (SR) in frozen section (FS) controlled nerve-sparing robot-assisted radical prostatectomy (NS-RARP) by using a personalized 3D-printed prostate model.
- Trial name
- AURORA (NCT05960669)
- Testing
- 3D model guided secondary resection
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University Hospital, Basel, Switzerland
Prostate Cancer Metastatic, Prostate Cancer Recurrent
Molecular Profiling in Prostate Cancer
We aim to employ targeted DNA NGS to evaluate the prevalence of germline and somatic mutations in cancer predisposing genes, such as BRCA1 and BRCA2, and other HR and DDR genes, including also a few additional clinically relevant…
- Conditions
- Prostate Cancer Metastatic, Prostate Cancer Recurrent, Germline BRCA1 Gene Mutation, Germline BRCA2 Gene Mutation
- Trial name
- ProProstate (NCT04983628)
- Testing
- Tumor molecular profiling
- Where
- Greece
- Volunteers
- 250 people
- Sponsor
- Hellenic Cooperative Oncology Group
Social Determinants of Health, Breast Cancer
Social Risk Factors and Discrimination in Cancer Survivorship
The objective of the proposed study is to scale social risk factor screening and referral for cancer survivors and to solidify information exchange between clinical and community settings in order to improve survivor health and…
- Conditions
- Social Determinants of Health, Breast Cancer, Prostate Cancer, Health Equity
- Trial name
- NCT05301114
- Testing
- Community Health Worker support
- Where
- United States
- Volunteers
- 506 people
- Sponsor
- Medstar Health Research Institute
Prostate Carcinoma
Oral Cryotherapy to Decrease Taste Changes in Prostate Cancer Patients Receiving Taxane Chemotherapy
This clinical trial studies whether cooling the mouth with popsicles (oral cryotherapy) decreases taste changes in prostate cancer patients receiving taxane chemotherapy.
- Trial name
- NCT07218718
- Testing
- Best Practice, Oral Cryotherapy, Survey Administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer, Adenocarcinoma of the Prostate
Nivolumab and BMS-986253 for Hormone-Sensitive Prostate Cancer (MAGIC-8)
MAGIC-8 is a two-arm, multicenter, phase 1b/2 study to assess the efficacy of immunotherapy with either Nivolumab (anti-PD-1) or Nivolumab plus BMS-986253 combined with ADT using Degarelix (LHRH antagonist) for men with…
- Trial name
- NCT03689699
- Testing
- Nivolumab, Degarelix, BMS-986253
- Where
- 4 sites in United States
- Volunteers
- 59 people
- Sponsor
- Mark Stein
Prostate Carcinoma
Evaluation of the Impact of Empty Versus Full Bladder in Patients With Prostate Cancer, RELIEF Trial
This clinical trial evaluates the effects of an empty bladder versus (vs.) a full bladder prior to undergoing a computed tomography (CT) simulation for radiation therapy in patients with prostate cancer.
- Trial name
- NCT06037863
- Testing
- Best Practice, Computed Tomography, Electronic Health Record Review
- Where
- 7 sites in United States
- Volunteers
- 168 people
- Sponsor
- Mayo Clinic
Low Risk Prostate Cancer
Active Surveillance With or Without Apalutamide Treatment in Low Risk Prostate Cancer
Many prostate cancer are slow or non progressive forms that would never impair quality or quantity of like of life if undetected.
- Trial name
- PC-ARN (NCT03088124)
- Testing
- Apalutamide
- Where
- 13 sites in France
- Volunteers
- 93 people
- Sponsor
- Institut Paoli-Calmettes
Prostate Cancer
Multicentric Evaluation of the True Negative Predictive Value of Multiparametric MRI for the Detection of Prostate Cancer Using Cystoprostatectomy Specimen as Reference
To evaluate the negative predictive value of mpMRI in the detection of prostate cancer using cystoprostatectomy specimen as the reference
- Trial name
- NPV-MRI-02 (NCT03960112)
- Testing
- mpMRI
- Where
- 5 sites in France
- Volunteers
- 12 people
- Sponsor
- Institut Paoli-Calmettes