Clinical trials: Prostate Cancer, app or software or digital or wearable or device or sensor
- Condition Prostate Cancer
- Drug or intervention app OR software OR digital OR wearable OR device OR sensor
Hot Flashes, Prostate Cancer
Acupuncture Versus Sham Acupuncture or Usual Care for Antiandrogen-Induced Hot fLashes in Prostate Cancer (AVAIL)
Hot flashes are a common and debilitating symptom among prostate cancer patients undergoing androgen deprivation therapy (ADT). Strong evidence from multiple rigorously designed studies indicated that venlafaxine provides partial…
- Conditions
- Hot Flashes, Prostate Cancer, Acupuncture
- Trial name
- AVAIL (NCT05069467)
- Testing
- Acupuncture
- Where
- 3 sites in China
- Volunteers
- 120 people
- Sponsor
- Guang'anmen Hospital of China Academy of Chinese Medical Sciences
Prostate Cancer (Diagnosis)
Validation of a Platelet Proteomic Assay for Diagnosing and Monitoring Prostate Cancer
This is a single center study evaluating whether a new blood test based on platelet proteins rather than plasma proteins can improve detection of prostate cancer and evaluate the degree of serious disease.
- Trial name
- NCT07144228
- Testing
- HeLP TM
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Duke University
Prostate Cancer
CTC Immune Checkpoint
This pilot study will explore the prevalence of expression of four immune checkpoint biomarkers on circulating tumor cells (CTCs) from men with metastatic prostate cancer that are captured by EpCAM via the CellSearch method, and…
- Trial name
- NCT02456571
- Testing
- CTC biomarker expression prevalence
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Duke University
Prostate Cancer
PET/MRI for Men Being Considered for Radiotherapy for Suspected Prostate Cancer Recurrence Post-Prostatectomy
The PROPS trial is for men being considered for radiotherapy due to the suspicion that their prostate cancer has recurred following the surgical removal of their prostate (prostatectomy).
- Trial name
- PROPS (NCT02131649)
- Testing
- 18F-FCH PET/MRI Scan
- Where
- 10 sites in Australia, Canada and 1 more
- Volunteers
- 99 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Prostate Cancer
68Ga-RM2 for PET/CT of Gastrin Releasing Peptide Receptor (GRPr) Expression in Prostate Cancer
The purpose of this study is to see if a new diagnostic research agent named 68Ga-RM2 can show prostate cancer on a PET/CT scan.
- Trial name
- NCT02559115
- Testing
- 68Ga-RM2 (RM2), PET/CT Scan
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Conditions Influencing Health Status, Healthy
Comparing the Reliability of Expressed Prostatic Secretion (EPS) and Post Massage Urine (PMU) for the Prediction of Prostate Cancer Biopsy Outcome
This randomized pilot phase I trial studies the best way, either expressed prostatic secretion (EPS) or post massage urine (PMU) biomarkers, of predicting biopsy results in patients undergoing prostate biopsy.
- Conditions
- Conditions Influencing Health Status, Healthy, Prostate Cancer
- Trial name
- NCT01441687
- Testing
- laboratory biomarker analysis, transrectal prostate biopsy
- Where
- 5 sites in United States
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Prostate Cancer, Adenocarcinoma
Imperial Prostate 7 - Prostate Assessment Using Comparative Interventions - Fast Mri and Image-fusion for Cancer
To evaluate the role of biparametric MRI and image-fusion targeted biopsies for the detection of prostate cancer. To determine whether biparametric MRI (bpMRI) could be recommended as an alternative to multiparametric MRI (mpMRI)…
- Conditions
- Prostate Cancer, Adenocarcinoma, Prostatic Neoplasms, Prostatic Diseases
- Trial name
- IP7-PACIFIC (NCT05574647)
- Testing
- bpMRI, Image-Fusion targeted and systematic Biopsy
- Where
- 15 sites in United Kingdom
- Volunteers
- 3,600 people
- Sponsor
- Imperial College London
Prostate Cancer
Positioning and Tracking the Prostate During External Beam Radiation
The purpose of this study is to evaluate a non-ionizing electromagnetic method to align the prostate treatment site for radiation therapy and to monitor its position throughout radiation therapy delivery.
- Trial name
- NCT00123838
- Testing
- Calypso® 4D Localization System
- Where
- 5 sites in United States
- Volunteers
- 43 people
- Sponsor
- Varian, a Siemens Healthineers Company
Prostate Cancer, Magnetic Resonance Imaging
Detection of Clinically Significant Prostate Cancer Using Transperineal Targeted Biopsy Compared to Standard Transrectal Biopsy
Prostate biopsies are currently the gold standard for the diagnosis of prostate cancer. Many biopsies, however, are unnecessary or cannot detect significant prostate cancer (PCa).
- Conditions
- Prostate Cancer, Magnetic Resonance Imaging, Target Lesion, Fusion Biopsy
- Trial name
- NCT03044197
- Testing
- MRI/ultrasound transperineal prostate biopsy, transrectal ultrasound-guided prostate biopsy
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Prostate Cancer
Phase 3, Multicenter, Randomized Study, Evaluating the Efficacy and Tolerability of Focused HIFU (High Intensity Focused Ultrasound) Therapy Compared to Active Surveillance in Patients With Significant Low Risk Prostate Cancer
The percentage of malignant prostate tumors detected very early is constantly increasing and the number of well differentiated tumors, with small volume and low risk of progression increases.
- Trial name
- HIFUSA (NCT03531099)
- Testing
- treatment with focal HIFU, PSA dosage, MRI
- Where
- 14 sites in France
- Volunteers
- 108 people
- Sponsor
- Hospices Civils de Lyon
Prostatic Neoplasms
Machine-learning Optimization for Prostate Brachytherapy Planning
The proposed, mono-institutional, randomized-controlled trial aims to determine whether the dosimetric outcomes following prostate Low-Dose-Rate (LDR) brachytherapy, planned using a novel machine learning (ML-LDR) algorithm, are…
- Trial name
- MOPP (NCT02943824)
- Testing
- Machine Learning Planning, Radiation Therapist Planning
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Sunnybrook Health Sciences Centre
Prostate Adenocarcinoma
Prostate Cancer - Localized Adenocarcinoma Proton Therapy
A Phase II Randomized Trial of Hypofractionated Proton Therapy in Patients With A Localized Prostate Adenocarcinoma
- Trial name
- NCT03285815
- Testing
- Proton Therapy
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- National Cancer Center, Korea
Prostate Cancer
Phase II Trial of Focal Cryotherapy for Prostate Cancer
The current standard of care treatment for prostate cancer confined to the prostate is surgical removal or irradiation of the entire prostate gland.
- Trial name
- NCT04138914
- Testing
- Focal Cryotherapy
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Singapore General Hospital
Prostate Cancer
Hyaluronic Acid for Hypofractionated Prostate Radiotherapy
The present Phase II study aims to assess the rates of late rectal toxicities of grade ≥ 2 after hypofractionated radiotherapy of prostate cancer of 62 Gy in 20 fractions of 3.1 Gy with an injection of hyaluronic acid (HA) in the…
- Trial name
- RPAH1 (NCT02165020)
- Testing
- Hyaluronic acid (Macrolane VRF 30®, Q-MED)
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer, Colorectal Cancer (CRC)
Reduce Sedentary Behavior During Cancer Treatment - the RedSedCan Study
Summary Reducing sedentary behavior during treatment is important to reduce the risk of future health problems in individuals undergoing cancer treatment.
- Conditions
- Breast Cancer, Colorectal Cancer (CRC), Prostate Cancer, Neoadjuvant Therapy
- Trial name
- RedSedCan (NCT06719206)
- Testing
- Digital self-management program
- Where
- 2 sites in Sweden
- Volunteers
- 210 people
- Sponsor
- Mälardalen University
Prostatic Neoplasms, Prostatectomy
Evaluating the Effect of the VCD on Erectile Function and Penile Length Post RRP
The purpose of this study is to perform a randomized prospective study to evaluate whether the vacuum erection device facilitates an earlier return of erectile function post radical prostatectomy.
- Trial name
- NCT00177125
- Testing
- ErectAid
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of Minnesota
Prostate Cancer, Recurrent Prostate Cancer
Prostate Specific Membrane Antigen (PSMA) Imaging for Detection of Residual and Metastatic Prostate Cancer
This is a randomized, open-label, pilot study assessing the impact of a short course of bicalutamide on PSMA expression in patients with prostate cancer belonging to the intermediate unfavorable or high risk group, who have low…
- Conditions
- Prostate Cancer, Recurrent Prostate Cancer, Metastatic Prostate Cancer, Prostate Cancer Recurrent
- Trial name
- NCT07593079
- Testing
- Bicalutamide, Prostate-specific membrane antigen Positron Emission Tomography-Computed Tomography, 18F-rhPSMA-7.3
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Washington University School of Medicine
Prostate Cancer
Prostatic Artery Embolization Before Radical Prostatectomy in Prostate Cancer: A Proof-of-concept Study
MRI findings after successful PAE in patients suffering from BPH suggest a complete necrosis of the prostate after this intervention. Thus, PAE might also play a role in the treatment of prostate cancer.
- Trial name
- NCT02917161
- Testing
- Prostatic Artery Embolization (PAE)
- Where
- 2 sites in Switzerland
- Volunteers
- 12 people
- Sponsor
- Dominik Abt
Prostate Cancer
Transrectal Photoacoustic Imaging of the Prostate
The purpose of this study is to image human prostate tissue using a new transrectal photoacoustic imaging probe and correlate this with ultrasound and MRI imaging performed once the specimen has been surgically removed.
- Trial name
- NCT02365883
- Testing
- Photoacoustic Imaging System
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Prostate Lesions
Imaging of Prostate Cancer Using Two-dimensional MR Spectroscopy and Diffusion Tensor Imaging
The goal is to develop MR imaging techniques to improve delineation of cancer extent, and to improve differential diagnosis between prostate cancer and benign prostate hyperplasia or other benign diseases.
- Trial name
- NCT00611065
- Testing
- magnetic resonance imaging
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine