Clinical trials: Prone Position Ventilation
Acute Respiratory Distress Syndrome (ARDS)
Pulmonary Overdistension Assessment With Electrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrom in Prone Position.
Mechanical ventilation in COPD requires a good interaction Patient-Ventilator without asynchronies in order to reduce mortality. Dynamic hyperinflation with PEEPi is responsible for major asynchronies in COPD.
- Trial name
- Tomo-BPCO (NCT07090460)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier de la côte Basque
Acute Respiratory Distress Syndrome in Children
PROSpect: Prone and Oscillation Pediatric Clinical Trial
Severe pediatric acute respiratory distress syndrome (PARDS) is a life-threatening and frequent problem experienced by thousands of children each year.
- Trial name
- NCT03896763
- Testing
- Either supine or prone positioning and either CMV or HFOV
- Where
- 49 sites in United States, Argentina and 13 more
- Volunteers
- 600 people
- Sponsor
- University of Pennsylvania
Prone Positioning, Covid19
Use of Combined Prone Positioning and High-Flow Nasal Cannula, and Non-invasive Positive Pressure Ventilation to Prevent Intubation in COVID-19 Infection
This research aims to understand if prone positioning combined with high-flow nasal cannula (HFNC) or non-invasive positive pressure ventilation (NIPPV) safely reduce the rate of intubation in acute hypoxemic and/or hypercapnic…
- Conditions
- Prone Positioning, Covid19, Hypoxemic Respiratory Failure, ARDS
- Trial name
- NCT04694638
- Testing
- Body position change
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Anesthesia, Surgery
Optimal Positive End-expiratory Pressure (PEEP) in Prone Position During Spine Surgery
Background: There is a lack of studies regarding Optimal (best) positive end-expiratory pressure (PEEP) in prone position during surgery, and its relation with optimal PEEP in supine position.
- Trial name
- OPTIPRONE (NCT04024410)
- Testing
- Evaluation of PEEP in prone position
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Parc de Salut Mar
ARDS, Human, Catheter Infection
Prone Position Impact in ARDS Patients on the Incidence of Central Venous Catheter Colonization
Catheter colonization, catheter-associated infection and catheter-associated bacteremia are a major challenge for resuscitation unit.
- Trial name
- ILCDV (NCT03405038)
- Where
- France
- Volunteers
- 202 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Covid19, Pneumonia, Viral
Hemodynamic Effect of Prone Position in Non-intubated Patient With COVID 19
Prone position in non-intubated patient has shown some respiratory physiological benefits. Prone positioning in patient intubated with ARDS has shown hemodynamic benefits.
- Trial name
- NCT04834947
- Testing
- prone position
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Oxygenation, Driving Pressure
Clinical Impact of Different Duration Prone Postition Treatment for Patients With ARDS.
Acute respiratory distress syndrome (ARDS) is a life-threatening disease, patients with ARDS usually need mechanical ventilation.
- Trial name
- NCT04391387
- Testing
- prone position
- Where
- Taiwan
- Volunteers
- 45 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Investigative Techniques
Study on the Effectiveness and Feasibility of Prone Position Ventilation Technology in Congenital Heart Disease
The purpose of this study was to compare the effects of conventional lying position and prone position ventilation on infants with acute lung injury after surgery for congenital heart disease.
- Trial name
- NCT04607993
- Testing
- Prone position ventilation technique
- Where
- China
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
ARDS, Respiratory Failure
ARDS Esophageal Balloon Pressure Changes With Positioning Study
The use of esophageal balloon catheters, which use esophageal pressure as a surrogate measurement for transpleural pressure, shows promise in improving outcomes of patients with severe acute respiratory distress syndrome (ARDS)…
- Trial name
- NCT03120793
- Testing
- Esophageal balloon catheter
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of North Carolina, Chapel Hill
Pulmonary Function
Pulmonary Function During Prone and Supine Positioning in NICU Infants Requiring Assisted Ventilation
This study seeks to determine in Neonatal Intensive Care Unit (NICU) patients specific improvements in pulmonary function which may occur when an infant is ventilated in the prone as compared to the supine position.
- Trial name
- NCT00749762
- Where
- United States
- Sponsor
- University of Utah
Respiratory Failure With Hypoxia, Respiratory Failure Without Hypercapnia
Prone Positioning During High Flow Oxygen Therapy in Acute Hypoxemic Respiratory Failure
Background High-flow nasal cannula (NHF) are a promising tool for administering oxygen to critically ill patients with high respiratory demand.
- Trial name
- Optiprone (NCT03095300)
- Testing
- Prone position
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Catholic University of the Sacred Heart
Respiratory Distress, Transient Tachypnea of the Newborn
Effect of Supine or Prone Position After Caesarean Birth
Respiratory Distress is a frequent clinical diagnosis of babies delivered by elective Caesarean birth. There has been no study comparing the efficacy of immediately positioning a newly born infant prone vs.
- Conditions
- Respiratory Distress, Transient Tachypnea of the Newborn, Delayed Transition of the Newborn, Persistent Pulmonary Hypertension
- Trial name
- NCT01310153
- Testing
- prone positioning, Supine
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
COVID19, Oxygen Therapy
Impact of Prone Position in Patients Under Spontaneous Breathing on Intubation or Non-invasive Ventilation or Death Incidence During COVID-19 Acute Respiratory Distress
The SARS-Cov2 viral pandemic is responsible for a new infectious disease called COVID-19 (CoronaVIrus Disease), is a major health problem.
- Conditions
- COVID19, Oxygen Therapy, Prone Position, Spontaneous Ventilation
- Trial name
- PROVID-19 (NCT04363463)
- Testing
- prone position
- Where
- 19 sites in France, Monaco
- Volunteers
- 268 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Surfactant Dysfunction
Infants With Severe Acute Respiratory Distress Syndrome: The Prone Trial
The main objective is to determine the short-term effect of prone positioning in infants with infection-associated severe acute respiratory distress syndrome.
- Conditions
- Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS), Surfactant Dysfunction, Infant
- Trial name
- NCT05002478
- Testing
- Prone positioning
- Where
- Austria
- Volunteers
- 14 people
- Sponsor
- Medical University of Vienna
Prone Position, Acute Respiratory Distress Syndrome
Prone Position in infantS/Children With Acute Respiratory Distress Syndrome
In adult patients with acute respiratory distress syndrome (ARDS), the beneficial effects of prone position (PP) have been well investigated and explored; it reduces intrapulmonary shunt (Qs/Qt) and enhances lung recruitment…
- Trial name
- PULSAR (NCT06020404)
- Testing
- supine position, prone position
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
COVID-19
Postural Changes and Severe COVID-19
COVID-19 remains a widespread global epidemic, increasing morbidity, mortality, healthcare resource consumption, and socio-economic burden on patients worldwide.
- Trial name
- NCT05679440
- Testing
- Postural interventions based on pulmonary imaging
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Prone Position, Donors
Prone vs Supine Position in Potential Organ Donors: Multicenter Clinical Trial
Background and justification: In Argentina, 9,650 people are on the organ transplant waiting list, including 290 who require a lung transplant.
- Conditions
- Prone Position, Donors, Lung Procurement, Tissue Donors
- Trial name
- PRODONAR (NCT07251777)
- Testing
- Prone position
- Where
- Argentina
- Volunteers
- 254 people
- Sponsor
- Hospital de Alta Complejidad del Bicentenario Esteban Echeverría
Pulmonary Atelectasis, Postoperative, Postoperative Pulmonary Complications
Ventilation Mode and Atelectasis After Prone-Position Surgery: A Lung Ultrasound Study
This prospective single-centre observational study compared two intraoperative mechanical ventilation modes, volume-controlled ventilation (VCV) and VCV with AutoFlow/AF, in adults undergoing elective surgery in the prone…
- Trial name
- VENTI-PRONE (NCT07680881)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
ARDS, Prone Position
Determine the Effect of Prone Positioning in Adults With ARDS by Electrical Impedance Tomography
determine the effect of prone positioning on ventilation and perfusion distribution in adults with acute respiratory distress syndrome by electrical impedance tomography
- Conditions
- ARDS, Prone Position, Electrical Impedance Tomography
- Trial name
- NCT04725227
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Shanghai Zhongshan Hospital
Acute Respiratory Distress Syndrome
Trans-pulmonary Pressure in ARDS
Adequate PEEP selection in ARDS is still a matter of research. The main objectives of using PEEP in ARDS are improvement in oxygenation, lung recruitment at the end of expiration, prevention of opening and closing of terminal…
- Trial name
- T3P (NCT02416037)
- Testing
- level of positive end expiratory pressure (Prone Proseva), level of positive end expiratory pressure (Prone Talmor)
- Where
- 2 sites in France
- Volunteers
- 32 people
- Sponsor
- Hospices Civils de Lyon