Clinical trials: Prolonged Labor
Prolonged First Stage Labor - Prevention
Best Partograph Action Line to Prevent Prolonged Labour
Objective: To compare active labour outcomes in nulliparous women at term supervised with a partograph with the action line placed at either 2 hours or 4 hours and to determine whether the 2-hour action line placement is better…
- Trial name
- Partograph (NCT02911272)
- Testing
- 2-hour action line on WHO modified partograph, Oxytocin, Forewater amniotomy
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Benin
Membrane Stripping, Cervical Ripening
The SWEEP Trial: a Randomized Controlled Trial
The purpose of this clinical trial is to determine whether serial membrane sweeping at term is more effective than no membrane sweeping in promoting spontaneous onset of labor.
- Conditions
- Membrane Stripping, Cervical Ripening, Memrane Sweeping
- Trial name
- NCT07043088
- Testing
- Membrane sweeping
- Where
- 2 sites in Denmark
- Volunteers
- 1,536 people
- Sponsor
- University of Aarhus
Prolonged First Stage of Labor, Failure of Cervical Dilation as Antepartum Condition
Drotaverine to Shorten the Length of Labor
Reducing the length of labor is a highly desirable goal of intrapartum care, both from a perspective of maternal and fetal well-being, and for the providers of the birth services.
- Conditions
- Prolonged First Stage of Labor, Failure of Cervical Dilation as Antepartum Condition, Labor Pain, Mild Birth Asphyxia, APGAR 4-7
- Trial name
- NCT01639027
- Testing
- Drotaverine
- Where
- Egypt
- Volunteers
- 352 people
- Sponsor
- Ain Shams Maternity Hospital
Prolonged Pregnancy
Outpatient Versus Inpatient Balloon Catheter Induction of Labor
Randomized trial comparing double balloon catheter for induction of labor between in- and outpatient groups.Investigators assess feasibility, clinical effectiveness and patient acceptability of outpatient versus inpatient…
- Trial name
- NCT02793609
- Testing
- Intervention is to let patient to go home., Intervention is to observe women in the ward.
- Where
- Finland
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Prolonged Labor
Amniotomy and Oxytocin for Augmentation of Labour
Prolonged labour is a cause of maternal mortality and morbidity and perinatal mortality and morbidity. Prolonged labour is most often defined as onset of regular , rhythmical painful contractions accompanied by cervical…
- Trial name
- AOAL (NCT02318121)
- Testing
- Amniotomy first, Oxytocin first, Amniotomy and oxytocin
- Volunteers
- 150 people
- Sponsor
- Assiut University
Pregnancy Related, Labor Long
Establish the uSI Values and End-user Training Material That Will be Used to Guide Oxytocin Dosing Actions
Patients receiving oxytocin for induction or augmentation of labor will be studied with uterine EMG. The results of the EMG will be converted to an oxytocin-associated uterine stimulation index (uSI), which is intended to guide…
- Conditions
- Pregnancy Related, Labor Long, Fetal Distress
- Trial name
- uSI-ranges (NCT04548453)
- Testing
- uterine electromyography
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- PreTeL, Inc
Prolonged Labor
Electronic Partograph: A Way of Improving Partograph Use During Labour Monitoring Process in Selected District Hospitals in Bangladesh
Background (brief): 1. Burden: Abnormal prolonged labour and its effects are important contributors to maternal and perinatal mortality and morbidity worldwide.
- Trial name
- NCT03509103
- Testing
- Electronic Partograph
- Volunteers
- 1,012 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Prolonged Second Stage of Labor
Validation of Ultrasound "Angle of Progression" Measurement to Decrease the Cesarean Rate
Ultrasound during labor and measurement of Angle of progression showed extensive prospective and retrospective publications since 2010.
- Trial name
- DELIVERY (NCT05779735)
- Testing
- Transperineal ultrasound measurements of AOP
- Where
- 7 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Prolonged Labour
Can Ultrasound Predict Labor Outcome in Operative Vaginal Deliveries?
To assess whether ultrasound methods can predict outcome of operative vaginal deliveries in nulliparous women at term with singleton pregnancies and prolonged second stage of labor.
- Trial name
- NCT01878591
- Where
- Norway
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Evidence-Based Practice, Labor; Prolonged, Second Stage
Open-glottis Pushing Technique Versus the Valsalva Pushing Technique in the Second Stage of Labor
Pushing has been discussed for decades, primarily in terms of facilitating care in the second stage of labor and maternal/fetal outcomes. Valsalva-type pushing is the pushing performed by a pregnant woman by holding her breath.
- Conditions
- Evidence-Based Practice, Labor; Prolonged, Second Stage, Labor, Fetal Acidosis Complicating Labor and Delivery
- Trial name
- NCT06210087
- Testing
- Spontaneous pushing technique
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Labor Long, Nulliparity
HIDRATA Study: Efficacy of a Hydration Protocol in Nulliparous Women During Labor
Aim. To evaluate the efficacy of optimizing hydration during labor in nulliparous women with respect to reducing the duration of dilation and the second stage of labor, lowering the incidence of Cesarean sections and fever, and…
- Conditions
- Labor Long, Nulliparity, Premature Rupture of Membrane, Pregnancy, Prolonged
- Trial name
- HYDRATA (NCT03607929)
- Testing
- optimal, variability
- Where
- Spain
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Puerta de Hierro University Hospital
Labor Analgesia, Prolonged
Effects of Ropivacaine Concentrations on Prolonged Labor Analgesia
With the changes in medical models and improvements in people's quality of life, parturients have higher demands for childbirth, making the alleviation and elimination of labor pain an important aspect of modern obstetrics.
- Conditions
- Labor Analgesia, Prolonged, Ropivacaine, Concentration
- Trial name
- NCT07007650
- Testing
- High-concentration Ropivacaine, Low concentration ropivacaine group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chengdu Jinjiang Maternity and Child Health Hospital
Lung Diseases, Bronchopulmonary Dysplasia
Prolonged Outcomes After Nitric Oxide (PrONOx)
The purpose of this study is to look at the long term consequences of prematurity in infants treated with inhaled nitric oxide (iNO) while in the neonatal intensive care unit.
- Conditions
- Lung Diseases, Bronchopulmonary Dysplasia, Premature Birth, Developmental Disabilities
- Trial name
- NCT00234247
- Testing
- Long Term Follow-Up
- Volunteers
- 652 people
- Sponsor
- University of Pittsburgh
Body Temperature Changes, Heat Stress
Initial Stay Times and Heat Mitigation Controls for Uncompensable Occupational Heat Stress - Part III
Occupational heat stress directly threatens workers' ability to live healthy and productive lives. Heat exposed workers are at an elevated risk of experiencing impaired work performance and cognitive function leading to a greater…
- Conditions
- Body Temperature Changes, Heat Stress, Heat Exposure, Heat Fatigue
- Trial name
- NCT06630832
- Testing
- Simulated work in the heat with no cooling during rest breaks, Simulated work in the heat with partial cooling during rest breaks, Simulated work in the heat with full cooling during rest breaks
- Where
- Canada
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Labor Stage, Second
The Effect of Ultrasound Guided Visual Biofeedback Performed by Midwifes on the Duration of the Active Second Stage of Labor
The goal of this randomized controlled trial is to investigate whether using of coached sonographic pushing will decrease the length of the second stage of labor and the rate of operative deliveries.
- Trial name
- NCT06857552
- Testing
- Visual biofeedback using transperineal ultrasound (TPUS)
- Where
- Israel
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- Kaplan Medical Center
Pregnancy, Prolonged, Pre Eclampsia
Foley Catheter Versus Vaginal Misoprostol for Cervical Ripening and Induction of Labor
PURPOSE: The purpose of this study is to determine the effectiveness of balloon dilatation (Foley) with vaginal misoprostol for cervical ripening and induction of labor.
- Conditions
- Pregnancy, Prolonged, Pre Eclampsia, Oligohydramnios
- Trial name
- NCT01140971
- Testing
- Misoprostol, Foley
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- Municipal Hospital Vila Nova Cachoeirinha
Labor Long, Labor Pain
Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor
The investigators want to compare the safety and efficacy between the combined spinal-epidural analgesia and epidural analgesia during labor.
- Conditions
- Labor Long, Labor Pain, Labor Fetal Anoxia
- Trial name
- NCT03600272
- Testing
- Combined spinal-epidural analgesia, Epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Prolonged Labor
Effect Of Intravenous Hyoscine -N-Butyl Bromide In Management Of Prolonged Labor In Nulliparous
Women will be admitted when active phase of labour starts defined as the presence of at least three regular uterine contractions over 10 minutes with cervical dilatation four centimeters with cervical effacement not less than 50%…
- Trial name
- NCT03430362
- Testing
- Hyoscine N Butylbromide, Normal Saline 0.9%
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Failed Labor
Prediction of Delivery With Transperineal Ultrasound in Women With Prolonged Labour. Multicentre Study
Objectives 1. To assess if head-perineum distance and angle of progression measured with transperineal ultrasound by the obstetrician on call can predict delivery mode in primiparous women with prolonged first stage of labour. 2.
- Trial name
- NCT01610453
- Testing
- ultrasound examination
- Where
- 6 sites in Denmark, Norway and 2 more
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF