Clinical trials: Prolapse
Breast Ptosis
Evaluation of Safety and Performance of the Orbix Breast Lift System
The study is using a new breast lift system to complement a breast-lift operation. In general there will be recurrence of breast-ptosis after a correcting operation.
- Trial name
- NCT00774059
- Testing
- Breast lift system
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Leiomyoma, Incontinence
Uterine Artery Embolization and Pelvic Floor Symptoms
The objective of this study is to determine whether women who are already receiving treatment for their fibroids (ie. UAE) demonstrate improvement in urinary symptoms and sexual dysfunction as well.
- Conditions
- Leiomyoma, Incontinence, Prolapse
- Trial name
- NCT00827645
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pelvic Organ Prolapse, Normal Pelvic Floor
The 3D Reconstruction Research of Pelvic Organ Prolapse Disease
Female pelvic organ prolapse (FPOP) is one of the main diseases affecting the quality of life of middle aged and elderly women in non-neoplastic diseases.
- Trial name
- NCT03146195
- Testing
- Dynamic Magnetic resonance imaging
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Pelvic Organ Prolapse (POP), Postoperative Pain
Suzetrigine Following Urogynecologic Surgery: Investigation of Postoperative Pain Management
The goal of this clinical trial is to determine whether suzetrigine, when added to standardized multimodal postoperative analgesia improves pain control and reduces opioid consumption after apical suspension surgery for pelvic…
- Conditions
- Pelvic Organ Prolapse (POP), Postoperative Pain, Urogynecology
- Trial name
- SUSI (NCT07856654)
- Testing
- Suzetrigine
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aditi Talkad
Breast Ptosis
A Post-Market Study in Greece of a Minimally Invasive Breast Lift Procedure Utilizing the Renuvion APR System
This is a prospective, non-randomized, single-center, evaluator blinded study of up to 15 subjects undergoing a minimally invasive breast lift procedure utilizing the Renuvion APR System.
- Trial name
- NCT05665335
- Testing
- Renuvion APR System
- Where
- Greece
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Apyx Medical
Pelvic Floor Dysfunctions
Central Sensitization Inventory and Symptoms of Pelvic Floor Dysfunctions
The goal of this observational study is to assess the values of Central Sensitization Inventory in women in a gynecology outpatient clinic.
- Trial name
- NCT07154576
- Where
- Poland
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Żelazna Medical Centre, LLC
Rectal Prolapse
A Modified Technique to Facilitate Pealing of the Rectal Mucosa in Delorme Operation
The aim of this study is to evaluate the investigator new modification for delorme procedure in patients with rectal prolapse , assessing intra-operative morbidity and recurrence rate .
- Trial name
- NCT02901210
- Testing
- Modified delorme procedure
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yasser Mohamed Abdel-samii
Prolapse Genital, Anatomical Pathological Condition
The Change in Vaginal Axis on MRI After Uterus Preserving Laparoscopic Lateral Mesh Suspension
Laparoscopic lateral mesh suspension is emerged as a practical, safe and feasible alternative to sacropexy to treat female genital apical prolapse.
- Trial name
- NCT03772015
- Testing
- Magnetic resonance imaging
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Pelvic Organ Prolapse
Preoperative Analgesia by Infiltration of the Pudendal Nerve Prior to Sacrospinous Ligament Suspension
Pelvic organ prolapse is a common problem. It affects about half of women and causes uncomfortable bulge sensations (similar to sitting on a ball), urine and stool problems, difficulty with sexual activity and embarrassment.
- Trial name
- PAINS (NCT04733560)
- Testing
- Pudendal nerve block, Bupivacaine Injectable Product
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Fraser Health
Epiphora, Ptosis
Bupivacaine Epiphora Trial
The objective of this study is to investigate quantitative improvement in excessive tearing after administration of Bupivacaine, a local anesthetic, into the affected eyelids.
- Trial name
- NCT03266081
- Testing
- 0.75% bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Decisional Conflict
Effect of a Decision Aid on Decision Making for the Treatment of Pelvic Organ Prolapse
Pelvic organ prolapse is a common condition that affects millions of women every year. There are many options for treatment and it can be difficult to make a decision as how best to proceed.
- Trial name
- NCT01798082
- Testing
- Pelvic organ prolapse decision aid
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Urinary Retention, Pelvic Organ Prolapse
Urinary Retention After Removing Urinary Catheter at 24 Hour Versus 48 Hour in Patients With Vaginal Surgery
Comparison incident of urinary retention in patients with vaginal surgery of pelvic organ prolapse, who removed urinary catheter at 24 hours versus 48 hours after surgery
- Trial name
- NCT04954443
- Testing
- Removing urinary catheter
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Urinary Incontinence, Pelvic Organ Prolapse
Promoting Effective Recovery From Labor Urinary Incontinence (PERL)
The purpose of this study is to determine whether pushing during labor that is controlled by the woman results in less birth-related injury and less postpartum urinary incontinence (UI).
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse, Perinatal Laceration, Second Stage Labor
- Trial name
- PERL (NCT00506116)
- Testing
- Videotape, routine care, PME instruction, PME practice and record keeping (in diaries), Non-directed or directed,spontaneous or sustained pushing
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pelvic Organ Prolapse, Stress Urinary Incontinence
Lidocaine for Pessary Check Pain Reduction
The primary objective of this study is to estimate the effect of lidocaine jelly on patient pain at the time of office pessary removal.
- Trial name
- NCT05493735
- Testing
- Lidocaine Hcl 2% Jelly
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Pelvic Organ Prolapse, Surgery
Preoperative Levator Ani Muscle Injection and Pudendal Nerve Block for Pain Control After Vaginal Reconstructive Surgery
To test the hypothesis that preoperative injections along the levator ani muscles and pudendal nerve with bupivacaine and dexamethasone improve pain control after vaginal apical reconstructive surgery.
- Conditions
- Pelvic Organ Prolapse, Surgery, Postoperative Pain
- Trial name
- NCT03040011
- Testing
- Dexamethasone, Bupivacaine, Bilateral Pudendal Nerve Block
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Lauren Giugale, MD
Pelvic Organ Prolapse
Evaluation of Anatomical Results and Sexual Functions After Unilateral and Bilateral Laparoscopic Suture Sacro-hysteropexy Operations
The study was planned as prospective and randomized. For the study, patients will be randomized into two groups as unilateral and bilateral suture sacro-hysteropexy operations.
- Trial name
- NCT06341088
- Testing
- unilateral suture sacro-hysteropexy, bilateral suture sacro-hysteropexy
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery
A Comparison Between Vaginal Sacrospinous Ligament Fixation and Laparoscopic Uterosacral Ligament Suspension as a Uterine Preserving Surgery for Pelvic Organ Prolapse
The investigators present a literature review evaluating the current place of sacrospinous hysteropexy in the surgical management of pelvic organ prolapse.
- Conditions
- Pelvic Organ Prolapse (POP), Pelvic Organ Prolapse Vaginal Surgery, Hysterectomy
- Trial name
- POP-Q USS USLS (NCT06982157)
- Where
- Israel
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Skin Scarring, Eyebrow Ptosis
Use of Botulinum Toxin A in Direct Eyebrow Lift Scar
Prospective, controlled and randomized study in which participants indicated for surgery to direct eyebrow lift will be randomized into two groups.
- Trial name
- NCT06465056
- Testing
- Botulinum toxin type A
- Where
- 2 sites in Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Pelvic Organ Prolapse
Patient Educational Video for Pelvic Organ Prolapse
This is a single-blinded, randomized controlled trial investigating if a patient educational video on pelvic organ prolapse improves patient understanding of this pelvic floor disorder and satisfaction in their healthcare…
- Trial name
- NCT04996563
- Testing
- Video
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Ptosis, Eyelid
Effect of Eyelid Patching After Ptosis Surgery
The goal of this randomized, controlled, observer-blinded study is to compare the effect of compression dressing after ptosis surgery.
- Trial name
- NCT05770973
- Testing
- Compression dressing (build by Kompressen, gauze swabs, Nobamed Paul Danz AG, Wetter, Germany and NOBALUMENAL® - steril, eye pad, Nobamed Paul Danz AG, Wetter, Germany
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Augenklinik LMU