Clinical trials: Progressive Myopia
Myopia, Progressive
Effect of Atropine on Pupil Size and Quality of Vision
This aims to investigated the short-term (12, 16, and 20 h) effects of 0.01% atropine (0.1 mg/ml) on pupil size and subjective quality of vision in participants with myopia.
- Trial name
- NCT06071260
- Testing
- 0.01% atropine eye drop
- Where
- China
- Volunteers
- 40 people
- Sponsor
- He Eye Hospital
Myopia, Progressive
Adverse Events Related to Low Dose Atropine
Progressive myopia can lead to severe vision loss and is associated with retinal detachment, glaucoma, and other comorbidities. Several studies have shown that off-label, low-dose atropine eye drops slow the progression of…
- Trial name
- AELDA (NCT05683535)
- Testing
- Atropine Sulfate
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Scripps Health
Progressive Myopia
MAD Trial: Myopia Atropine Dose
The goal of this interventional study is to compare the efficacy of Atropine 0.05% to Atropine 0.5% treatment against progression of axial length in European children with progressive myopia, and to evaluate the safety…
- Trial name
- MAD (NCT05667454)
- Testing
- Atropine Ophthalmic 0.05%, Atropine Ophthalmic 0.5%
- Where
- 20 sites in Netherlands
- Volunteers
- 550 people
- Sponsor
- Erasmus Medical Center
Myopia, Progressive
Efficacy of IVMED-85 on Pediatric Myopia
The goal of this clinical trial is to evaluate the safety and preliminary efficacy of a 1-year course of IVMED-85 eye drops for the treatment of pediatric myopia by assessing its safety effects on visual acuity and its effect on…
- Trial name
- NCT05761795
- Testing
- IVMED 85
- Volunteers
- 216 people
- Sponsor
- iVeena Delivery Systems, Inc.
Myopia, Hypermetropia
Comparison Between Myopia Versus Hypermetropia With Progressive Addition Lenses in Computer Users
This study examines how myopia (nearsightedness) and hyperopia (farsightedness) affect the use of progressive addition lenses (PALs) for computer users.
- Trial name
- NCT06484257
- Testing
- Myopia, Hypermetropia
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Superior University
Myopia
Progressive Myopia Treatment Evaluation for NaturalVue Multifocal Contact Lens Trial
This is a multi-center, randomized, double-masked clinical trial. All study devices are market approved/cleared in the localities where the study is conducted.
- Trial name
- PROTECT (NCT05159765)
- Testing
- Single vision contact lenses, Multifocal contact lenses
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Myopia, Myopia, Progressive
Myopia Progression With a Novel Extended Depth of Focus Contact Lens
Myopia has been increasing in prevalence and severity throughout the world over the last 30 years. Increasing levels of myopia are associated with increased frequencies and severity of various ocular pathologies, including…
- Trial name
- NCT03358862
- Testing
- NaturalVue Multifocal Contact Lens
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Aller, Thomas A., OD
Myopia, Myopia, Progressive
Kubota Glass Parameter Refinement Study
Length of the eye will be measured in subjects exposed to various stimulus characteristics using an electronic spectacle which presents illuminated targets to the eye.
- Conditions
- Myopia, Myopia, Progressive, Vision Disorders
- Trial name
- NCT06085430
- Testing
- Kubota Glass
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia Progressing
Different Microlenses Array for Controlling Myopia Progression in Children and Adolescents
This study aims to evaluate the effectiveness of lenses with different defocused microlens array in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective defocus microlens…
- Trial name
- NCT06926556
- Testing
- Defocus microlenses
- Where
- China
- Volunteers
- 134 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia Progressing
Light Diffraction Glasses in Preventing and Controlling Myopia in Adolescents
This study aims to evaluate the effectiveness of lenses with light diffraction glasses in controlling the progression of myopia in children and adolescents, and to explore the feasibility of effective design, and apply…
- Trial name
- NCT06927414
- Testing
- Functional lens
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Progressive
Clinical Evaluation of MyoCare in Europe (CEME)
A 2-year prospective, multicenter, randomized controlled, and double-blind clinical trial is used to investigate the efficacy of a new design of ophthalmic lenses to slow the progression of myopia.
- Trial name
- CEME (NCT05919654)
- Testing
- MyoCare, ClearView
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Myopia
Correction of Myopia Evaluation Trial 2
The purpose of the study is to determine if progressive addition lenses (PALs) versus single vision lenses (SVLs) slow the progression of low myopia in children with poor accommodative responses (i.e., large accommodative lags)…
- Trial name
- COMET2 (NCT00320593)
- Testing
- Progressive Addition Lenses (PALs), Single Vision Lenses (SVLs)
- Where
- 8 sites in United States
- Volunteers
- 118 people
- Sponsor
- Jaeb Center for Health Research
Myopia Progressing
Myopia Control With a Innovative Spectacle Lens - A Cessation Study
The purpose of this study is to quantify myopic progression following cessation of a innovative spectacle lenses after 3 years' use.
- Trial name
- NCT06884527
- Testing
- Single Vision Lens to A innovative spectacle lens
- Where
- 5 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopia, Progressive
Effect of Virtual Reality-Based Visual Training for Myopia Control in Children
To assess the efficacy and safety of virtual reality-based visual training (VRVT) in myopia control among children.
- Trial name
- NCT06250920
- Testing
- Virtual reality visual training
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Shanghai 10th People's Hospital
Myopia
Dual-focus Soft Contact Lenses for Controlling Rapid Progressive Myopia in Young Adults
This study aims to evaluate the effectiveness and acceptability of dual-focus soft contact lenses in controlling rapid myopia progression in adults through a randomized controlled trial.
- Trial name
- NCT06528860
- Testing
- MiSight® 1 day soft contact lenses, Proclear® 1 day soft contact lenses
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Effectiveness of 0.01% Atropine Sulfate Solution in Controlling of Myopia Progression in Children
Increasing number of myopic children and significant complications of high myopia enhance the necessity of effective control strategy.
- Trial name
- NCT04338373
- Testing
- 0.01% Atropine sulfate solution in "Comfort Drops" ("AVIZOR S.A.", Spain)
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- The V.P. Vyhodcev Eye Hospital
Myopia, Progressive
To Evaluate the Efficacy and Safety of an Defocus Lens in Slowing the Progression of Myopia
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective, single-centre, randomised, double-blind, controlled, non-inferiority clinical study.
- Trial name
- NCT06405711
- Testing
- frame lens
- Where
- China
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia Progressing, Childhood
Topical 0.01% Atropine for the Control of Fast Progressing Myopia
Myopia prevalence has dramatically increased worldwide in recent years in the general population and among children. Progressive myopia increases gradually with growth until the age of 20-25 years.
- Trial name
- Myopie-STOP (NCT04173780)
- Testing
- Atropine 0.01%
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Myopia, Progressive
Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled Trial
The burden of myopia among Chinese children and adolescents is severe and trending toward younger ages, making control of myopia progression a public health priority.
- Trial name
- NCT07264361
- Testing
- D.D.C dual-control technology spcetacle lenses, Aspheric single-vision lenses
- Where
- China
- Volunteers
- 316 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Myopia, Progressive
Low-dose Atropine for Myopia Control in Children
Myopia (nearsightedness) is the most common eye disorder. Only second to age, it is the main risk factor for major degenerative eye diseases such as glaucoma, macular degeneration or retinal detachment.
- Trial name
- AIM (NCT03865160)
- Testing
- Atropine eye drops, 0.01%, Atropine eye drops, 0.02%
- Where
- 19 sites in Germany
- Volunteers
- 302 people
- Sponsor
- University Eye Hospital, Freiburg