Clinical trials: Program Effectiveness
Ulcerative Colitis
A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)
The purpose of this protocol is to evaluate the efficacy of tulisokibart in participants with moderately to severely active ulcerative colitis.
- Trial name
- NCT06052059
- Testing
- IV Tulisokibart, SC Tulisokibart
- Where
- 476 sites in United States, Argentina and 43 more
- Volunteers
- 1,109 people
- Sponsor
- Merck Sharp & Dohme LLC
Systemic Sclerosis, Face
Efficacy of a Personalized Rehabilitation Program of Facial Involvement in Systemic Sclerosis
Systemic sclerosis is a rare autoimmune disorder characterized by microangiopathy, activation of the immune system, and sclerosis of tissues including the skin. Facial involvement is frequent and disabling.
- Conditions
- Systemic Sclerosis, Face, Facial Involvement, Rehabilitation
- Trial name
- PREVISS (NCT05177380)
- Testing
- Personalized rehabilitation program of facial involvement in systemic sclerosis, Delivery of a standard prescription for facial rehabilitation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Ankylosing Spondylitis
Physical Training Program in Ankylosing Spondylitis
Purpose: to assess the efficacy of a physical training program in patients with ankylosing spondylitis (AS) in a randomized controlled study
- Trial name
- PEPS (NCT02284646)
- Testing
- Personalized physical training program
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Toulouse
Bullying
KiVa Anti-bullying Program in Chile: Evaluation of Effectiveness With and Without the Digital Game Component
Bullying is a major problem worldwide and, with no exception, in Chile. Bullying is defined as a systematic aggressive behavior against a victim who cannot defend himself or herself.
- Trial name
- KiVa-Chile (NCT02898324)
- Testing
- KiVa program
- Volunteers
- 4,485 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Obesity, Bariatric Surgery Candidate
Efficacy of a Mobile Application and Semi-attendance Program in Bariatric Surgery
BACKGROUND: Applications for mobile devices in patients with obesity offer a great opportunity to improve the quality of care and the monitoring of patients in bariatric surgery programs.
- Trial name
- NCT06163235
- Testing
- Obemar platform
- Volunteers
- 72 people
- Sponsor
- Parc de Salut Mar
Trauma Exposure, Trauma
Comparative Effectiveness of SPARCS and Unified Protocol for Youth With Chronic Medical Conditions and Trauma-Related Distress
The goal of this clinical trial is to compare the effectiveness of trauma-focused therapies for improving mental health symptoms and daily functioning in youth with chronic medical conditions who have experienced psychological…
- Conditions
- Trauma Exposure, Trauma, Trauma and Stressor Related Disorder, Mental Health Functioning
- Trial name
- NCT07483333
- Testing
- Structured Psychotherapy for Adolescents Responding to Chronic Stress - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Group, Unified Protocol for Transdiagnostic Treatment of Emotional Disorders in Children and Adolescents - Individual
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Anthony Vesco
Low Back Pain, Muscle Weakness
NASM OPT for Gluteal Enhancement in Non-Athletic Women: An RCT
This RCT evaluates a 12-week NASM OPT program targeting gluteal muscle strength, hip aesthetics (shape, lift, circumference), and low back pain in 120 non-athletic women.
- Conditions
- Low Back Pain, Muscle Weakness, Body Image Disturbance
- Trial name
- GlutealEnhan (NCT06977958)
- Testing
- NASM OPT Group, General Exercise Group
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Sistan and Baluchestan
Male Prison Inmates
The Effects of the GPS Program in Offenders
This randomized controlled trial aimed to assess the efficacy of a 40-session cognitive-behavioral group program, Growing Pro-Social (GPS), in reducing early maladaptive schemas and cognitive distortions (primary outcomes), as…
- Trial name
- GPS (NCT03013738)
- Testing
- Growing Pro-Social Program, Treatment As Usual
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Shoulder Impingement Syndrome, Shoulder Rotator Cuff Tendinopathy
Effectiveness of Supervised Motor Control Exercises on Rotator Cuff Tendinopathies
The shoulder is the most mobile joint in the body but still has the responsibility of ensuring a strong stability of our upper limbs during daily activities.
- Trial name
- NCT02926443
- Testing
- Upper Extremity Neuromuscular Training Program, Usual Physiotherapy Care
- Where
- Canada
- Volunteers
- 33 people
- Sponsor
- Laval University
Cancer
Automated Geriatric Co-Management Program in Older Patients With Solid Mass or Nodule Suspicious for Cancer
The purpose of this study is to find out if it is possible to use the automated geriatric co-management program to manage the participants care before, during and after surgery.
- Trial name
- NCT03885908
- Testing
- in-person geriatric co-management, automated geriatric co-management
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Knee Osteoarthritis
Effect of Physiotherapy After Total Knee Replacement
Physiotherapy plays an important part in rehabilitation after total knee arthroplasty. Even if this is a common practice, few studies have been performed on this issue.
- Trial name
- NCT00807716
- Testing
- walking skill group, usual physiotherapy care
- Where
- Norway
- Volunteers
- 57 people
- Sponsor
- University of Oslo
Whiplash Injuries
University Health Network Whiplash Intervention Trial
Whiplash is the most common traffic injury, affecting 83% of people involved in motor vehicle collisions. People with whiplash injuries often experience pain and disability that can last for a long period.
- Trial name
- WIT (NCT00546806)
- Testing
- Programs of Care
- Where
- 5 sites in Canada
- Volunteers
- 340 people
- Sponsor
- University Health Network, Toronto
Chronic Obstructive Pulmonary Disease, Physical Activity
Efficacy of a Coaching Program to Promote Physical Activity and Reduce Sedentary Behavior After a COPD Hospitalization
Patients with COPD are more inactive and more sedentary than subjects of the same age and patients with other chronic diseases. This inactivity and sedentary behavior is accentuated after hospitalizations due to a COPD…
- Conditions
- Chronic Obstructive Pulmonary Disease, Physical Activity, Sedentary Lifestyle
- Trial name
- NCT03084874
- Testing
- Physical activity and sedentary behavior coaching program
- Where
- Spain
- Volunteers
- 66 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Running-related Injuries
The Effectiveness of a Running-related Injury Prevention Program in Runners
Running is effective in increasing levels of physical activity and promotes a number of beneficial health effects. However, running can lead to running- related injuries (RRI).
- Trial name
- NCT03892239
- Testing
- RunIn3 Prevention Program, Feedback Based Surveillance
- Where
- Brazil
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Universidade Cidade de Sao Paulo
Type 1 Diabetes
Mobile Application-delivered Resistance Program for Children and Adolescents With Type 1 Diabetes (Diactive-1)
This project involves a two-arm randomized controlled trial (RCT) designed to assess the feasibility, acceptability, and preliminary efficacy of a mobile application aimed at prescribing resistance training for children and…
- Trial name
- Diactive-1 (NCT06048757)
- Testing
- Diactive-1 application
- Where
- 2 sites in Spain
- Volunteers
- 62 people
- Sponsor
- Fundacion Miguel Servet
Type 2 Diabetes, Diabetes Mellitus, Type 2
The Effect of a Diabetes Self-management Coaching Program for Type 2 Diabetes Patients in the Ethiopian PC.
Background: Diabetes mellitus is the third most prevalent chronic disease globally. It is a metabolic disorder characterized by elevated blood glucose because of impaired insulin production, reduced insulin effectiveness, or…
- Trial name
- Primarycare (NCT05336019)
- Testing
- Diabetes self-management Coaching, Usual care
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Queen's University
Breast Cancer
Screening for Breast Cancer With Digital Breast Tomosynthesis
Randomized trial comparing the performance of tomosynthesis and 2D Digital Mammography vs 2D Digital Mammography only in respect to incidence of advanced cancers (interval and following round) and interval cancers.
- Trial name
- NCT02698202
- Testing
- Digital Breast Tomosynthesis
- Where
- Italy
- Volunteers
- 26,877 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Migraine Headache
Effectiveness and Acceptability of MINDFULNESS by Smartphone, for Patients with Chronic Migraine and Medication Overuse
Chronic Migraine is a disabling condition that affects the 2% of migraine population. It is often associated with medication overuse that makes this condition very difficult to treat.
- Trial name
- ChroMig-Smart (NCT04389372)
- Testing
- Mindfulness
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Frailty Syndrome
Clinical Intervention in Frail Older People (FRAILCLINIC)
Frailty is the main risk factor for the development of incident disability in older people and one of the most important for other adverse outcomes (death, hospitalisation, falls, and permanent institutionalisation).
- Trial name
- FRAILCLINIC (NCT02643069)
- Testing
- Intervention Geriatric Program
- Where
- Spain
- Volunteers
- 821 people
- Sponsor
- Hospital Universitario Getafe
Knee Arthritis
The Efficacy of Collaborative Patient Education on Total Knee Arthroplasty
This project is about the integrated rehabilitation program for the patients receiving total knee arthroplasty. The investigators are monitoring the WOMAC(Western Ontario and Mcmaster University Arthritis Index)/ Pain…
- Trial name
- NCT05346822
- Testing
- integrated rehabilitation (the collaborative patient education)
- Where
- Taiwan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital