Clinical trials: Progesterone
Contraception, Female Contraception
A Comparative Pharmacokinetic Study of ORTHO EVRA (a Transdermal Contraceptive Patch) and CILEST (an Oral Contraceptive) in Healthy Female Volunteers
The objective of this study is to compare the levels of the hormones norelgestromin, norgestrel, and ethinyl estradiol in the bloodstream of healthy female volunteers administered ORTHO EVRA® (a transdermal contraceptive patch)…
- Trial name
- NCT00254865
- Testing
- EVRA® transdermal contraceptive patch containing 6 mg of norelgestromin and 0.75 mg of ethinyl estradiol (versus CILEST® tablets).
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Infertility
Ulipristal Acetate on Progesterone Levels and Glycodelin-A Endometrial Pattern
Controlled ovarian stimulation (COS) for FIV increases progesterone (P) and estradiol (E2) serum levels in supraphysiologic concentrations at the end of follicular phase.
- Trial name
- NCT01391845
- Testing
- ulipristal acetate
- Where
- Argentina
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Programa de Asistencia Reproductiva de Rosario
Puberty, Hyperandrogenism
Assessment of Day-night Secretion of Progesterone and LH Across Puberty
Hormones are substances that are made by the body and are sent directly out into the bloodstream to increase or decrease the function of certain organs, glands, or other hormones.
- Trial name
- LH (NCT02155933)
- Testing
- Blood sampling
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8
Nipple Aspirate Fluid in Detecting Breast Cancer
This trial studies nipple aspirate fluid in detecting breast cancer. Nipple aspirate fluid may better detect breast cancer earlier than current methods used for screening such as mammograms and breast examinations.
- Conditions
- Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage IIA Breast Cancer AJCC v8
- Trial name
- NCT03715959
- Testing
- Aspiration of Breast, Biospecimen Collection
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Preterm Labor
Utrogestan Versus Nifedipine as Tocolysis for Preterm Labor: a Randomised Controlled Trial
RESEARCH HYPOTHESIS -Incidence of preterm delivery is lower in women treated with oral micronized progesterone (Utrogestan) as acute tocolysis agent compare to Nifedipine group with fewer maternal side effect
- Trial name
- UTROGESTAN (NCT01985594)
- Testing
- utrogestan, Nifedipine
- Where
- Malaysia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- nor zila hassan malek
Healthy
A Study on the Correlation of Drug Metabolism and Human Body Composition Based on the Bioequivalence Trial of Progesterone Sustained-release Vaginal Gel
The aim of this observational study is to investigate the impact of body composition on the absorption, distribution, and metabolism of drugs.
- Trial name
- NCT07097246
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Infertility, Female, Infertility
Is the AMH Intrafollicular Level a Predictor of the Ploidy Status of the Blastocyst?
To investigate, whether on the day of egg retrieval, after ovarian stimulation for ICSI (intracytoplasmic sperm injection), there is a correlation between the intrafollicular AMH (Anti-Müllerian hormone) levels and the ploidy…
- Trial name
- NCT05837325
- Testing
- Oocyte Pick Up - Out of Study, Denudation - Out of Study, ICSI
- Where
- United Arab Emirates
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Menopause, Progesterone
Progesterone and Resting Energy Expenditure
This study evaluates the effect of micronized progesterone substitution in the luteal phase on resting energy expenditure in women during menopausal transition.
- Conditions
- Menopause, Progesterone, Weight Gain
- Trial name
- P4&REE (NCT04140968)
- Testing
- Utrogestan
- Where
- Switzerland
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Gitelman Syndrome, Potassium Depletion
Monocentric STUDY, Randomised Double Blinded (Healthy Subjects, or Transversal (Patients With Gitelman Syndrome)
Progesterone is needed to permit adaptation of the kidney to limit potassium loss in the urines. The investigators wonder whether progesterone or other adrenal hormon play the same role.
- Trial name
- DEPROGE (NCT02297048)
- Testing
- Potassium depletion
- Where
- France
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Estradiol and Progesterone Levels Following Frozen Embryo Transfer
The aim of the present study is to investigate serum estradiol and progesterone levels in women conceiving after natural, estradiol + progesterone or gonadotropin stimulated frozen embryo transfer (FET) cycles.
- Trial name
- ESTRO-FET (NCT04997525)
- Testing
- Estradiol Tablets, Progesterone, Follitropin Alfa
- Where
- Denmark
- Volunteers
- 305 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Infertility, Female, Infertility, Male
Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles
The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.
- Conditions
- Infertility, Female, Infertility, Male, Embryo Transfer, Fertilization in Vitro
- Trial name
- NCT04124913
- Testing
- Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Memorial Sisli Hospital, Istanbul
Estradiol Receptor Polymorphism, Progesterone Receptor Polymorphism
Gene-polymorphisms Relating to Human Subfertility
Estradiol is synthesized by granulosa cells of ovaries under control of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). It is known that Estradiol plays a crucial role in maturation and fertilization of oocytes.
- Conditions
- Estradiol Receptor Polymorphism, Progesterone Receptor Polymorphism, IVF, Subfertility
- Trial name
- NCT01385618
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Ovulation, Menstruation
Impact of Menstrual Phase on Oral Glucose Sensitivity
In this study we are determining whether the hormones associated with the phases of the menstrual cycle (menstruation \& ovulation) influence taste sensitivity to glucose.
- Trial name
- NCT06800690
- Testing
- Urinary Estrogen Level
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tobacco Use Cessation, Tobacco Use Disorder
Progesterone & Postpartum Relapse to Smoking
The primary goal of this project is to investigate the potential efficacy of exogenous progesterone (with supplemental relapse prevention counseling) on postpartum relapse in new mothers.
- Trial name
- NCT01798394
- Testing
- Progesterone
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Healthy
The Effects of Red Wine and White Wine on Blood Estrogen and Progesterone Levels
Healthy pre-menopausal women will be recruited in order to test the effects of red wine and white wine on blood estrogen and progesterone levels.
- Trial name
- NCT00572351
- Testing
- Red Wine, White Wine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Pharmacokinetics
Fasting Bioequivalence Study of 2 Progesterone Soft Capsules 200 mg in 66 Healthy Female Subjects Under Vaginal Route
This study was designed to assess the bioequivalence of Progesterone 200 mg Soft Capsule (JSC "Farmak", Ukraine) versus Utrogestan® 200 mg Soft Capsule (Manufacturer: Cyndea Pharma, S.L., Spain, MAH: Laboratoires Besins…
- Trial name
- NCT05125627
- Testing
- Progesterone 200 mg Soft Capsule (JSC "Farmak", Ukraine), Utrogestan® 200 mg Soft Capsule (Manufacturer: Cyndea Pharma, S.L., Spain, MAH: Laboratoires Besins International, France)
- Where
- Jordan
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
IVF
Efficacy of Micronized Natural Progesterone vs GnRH Antagonist in the Prevention of LH Peak During Ovarian Stimulation.
This study aims to investigate if the use of oral micronized natural progesterone is not inferior to the use of subcutaneous antagonist in preventing LH peak in controlled ovarian stimulation.
- Trial name
- PRO_NAT (NCT05954962)
- Testing
- Progesterone 200 MG, Ganirelix Acetate
- Where
- Spain
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Instituto Bernabeu
Infertility
LH Hormone Pulsation in the Luteal Phase in GnRH Antagonist IVF Cycles Triggered by GnRH Agonist for Final Oocyte Maturation
Monitoring the LH pulsatility during the Luteal phase in GnRH antagonist IVF cycles triggered by GnRH agonist for final oocyte maturation.
- Trial name
- NCT02449642
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pharmacokinetics
A Pharmacokinetic Study to Evaluate the Bioequivalence of 2 Progesterone Vaginal Rings in Postmenopausal Women
A study to assess the pharmacokinetics of 2 progesterone vaginal rings in postmenopausal women
- Trial name
- NCT02092571
- Testing
- Progesterone vaginal ring,
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Healthy
Feasibility Study Into the Contraceptive Effect of Estetrol
This is an open study in 50 young, healthy, female volunteers. Women who want to participate and who are using hormonal contraception stop using their hormonal contraceptive and wait for their first spontaneous menstruation (i.e.
- Trial name
- NCT00563472
- Testing
- estetrol, estetrol and desogestrel, estetrol and progesterone
- Where
- Netherlands
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Pantarhei Bioscience