Clinical trials: Procedural Pain
Procedural Pain
Paternal vs Maternal Holding-Cuddling for Procedural Pain in Healthy Term Neonates
This study investigated the effect of maternal holding-cuddling (MHC) and paternal holding-cuddling (PHC) on heel prick pain and crying duration in healthy term neonates
- Trial name
- NCT06111534
- Testing
- Holding
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Prevention of the Procedural Pain in the Newborn
Prevention of the Procedural Pain in the Newborn
The aim of this study is to compare the impact of two non-medicinal strategies: the breast-feeding and saccharose to measure effects in cerebral cortex during pain using near infrared spectroscopy (NIRS)
- Trial name
- ACTISUCROSE (NCT02109263)
- Testing
- saccharose versus breast-feeding
- Where
- France
- Volunteers
- 114 people
- Sponsor
- University Hospital, Brest
Pain, Procedural
Two Approaches in Enhancing the Efficacy of Inferior Alveolar Nerve Block During Treatment of Mandibular First Permanent Molars With Symptomatic Irreversible Pulpitis
The study is designed as a randomized parallel controlled trial with three groups. Participants aged above 18 years with the first permanent molars with symptomatic signs of irreversible pulpitis will be randomly assigned into 3…
- Trial name
- NCT05427903
- Testing
- Cryotherapy, Buccal local anesthetic infiltration using articaine 4% 1:100000 epinephrine
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Minia University
Pain, Procedural, Pain, Acute
Effect of Reflexology on Pain Management in Newborns
Introduction: Approximately 10-14 painful procedures per day are performed in preterm and term infants during the hospital stay in the first week.
- Conditions
- Pain, Procedural, Pain, Acute, Analgesia
- Trial name
- NCT05235893
- Testing
- Reflexology, Sucrose %24, Kangaroo care
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Marmara University
Catheterization, Central Venous, Pain, Procedural
Comparison of Local Infiltration Anesthesia and Superficial Cervical Plexus Block in Ultrasound-Guided Internal Jugular Vein Catheterization: Efficacy, Duration, and Local Anesthetic Volume
Internal jugular vein (IJV) catheterization is a common invasive procedure performed under ultrasound (USG) guidance. Providing effective analgesia during the procedure is essential for patient comfort.
- Conditions
- Catheterization, Central Venous, Pain, Procedural, Internal Jugular Vein Cannulation
- Trial name
- NCT07841782
- Testing
- Lidocaine HCl 1%
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Kayseri City Hospital
Analgesic Efficacy
Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen
Local anesthetic infiltration is a primary source of acute pain during stereotactic procedures.
- Trial name
- NCT07525219
- Testing
- Suzetrigine, acetaminophen
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Wake Forest University Health Sciences
Diabetic Retinopathy, Diabetic Retinal Disease
Nursing Intervention Based on Stress Adaptation Theory for Patients Undergoing Diabetic Retinal Laser Surgery
This randomized controlled study evaluated whether a nursing intervention based on stress adaptation theory could improve pain trajectory and procedural tolerance in patients undergoing ambulatory retinal laser photocoagulation…
- Trial name
- NCT07544381
- Testing
- Nursing Intervention Based on Stress Adaptation Theory, Routine Peri-Procedural Care
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Joint Shantou International Eye Center of Shantou University and the Chinese University of Hong Kong
Chronic Post-Procedural Pain, Breast Cancer
Evaluation of Persistent Postsurgical Pain After Breast Surgery With a Pectoral Nerves Block (Pecs) Type II
Background and objectives The Pectoral Nerves Block (Pecs) Type II is a regional anesthesia technique that provides post-surgical pain relief for patients undergoing breast surgery.
- Trial name
- NCT03116048
- Testing
- Chronic pain evaluation
- Where
- Belgium
- Volunteers
- 121 people
- Sponsor
- GZA Ziekenhuizen Campus Sint-Augustinus
Misadventure During Injection / Vaccination
The Effect of Stress Ball Use on Procedural Pain Caused by Subcutaneous Injection in Orthopedic Patients
Randomization in the study will be done by the researchers with the Randomizer Research program. The research will be carried out between 01.01.2023 and 01.10.2023 with the participation of 134 patients who were hospitalized in…
- Trial name
- NCT06023485
- Testing
- stress ball use during subcutaneous injection
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Burns, Pain, Procedural
The Effect of Cartoon Character-Printed Band Use During Burn Dressing on Fear, Stress, Pain, and Physiological Parameters in Children: A Randomized Controlled Trial
This randomized controlled trial aims to evaluate the effect of using cartoon character-printed medical bands during burn dressing procedures on children's fear, stress, pain, and physiological parameters.
- Conditions
- Burns, Pain, Procedural, Stress, Psychological, Fear
- Trial name
- CALM-BURN (NCT07313735)
- Testing
- Cartoon-printed band application, Standard band application
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Yuzuncu Yil University
Chest Pain, Pain, Procedural
Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure.
Our study consists of a combination of regional blockade ('local' anesthesia) of the anterior and lateral chest wall in the form of a thin needle prick and the supply of local anesthetic drugs to the area of the relevant chest…
- Conditions
- Chest Pain, Pain, Procedural, Pain, Postoperative, Analgesia
- Trial name
- NCT06520150
- Testing
- Regional anaesthetic combined fascial plane block, Ropivacaine 0.125% Injectable Solution +Lignocaine 0,25% Injectable Solution
- Where
- Poland
- Volunteers
- 32 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Pain Management, Injection Pain Prevention
Testing the Timing and Application of Virtual Reality Distraction During Knee Injections in a VA Pain Clinic
The goal of this clinical trial is to learn whether virtual reality (VR) can be added to routine knee injection appointments at a VA outpatient pain clinic without slowing down or disrupting clinic operations.
- Conditions
- Pain Management, Injection Pain Prevention, Virtual Reality, Feasibility Studies
- Trial name
- NCT07884851
- Testing
- Immersive Virtual Reality
- Volunteers
- 45 people
- Sponsor
- Atlanta VA Medical Center
Post-operative Pain for Total Knee Arthroplasty
Dexmedetomidine for Sedation in Total Knee Replacements
Dexmedetomidine has demonstrated benefits both in sedation, and post-operative pain control, with less respiratory depression than other common sedatives.
- Trial name
- NCT02466022
- Testing
- Dexmedetomidine, Bupivicaine, Normal Saline
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Saskatchewan
Watching a Comedy Video
Effect of Watching a Comedy Video on Anxiety, Pain, Procedural Readiness, and Uroflowmetric Parameters in Patients Undergoing Urodynamic Testing
This study aims to determine the effects of watching a comedy video on anxiety, pain, procedural readiness, and uroflowmetric parameters in patients undergoing urodynamic testing.
- Trial name
- NCT07728903
- Testing
- Watching a comedy video
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Neonatal Pain, Non-Pharmacological Pain Management
Effect of Two Non-pharmacological Method on Pain, Stress Procedure Duration in Newborn
This study is planned as a prospective, single-blind, randomized controlled experimental study matched according to gestational age, gender, and birth weight, to determine the effects of local heat application and oral sucrose…
- Trial name
- NCT07125690
- Testing
- local heat application, oral sucrose, mixed group
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Burns, Pain
Virtual Reality in Burn Pain Management
To examine the safety and efficacy of Virtual Reality (VR) distraction therapy in burn patients experiencing severe procedural pain during wound care.
- Trial name
- NCT00593086
- Testing
- Pain management, Standard of care/no virtual reality game
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- United States Army Institute of Surgical Research
Stable Angina (SA), Unstable Angina (UA)
Breaking Fasts Ahead of Cardiac Caths
The goal of this clinical trial is to find out whether fasting is necessary before urgent inpatient cardiac catheterizations. For patients presenting with urgent heart-related pain or even mild heart attacks, researchers want to…
- Conditions
- Stable Angina (SA), Unstable Angina (UA), NSTEMI - Non-ST Segment Elevation MI
- Trial name
- BACON-RCT (NCT06996639)
- Testing
- Non-Fasting, Fasting
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of South Florida
Bladder Cancer
Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study
The goal of this clinical trial is to learn if certain comfort-enhancing interventions can reduce pain and anxiety during flexible cystoscopy and bladder instillation in patients with bladder cancer.
- Trial name
- Flexi-comfort (NCT07204301)
- Testing
- Optimized Timing of Intravesical Lidocaine Gel, Calming Music During Procedure, Visual Distraction with Screen Content
- Where
- Canada
- Volunteers
- 378 people
- Sponsor
- Western University, Canada
Atrial Septal Defect, Ventricular Septal Defect
Regional Anesthesia Following Pediatric Cardiac Surgery
The purpose of this study is to evaluate pain control following pediatric cardiac surgery with the use of local anesthesia via an ultrasound guided regional anesthetic technique compared with surgeon delivered wound infiltration.
- Conditions
- Atrial Septal Defect, Ventricular Septal Defect, Pain, Procedural
- Trial name
- NCT05688670
- Testing
- Regional Anesthesia, Wound infiltration, Ropivacaine 0.2% Injectable Solution
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Duke University
Procedural Pain, Heel Prick
ShotBlocker and Warm Gel Pack During Neonatal Heel Prick (HEAL)
This study evaluated the effects of ShotBlocker and a warm gel pack on pain, comfort, and physiological parameters during heel prick testing in healthy term newborns.
- Conditions
- Procedural Pain, Heel Prick, Newborn
- Trial name
- HEAL (NCT07686627)
- Testing
- ShotBlocker, Warm Gel Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Marmara University