Clinical trials: Probiotics
Viral Diarrhea
Effect of the Use of Probiotic S. Boulardii on Acute Viral Inflammatory Diarrhea Diagnosed With Multiplex PCR.
Acute diarrhea (AD) has been a public health problem throughout the history of Mexico. According to the epidemiological surveillance system, between 2008-2017, five to six million new cases of AD occurred per year.
- Trial name
- NCT05226052
- Testing
- Saccharomyces boulardii (Floratil 600mg)
- Where
- Mexico
- Volunteers
- 46 people
- Sponsor
- Instituto Mexicano del Seguro Social
Helicobacter Pylori Infection, Dysbiosis
The Efficacy of 10-day and 14-day Bismuth-based Quadruple Therapy in First-line H. Pylori Eradication
Helicobacter pylori (H. pylori) infection is the major cause of gastritis, peptic ulcer disease, and gastric cancer in adults. Bismuth-based quadruple therapy is recommended by a recent review to be the first-line treatment for…
- Conditions
- Helicobacter Pylori Infection, Dysbiosis, Probiotics
- Trial name
- Bsm10 (NCT04527055)
- Testing
- Bismuth Subcitrate 120 MG Oral Tablet, Lactobacillus acidophilus and Bifidobacterium lactis Bb12, Esomeprazole 40mg
- Where
- Taiwan
- Volunteers
- 312 people
- Sponsor
- National Cheng-Kung University Hospital
Functional Abdominal Pain (FAP) in Children
Efficacy of Dietary Supplementation With Lactobacilllus Reuteri DSM 17938 on Functional Abdominal Pain (FAP) in Children
The aim of the study is to investigate the effect of L. reuteri DSM 17938 on pain frequency and severity in children of 5-16 years old and with diagnosis of FAP.
- Trial name
- NCT01719107
- Testing
- L. reuteri DSM 17938 chewable tablets
- Where
- 3 sites in Greece, Poland and 1 more
- Volunteers
- 54 people
- Sponsor
- Aghia Sophia Children's Hospital of Athens
Scleroderma
Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis
Organs of the gastrointestinal tract include the mouth, throat, stomach, intestines, and anus. Patients with scleroderma often have GIT disorders. GIT disorders can be severely debilitating and even life-threatening.
- Trial name
- PRISS (NCT01497743)
- Testing
- Lactobacillus
- Sponsor
- University of Michigan
Black Stains
Investigating the Bactericidal Effect of Probiotics on Chromogenic Bacteria in Children An In Vivo and In Vitro Study
To investigate the bactericidal effect of probiotics (Streptococcus salivarius M18 and Lactobacillus reuteri) on two types of bacteria (Aggregatibacter actinomycetemcomitans and Actinomyces naeslundii) causing black stains of…
- Trial name
- NCT06834815
- Testing
- Probiotic with Prebiotic
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Streptococcus Pyogenes Pharyngotonsillitis
Prophylactic Effect of Probiotic Streptococcus Salivarius eK12 Against Recurrent Streptococcus Pyogenes Pharyngotonsillitis Infection in Pediatrics
Recurrent Group A Streptococcus (GAS) infections, primarily presenting as strep throat, are a significant health concern in pediatric populations, leading to symptoms like sore throat, fever, and swollen lymph nodes.
- Trial name
- NCT06370208
- Testing
- Probiotic Bactoblis® EVOL (Streptococcus salivarius eK12), Oral vit D3
- Where
- 4 sites in Pakistan
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Liaquat University of Medical & Health Sciences
Chronic Kidney Disease (Stages 4 and 5), Peritoneal Dialysis (PD)
Probiotic and Prebiotic Supplementation in Peritoneal Dialysis Patients
The goal of this clinical trial is to learn if synbiotics work to lower inflammation in adults with chronic kidney disease who are on peritoneal dialysis.
- Trial name
- NCT07694791
- Testing
- Synbiotic
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Cardiovascular Diseases, LDL-cholesterol
Evaluation of a Probiotic on LDL-cholesterol Levels
The aim of the present study is to evaluate the ability of Bifidobacterium BSL_PS404 in reducing LDL-cholesterol levels in healthy individuals.
- Trial name
- NCT04029818
- Testing
- Bifidobacterium BSL_PS404
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Chronic Kidney Disease (Stages 3b-5)
Effect of Probiotic Supplementation on Renal Function, Vascular Calcification and Alterations in Bone Mineral Metabolism in Patients With Chronic Kidney Disease
INTRODUCTION You have been asked to participate in a research study of patients with chronic kidney disease to assess whether a probiotic supplement (a commercially available product that is not a medication) can help slow the…
- Trial name
- MICKID (NCT07260682)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Parkinson Disease, Constipation
Effect of Probiotic on Constipation in Patients With Parkinson's Disease
The aim of the study is to collect data for the assessment of the Lactobacillus casei DG (Enterolactis ®duo) effect on constipation and on neuropsychological performance
- Trial name
- NCT04293159
- Testing
- Lactobacillus casei DG (Enterolactis duo®)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Salerno
Irritable Bowel Syndrome
Safety Study of Probiotics in Adults With Irritable Bowel Syndrome
Determine the safety and preliminary effectiveness of VSL#3 in adults with IBS.
- Trial name
- NCT00971711
- Testing
- Probiotic
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- Baylor College of Medicine
Functional Dyspepsia
Probiotics in Functional Dyspepsia
The goal of this clinical trial is to learn whether a multi-strain probiotic can reduce digestive symptoms and improve quality of life in adults with functional dyspepsia.
- Trial name
- ProPepsis (NCT07276009)
- Testing
- Lactobacillus
- Where
- Ukraine
- Volunteers
- 60 people
- Sponsor
- Nordic Biotic Sp. z o.o.
Helicobacter Pylori Infection
Probiotics in the Reduction of Adverse Effects and Dysbiosis of H. Pylori Eradication
The investigators aimed to assess the effect of probiotic supplementation with Vigiis 101-LAB during H. pylori eradication therapy with 14-day sequential therapy in the reduction of adverse effects and the restoration of the…
- Trial name
- NCT03722433
- Testing
- Vigiis 101-LAB and sequential therapy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Gut Resistome
Effect of Probiotics on the Fecal Resistome During Helicobacter Pylori Eradication Therapy
Eradication therapy against Helicobacter pylori (Hp) carries adverse effects, such as altering the intestinal microbiota's structure and function and selecting commensals and pathogens resistant to antibiotics.
- Trial name
- NCT04786938
- Testing
- Saccharomyces Boulardii-Containing Product in Oral Dose Form
- Volunteers
- 72 people
- Sponsor
- Universidad San Francisco de Quito
Mood Disorders, Depression
PROVIT The Influence of Probiotics on Body and Mind in Individuals With Psychiatric Disorders
The aim of this study is to explore the effects of probiotics in individuals with a clinically relevant depression on psychiatric symptoms and cognition, inflammatory parameters, as well as gene-expression.
- Trial name
- NCT03300440
- Testing
- Probiotics and vitamin B7
- Where
- Austria
- Volunteers
- 80 people
- Sponsor
- Medical University of Graz
Irritable Bowel Syndrome, Hypersensitivity
The Effect of a Multispecies Probiotic on Hypersensitivity in Irritable Bowel Syndrome (IBS) Patients
The purpose of this study is to determine whether a specifically designed multispecies probiotic decreases visceral hypersensitivity in IBS-patient (defined by an increased pain tolerance threshold).
- Trial name
- NCT00702026
- Testing
- multispecies probiotic (Ecologic 801)
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- Maastricht University Medical Center
Kidney Failure, Chronic
Effectiveness of Probiotics to Treat End Stage Renal Disease
Intestinal microbiota has recently emerged as an important player in the progression and complications of chronic kidney disease(CKD). And drug therapy which selects the gut as a target has raised lots of concern.
- Trial name
- NCT02929225
- Testing
- Bifid Triple Viable Capsules
- Where
- China
- Volunteers
- 50 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Unexplained Infertility, Endometriosis
Probiotic and Antibiotic Therapies in Women With Unexplained Infertility
The study is designed as a proof of concept pilot study with 3 study arms to evaluate the safety and feasibility of the use of oral probiotics and/or antibiotics in women with unexplained infertility/endometriosis.
- Trial name
- NCT04955574
- Testing
- SH-DS01 + Metronidazole
- Sponsor
- McMaster University
Atopic Dermatitis
Clinical Trial to Evaluate the Effect of a Probiotic Mixture in the Treatment of Atopic Dermatitis in Children
A prospective case-control multicentric pilot study of 12 weeks duration to evaluate the effect of a probiotic mixture in the treatment of atopic dermatitis in children from 0 to 3 years old, by measuring the severity of the…
- Trial name
- NCT05443490
- Testing
- Probiotic mixture with three bacterial strains with maltodextrin as a carrier.
- Where
- 3 sites in Bolivia, Costa Rica and 1 more
- Volunteers
- 4 people
- Sponsor
- Bionou Research, S.L.
Microbiota Analysis in Healthy Subjects
Analysis of the Gut Microbiota Composition After Consumption of Probiotic Bacteria
The goal of this intervention study is to evaluate the beneficial effect of the probiotic bacterium Bacillus coagulans in healthy volunteers.
- Trial name
- NCT07046897
- Testing
- Consumption of probiotics strain 5, Consumption of probiotics strain 6
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lund University