Clinical trials: Primary Prevention
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Primary Health Care, Telemedicine
Proactive Telemedicine to Improve Healthcare Access and Prevention in Rural Primary Care (PTM)
The study evaluates whether Proactive Telemedicine (PTM) can improve healthcare access for individuals who have not contacted their primary care team for at least one year, compared with face-to-face visits.
- Conditions
- Primary Health Care, Telemedicine, Face to Face Consultation, Health Care Access
- Trial name
- PTM (NCT07299201)
- Testing
- Telemedicine Brief Behavioural Lifestyle Intervention, Face to face Brief Behavioural Lifestyle Intervention
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Primary Prevention of Cardiovascular Diseases
Peer-led Digital Health Lifestyle Intervention for a Low Income Community at Risk for Cardiovascular Diseases (MYCardio-PEER)
The goal of this interventional study is to develop and assess the effectiveness of a peer-led digital health program (MYCardio-PEER) for primary prevention of cardiovascular disease (CVD) in a low-income community at-risk of…
- Trial name
- NCT06408493
- Testing
- MYCardio-PEER
- Where
- Malaysia
- Volunteers
- 63 people
- Sponsor
- Monash University Malaysia
Health Behavior, Colorectal Neoplasms
Health Behavior Change in High-Risk Colorectal Cancer Individuals
Background Colorectal cancer is a significant health concern. For individuals identified as being at high risk for developing this disease, adopting healthy lifestyle behaviors is a powerful way to lower that risk.
- Conditions
- Health Behavior, Colorectal Neoplasms, Primary Prevention/Methods
- Trial name
- NCT07262840
- Testing
- Multi-component Health Promotion Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- China Medical University, China
Coronary Artery Disease, Primary Prevention
Effect of the SCOT-HEART 2 Trial on Lifestyle.
This study will recruit 400 participants who are taking part in the Computed Tomography Coronary Angiography for the Prevention of Myocardial Infarction (SCOT-HEART 2) trial.
- Trial name
- NCT04156061
- Testing
- Delivery of CT scan results
- Where
- United Kingdom
- Volunteers
- 400 people
- Sponsor
- University of Edinburgh
Primary/Secondary Prevention, High Risk for Febrile Neutropenia of Chemotherapy Regimens
Efbemalenograstim Alfa for Primary/Secondary Prevention in Patients With Solid Tumors at High Risk for Febrile Neutropenia (FN) or Intermediate Risk of Chemotherapy Regimens Associated With Other Risk Factors in FN
Efbemalenograstim alfa for primary/secondary prevention in patients with solid tumors at high risk for febrile neutropenia (FN) or Intermediate risk of chemotherapy regimens associated with other risk factors in FN
- Conditions
- Primary/Secondary Prevention, High Risk for Febrile Neutropenia of Chemotherapy Regimens, Intermediate Risk of Chemotherapy Regimens Associated With Other Risk Factors in Febrile Neutropenia
- Trial name
- NCT07187908
- Testing
- Efbemalenograstim alfa Injection
- Where
- China
- Volunteers
- 1,076 people
- Sponsor
- Henan Cancer Hospital
Primary Prevention, Vascular Calcification
GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification
A Multicenter, randomized trial comparing the efficacy and safety of intensive lipid-lowering therapy using a statin-ezetimibe combination without aspirin versus statin monotherapy with aspirin in asymptomatic patients with…
- Trial name
- NCT06722521
- Testing
- Pitavastatin 4mg and ezetimibe 10mg, taken once daily, Pitavastatin 2 mg with aspirin 100 mg, taken once daily.
- Where
- South Korea
- Volunteers
- 7,435 people
- Sponsor
- Asan Medical Center
Hypertension, Diabetes Mellitus
Comparison of Intensive Versus Standard Care & Education for Dyslipidemia in Hypertension and Diabetes Patients
The prevalence of dyslipidemia is high among patients with hypertension and diabetes mellitus, which increases the risk of cardiovascular disease.
- Conditions
- Hypertension, Diabetes Mellitus, Dyslipidemia, Primary Prevention
- Trial name
- NCT07045623
- Testing
- centralized management and education group
- Where
- South Korea
- Volunteers
- 348 people
- Sponsor
- Saint Vincent's Hospital, Korea
Coronary Artery Disease, Dyslipidemias
Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention
[Purpose of the Clinical Study]:The purpose of this study is to conduct a clinical comparison of low-dose rosuvastatin plus ezetimibe combination therapy and high-dose rosuvastatin monotherapy in patients with minimal to…
- Conditions
- Coronary Artery Disease, Dyslipidemias, Primary Prevention
- Trial name
- ALMIGHTY (NCT06186037)
- Testing
- Combination drug group of Ezetimibe 10 mg/Rosuvastatin 5 mg, Mono drug group of Rosuvastatin 20 mg
- Where
- South Korea
- Volunteers
- 6,356 people
- Sponsor
- Saint Vincent's Hospital, Korea
Frail Elderly Syndrome, Primary Prevention
Non-pharmacological Prevention of POD in Frailty Elderly Undergoing Elective Surgery Applied by Nursing Teams
The increase in the population over 60 years of age who could receive surgery due to changes in life expectancy and advances in surgical and anesthetic techniques.
- Conditions
- Frail Elderly Syndrome, Primary Prevention, Postoperative Delirium, Frailty
- Trial name
- NPPOD (NCT05993754)
- Testing
- Non-pharmacological intervention
- Where
- Chile
- Volunteers
- 400 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Primary Prevention
Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake
The overarching goal of this project is to implement Boot Camp Translation (BCT) methodology to translate the guidelines and evidence for human papillomavirus (HPV) vaccine into a practice and provider level intervention designed…
- Trial name
- NCT04279964
- Testing
- Boot Camp Translation, Control
- Where
- United States
- Volunteers
- 2,400 people
- Sponsor
- University of Colorado, Denver
Diabetes Mellitus, Foot Ulcer, Diabetic
Prevention of Primary Foot Ulcers in High-risk Diabetes Patients
This is a primary prevention study which aims to assess reduction in the rate of diabetic foot ulcers in patients with high-risk diabetic feet using 3D printed insoles compared to standard care
- Conditions
- Diabetes Mellitus, Foot Ulcer, Diabetic, Primary Prevention
- Trial name
- PROFOUND (NCT03958539)
- Testing
- 3D printed insoles for normal footware
- Where
- United Kingdom
- Volunteers
- 900 people
- Sponsor
- Countess of Chester NHS Foundation Trust
Primary Prevention
New Families- Innovation and Development of the Child Health Services in Oslo
The New Families (NF) program will improve quality of existing services, secure personalised service and early intervention in Child Health Service (CHS) in Oslo.
- Trial name
- NF (NCT04162626)
- Testing
- Supportive home visits to new families, Treatment as usual
- Where
- Norway
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- VID Specialized University
Statin, Cardiovascular Risk Factors
Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor…
- Conditions
- Statin, Cardiovascular Risk Factors, Primary Prevention, Adherence, Medication
- Trial name
- RESPECT2 (NCT05725096)
- Testing
- Coronary Computed Tomography Angiography, Traditional cardiovascular risk stratification
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Zhang longjiang,MD
Emotional Connection, Child Development
CLC Parent-Child Emotional Preparation Program
The purpose of this study is to investigate the feasibility of the Nurture Science Program's (NSP) Drop-In group via telemedicine as standard care at Children's Learning Centers (CLC) to prepare preschoolers emotionally for the…
- Conditions
- Emotional Connection, Child Development, Primary Prevention, Disruptive Behavior
- Trial name
- NCT04626037
- Testing
- WECS Relational Toolkit
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Columbia University
Breast Neoplasm, Primary Prevention
Project Breast47: Effect of an Educational Intervention
Breast cancer is the most frequently diagnosed malignant tumor in women. In 2018, in Spain, the estimated incidence was 101/100,000 women.
- Conditions
- Breast Neoplasm, Primary Prevention, Risk Factors, Telemedicine
- Trial name
- Breast47 (NCT05267171)
- Testing
- Web access
- Where
- Spain
- Volunteers
- 451 people, healthy volunteers welcome
- Sponsor
- University of Oviedo
Primary Prevention
FIT FIRST Teen - School Intervention Study
The goal of this cluster randomised controlled trial is to investigate the effects of the FIT FIRST Teen program on adolescents' physical fitness, motivation, and well-being, as well as the implementation of such a program within…
- Trial name
- NCT06615791
- Testing
- FIT FIRST Teen
- Where
- Denmark
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Primary Prevention, Parenting
The Parental Journey. Digital Tool for Security in Parenthood, a Way to Promote Public Health. A Pilot Study.
The goal of this randomized clinical pilot study is to evaluate the feasibility and experience of the internet-based parental support program "Parenting - a journey together".
- Conditions
- Primary Prevention, Parenting, Family Relations
- Trial name
- NCT06604585
- Testing
- Parenthood - a journey together. Digital tool to increase security in parenthood, a way to promote public health..
- Volunteers
- 30 people
- Sponsor
- Vastra Gotaland Region
Cardiovascular Diseases, Risk Reduction
Strategy for Cardiovascular Disease Prevention Through Tailored Health Management in Individuals With Elevated Risk
The China PEACE SMARTER trial is a cluster ramdomized trial aiming to assess the effectiveness of village doctor-led tailored health management on risk reduction of high-risk individuals for cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Risk Reduction, Primary Prevention
- Trial name
- SMARTER (NCT05645640)
- Testing
- Village doctor-led tailored health management
- Where
- China
- Volunteers
- 4,533 people
- Sponsor
- China National Center for Cardiovascular Diseases
Preeclampsia Severe, Cardiovascular Diseases
Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC)
Women who develop preeclampsia (PE) in pregnancy are at a greater risk for adverse cardiovascular health outcomes. PE is associated with vascular remodeling and functional changes in the postpartum, reflective of its systemic…
- Conditions
- Preeclampsia Severe, Cardiovascular Diseases, Primary Prevention
- Trial name
- PAPVASC (NCT04243278)
- Testing
- Low-dose aspirin
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Dr. Graeme Smith