Clinical trials: Primary Osteoporosis
Healthy, Osteoporosis
Hormone Replacement in Young Women With Premature Ovarian Failure
The human ovary produces male sex hormones (androgen) and female sex hormones (estrogen). Currently, androgen is not included in hormone replacement therapy for women with premature ovarian failure.
- Conditions
- Healthy, Osteoporosis, Premature Ovarian Failure
- Trial name
- NCT00001951
- Testing
- TMTDS
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteoporosis
Effects of Phytoestrogen-rich Diets on Bone Turnover in Postmenopausal Women
Osteoporosis is a major health problem. It was hypothesized that isoflavone-containing products may be a potential alternative to HRT for preventing bone loss during the menopausal transition.
- Trial name
- NCT00301353
- Testing
- Isoflavones-enriched foods
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- TNO
Healthy
The Efficacy of Vitamin K2 n Human Osteoporosis, Blood-vessel Calcification and Sclerosis
This study used the generally recognized as safe (GRAS) grade of Bacillus subtilis natto to produce Vitamin K2, Menaquinone-7(MK-7), via fermentation, for functional evaluation.
- Trial name
- NCT01928134
- Testing
- Vit K2+ Vit D3+ calcium carbonate (CaCO3), Vit K2+CaCO3
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Changhua Christian Hospital
Osteoporosis, Postmenopausal, Osteoporotic Fractures
Evaluation of a Decision Analysis Model in the DASH-Osteo Decision Aid.
Fragility fractures, often caused by low bone mineral density, are a major health concern for postmenopausal women. One way to prevent these fractures is by taking medication, but deciding whether to start treatment can be…
- Conditions
- Osteoporosis, Postmenopausal, Osteoporotic Fractures, Diphosphonates, Fracture Risk Assessment
- Trial name
- DASH-Osteo (NCT07120854)
- Testing
- Decision aid with decision analysis model, Decision aid alone, Usual Care
- Where
- Spain
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Vasomotor Symptoms, Urinary Incontinence
Nurse-led Primary Healthcare Intervention Model in Women's Health Management in Hong Kong
The goal of this randomized clinical trial is to learn if a nurse-led primary healthcare intervention can help improve health management in women adults aged 45 to 64, and to develop an evidence-based primary healthcare model for…
- Conditions
- Vasomotor Symptoms, Urinary Incontinence, Anxiety, Depression - Major Depressive Disorder
- Trial name
- JCDATAZONEWH (NCT06628388)
- Testing
- Nurse-Led Risk-Based 5As Primary Healthcare Model, Minimal Intervention
- Where
- 3 sites in Hong Kong
- Volunteers
- 1,728 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cognitive Impairment, Mood Disorders
Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians
The AGE (Active Geriatric Evaluation) aims to develop a brief assessment tool adapted to the primary care setting.
- Conditions
- Cognitive Impairment, Mood Disorders, Urinary Incontinence, Malnutrition
- Trial name
- NCT01816087
- Testing
- brief geriatric assessment
- Where
- Switzerland
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Acne Vulgaris, Allergic Rhinitis
MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use
The specific aim of this proposed pilot study is to compare two standardized processes (paper and electronic) to deliver a customized MedlinePlus health information prescription.
- Conditions
- Acne Vulgaris, Allergic Rhinitis, Anxiety, Asthma
- Trial name
- NCT01050465
- Testing
- health information prescription
- Volunteers
- 907 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Cardiovascular Diseases, Osteoporosis
A Study on the Impact of Calcium on Woman's Vascular Health
The overarching aim of this randomized clinical trial is to estimate the effect of dietary intake of calcium as compared to supplemental calcium on the vascular system and markers of vascular and bone health in postmenopausal…
- Trial name
- NCT01731340
- Testing
- Calcium Citrate, Low Dietary Calcium, High Dietary Calcium
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Osteoporosis
Calcium and Bone Mass in Young Females
We originally suggested that calcium in the diet is important in determining the amount of bone (bone mass) that builds up in young adults. We are testing the effect of calcium on bone mass in 354 Caucasian (white) girls.
- Trial name
- NCT00000402
- Testing
- Calcium
- Where
- United States
- Volunteers
- 354 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Primary Osteoporosis
Vitamin D Status and Multi-Omics Profiles in Primary Osteoporosis
This observational study aims to explore the relationships between vitamin D status and genomic, proteomic, and metabolomic profiles in patients with primary osteoporosis.
- Trial name
- OP-MultiOmics (NCT07296471)
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dr. Li Chen
Fragility Fracture
Hip Fracture Prevention Follow-up of Elderly Women in Primary Health Care
Researchers plan a 2022 follow-up of medical records data to investigate fracture incidence and survival for 1248 women, born 1902-1931, in a comparative fracture prevention study with 435 participants from an intervention area…
- Trial name
- HIP22 (NCT05269979)
- Testing
- Prevention of hip fractures
- Volunteers
- 1,248 people, healthy volunteers welcome
- Sponsor
- Kronoberg County Council
Family Genetic Characteristics of Osteoporosis
Family Cohort Study on Primary Osteoporosis
Bone metabolism and genetic characteristics of osteoporosis pedigree with kidney-yang deficiency
- Trial name
- NCT05781594
- Where
- 3 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Accidental Falls, Osteoporosis
Prevention of Falls and Its Consequences in Elderly People
Falls are an important risk factor for fragility fractures. Both are associated with the ageing process and as they rise also increase the risk of mortality, disability and dependency.
- Trial name
- PRECIOSA (NCT02617303)
- Testing
- OTAGO's exercises, COMMON PRACTICE
- Where
- 11 sites in Spain
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Osteoporosis in Post-menopausal Women, Prevention
Development of a Wearable Device for Osteoporosis Prevention and Fracture Risk Reduction in Women
This project aims to determine the impact on bone health of: A lifestyle intervention promoting impact-based activities and physical activity for nine months. The same program enhanced with home-based strength training.
- Conditions
- Osteoporosis in Post-menopausal Women, Prevention, Exercise, Physical Activity
- Trial name
- Weapom (NCT06741956)
- Testing
- Weapom Lifestyle Intervention to measure bone impacts using a Fitbit Versa wearable device and the Weapom App.
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Seville
Osteoporosis, Vertebral Fracture
Evaluation of the Impact of a Case-finding Strategy for Vertebral Fractures
Postmenopausal women with vertebral fractures (VFs) represent an important target for secondary fracture prevention, but few of these patients come for clinical attention.
- Trial name
- COSHIBA (NCT00463905)
- Testing
- Clinical assessment +/- radiography
- Where
- United Kingdom
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Bristol
Osteoporosis, Osteopenia
Dried Plums Prevent Inflammation And Improve Bone Health in Osteopenic Men
The goals of this study are 1) to investigate the extent to which dried plum improves bone health by measuring bone density (a measure of bone strength) of whole body, hip, and forearm, indicators of bone formation and bone…
- Trial name
- NCT03408119
- Testing
- Dried Plum, 800 IU vitamin D and 450mg elemental calcium
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Florida State University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Primary Hyperparathyroidism, Bone Diseases, Metabolic
Radius Loading in Primary Hyperparathyroidism
The purpose of the study is to determine the effect of forearm exercise on forearm bone density in post-menopausal women with or without primary hyperparathyroidism.
- Conditions
- Primary Hyperparathyroidism, Bone Diseases, Metabolic, Osteoporosis, Postmenopausal, Bone Loss, Postmenopausal
- Trial name
- NCT01571843
- Testing
- Forearm exercise program, Walking program
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Columbia University
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health