Clinical trials: Primary Insomnia
Insomnia, Primary
Effects of Zero-Time Exercise (ZTEx) on Inactive Adults With Insomnia Disorder
This randomized controlled trial (RCT) with a longitudinal mixed-method process evaluation aims to (1) determine the effectiveness of a ZTEx intervention program, which is a lifestyle-integrated physical activity program, on…
- Trial name
- NCT04227587
- Testing
- Zero Time Exercise, Sleep hygiene education
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The Hong Kong Polytechnic University
Primary Insomnia
Comparison of Efficacy of Behavioral Approaches for Treatment of Insomnia
This study compares the efficacy of four different types (Cognitive Behavior Therapy for Insomnia (CBT-I); Focus of Attention (FOA); Combined CBT-I and FOA; and Sleep Hygiene (control group) for the treatment of insomnia.
- Trial name
- CEBATI (NCT03461666)
- Testing
- Cognitive Behavior Therapy-Insomnia, Focus of Attention, Combined-CBT-I and FOA Group
- Where
- 2 sites in United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Pacific Institute of Medical Sciences
Insomnia Chronic, Insomnia
Effects of Insomnia Treatment on Metabolism in Patients With Depression
This project will examine changes in metabolism and depressive symptoms after receiving CBT-I in 30 subjects with insomnia disorder and MDD.
- Conditions
- Insomnia Chronic, Insomnia, Insomnia, Primary, Depression
- Trial name
- NCT04719143
- Testing
- Cognitive Behavioral Therapy for Insomnia (CBT-I)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pennsylvania
Insomnia, Sleep Deprivation
Study of the Effects of HIRREM-SOP for Insomnia
Prior research studies have shown benefit for use of a technique called High-resolution, relational, resonance-based, electroencephalic mirroring (HIRREM®), to reduce symptoms of moderate to severe insomnia.
- Trial name
- NCT03607994
- Testing
- HIRREM-SOP, NCC
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Insomnia, Primary
Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep
Insomnia is generally believed to be caused by excessive arousal of the brain and body. Rather than transitioning normally and quickly from wakefulness to sleep, individuals with insomnia tend to enter into a self-perpetuating…
- Trial name
- NCT04953559
- Testing
- Active cTBS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Arizona
Primary Insomnia
Digital Cognitive Behavioral Therapy for Insomnia in China
Digital cognitive behavioral therapy for insomnia (dCBT-i) is found to be effective but is rarely used in China. Hence, the investigators developed an automated Chinese dCBT-i program and examined its feasibility, acceptability…
- Trial name
- NCT05416346
- Testing
- Digital Cognitive Behavioral Therapy, Sleep Hygiene Education (SHE)
- Where
- China
- Volunteers
- 217 people
- Sponsor
- Peking University
Primary Insomnia
Effect of Transcranial Direct-current Stimulation Therapy on Primary Chronic Insomnia Patients
To evaluate the clinical efficacy and safety of neuromodulation by transcranial direct current stimulation (tDCS) in the patients with primary chronic insomnia .
- Trial name
- NCT02832804
- Testing
- transcranial Direct Current Stimulation
- Where
- South Korea
- Volunteers
- 8 people
- Sponsor
- Seoul National University Hospital
Primary Insomnia
Effects of Regular Practice of Yoga on Subjective and Objective Sleep Quality in Primary Insomnia
The purpose of the study is to assess the effects of regular Viniyoga in patients suffering from primary insomnia.
- Trial name
- NCT03314441
- Testing
- Yoga
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Insomnia, Primary, Insomnia
Occupation-based Sleep Program for People With Insomnia
Introduction. Sleep problems are a health issue worldwide. Based on the Person-Environment-Occupation-Performance model and the theory of occupational balance, we developed an occupation-based sleep program to address several…
- Trial name
- NCT04940975
- Testing
- Occupation-based sleep intervention program, Insomnia Education Program at Integrated Mental Health Clinic (IMHC)
- Where
- 2 sites in Hong Kong
- Volunteers
- 42 people
- Sponsor
- The Hong Kong Polytechnic University
Insomnia, Primary Insomnia
Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers
The purpose of this study is to learn more about people with insomnia disorder and cognitive impairment. Cognitive impairment is difficulty with mental abilities such as thinking, knowing and remembering.
- Conditions
- Insomnia, Primary Insomnia, Chronic Insomnia
- Trial name
- NCT02290405
- Testing
- Multiple Sleep Latency Test (MSLT)
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Jack Edinger, PhD
Insomnia Comorbid to Psychiatric Disorder, Primary Insomnia
Sequenced Therapies for Comorbid and Primary Insomnias
Chronic insomnia is a prevalent disorder associated with increased health care costs, impaired functioning, and an increased risk for developing serious psychiatric disorders.
- Trial name
- NCT01651442
- Testing
- Behavioral Insomnia Therapy, Zolpidem, Trazodone
- Where
- 2 sites in United States, Canada
- Volunteers
- 211 people
- Sponsor
- Jack Edinger, PhD
Insomnia, Primary
Evaluating an Online Mindfulness-Based Intervention for Insomnia
Insomnia has significantly negative impact on work, quality of life, psycho-somatic health on individuals and imposes substantial economic burdens on society.
- Trial name
- NCT04806009
- Testing
- 'Mindful Living With Insomnia (MLWI)' Intervention via WeChat mini-program, 'Cognitive Behavioral Therapy for insomnia (CBT-I)'via WeChat mini-program
- Volunteers
- 1,000 people
- Sponsor
- Central South University
Primary Insomnia
Efficacy and Safety of 5 mg Sublingual Zolpidem vs 10mg Oral Zolpidem in the Induction and Maintenance of Sleep in Patients With Primary Insomnia
The purpose of this study is to evaluate the efficacy and safety of sublingual zolpidem presentation 5 mg in the induction of sleep in patients with primary insomnia.
- Trial name
- NCT01896336
- Testing
- Zolpidem Hemitartrate
- Where
- Brazil
- Volunteers
- 67 people
- Sponsor
- EMS
Insomnia Chronic, Insomnia, Primary
Exercise and Insomnia Study: The Effects of 1 Week of Exercise Training on Insomnia Severity
It has been hypothesized that exercise may have a beneficial effect on sleep quality and insomnia severity in those who have insomnia symptoms as well as those who meet diagnostic criteria for insomnia disorder (e.g., Diagnostic…
- Trial name
- Insomni-Ex (NCT04402021)
- Testing
- Outdoor Walking, Quiet Rest
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Primary Insomnia
Subjective Study to Assess the Efficacy of APD125 in Patients With Sleep Maintenance Insomnia
This study is designed to compare 2 doses of APD125 (20 mg and 40 mg) with placebo in otherwise healthy adults with primary insomnia primarily with complaints of maintaining sleep.
- Trial name
- NCT00664664
- Testing
- APD125
- Where
- United States
- Volunteers
- 744 people
- Sponsor
- Arena Pharmaceuticals
Depression, Anxiety Disorders
Evaluation of a Group Therapeutic Exercise Program
Moderate to vigorous physical activity can reduce symptoms of mental disorders like major depression, anxiety disorders, insomnia, and ADHD.
- Conditions
- Depression, Anxiety Disorders, Primary Insomnia, ADHD
- Trial name
- NCT03542396
- Testing
- ImPuls
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- University Hospital Tuebingen
Primary Insomnia
Auricular Acupuncture for Primary Insomnia
This double-blind RCT will evaluate the therapeutic effectiveness and safety of auricular acupuncture(AA) for primary insomnia(PI) .
- Trial name
- AAPI (NCT02087488)
- Testing
- auricular acupuncture(AA), Eszopiclone
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Insomnia, Primary
Study of Low Field Magnetic Stimulation (LFMS) on Measures of Sleep
Participants will be recruited and screened through ongoing studies in the sleep and anxiety disorders clinic. Participants with insomnia will be consented to complete several questionnaires, undergo a brief physical exam…
- Trial name
- NCT03050372
- Testing
- LFMS - Active
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Primary Insomnia
Safety and Efficacy Study of Suvorexant in Participants With Primary Insomnia - Study B (MK-4305-029)
This is a multicenter study to test the hypothesis that suvorexant (MK-4305) is superior to placebo in improving insomnia as measured by change from baseline in: subjective total sleep time and time to sleep onset, wake time…
- Trial name
- NCT01097629
- Testing
- Suvorexant High Dose (HD), Suvorexant Low Dose (LD)
- Volunteers
- 1,020 people
- Sponsor
- Merck Sharp & Dohme LLC
Major Depressive Disorder, Primary Hypersomnia
Neurophysiologic Correlates of Hypersomnia
The goal of this project is to examine the neurophysiology of hypersomnia during sleep and wakefulness, to identify biomarkers for excessive sleepiness in neuropsychiatric disorders, and pilot acoustical slow wave induction…
- Conditions
- Major Depressive Disorder, Primary Hypersomnia, Bipolar Disorder, Narcolepsy
- Trial name
- NCT01719315
- Testing
- Acoustical slow wave induction
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison