Clinical trials: Primary Angle Closure
Primary Angle Closure Glaucoma, Primary Angle Glaucoma Closure Suspect
Effect of Multifocal Intraocular Lens on Contrast Sensitivity in Primary Angle-Closure Patients
This prospective study included patients with primary angle-closure (PAC or primary angle-closure glaucoma (PACG) and visually significant cataract.
- Conditions
- Primary Angle Closure Glaucoma, Primary Angle Glaucoma Closure Suspect, Senile Cataract
- Trial name
- NCT04972435
- Testing
- Contrast sensitivity
- Where
- Thailand
- Volunteers
- 35 people
- Sponsor
- Siriraj Hospital
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Malay Glaucoma Eye Study II Navigation, Mobility and Reading Ability in Primary Glaucoma
With the improvement of health system, the life span of Asians has increased tremendously especially in Malaysia. As an early preparation to be an 'aging country' in 2023, Malaysia needs to prepare infrastructure and policy to…
- Trial name
- MaGESII (NCT04736264)
- Testing
- Visual rehabilitation module: navigation and mobility, Visual rehabilitation module: exercise, Visual rehabilitation module: reading
- Where
- Malaysia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma
Prevalence of Ocular Surface Disease in Malaysian Glaucoma Patients
This is a prospective, multi-centre, cross sectional observational study to determine the prevalence of ocular surface disease (OSD) in glaucoma patients, nationwide.
- Conditions
- Primary Open-angle Glaucoma, Primary Angle-Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigment Dispersion Glaucoma
- Trial name
- NCT04609345
- Volunteers
- 400 people
- Sponsor
- Santen Pharma Malaysia Sdn Bhd
Acute Primary Angle-closure Glaucoma
Corneal Densitometry in Acute Primary Angle Closure Glaucoma
Purpose: Our purpose was to investigate the laser peripheral iridotomy (LPI) induced changes in corneal densitometry in acute primary angle closure glaucoma (PACG) cases during the post-laser 1 month period.
- Trial name
- NCT04254458
- Testing
- Corneal densitometry
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Ulucanlar Eye Training and Research Hospital
Primary Angle-Closure Glaucoma, Primary Angle Closure Without Glaucoma Damage
Phacoemulsification Versus Phacoemulsification With Micro-bypass Stent
Assessing the safety and efficacy of a micro-bypass stent in combination with cataract surgery in subjects with primary angle closure.
- Trial name
- NCT03647033
- Testing
- iStent implantation
- Where
- Singapore
- Volunteers
- 32 people
- Sponsor
- Khoo Teck Puat Hospital
Glaucoma, Angle-closure, Primary, Acute
Phase IIA Double-Masked Randomized Sham-Controlled Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Subjects With Acute Primary Angle-Closure Glaucoma (APACG)
This study will assess any side effects that may occur when QPI-1007 is injected into the eye in subjects with acute primary angle-closure glaucoma, as well as how long it takes for the body to clear the drug.
- Trial name
- NCT01965106
- Testing
- QPI-1007 Injection
- Where
- 8 sites in United States, Singapore and 1 more
- Volunteers
- 46 people
- Sponsor
- Quark Pharmaceuticals
Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma
Patch Graft Material Safety and Effectiveness in Covering Glaucoma Drainage Device Tube
The investigators hypothesize that KeraSys is a safe as Tutoplast to cover the tube of the Molteno 3 glaucoma drainage device during surgery
- Conditions
- Primary Open Angle Glaucoma, Primary Angle Closure Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- NCT01301378
- Testing
- Molteno 3 glaucoma drainage shunt
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wills Eye
Primary Angle Closure
Primary Angle Closure Glaucoma and Aqueous Dynamics
The aim of the study is to determine which is the best treatment for people with cataract and primary angle closure (PAC).In PAC, apposition of the iris tissue to the drainage channels (Trabecular Meshwork-TM) of the eye results…
- Trial name
- NCT00719290
- Testing
- Phacoemulsification (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5), Phacoemulsification and goniosynechialysis (Acrylic Foldable Intraocular Lens (Acrysoft)), (Healon5)
- Where
- United Kingdom
- Volunteers
- 24 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Primary Angle Closure Glaucoma
Optical Coherence Tomography Quantitative Analysis of Changes in Anterior Chamber After Laser Peripheral Lridotomy
The purpose of this study is to analysis changes in anterior segment morphology after laser peripheral lrldotomy measured by optical coherence tomography, and to evaluate treatment effectiveness
- Trial name
- NCT02279472
- Testing
- Laserex Tango Nd:YAG, Ellex-SuperQ Medical, Australia
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Xiangya Hospital of Central South University
Glaucoma, Angle-closure, Primary, Acute
Investigating the Neuroprotective Effect of Cop-1 (Copaxone) in Acute Primary Angle Closure
This is a randomised controlled trial to assess the neuroprotective effect of Cop-1 (Copaxone) in patients with acute primary angle closure (APAC).
- Trial name
- NCT01936129
- Testing
- Copaxone
- Where
- Singapore
- Volunteers
- 196 people
- Sponsor
- Singapore Eye Research Institute
Glaucoma, Acute Primary Angle-closure Glaucoma
Comparison of Anterior Chamber Paracentesis and Conventional Mannitol Infusion in Patients With Primary Acute Angle-closure Glaucoma
The investigators wanted to reported the results of immediate anterior chamber paracentesis (ACP), compared to Mannitol infusion, in patients with acute primary angle-closure glaucoma (PACG).
- Trial name
- NCT01266343
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University WanFang Hospital
Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma
Protective Effect of Phenytoin on Glaucoma
since glaucoma is considered an optic neuropathy, new treatments for glaucoma are being continuously investigated, including neuroprotection.
- Conditions
- Primary Open Angle Glaucoma, Secondary Open Angle Glaucoma, Narrow-Angle Glaucomas, Normal Tension Glaucoma
- Trial name
- NCT00739154
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Chronic Angle Closure Glaucoma, Primary Angle Closure
Sequential Laser Iridotomy Using Argon and Q-Switched 532 nm Frequency Doubled Neodymium Yag Laser: A Pilot Study
Sequential Laser Iridotomy uses argon and Nd:yag laser in the first and second steps, respectively. Using q-switched 532 nm laser in the second step is hypothesized to be as good and effective as the conventional Nd:yag laser…
- Conditions
- Chronic Angle Closure Glaucoma, Primary Angle Closure, Primary Angle Closure Suspect, Fellow Eyes of Acute Angle Closure Glaucoma
- Trial name
- NCT00452998
- Testing
- Q-switched fd Nd:yag in Laser Iridotomy
- Where
- Singapore
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Asymptomatic Narrow Angles, Primary Angle Closure Suspects
Asymptomatic Narrow Angles - Laser Iridotomy Study; Multicentric RCT
This is a multicentric, randomised, controlled study comparing Laser Iridotomy (LI) to no treatment in subjects with asymptomatic narrow angles (ANA).One eye of each subject with ANA will be randomised to undergo LI and the other…
- Trial name
- NCT00347178
- Testing
- Laser Peripheral Iridotomy
- Where
- Singapore
- Volunteers
- 544 people
- Sponsor
- Singapore National Eye Centre