Clinical trials: Preventive Medicine
Preterm Delivery, Preterm Contractions
The Impact of Bryophyllum on Preterm Delivery
The purpose of this study is whether Bryophyllum is more effective and has less side effects than traditional labor inhibitors in preventing preterm delivery.
- Conditions
- Preterm Delivery, Preterm Contractions, Cervical Shortening
- Trial name
- NCT00163579
- Testing
- Bryophyllum
- Where
- Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Ischemic Stroke, Hemorrhagic Stroke
Improved Prevention of Stroke in Primary Care in Stockholm, Sweden (Förbättrad Prevention av Stroke)
Stroke is a devastating disease. The acute mortality in Sweden is 20 % and 25 % of all patients relapse. Secondary prevention is proven efficient but observational studies have shown that a number of patients are lost to follow…
- Conditions
- Ischemic Stroke, Hemorrhagic Stroke, TIA, Atrial Fibrillation
- Trial name
- NCT01942031
- Testing
- structured collegial feed back
- Where
- Sweden
- Volunteers
- 204 people
- Sponsor
- Karolinska Institutet
Depression, Healthy
Bone Loss in Premenopausal Women With Depression
The purpose of this study is to determine whether women with major depression lose bone mass at a faster rate than women without depression.
- Conditions
- Depression, Healthy, Osteopenia, Osteoporosis
- Trial name
- NCT00006180
- Testing
- Alendronate
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Coronavirus Infections, Vaccine
An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac)
An Open Comprative Study of the Prophylactic Efficacy and a Non-comparative Study of the Immunogenicity and Safety of the Inactivated Whole-virion Concentrated Purified Coronavirus Vaccine (CoviVac), Produced by FSBSI "Chumakov…
- Trial name
- NCT05407142
- Testing
- CoviVac vaccine (inactivated whole-virion concentrated purified) manufactured by FSBSI "Chumakov FSC R&D IBP RAS", The data from volunteers from the control group
- Where
- 10 sites in Russia
- Volunteers
- 29,000 people, healthy volunteers welcome
- Sponsor
- Chumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products
Cardiomyopathy Due to Drug, Heart Failure, Systolic
Prophylactic Lisinopril to Prevent Anthracycline Cardiomyopathy.
The intent of the study is to show the potential benefits of angiotensin converting enzyme inhibitors in preventing anthracycline induced cardiotoxicity.
- Trial name
- NCT03392740
- Testing
- Lisinopril
- Where
- United States
- Sponsor
- Ascension Health
"Forest Therapy and Mindfulness for Stress Reduction and Well-being in Highly Sensitive Persons (Pilot RCT)"
This study aims to evaluate the effects of Shinrin-Yoku (Forest Bathing) and Forest Medicine interventions on psychological well-being, stress reduction, and overall health outcomes in adults.
- Trial name
- HSP-FOREST (NCT07183917)
- Testing
- Forest Therapy and Mindfulness, Indoor Wellness Control
- Where
- Spain
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- IFM International Forest Medicine
Coronary Heart Disease
Pharmaceutical Follow-up of Coronary Heart Disease (CHD) Patients
Objectives To explore the impact of a clinical pharmacist-led 12 month lasting follow-up program for patients with established coronary heart disease (CHD) discharged from the North Norway University Hospital.
- Trial name
- NCT01115608
- Testing
- Pharmacist follow-up
- Where
- Norway
- Volunteers
- 102 people
- Sponsor
- Hospital Pharmacy of North Norway Trust
Risk Factor, Cardiovascular
Self-screening of Cardiovascular Risk
The aims of this study are (1) to validate a self-screening method for cardiovascular (CV) risk that does not require the supervision of a health professional (including self-measurement of blood pressure, lipid profile evaluated…
- Trial name
- ACRISC (NCT02373319)
- Testing
- CV-screening-1 plus personalized, CV-screening-2 plus personalized, CV-screening-1 plus standard
- Where
- Spain
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Inflammatory Bowel Disease (IBD), CD - Crohn's Disease
Prophylactic Dexamethasone Before Infliximab in Moderate-to-Severe IBD
This comparative observational cohort clinical study aims to investigate the necessity of premedication for allergy prevention prior to infliximab injection, and is designed to evaluate whether non-routine administration of…
- Conditions
- Inflammatory Bowel Disease (IBD), CD - Crohn's Disease, UC - Ulcerative Colitis
- Trial name
- PA (NCT07385131)
- Testing
- Dexamethasone (IV)
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Neoplastic Syndromes, Hereditary
Applying Population Management Best Practices to Preventative Genomic Medicine Trial
Preventive genomic medicine, particularly identification of individuals with inherited cancer risk, can improve longevity and quality of life, yet adherence to risk management following cancer genomic testing is poor.
- Trial name
- CARE-HCS (NCT07053813)
- Testing
- Web resources, Personalized outreach
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Washington
Chronic Hepatitis B
Health Promotion and Management for Hepatitis B Carriers
The investigators propose a project of preventive medicine with concern of local context in Taiwan. The target population includes all staff and faculty members, students, and alumni of a university in Northern Taiwan, with…
- Trial name
- NCT01065363
- Testing
- standardized exercise program and dietary counseling
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Taiwan University Hospital
Hypertension, Dyslipidemia
A Novel Digital Tool Clinicians Can Use to Prescribe Exercise to Patients With Cardiovascular Disease Risk Factors
The investigators will conduct a feasibility and pilot efficacy randomized controlled trial to test the usability and user satisfaction of an evidence-based digital health tool the investigators developed for clinicians to use to…
- Conditions
- Hypertension, Dyslipidemia, Diabetes Mellitus, Obesity
- Trial name
- P3-EX (NCT07238556)
- Testing
- Experimental - 12 Week P3-EX Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants, Active Control - 12 Week ACSM-PAVS Unsupervised Exercise Program with Virtual Weekly Oversight from Graduate Research Assistants
- Where
- 3 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Connecticut
Colorectal Cancer, Gastric Cancer (GC)
Topical Diclofenac for Hand-Foot Syndrome Prevention in Colorectal and Gastric Cancer on Capecitabine (DICLO-HFS)
Hand-foot syndrome (HFS) is a frequent adverse effect of capecitabine, presenting with redness, swelling, pain, and peeling of the skin on the palms and soles.
- Conditions
- Colorectal Cancer, Gastric Cancer (GC), Capecitabine, Hand Foot Syndrome
- Trial name
- DICLO-HFS (NCT07177560)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 151 people
- Sponsor
- Gazi University
Noncommunicable Diseases, Vulnerable Elderly
"Efficiency of Preventive Interventions in Community Nursing to Improve Medication Adherence in Vulnerable Elderly"
The purpose of the study is to design and investigate the effectiveness of a set of preventive interventions by community nurses in outpatient care in treating vulnerable elderly people to improve the extent to which they follow…
- Trial name
- NCT05469581
- Testing
- A set of preventive interventions to improve adherence in vulnerable elderly people
- Where
- Slovenia
- Volunteers
- 639 people
- Sponsor
- Martina Horvat
Bone Pain in Stage I - III Breast Cancer
NOLAN: Naproxen or Loratadine and Neulasta
The primary objective of the study is to estimate the difference in bone pain between breast cancer patients receiving chemotherapy and pegfilgrastim and either no prophylactic intervention, prophylactic naproxen, or prophylactic…
- Trial name
- NOLAN (NCT01712009)
- Testing
- Naproxen, Loratadine, Pegfilgrastim
- Where
- 83 sites in United States
- Volunteers
- 600 people
- Sponsor
- Amgen
Physical Activity
Exercise is Medicine at Emory Seavey Internal Medicine Clinic
Implementation of physical activity promotion in routine health care delivery is low because of multiple barriers including insufficient health system support, care team coordination, and scarcity of community resources for…
- Trial name
- EIM (NCT03416634)
- Testing
- App, Wearable Device, Automated Motivational Message
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Emory University
Substance Abuse, Substance Dependence
fMRI Study of a Dual Process Treatment Protocol With Substance Dependent Adults
The purpose of this study is to determine whether drug-dependent adults who participate in a dual processing relapse prevention treatment protocol that allows for sensory-based exposure experiences over 10-weeks in outpatient…
- Conditions
- Substance Abuse, Substance Dependence, Alcohol Abuse, Drug Use
- Trial name
- NCT01320748
- Testing
- Dual Processing, Relapse Prevention
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Inova Health Care Services
IUD Removal
Use of Ibuprofen to Prevent IUD Site Effects
This research will determine whether prophylactic use of ibuprofen can prevent common side effects of the copper intrauterine device (IUD) and prevent early removal of the device.
- Trial name
- NCT00243815
- Testing
- ibuprofen
- Where
- Chile
- Volunteers
- 2,019 people, healthy volunteers welcome
- Sponsor
- FHI 360
Acute Ischemic Stroke
Association of Prophylactic Use of Stress Ulcer Drugs and Clinical Outcomes in Patients With Acute Anterior Circulation Thrombectomy
Ischemic stroke accounts for a relatively high proportion of strokes. In recent years, intravenous thrombolysis and endovascular therapy have significantly improved the revascularization rate in patients with large vessel…
- Trial name
- NCT05845372
- Where
- 19 sites in China
- Volunteers
- 2,592 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Bronchial Asthma, Genome Wide Association Studies
The Role of Genetic Factors in the Development of Bronchial Asthma in the Kazakh Population
To research for a genetic marker of bronchial asthma, a single nucleotide polymorphism (SNP) analysis of DNA obtained from the peripheral blood of patients with bronchial asthma and normal control will be performed.
- Trial name
- NCT05088512
- Testing
- SNP analysis of the DNA
- Where
- Kazakhstan
- Volunteers
- 300 people
- Sponsor
- Asfendiyarov Kazakh National Medical University