Clinical trials: Preterm Labor
Pulmonary Hypertension, Infant, Premature
Novel Echocardiographic Methods for Early Identification of Neonates at Risk for Chronic Pulmonary Hypertension
Chronic pulmonary hypertension (cPHT) is a serious cardiopulmonary disorder that causes low oxygen levels in the blood, difficulty in breathing and ultimately heart failure.
- Trial name
- NCT04402645
- Where
- 6 sites in United States, Canada and 2 more
- Volunteers
- 350 people
- Sponsor
- Mount Sinai Hospital, Canada
Uterine Septum
Reproductive Outcomes Following Uterine Septum Resection
Nowadays, there is little data to validate the performance of surgical hysteroscopies in the case of septate uterus, particularly in the case of incidental discoveries.
- Trial name
- UTER-SEPTUM (NCT05139446)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Strasbourg, France
Preterm Infant, Birth, Preterm
Aeration, Breathing, Clamping Study 3
Delayed cord clamping (DCC) in preterm infants results in a decrease in mortality and a trend towards fewer intraventricular haemorrhages.
- Trial name
- ABC3 (NCT03808051)
- Testing
- Physiological-based cord clamping, Time-based cord clamping
- Where
- 10 sites in Netherlands
- Volunteers
- 689 people
- Sponsor
- Leiden University Medical Center
Nutrition Disorder, Infant, Music
Lullaby and Classic Music's Effect on Vital Findings and Comfort
In the study, lullabies and classical music played to preterm babies during orogastric tube feeding; It will be tried to determine the effect on cerebral oxygenation level, vital signs and comfort levels.
- Conditions
- Nutrition Disorder, Infant, Music, Preterm, Vital Signs
- Trial name
- NCT05333575
- Testing
- Lullaby, Classic music
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Respiratory Distress Syndrome, Newborn
Thoracic Fluid Content by Electric Bioimpedance Versus Lung Ultrasound in Preterm Neonates With Respiratory Distress
A prospective cohort study aims to evaluate the predictive value of thoracic fluid content measured by electric bioimpedance for detecting the need for surfactant administration or positive pressure ventilation requirement…
- Trial name
- NCT05594030
- Where
- 2 sites in Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Preterm Labor, Tobacco Use Disorder
Omega-3 Fatty Acids for Smoking Cessation in Pregnancy
Smoking is the most important modifiable risk factor for adverse pregnancy outcomes including preterm birth, neonatal death, and maternal complications.
- Trial name
- INFANTS (NCT04417595)
- Testing
- Fish Oil (Containing Omega-3 Acids), Olive Oil
- Where
- United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Preterm, Pain
The Effect of Touch Methods on Pain and Physiological Parameters in Preterm Infants During Endotracheal Aspiration
Recurrent and painful interventions such as heel lancing, venipuncture, dressing change, endotracheal aspiration are frequently performed in neonatal intensive care units (NICU).
- Conditions
- Preterm, Pain, Infant ALL
- Trial name
- NCT05784857
- Testing
- Touch Methods
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Acibadem University
Infant, Premature
Nasogastric Tube in Premature Babies - Pain and Treatment
Does sucrose or pacifier influence pain in premature babies when a nasogastric tube is inserted?
- Trial name
- NCT00218946
- Testing
- Sucrose, Pacifier, sterile water
- Where
- Norway
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Respiratory Distress Syndrome
Cord Blood 25(oh)-Vitamin D Level in Preterm Infants and Associated Morbidities
Experimental and observational studies have shown that vitamin D deficiency may be associated with an increased risk for non-bone diseases and/or abnormal development for the other systems of fetus.
- Trial name
- NCT01812681
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Dr. Sami Ulus Children's Hospital
Stress, Position
The Effect of Positioning With Material and Hand-Face Maneuver
The study was administered in a randomized controlled experimental design to evaluate the effects of material positioning and hand-face maneuver on physiological parameters and stress symptoms in preterm newborns with gestational…
- Trial name
- NCT06136130
- Testing
- Tortoise Positioning Material Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kirsehir Ahi Evran Universitesi
Vaginosis, Bacterial, Abortion, Spontaneous
Bacterial Vaginosis Screening and Treatment to Reduce Infective Complications, Abortion and Preterm Delivery
To determine whether screening of pregnant women with history of previous preterm delivery or with premature contractions for bacterial vaginosis using VS-SENSE, and treatment of positive women will reduce the risk of spontaneous…
- Conditions
- Vaginosis, Bacterial, Abortion, Spontaneous, Premature Birth
- Trial name
- NCT00491270
- Testing
- VS Sense
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Premature Infant, Chronic Respiratory Disease
Genesis Electrical Impedance Tomography (EIT): A Preliminary Study
The purpose of this study is to evaluate the Genesis Electrical Impedance Tomography (EIT) imaging system for use in pediatric respiratory disease populations including neuromuscular and bronchopulmonary dysplasia, as well as in…
- Conditions
- Premature Infant, Chronic Respiratory Disease, Neuromuscular Diseases, Healthy
- Trial name
- NCT03797183
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Preterm Neonate Analgesia
Melatonin As an Analgesic in Preterm Neonate
Melatonin (N-acetyl-5-methoxytryptamine) is a neurohormone secreted by the pineal gland with several important functions, including regulation of the circadian rhythms, antioxidant and anti-inflammatory effects, accumulating…
- Trial name
- NCT05971485
- Testing
- Melatonin 10 mg
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Preterm Labor, Preterm Birth
Cervical Stiffness in Women With Threatened Preterm Labor
Women giving birth prematurely due to spontaneous preterm labor may exhibit signs and symptoms of preterm labor (PTL) which are mostly nonspecific.
- Trial name
- CZECH-TPTL (NCT07840235)
- Testing
- Pregnolia System
- Where
- Czechia
- Volunteers
- 100 people
- Sponsor
- Pregnolia AG
Pregnancy
Pessary to Prevent Prematurity in Twins in Case of Short Cervix
For 25 years, the twin pregnancy rate has regularly increased in the majority of European countries and in the United States, by 35% between 1981 and 2006.
- Trial name
- PESSAR'ONE (NCT02328989)
- Testing
- Pessary
- Where
- 18 sites in France
- Volunteers
- 324 people
- Sponsor
- University Hospital, Toulouse
Sleep Problem, Neurobehavioral Manifestations
NapBiome: Targeting Gut Microbiota and Sleep Rhythm to Improve Developmental and Behavioral Outcomes in Early Childhood
The gut-brain axis plays a crucial role in the regulation and development of psychological and physical processes. The first year of life is a critical period for the development of the gut microbiome, which parallels important…
- Trial name
- NapBiome (NCT06396689)
- Testing
- Synbiotic
- Where
- 2 sites in Switzerland
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Petra Zimmermann
Healthy
Sonographic Prediction of Preterm Delivery Between 24-34 Weeks of Gestation
to evaluate if sonographic measure of short uterin cervix, sludge in amniotic fluid and abnormal doppler of the uterin artery can predict preterm labor
- Trial name
- NCT00613210
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Feeding Intolerance, Premature Birth
Multi-Center Study of Different Doses Domperidone in Feeding Intolerance
The purpose of this clinical multi-center study is to determine whether different doses of domperidone are effective in the treatment of feeding intolerance in premature infant
- Conditions
- Feeding Intolerance, Premature Birth, Domperidone Overdose, Gastric Retention
- Trial name
- MCSDDDFI (NCT02980250)
- Testing
- Low dose, normal dose, over dose
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Sleep
Body Movements Analysis During Sleep in Very Premature Infants
Sleep is a key factor for normal brain development of the newborn. However, it is poorly studied and little is known about its characterization, especially in premature infants.
- Trial name
- DODOPREMA (NCT03432182)
- Testing
- electroencephalography
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Central Hospital, Nancy, France
Preterm Birth, Neonatal Respiratory Distress
Tandem: Skin-to-skin Transfer From the Delivery Room to the Neonatal Unit
Immediate skin-to-skin contact (SSC) is already standard care for healthy term newborns, but its use for term or preterm newborns requiring admission to neonatal unit (NICU) with or without respiratory support is challenging.
- Conditions
- Preterm Birth, Neonatal Respiratory Distress, Mother-Infant Interaction
- Trial name
- Tandem (NCT06198478)
- Where
- Belgium
- Volunteers
- 73 people
- Sponsor
- Erasme University Hospital