Clinical trials: Presbyopia Condition
Presbyopia
Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia
The objective of this study is to evaluate the safety, tolerability, pharmacokinetics, and efficacy of AGN-241622 ophthalmic solution for the first time in human participants
- Trial name
- NCT04403763
- Testing
- AGN-241622, Vehicle
- Where
- 10 sites in United States
- Volunteers
- 80 people
- Sponsor
- AbbVie
Cataract, Presbyopia Correction
Visual Quality and Performance of Eyes With Asqelio™ EDoF Toric Lenses
This study evaluates the optical quality and clinical performance of the Asqelio™ EDOF Toric intraocular lens (IOL) in patients undergoing cataract surgery or refractive lensectomy.
- Trial name
- NCT06707545
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- AST Products, Inc.
Presbyopia
1-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for Presbyopia
Experienced soft contact lens wearing subjects will be enrolled in this 1-week, confirmatory, randomized, bilateral, 2-way crossover, double masked (subject and investigator), repeated measures, dispensing study.
- Trial name
- NCT05325931
- Testing
- kalifilcon A Daily Disposable Multifocal, samfilcon A for Presbyopia
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands
The purpose of this study is to evaluate the use of a multifocal contact lens in people who previously wore contact lenses but discontinued due to age-related, near vision demands.
- Trial name
- GARM (NCT00965237)
- Testing
- lotrafilcon B multifocal contact lens, lotrafilcon B single vision contact lens, Over-reader spectacles
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- CIBA VISION
Presbyopia
Clinical Evaluation of Two Multifocal Contact Lenses
The aim of this study is to evaluate the patient subjective experiences of the monthly multifocal lens when compared to the daily disposable multifocal lens after 15 minutes of daily wear.
- Trial name
- NCT05457608
- Testing
- Lens A, Lens B
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Efficacy and Safety of BRIMOCHOL PF and CARBACHOL PF in Chinese Presbyopia Patients
A multicenter, randomized, double-Blind, crossover, placebo-controlled Phase II clinical Study to evaluate the efficacy and safety of BRIMOCHOL PF and CARBACHOL PF in the treatment of Chinese patients with presbyopia.
- Trial name
- NCT06948357
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Cataract, Lens Opacities
Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Prospective, controlled, single-surgeon, single-center clinical study to compare visual acuity outcomes to data obtained in a similar study by the same principal investigator on the trifocal IOL POD F (study no.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03844828
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Presbyopia
A Study to Evaluate the Safety and Efficacy of EV06 Ophthalmic Solution in Improving Vision in Subjects With Presbyopia
The purpose of this study is to determine whether EV06 Ophthalmic Solution is safe and effective in improving distance corrected near vision in people who have presbyopia.
- Trial name
- NCT02516306
- Testing
- EV06 Ophthalmic Solution
- Where
- 4 sites in United States
- Volunteers
- 75 people
- Sponsor
- Encore Vision, Inc.
Presbyopia
Multifocal Visual Performance Study
The purpose of this trial was to compare the functional visual performance of Precision Profile Multifocal (MF) contact lenses to Progressive Addition Lens (PAL) spectacles in a presbyopic population.
- Trial name
- NCT03757039
- Testing
- Multifocal soft contact lenses, Progressive addition lens spectacles
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 42 people
- Sponsor
- Alcon Research
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Presbyopia
Pilot Clinical Investigation of Adaptative Eyeglasses for the Correction of Presbyopia
This study is a pilot clinical investigation of adaptive eyeglasses for the correction of presbyopia. The goal of this clinical investigation is to assess IMD safety and to obtain patient feedback on the usefulness of the…
- Trial name
- eve-1 (NCT05326607)
- Testing
- Prototype of adaptive eyeglasses, Comparator
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Laclaree
Presbyopia
Multifocal High ADD Contact Lens Proof of Concept Trial
The purpose of this study is to evaluate the visual performance of a new multifocal High ADD contact lens compared to the currently-marketed AIR OPTIX® AQUA MULTIFOCAL (AOAMF) High ADD Contact Lens.
- Trial name
- NCT02117544
- Testing
- Lotrafilcon B multifocal contact lenses (new), Lotrafilcon B multifocal contact lenses
- Volunteers
- 268 people
- Sponsor
- Alcon Research
Presbyopia
Performance of Two Daily Disposable Multifocal Contact Lenses
This study will compare the performance of two daily disposable multifocal soft contact lenses.
- Trial name
- NCT07444658
- Testing
- Lens A (kalfilcon A), Lens B (stenfilcon A)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
A Clinical Comparison of Two Soft Multifocal Contact Lenses
The study objective was to gather short-term clinical performance data for two soft multifocal contact lenses.
- Trial name
- NCT05794126
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- CooperVision, Inc.
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Presbyopia
Safety and Efficacy of an Intrastromal Transform Corneal Allograft (TCA) for Presbyopia Correction - Long Term Follow-up
The objective of this clinical study is to evaluate the long term safety and effectiveness of intrastromal implantation of the Allotex TransForm corneal allograft (TCA) for providing near vision in presbyopic subjects.
- Trial name
- NCT06310252
- Testing
- Opthalmic assessments
- Where
- 7 sites in Czechia, Ireland and 2 more
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Allotex, Inc.
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Cataract, Presbyopia
Post-approval Follow-up Study of the IC-8 Apthera Intraocular Lens (IOL)
The purpose of this study is to evaluate the long-term safety of the IC-8 Apthera intraocular lens (IOL).
- Trial name
- NCT05758883
- Where
- 20 sites in United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia
Evaluation of Safety and Efficacy of Intrastromal Implantation of CorVision® Bioengineered Corneal Inlay for Correction of Presbyopia.
This clinical investigation is a prospective, multicentre, non-comparative case series to assess safety and efficacy of CorVision® bioengineered corneal inlay for improving uncorrected near vision in presbyopic subjects.
- Trial name
- CorVision (NCT04465409)
- Testing
- Intrastromal implantation of CorVision bioengineered corneal inlay for correction of presbyopia.
- Where
- Czechia
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Presbyopia
Safety, Tolerability and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects
A study to Establish Safety, Tolerability, and Efficacy of PresbiDrops (CSF-1) in Presbyopic Subjects.
- Trial name
- NCT02965664
- Testing
- PresbiDrops (CSF-1)
- Where
- 2 sites in Israel
- Volunteers
- 36 people
- Sponsor
- Orasis Pharmaceuticals Ltd.