Clinical trials: Presbyopia,
Presbyopia
Somofilcon A 1-Day Multifocal Study - Real World Subjective Acceptance Study
The objective of the study is to evaluate the performance of somofilcon A 1 day multifocal when worn on a daily disposable wear modality over a period of up to 3 weeks.
- Trial name
- NCT03519919
- Testing
- somofilcon A multifocal lens
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Safety and Efficacy of Nyxol Eye Drops as a Single Agent and With Adjunctive Low-Dose Pilocarpine Eye Drops in Subjects With Presbyopia
The objectives of this study are: To evaluate the safety and efficacy of Nyxol alone and with adjunctive low dose pilocarpine to improve distance-corrected near visual acuity (DCNVA) in subjects with presbyopia.
- Trial name
- VEGA-2 (NCT05646719)
- Testing
- Phentolamine Opthalmic Solution 0.75%, Low dose pilocarpine, Low dose pilocarpine vehicle
- Where
- 26 sites in United States
- Volunteers
- 333 people
- Sponsor
- Opus Genetics, Inc
Cataract, Presbyopia
Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses
The purpose of this study is to compare the binocular distance, intermediate, and near visual acuity of the Alcon Vivity and Bausch \& Lomb enVista IOLs.
- Trial name
- NCT04591054
- Testing
- Extended Vision IOL, Neutral Aspheric Monofocal IOL
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Milton S. Hershey Medical Center
Presbyopia
Multifocal Contact Lens Use in Previous Contact Lens Wearers With Near Vision Demands
The purpose of this study is to evaluate the use of a multifocal contact lens in people who previously wore contact lenses but discontinued due to age-related, near vision demands.
- Trial name
- GARM (NCT00965237)
- Testing
- lotrafilcon B multifocal contact lens, lotrafilcon B single vision contact lens, Over-reader spectacles
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- CIBA VISION
Presbyopia
Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia
The objectives of this study are: To evaluate the efficacy of Nyxol + Pilocarpine to improve DCNVA in subjects with presbyopia
- Trial name
- NCT04675151
- Testing
- Phentolamine Ophthalmic Solution 0.75%, Pilocarpine
- Where
- 17 sites in United States
- Volunteers
- 150 people
- Sponsor
- Opus Genetics, Inc
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Cataract
A Comparison of Visual Function After Bilateral Implantation of Presbyopia-correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with the AcrySof® IQ ReSTOR® +3 versus those bilaterally implanted with the…
- Trial name
- NCT01166971
- Testing
- ReSTOR +3, Tecnis MF
- Where
- 3 sites in United States
- Volunteers
- 65 people
- Sponsor
- Alcon Research
Presbyopia
Multifocal Contact Lenses Fitting Methods Comparison
The purpose of this study was to compare the clinical performance of two fitting approaches for multifocal contact lenses.
- Trial name
- NCT05734846
- Testing
- Control Lenses (control fitting approach), Test Lenses (test fitting approach)
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Presbyopia
Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses
The objective of the study was to compare the lens performance of two daily disposable multifocal contact lenses.
- Trial name
- NCT05763628
- Testing
- Control Lens (stenfilcon A), Test Lens (senofilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- CooperVision, Inc.
Presbyopia
A Single-Center, Double-Masked Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
To evaluate the safety and efficacy of PRX-100 compared with aceclidine alone and vehicle in the treatment of early to moderate presbyopia.
- Trial name
- NCT03201562
- Testing
- Aceclidine+tropicamide combination, Aceclidine, Vehicle
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Presbyopia
Comparison of Two Multifocal Contact Lenses
The purpose of this study is to compare two multifocal contact lenses in presbyopic wearers.
- Trial name
- NCT01250054
- Testing
- Lotrafilcon B contact lens, Comfilcon A contact lens
- Volunteers
- 17 people
- Sponsor
- CIBA VISION
Cataract
Presbyopia-Correcting Intraocular Lenses (IOLs)
The purpose of this study is to prospectively evaluate postoperative visual and refractive parameters in a series of subjects bilaterally implanted with Presbyopia-Correcting Intraocular Lenses (IOLs).
- Trial name
- NCT00963560
- Testing
- ReSTOR +3, Crystalens HD, Crystalens AO
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Alcon Research
Myopia and Hyperopia and Presbyopia
Evaluation of Product Performance of a New Silicone Hydrogel Multifocal Contact Lens
The objective of this study is to evaluate the product performance of a new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens, when worn by…
- Trial name
- NCT05660577
- Testing
- new silicone hydrogel daily disposable multifocal contact lens, the Bausch + Lomb (kalifilcon A) Daily Disposable Multifocal Contact Lens
- Where
- 20 sites in United States
- Volunteers
- 301 people
- Sponsor
- Bausch & Lomb Incorporated
Presbyopia
Safety and Efficacy of AGN-199201 and AGN-190584 in Patients With Presbyopia
A study to evaluate the safety and efficacy of AGN-199201 alone, AGN-190584 alone and concurrent use of AGN-199201 and AGN-190584 in patients with presbyopia (inability to focus for near vision).
- Trial name
- NCT02197806
- Testing
- AGN-199201, AGN-190584, AGN-199201 Vehicle
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Allergan
Presbyopia
A Phase 3 Efficacy Study of Pilocarpine HCl Ophthalmic Solution (AGN-190584) in Participants With Presbyopia
This clinical study will evaluate pilocarpine hydrogen chloride (HCl) ophthalmic solution (AGN-190584) in an expanded participant population to establish efficacy, safety, and tolerability versus the vehicle-control when…
- Trial name
- GEMINI 2 (NCT03857542)
- Testing
- Pilocarpine HCl Ophthalmic Solution, Vehicle
- Where
- 35 sites in United States
- Volunteers
- 427 people
- Sponsor
- Allergan
Presbyopia
Comparison of Two Soft Bifocal Contact Lenses
The purpose of the study is to compare the visual performance of two soft bifocal contact lenses.
- Trial name
- NCT00724945
- Testing
- balafilcon A, senofilcon A
- Where
- 6 sites in United States
- Volunteers
- 113 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Comparison of a Multifocal Contact Lens to a Traditional Multifocal Contact Lens
The purpose of the trial is to compare the performance of two multifocal contact lens systems/products in established presbyopic subjects.
- Trial name
- NCT00886119
- Testing
- Lotrafilcon B multifocal contact lens, Omafilcon A multifocal contact lens
- Volunteers
- 48 people
- Sponsor
- CIBA VISION
Presbyopia
A Study Raindrop Near Vision Inlay in Presbyopes Implanted in Corneal Pockets
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopes implanted in corneal pockets with a delayed or a non-delayed approach.
- Trial name
- NCT03326869
- Testing
- Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Eye Center of North Florida
Astigmatism, Presbyopia
Comparing Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism
The objective of the study was to compare the handling and performance of Biofinity Toric Multifocal to Ultra Multifocal for Astigmatism.
- Trial name
- NCT04404725
- Testing
- comfilcon A, Samfilcon A
- Where
- 7 sites in United States, Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.