Clinical trials: Presbyopia,
Presbyopia
Refitting Multifocal Contact Lens Wearers With a Different Multifocal Contact Lens
The purpose of this study was to compare ease of handling and vision acuity of two multifocal contact lenses to correct presbyopia that are currently CE marked and on the UK market.
- Trial name
- NCT06328660
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia
An Evaluation of the Safety of CSF-1 in Presbyopic Subjects
This is a multi-center, double-masked, vehicle-controlled study. The purpose of the study is to evaluate the safety of CSF-1 compared with vehicle in presbyopic subjects. Subjects will be treated for at least 6 weeks.
- Trial name
- NCT05393895
- Testing
- CSF-1, Vehicle
- Where
- 12 sites in United States
- Volunteers
- 178 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Presbyopia
Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens
This study is a randomized, single-masked, crossover clinical trial. There are two study lenses. Each lens will be dispensed for 3 ± 1 days and then an optimization visit will occur.
- Trial name
- NCT04189224
- Testing
- JJV Investigational Multifocal Contact Lens, 1-Day Acuvue® Moist Brand Multifocal Contact Lens
- Where
- 4 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Presbyopia
Vivity IOL: Emmetropia Compared to Monovision.
Current visual outcomes expectations of cataract patients are similar to those of refractive surgery patients. Their desire is to be spectacle independent for far, intermediate and near vision activities.
- Trial name
- NCT05464732
- Testing
- Vivity IOL emmetropia, Vivity IOL monovision
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Presbyopia
Performance Comparison of Two Monthly Replacement Silicone Hydrogel Multifocal Lens Types
To evaluate and compare the performance of two monthly replacement multifocal contact lenses in existing wearers.
- Trial name
- NCT06232590
- Testing
- Control Lens (comfilcon A), Test Lens (lehfilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia, Myopia
Clinical Investigation iDesign System With 1.3-PRESBY Treatment and STAR S4 IR™ Excimer Laser System
A prospective study to evaluate the feasibility of a new treatment algorithm to increase depth of focus after wavefront-guided LASIK correction of myopic refractive errors with the iDesign Advanced Wavescan Studio™ System and…
- Trial name
- NCT02806726
- Testing
- iDesign 1.3-PRESBY treatment, iDesign 1.3 treatment
- Volunteers
- 42 people
- Sponsor
- Abbott Medical Optics
Aphakia, Cataract
A Clinical Study to Evaluate The Safety and Effectiveness of The RxSight Light Adjustable Lens (LAL) In Subjects Desiring an Extended Depth of Focus
The primary objective of this study is to evaluate, for the visual correction of aphakia and presbyopia, the safety and effectiveness of the RxSight Light Adjustable Lens (LAL) to provide an extended depth of focus (improve…
- Conditions
- Aphakia, Cataract, Presbyopia
- Trial name
- NCT04177771
- Testing
- Light Adjustable lens (LAL) and Light Delivery Device (LDD) - Pre-COVID Population, SofPort LI61AO IOL, Tecnis ZCB00 or ZTC150 IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- RxSight, Inc.
Presbyopia
Extended Depth of Focus Contact Lenses for Presbyopia
VTI has an FDA cleared soft contact lens product. Its optical design creates an enhanced depth of focus (EDOF), which provides clear distance, intermediate, and near vision.
- Trial name
- NCT05495971
- Testing
- NaturalVue Multifocal
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Visioneering Technologies, Inc
Presbyopia
Evaluation of Soft Multifocal Lenses in Presbyopic Previous Contact Lens Wearers
To explore the wear experience in Dailies TOTAL1 Multifocal contact lenses in presbyopic adults who have previously dropped out of contact lens wear.
- Trial name
- NCT06053463
- Testing
- Daily disposable multifocal soft contact lens
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jennifer Fogt
Presbyopia
Safety and Efficacy Study BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic or Pseudophakic Presbyopia
Safety and Efficacy Study of BRIMOCHOL™ PF and Carbachol PF in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia
- Trial name
- NCT05270863
- Testing
- BRIMOCHOL™ PF, Carbachol PF, Brimonidine tartrate
- Where
- 15 sites in United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Visus Therapeutics
Presbyopia
A Study to Assess the Impact and Adverse Events of Topical Eyedrops of AGN-190584 on Night-driving Performance in Participants, 40 to 55 Years of Age
The purpose of this study is to evaluate night-driving performance in real-world driving conditions in participants with presbyopia treated with AGN-190584 versus vehicle.
- Trial name
- NCT04837482
- Testing
- AGN-190584, Vehicle
- Where
- Australia
- Volunteers
- 43 people
- Sponsor
- AbbVie
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine/Brimonidine (LNZ101) and Aceclidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05294328
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle Proprietary Ophthalmic Solution
- Where
- 5 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Presbyopia, Refractive Errors
Evaluation of the Safety and Effectiveness of Aceclidine (LNZ101) and Aceclidine + Brimonidine (LNZ100) in the Treatment of Presbyopia
To evaluate the safety and effectiveness of Aceclidine/Brimonidine (LNZ101) compared with Aceclidine (LNZ100) and vehicle in the treatment of Presbyopia.
- Conditions
- Presbyopia, Refractive Errors, Eye Diseases
- Trial name
- NCT05431543
- Testing
- Aceclidine+Brimonidine combination ophthalmic solution, Aceclidine ophthalmic solution, Vehicle proprietary ophthalmic solution
- Where
- 5 sites in United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- LENZ Therapeutics, Inc
Presbyopia
Assessment of Three Basic Progressive Lens Designs
This clinical trial investigates the differences between three different progressive addition lens designs. It is a non-invasive double-masked randomized clinical investigation. For this study, 80 participants will be recruited.
- Trial name
- NCT05252871
- Testing
- Progressive Additional Lenses (PAL), pre calibrated and made of polymeric material with anti-reflection coating
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Western University of Health Sciences
Refractive Errors, Presbyopia
Assessing the Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
The purpose of this clinical trial is to assess on-eye performance and overall fit of an investigational multifocal toric contact lens to aid in confirmation of the study lens design.
- Conditions
- Refractive Errors, Presbyopia, Astigmatism
- Trial name
- NCT05886907
- Testing
- Lehfilcon A multifocal toric contact lenses, Samfilcon A multifocal toric contact lenses, CLEAR CARE
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Presbyopia
Performance Evaluation of Different Daily Disposable Multifocal Contact Lenses
The objective of the study was to compare the lens performance of two daily disposable multifocal contact lenses.
- Trial name
- NCT05763628
- Testing
- Control Lens (stenfilcon A), Test Lens (senofilcon A)
- Where
- 5 sites in United States, Canada
- Volunteers
- 59 people
- Sponsor
- CooperVision, Inc.
Presbyopia
A Dose-ranging Study to Evaluate the Safety and Efficacy of UNR844 in Subjects With Presbyopia.
Study of safety and efficacy of UNR844 in subjects with presbyopia.
- Trial name
- READER (NCT04806503)
- Testing
- UNR844
- Where
- 20 sites in United States, Australia and 2 more
- Volunteers
- 234 people
- Sponsor
- Novartis Pharmaceuticals
Presbyopia
Study Assessing the Efficacy and Safety of STN1013600 Ophthalmic Solution 0.1% and 0.3% Compared With Placebo in Subjects With Presbyopia
This is a Phase IIa study to assess efficacy and safety of STN1013600 ophthalmic solution (0.1%, and 0.3 %), twice daily when compared to Placebo in subjects diagnosed with presbyopia.
- Trial name
- OPSIS (NCT05665387)
- Testing
- 0.1% STN1013600 ophthalmic solution, 0.3% STN1013600 ophthalmic solution
- Where
- 12 sites in United States
- Volunteers
- 79 people
- Sponsor
- Santen Inc.
Refractive Ametropia
Clinical Evaluation of a Manufacturing Process for a Frequent Replacement Silicone Hydrogel Multifocal Contact Lens
The purpose of this clinical trial was to evaluate the clinical performance of a manufacturing process on a frequent replacement multifocal contact lens.
- Trial name
- NCT05765227
- Testing
- Lehfilcon A multifocal contact lenses, Lotrafilcon B multifocal contact lenses, Hydrogen peroxide-based cleaning and disinfection system
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Alcon Research
Presbyopia
A Clinical Comparison of Two Soft Multifocal Contact Lenses
The study objective was to gather short-term clinical performance data for two soft multifocal contact lenses.
- Trial name
- NCT05794126
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- CooperVision, Inc.