Clinical trials: Presbycusis
Hearing Loss
Evaluation of Hearing Aids Rehabilitation Within Age-related Hearing Loss Population.
Hearing aids restore efficiently some auditory functions in age-related hearing loss (ARHL or presbycusis) providing to the elderly an access to oral communication and a return to social life.
- Trial name
- AGEHEAR (NCT05331404)
- Testing
- PET examination, Quality of life assessment
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Hearing Loss, Presbycusis
Predicting Success With Hearing Aids
The primary complaint of individuals with hearing loss is difficulty understanding speech in the presence of background noise. Although hearing aids help individuals understand speech in background noise better, there is a high…
- Trial name
- NCT00371449
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Age-related Hearing Loss
Prediction of Age-Related Hearing Loss Based on Comprehensive Risk Factors
This study aims to develop a predictive model for age-related hearing loss (ARHL) based on multi-source risk factors and artificial intelligence techniques.
- Trial name
- NCT07612618
- Testing
- Not applicable- observational study
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Age-related Hearing Loss, Cognitive Decline
Auditory-Cognitive Dual-Task Intervention for Older Adults With Hearing Loss
Background: Age-related hearing loss (ARHL) is a common and irreversible condition that has been recently associated with cognitive decline and dementia. Hence, if ARHL is treated earlier, the risk of dementia might decrease.
- Conditions
- Age-related Hearing Loss, Cognitive Decline, Loneliness, Social Isolation
- Trial name
- NCT06486285
- Testing
- Auditory-cognitive dual-task training (ACDT)
- Where
- Hong Kong
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Siderosis, Neurological Disorder
Audiovestibular Function in Infratentorial Superficial Siderosis
One in six people in the United Kingdom and over 400 million people worldwide have disabling hearing loss. This figure will double by 2050 as predicted by the World Health Organisation.
- Conditions
- Siderosis, Neurological Disorder, Rare Diseases, Age Related Hearing Loss
- Trial name
- AViSS (NCT04200664)
- Testing
- Hearing assessment, Vestibular/balance assessment, Quality of life assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University College, London
Age-related Hearing Loss
Hearing Loss and Communication Needs in a Group Care Setting for Older Adults
The purpose of this study is to develop and test a multicomponent hearing care intervention for the PACE staff members in order to learn more about communication and engagement.
- Trial name
- NCT04659967
- Testing
- Virtual Training
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Hearing Loss, Hearing Loss, Age-Related
Sight and Hearing Investigation Into Effects on Delirium
The goal of this observational study is to learn about sensory loss in hospital patients with delirium. The main questions it aims to answer are: Are hearing and vision loss related to increased risk of having delirium? Do…
- Conditions
- Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium
- Trial name
- SHIELD (NCT06176625)
- Testing
- Communication Signage, Amplifier Use
- Where
- United States
- Volunteers
- 1,543 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Presbycusis, Age Related Hearing Loss
Mitochondrial Genetics of Presbycusis
The main goal of this study is to identify mitochondrial mutations associated with presbycusis. Patients affected by severe presbycusis and normal hearing controls (according to ISO7029 norm) will be enrolled if satisfying…
- Trial name
- MITOPRES (NCT03720964)
- Where
- France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Age-related Hearing Loss, PET-CT
PET-CT-based Study of Central Mechanisms of Cortical Metabolism in 18F-FDG and 18F-AV1451 Age-related Deafness
The participants were recruited from elderly subjects in the age range of 60-85 years and audiological assessments, cognitive function assessments, non-invasive brain imaging, behavioral assessments were collected from the normal…
- Trial name
- NCT05796011
- Testing
- hearing aids, without hearing intervention, healthy control
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hearing Loss, Age-Related
Hearing-physical Activity Intervention
Background By 2050, approximately 2.5 billion people are expected to experience some degree of age-related hearing loss (ARHL). Greater ARHL is associated with decreased communication, reduced physical activity and social…
- Trial name
- NCT07071168
- Testing
- hearing-physical activity training
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Hearing Loss, Age-Related
Hearing Aids Use in Elderly: Efficacy in Speech Perception and in Health-related Quality of Life
Background: Prevalence of hearing loss increases over age; its estimated prevalence is 40-50% in people older than 75 years. Recent studies agree that modification in the hearing threshold contributes to deterioration in…
- Trial name
- NCT04333043
- Testing
- audiological test, cognitive questionnaires
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Age-related Hearing Loss, Presbycusis
Genetic Study of Age Related Hearing Loss
Age-related hearing loss, or presbyacusis, is one of the most common chronically handicapped conditions for the elderly. Many factors including genetics, diet, diseases, drugs, socioeconomic factors and environmental variables…
- Trial name
- ARHL (NCT01732289)
- Testing
- genes
- Where
- Taiwan
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Progesterone, Estrogens
Neural Changes in the Aging Auditory System
The purpose of this study was to determine the effects of hormone replacement therapy (HRT) on hearing in post-menopausal women.
- Conditions
- Progesterone, Estrogens, Hearing, Psychoacoustics
- Trial name
- NCT00264407
- Testing
- Hormone Replacement Therapy - HRT
- Where
- 2 sites in United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Frailty, Malnutrition
Impact of Auditory Stimulation in Eating Pleasure (EDERE 2021)
Background. Decreased taste and smell contribute to loss of appetite (anorexia), and the resulting protein-energy malnutrition increases the frailty of the elderly.
- Conditions
- Frailty, Malnutrition, Anorexia, Presbycusis
- Trial name
- EDERE 2021 (NCT04923087)
- Testing
- Compare the noise and pleasure of crunching between two hyperprotein nutritional supplements
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Presbycusis, Frailty Syndrome
Study of the Association Between Presbycusis With the Incidence of Frailty
The objective of the project is to establish the association between presbycusis and the incidence of frailty in humans in order to establish hearing loss with age as another index for the diagnosis of frailty; As well as…
- Conditions
- Presbycusis, Frailty Syndrome, Oxidative Stress
- Trial name
- NCT04360109
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Age-related Hearing Loss, Hearing Loss, Sensorineural
A Prospective Cohort Study On Change of Cognitive Function In Aged-related Hearing Loss With Hearing Aids
Background: Deafness is one of the nine potentially modifiable risk factors for dementia simulated by the Lancet dementia Prevention, intervention and Care Committee in 2017.
- Conditions
- Age-related Hearing Loss, Hearing Loss, Sensorineural, Hearing Aid, Cognitive Function Abnormal
- Trial name
- NCT05694039
- Testing
- Hearing Aids
- Where
- China
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hearing Loss
Early Age-Related Hearing Loss Investigation Pilot Study
The purpose of this clinical trial pilot is to obtain feasibility and pilot data necessary to inform the hearing intervention being designed for a larger R01 clinical trial that seeks to determine whether best practice hearing…
- Trial name
- P-EARLHI (NCT05970211)
- Testing
- Phonak Audeo Lumity Receiver in Canal Hearing Aid
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Hearing Loss, Adult-Onset, Hearing Loss, Age-Related
Hearing Healthcare Assessment in Rural Communities
Adult hearing loss in is the third most common chronic health condition in the United States. Adults living in rural areas face a higher risk of experiencing hearing loss, and more difficulty receiving testing and treatment than…
- Trial name
- HHARC (NCT05786794)
- Testing
- Patient Navigation Program for Hearing Health Care
- Where
- 9 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Matthew Bush, MD
Normal Hearing
The RBANS-H in Older Adults With Normal Hearing or Age-related Hearing Loss
The present cross-sectional study aims to examine the cognitive capabilities of older adults, aged 50 to 89, with normal hearing or age-related hearing loss by means of the Repeatable Battery for the Assessment of…
- Trial name
- RBANS-H_ARHL (NCT03208608)
- Testing
- RBANS-H
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Presbycusis
Hearing and Cognition in Aging Adults
This cohort study is expected to provide valuable insights into the complex interplay between auditory and cognitive functions and how they change over time.
- Trial name
- ACAV (NCT06183450)
- Testing
- auditory level, cognitive level, quality of life level
- Where
- France
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse