Clinical trials: Preoxygenation
Preoxygenation, Apnoea, Anaesthesia
Optiflow Preoxygenation
Optiflow can be used to prolong the apnoea period under anaesthesia without falls in blood oxygen saturation. This study is designed to assess whether the Optiflow system can efficiently replace conventional anaesthetic mask and…
- Trial name
- NCT02981511
- Testing
- optiflow
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Preoxygenation
Preoxygenation and Hemodynamics With Bag-valve-mask and Noninvasive Mechanical Ventilation
Hypoxemia refers to low blood oxygen levels, while hypoxia denotes low tissue oxygen levels. Both conditions pose life-threatening risks when precautions are not adequately taken or when risks are not effectively managed.
- Trial name
- NCT07049666
- Testing
- Bag-valve mask, Noninvasive mechanical ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Baskent University
Inspired Oxygen (FIO2), End-tidal Oxygen (ETO2), End-tidal Carbon Dioxide (ETCO2) and Respiratory Rate (RR) Will be Measured Every 30 Seconds
Comparison of the Classic Face Mask Versus NuMask for Preoxygenation
Currently used face mask has certain disadvantages; such as, not providing a complete seal in certain patients, causing hand fatigue after holding the mask in place for more than a few minutes, causing claustrophobia in an…
- Trial name
- NCT01865851
- Testing
- Classic Face Mask and NuMask
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nimmagadda, Usharani, M.D.
Compare Preoxygenation Methods in Bariatric Patients
Preoxygenation With High Flow Nasal Cannula Prolongs Normoxia Time During Induction of Anaesthesia of Bariatric Patients and is Superior to Conventional Preoxygenation With Face Mask.
To compare preoxygenation for induction of general anaesthesia with High Flow Nasal Cannula vs preoxygenation with face mask in patients undergoing bariatric surgery.
- Trial name
- NCT04965610
- Testing
- Preoxygenation with High Flow Nasal Cannula, Preoxygenation via face mask
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Staedtisches Klinikum Karlsruhe
Obesity
Effect of Different-Flow High-Flow Nasal Cannula Versus Traditional Face Mask Oxygenation on Safe Apnea Time in Obese Patients
Obesity is a growing global health problem, and patients with obesity are at higher risk of hypoxemia during induction of general anesthesia.
- Trial name
- NCT07843810
- Testing
- Face Mask, High-Flow Nasal Cannula
- Where
- China
- Volunteers
- 147 people
- Sponsor
- The First People's Hospital of Lianyungang
Oxygen Deficiency
High-flow Nasal Cannula for Pediatric Anesthetic Induction
Endotracheal intubation in infants often involves more than one attempt, and oxygen desaturation is common. It is unclear whether nasal high-flow therapy, which extends the time to desaturation during elective intubation in…
- Trial name
- NCT05578131
- Testing
- high flow nasal oxygen, face mask
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital
Acute Hypoxemic Respiratory Failure
Comparison Physiological Effects According to Preoxygenation Method Using EIT
Hypoxemia during endotracheal intubation is one of this procedure's most frequent and severe complications, which can lead to cardiac arrest and other adverse outcomes.
- Trial name
- PreoxyEIT (NCT05962073)
- Testing
- HFNC
- Where
- South Korea
- Sponsor
- Samsung Medical Center
Surgery, Desaturation of Blood
Head Elevation During Pre-oxygenation Can Delay Desaturation Time
This study is a randomized-controlled trial study comparing the association between several degree of head elevation and conventional position during pre-oxygenation to desaturation time in patients undergo endotracheal…
- Conditions
- Surgery, Desaturation of Blood, Apnea
- Trial name
- NCT05688722
- Testing
- Supine position, 20 degree head elevation position, 30 degree head elevation position
- Where
- Indonesia
- Volunteers
- 56 people
- Sponsor
- Universitas Indonesia
Anesthesia; Functional
Assessment Through Transcutaneous Brain Oximetry (NIRS) of Two Preoxygenation Techniques
Preoxygenation techniques is currently considered a standard of care, but how they influence cerebral oxygenation remains largely unknown.
- Trial name
- NCT04352049
- Testing
- Preoxygenation
- Where
- 2 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Complexo Hospitalario Universitario de A Coruña
Critical Illness, Hypoxemia
Preoxygenation Using NIV in Hypoxemic Patients
Critically ill patients are predisposed to oxyhaemoglobin desaturation during intubation. For the intubation of hypoxemic patients, preoxygenation using non invasive ventilation (NIV) is more effective at reducing arterial…
- Trial name
- PREOXY (NCT00472160)
- Testing
- Non Invasive Ventilation
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Failure
Four Methods of Pre-oxygenation
Four methods of preoxygenation will be compared in healthy volunteers
- Trial name
- NCT02708862
- Testing
- Preoxygenation
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Hennepin Healthcare Research Institute
Preoxygenation
Can we Improve Preoxygenation by Using Adjustable Pressure Limiting Valve (APL) ?
The aim of this study is to investigate the effects of setting airway pressure release valve (APL valve) on the anesthesia workstation to 5 cmH2O during spontaneous breathing on preoxygenation.
- Trial name
- NCT04010279
- Testing
- preoxygenation with 100% O2, fresh gas flow rate 12 L/minute
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
ICU Patients Under Invasive Mechanical Ventilation
Preoxygenation for Tracheal Aspirations in Intensive Care
Clearing the airways is a complex phenomenon involving the production of secretions, the nature of mucus (viscosity, elasticity, stringiness, and adhesiveness), ciliary movement, and coughing.
- Trial name
- POXTRA (NCT06421012)
- Testing
- Experimental : Patients without additional preoxygenation, Active Comparator : Patients with additional preoxygenation
- Where
- France
- Volunteers
- 2,260 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Preoxygenation
Physiological Effects of Different Preoxygenation Strategies
The goal of this clinical trial is to evaluate the performance and physiological effects of different preoxygenation devices in healthy adult and pediatric volunteers (children aged 5-12 years).
- Trial name
- PREOXY II (NCT07564050)
- Testing
- Nasal cannula (NC), Non-rebreather mask (NRM), Non-rebreather mask (NRM) plus Nasal cannula (NC)
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Preoxygenation
Feasibility of Preoxygenation by Supraglottic Jet Ventilation Before Endotracheal Intubation
The study assumed that supraglottic jet ventilation is an alternative solution as a safe way to do the preoxygenation before endotracheal intubation by contrasting it with mask pressurized ventilation.
- Trial name
- NCT04385511
- Testing
- supraglottic jet ventilation
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Peking University People's Hospital
Anesthesia, Oxygen
PreOxygenation In RSI Anesthesia
Pre-oxygenation with high-flow nasal cannula oxygen has been evaluated in a limited number of studies and seems to be better than traditional preoxygenation with a tight fitting mask.
- Trial name
- PRIOR (NCT02794532)
- Testing
- High-flow nasal cannula
- Volunteers
- 80 people
- Sponsor
- Karolinska University Hospital
Critically Ill
Feasibility of End-tidal Oxygen Concentration Monitoring During Preoxygenation for Intubation in the Intensive Care Unit.
Intubation is a common procedure in the intensive care unit. Hypoxemia is the most frequent complication of this procedure. Monitoring the end-tidal of oxygen is recommended in operating room (OR).
- Trial name
- IMPROVE-Pre (NCT05409573)
- Testing
- double monitoring of EtO2
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Anesthesia, Hypoxia
Assessment of Preoxygenation Strategies in the Prehospital Environment
Comparison of the preoxygenation efficacy of tidal volume breathing using three different preoxygenation techniques which are available to providers in the prehospital environment.
- Trial name
- NCT02694705
- Testing
- Continuous Positive Airway Pressure (CPAP), Bag-Valve-Mask (BVM), Non-rebreather Mask (NRM)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Anesthesia
Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Adults patients scheduled for elective surgery were randomly allocated to receive preoxygenation with spontaneous breathing, positive pressure ventilation (positive inspiratory pressure: 12 cmH2O) without PEEP, and with PEEP…
- Trial name
- PREOX (NCT02313766)
- Testing
- PPV : positive pressure ventilation, PEEP : PPV + PEEP
- Volunteers
- 150 people
- Sponsor
- University Hospital, Caen